DE216901T1 - Immunogenes antigen-traeger-proteinkonjugat zur verwendung in impfstoffen gegen malaria. - Google Patents
Immunogenes antigen-traeger-proteinkonjugat zur verwendung in impfstoffen gegen malaria.Info
- Publication number
- DE216901T1 DE216901T1 DE1986902613 DE86902613T DE216901T1 DE 216901 T1 DE216901 T1 DE 216901T1 DE 1986902613 DE1986902613 DE 1986902613 DE 86902613 T DE86902613 T DE 86902613T DE 216901 T1 DE216901 T1 DE 216901T1
- Authority
- DE
- Germany
- Prior art keywords
- asn
- conjugate
- pro
- ala
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 201000004792 malaria Diseases 0.000 title claims 11
- 229960005486 vaccine Drugs 0.000 title claims 4
- 108090000623 proteins and genes Proteins 0.000 title claims 3
- 102000004169 proteins and genes Human genes 0.000 title claims 3
- 230000002163 immunogen Effects 0.000 title claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 241000223960 Plasmodium falciparum Species 0.000 claims 9
- 206010035500 Plasmodium falciparum infection Diseases 0.000 claims 9
- 229940124856 vaccine component Drugs 0.000 claims 9
- 244000045947 parasite Species 0.000 claims 8
- 150000001413 amino acids Chemical group 0.000 claims 7
- 229960000814 tetanus toxoid Drugs 0.000 claims 5
- 102000014914 Carrier Proteins Human genes 0.000 claims 4
- 108010078791 Carrier Proteins Proteins 0.000 claims 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 239000004475 Arginine Substances 0.000 claims 1
- 101710117490 Circumsporozoite protein Proteins 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 229960003983 diphtheria toxoid Drugs 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 229920005604 random copolymer Polymers 0.000 claims 1
- 210000003046 sporozoite Anatomy 0.000 claims 1
- 239000012646 vaccine adjuvant Substances 0.000 claims 1
- 229940124931 vaccine adjuvant Drugs 0.000 claims 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71696085A | 1985-03-28 | 1985-03-28 | |
| PCT/US1986/000627 WO1986005790A1 (en) | 1985-03-28 | 1986-03-27 | Immunogenic antigen-carrier protein conjugate for use in a vaccine against malaria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE216901T1 true DE216901T1 (de) | 1987-07-23 |
Family
ID=26773520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE1986902613 Pending DE216901T1 (de) | 1985-03-28 | 1986-03-27 | Immunogenes antigen-traeger-proteinkonjugat zur verwendung in impfstoffen gegen malaria. |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE216901T1 (da) |
| DK (1) | DK570386A (da) |
-
1986
- 1986-03-27 DE DE1986902613 patent/DE216901T1/de active Pending
- 1986-11-27 DK DK570386A patent/DK570386A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK570386D0 (da) | 1986-11-27 |
| DK570386A (da) | 1986-11-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69228698T2 (de) | HYBRIDES PROTEIN ZWISCHEN CS AUS PLASMODIUM UND HBsAG | |
| US20060292170A1 (en) | Vaccine Composition Against Malaria | |
| Rutgers et al. | Hepatitis B surface antigen as carrier matrix for the repetitive epitope of the circumsporozoite protein of Plasmodium falciparum. | |
| DE69229107T2 (de) | Peptidsequenzen, spezifisch für die hepatitische phase von p. falciparum, epitope tragend; die die fähigkeit besitzen, die t-lymphozyten anzuregen | |
| KR940000115A (ko) | 고나도트로핀 방출 호르몬(GnRH)에 대한 면역성 캐리어 시스템 | |
| DE3686178T2 (de) | Malaria-impfstoff. | |
| US20060073171A1 (en) | Vaccine composition against malaria | |
| IE860846L (en) | Immunogenic antigen-carrier protein conjugate for use in a¹vaccine against malaria | |
| DE3687071T2 (de) | Malaria-impfstoff. | |
| DE69635077T2 (de) | Gegen malaria polypeptidische molekulen von vorerythrozytären stadium | |
| Pessi et al. | Lack of H‐2 restriction of the Plasmodium falciparum (NANP) sequence as multiple antigen peptide | |
| Audibert et al. | Enhancement by murabutide of the immune response to natural and synthetic hepatitis B surface antigens | |
| DE216901T1 (de) | Immunogenes antigen-traeger-proteinkonjugat zur verwendung in impfstoffen gegen malaria. | |
| Clough et al. | Biologically active antibodies elicited by a synthetic circumsporozoite peptide of Plasmodium knowlesi administered in saline with a muramyl dipeptide derivative | |
| ATE159172T1 (de) | Peptide und deren verwendung | |
| DE69133208T2 (de) | Vier-aminosäurenepitop mit schutzwirkung gegen plasmodium vivax malaria | |
| US20110262469A1 (en) | Malaria vaccine based on fragments and combination of fragments of the cs protein of plasmodium vivax | |
| EP0241725B1 (en) | Improvements in and relating to vaccines | |
| DE69233271T2 (de) | Therapeutischer- und präventivimpfstoff gegen hiv | |
| MY103217A (en) | Plasmodium falciparum merozoite antigen pertides | |
| DE3851310D1 (de) | Synthetische Peptide, die immunologische Aktivität zeigen, benutzbar, um eine Impfung gegen Malaria vorzubereiten. | |
| DE229829T1 (de) | Mit dem plasmodium-vivax-circumsporozoit-protein uebereinstimmendes immunogenes peptidantigen. | |
| DE69014150T2 (de) | Immunogen-Verbindungen und deren Benutzung in der Herstellung von genetisch unbeschränkten synthetischen Impfstoffen und bei der immunoenzymatischer Bestimmung von antisporozoiden Antikörpern von Plasmodium malariae. | |
| DE3723583A1 (de) | Polypeptid, das fuer die herstellung von antimalaria-vakzinen und diagnostische ausruestungen zur feststellung von malariaerkrankungen nuetzlich ist | |
| DD259877A5 (de) | Verfahren zur Herstellung eines Polypeptids für die Prophylaxe von Plasmodium-Infektionen von Säugern |