DE2125862C - Device for mass transfer with a membrane and a method for producing such a membrane diffusion cell - Google Patents

Description

SSSST m

AfedJcfcWPebsftiff io the under the

S ^ fcHn ^ Atjsari

{84 or Wl) the reinforcement position φ »or 95)

6. Device according to one of the claims 1 gekenozeii * ne ^ that * «f *« ead ^ e (M tarn. .101) the amplifier or 103} on every second 4Ϊ each one EfahrtKJll)

ws relieving the tension that arises when folding «the membrane« tSB} together »with the reinforcement layer protrudes inwards

7. Procedure for a device according to one of claims 1 to 6, characterized in that that the reinforcement layer (80 resp.

as 95 or 103) before establishing their connection groove the membrane (10) along the transverse to it, its sections (86 or 99, 102 or 108) separating, possibly notched, fold lines (85 or 104), then

as the membrane lying on the reinforcement layer is connected to it and together with it is folded into rows of pockets (88, 90) opening in opposite directions, whereafter the front ends of the fold walls are tightly connected to one another and the openings of the one and the other row of pockets in the region or portion of the lengthwise direction of the reinforcement layer running cutouts (83 or 100 or 110) of the reinforcement layer at one another

connected to the other separate connecting members (68, 70 and 74, 76) for supplying and removing the media will.

8. A method for producing a device according to any one of claims 1 to 6, or according to

Claim 7, characterized in that the connection is made of poorly adhering material existing semi-permeable membrane (10) with a reinforcing layer (103) made of impermeable Material is produced in that

a tape (114) adhering to both sides along a front surface of the reinforcement layer is attached to this that also the membrane with a in its longitudinal direction running edge overlapping on the tape

is applied and an edge strip of a sealing adhesive (116) on the tape and the applied Membrane edge is applied and that then the reinforcement layer and the membrane together along the crossways to these

SS running fold lines (85 or 104) folded in this way graze that the edge strip is enclosed and squeezed between two fold walls of the membrane will.

The invention relates to au! an improvement and further · training the device of the object del Patents 2 021550. The subject of this

2 12Ü62

! ■ Patents is a device for mass transfer, In particular, the diffusion toe in an oxygenator in a ks kidney, and a vein for the £ Creation of such a device or such a - then diffusion cell,

This device or diffusion outlet is in place a flexible, semi-permeable, on a sight: from one medium to be let through - in particular oxygen or dialysis fluid - on the other Side of a membrane rinsed with a medium that cannot be passed through, which is attached to a reinforcement layer on one side, is preferably connected with a spacer as an intermediate layer, wherein this multilayer structure in equal sections to a plurality of parallel layers and a series of consecutive flaps is folded in such a way that the first medium is in a VirJ number first flow paths and the second medium in a plurality of second Strömunesweee on the one or on the other side of the structure in the one accessible for the first medium on one side Pockets and in those accessible on the other side for the second medium, with the first Pockets alternating pockets can flow, and the reinforcement layer in sections in their Longitudinally spaced cutouts to facilitate feeding tizw. Discharge of the first, preferably gaseous medium through the reinforcement layer to Has membrane or away from it.

Devices of this type are successfully used as extracorporeal oxygenators for blood, in which oxygen and carbon dioxide go in opposite directions through a membrane-like Barrier that separates the blood from the oxygen. Typical for the stand of the art in this area are U.S. Patents 3,370,710, 3,396,849, 3,318,747 and the German application P 19 03 885.8-45 of January 27, 1969 by the applicant (Offenlegungsschrift 1903 885). According to U.S. Patent No. 3,370,710, a pleated, semi-permeable membrane is used Used in conjunction with retaining bolts that compress the membrane folds in Hook condition. The unit formed in this way is fixed in a housing, which is for the flow is formed by blood and oxygen. Within the unit, the blood flows disorderly along its length Flow paths so that there is no choice for a uniform gas exchange.

US Pat. No. 3,396,849 and German Offenlegungsschrift 1908 885 relate to oxygenators with membrane supports in those pockets that are assigned to the oxygen Surface of the membrane are formed. These supports result in orderly flow paths for the Blood along the membrane layers. For example, the supports are in the application mentioned Cross strands formed which result in flow channels for maximum gas exchange. One folded However, membrane is a relatively difficult structure to be set up and monitored precisely, and its manufacture is according to the previously known technique by inserting the membrane supports quite a chore during assembly of the device. The thereby Due to the associated costs, the prices of such known oxygenators are for many interested parties still and steep is a considerable burden for others.

In order to avoid this obsession, as at the beginning and in the Offenlegungsschrift 2021, SSO indicated, a reinforcement layer is connected to the membrane, and this is used to make things easier . the otherwise obstructed supply and discharge of the preferably gaseous medium to one side of the Membrane or away from this provided with cutouts ίο which are arranged in the longitudinal direction of the reinforcement layer spaced from each other was.

According to Offenlegungsschrift 2021 SSO, these sections each extend between a pair »5 successive sections or fields of the reinforcement layer in the transverse direction of the reinforcement layer and the membrane along every other fold lines where the reinforcement layer and the membrane together - preferably ao together with an intermediate spacer layer - to parallel layers and rows of consecutive pockets formed from them are folded that alternately open in opposite directions. The consequence is that The transverse cutouts after the Fold the structure made of membrane and reinforcement layer, narrow transverse slits in the reinforcement layer on the outside of the crests of the folds of the walls of those pockets that extend towards the side of the reinforcement layer to open. The transverse slits extend into the region of the longitudinal edges of the membrane at which these connected to the reinforcement layer, e.g. B. is glued, so that the rinsing the reinforcement layer Medium pass through in these edge areas in one edge area to the membrane and in the flow away from the opposite edge area of the membrane through the reinforcement layer can. This flow process is facilitated in practice that when folding the structure along the folded edges of the pockets facing this medium along the transverse slits and up to the ends of the falling edges a narrow open channel is formed by the fact that the radius of curvature the rigid reinforcement layer at these edges 45 is larger than at the adjacent folding edges Membrane.

This embodiment, which is already greatly improved compared to the known prior art However, the device or the diffusion cell does not fully satisfy 5 ° and still has a relative one low efficiency as a percentage of the medium diffusing through the membrane, z. B. oxygen, because the flow paths along the membrane for this 55 medium are relatively short, namely only from one of the transverse slits on the folded edges go to the next one. Besides, the influx of the medium to the membrane is narrowed in its edge areas and restricted to this, as is the Ab-6o flow at the opposite edge areas, so that a strong uniformly over each of the membrane surfaces distributed flow of this medium is not achieved.

To remedy these still unsatisfactory 63 properties of the training according to the laid-open specification 2021550 seeks the present improvement according to the invention, longer flow paths between the inlet and outlet of the medium

, through the reinforcement layer to the membrane or: from this way with less handicapped and evenly distributed over the Mernbjran area Medium on this side of the membrane '.

Djcses goal, ^ | cr jferfihdung - becomes, \ n "unexpectedly high. Dimensions of a device, the one mentioned at the beginning, Art. The invention is ingenious because the cutouts of the reinforcement layer run in each direction near their longitudinal edges and are arranged at longitudinal and transverse distances from one another.

In one embodiment of the invention, the cutouts are each in one of two adjoining, by a fold line separated from each other sections of the reinforcement layer in Form each attached a longitudinal slot and runs a longitudinal slot in a section close the one longitudinal edge of the reinforcement layer and the next one in the upper longitudinal direction Longitudinal slot in the adjacent section near the other longitudinal edge - preferably parallel to this adjacent longitudinal edge. Instead, the cutouts can also be made in pairs, one close at a time a longitudinal edge of the reinforcement layer, in every other section of this layer or in this way extending at a distance from one another almost over two adjoining sections be arranged.

Further improvements in this connection with the improved design according to the invention the reinforcement layer and its cutouts result from the further claims. This in this context also extend to a with regard to the training according to the invention the device improved method for their production and in particular the connection the reinforcement layer with the membrane, the latter especially in the event that it is made of poorly adhering Material consists.

Embodiments of the invention and its basis are shown below with reference to the drawing Explained in more detail, namely Fig. 1 to 9, to facilitate understanding of the F i g. 10 to 19 a device for mass transfer according to the German Offenlegungsschrift 2021550 and FIG. 10 to 19 embodiments of the invention. It shows fan individual

F t g. 1 in an exploded perspective view of parts of a membrane, a spacer and a steady reinforcement layer TdIe «of a device for mass transfer I of the GffeniegungssCnrSt 2621550,
ig. 2 fine soliauMidGcrie view of the connecting parts eer ρ ig. I ₄
ig. 3 dme scnaubfldficfae DarsteSnog the fore

wT »R- £ Dl 'i ^ H'g pK

on the condition <fer Fig. 1 fbhjenden Stadiam, 4 schaBbadHcfc einn Säömiingsl ^ er of Fig. 9, inso

Device ^ for. Mass transfer after the air traffic control '2, ^ 21550. Or / according to the invention,

Fig. 8 on a coarser scale * a section, through the line 8-8 , aer Fi g. '6, parts being broken away to save space,. ^, _js

Fig. 9 on a larger scale a "section along the line ä-9, the Fig. 6, Wöbet again 'parts broken away sinä, _Λ ",

. Fig. 10Yes, exploded, in perspective ίο illustration of the F i g. 1 corresponding parts of Mass transfer device of an improved design in accordance with the present invention the stiff reinforcement layer,

Fig. 11 shows the three parts of Fig. 10 together built condition,

Fig. 12 is a plan view of part of the in Fig. 10 used stiff reinforcement layer,

Figure 13 is a diagrammatic view of the assembled The structure according to FIG. 11 in the folded ao state in the reverse direction as in FIG. 11 seen,

FIG. 14 is a partial view of a section along the line 14-14 of FIG. 13,

Fig. 15, on a greatly enlarged scale, shows a detail at the top of the detail Fig. 14,

F i g. 16 is a plan view of part of a further embodiment of the rigid according to the invention Reinforcement layer of the device according to the invention,

17 shows a plan view of part of a further embodiment according to the invention of the rigid reinforcement layer of the device according to the invention, <

Fig. 18 is a partial view of the assembled device of Fig. 11 in which the preferred The way in which the membrane is attached to the rigid reinforcement layer is shown, and

19 is a sectional view of the device according to FIG Fig. 18 after folding, in which the constructive Details of the finished seal between the membrane and the rigid reinforcement layer be made clear.

1 shows a piece of the membrane 10, which in this figure has a surface 12 exposed to contact by a blood flow at the top and opposite a lower surface 14 exposed to the gas flow. The membrane 10 provides a means for mass transfer in a corresponding device for mass transfer is, 2. B. a Qxygeuators 16 according to FIG. 7. This membrane iO is flexible "rad bet IialbdurchSssig for the passage of oxygen and Kohlendroxyd Wm different sides * ia opposite SS directions. The oxygenator 16 is suitable for connection aa cm menscaBCaes ^ oitolationssysteni rar «Se DunMührang emer esteafcorporate Oä

g.3 «me fratgiHMEiB» Kciciie das
sens mttoearSttSnatngteili

shtnangsteBe melt Fig. 1 aaegt,
6 case scfaaubua% ä {e view of a Memm aem! "Cnigtmgiiauicuum, aas en

ig. 7 a scfaanb9a1kiie ansk ^ t the

by Bmt. Zd this purpose, as neither tualier below Descnneöen, ansgebSdet ate membrane Iv gas Mittet znr St "sow separation of end media se that blot only betäfert a Obesfläcnel2, iwShrend oxygen (apart from dent durctt the membrane already hmdnrdaje <3asJ nor the Surface 14 is applied.

A membrane ID corresponding to the dimensions The floor of the reinforcement position 18 is thrown through «B» multitude standing across crstreciraidertmdtogjeichem Distance between parallel notches

f "fc

2 1: 2518162

or 'fold lines ^ O weakened; along their thisjVerr The strengthening situation is in a large number of sections that have been carefully considered to be folded-mäfi; sö

'Ends 40, and '42, ", um, so gwei, sentences 44 _% andj46:, vpn eatgegengesetzjen ,,, directions ,. "

Reinforcement layer canoe »for example * from> hardn unites with ^ reference symbols.i.yers ^ hen tsin <L, j Paper 6def> 'Pappö consist, roughly iniidertpicicejirwie .5 T $ ichehj44; $ is with j ^ efebenacf ^ arteiijjv

it ^ is common for ^ tiemdeühöfer «a hydros parting ^ lined.t ^ juneJ ^ iedi

phbber ^ .coating,. «, for example. from ^ golyäthylen djujrch lein &. AusJeiftag, the ausuz

ödrdglirskMn. ^ den Öbe ^ tehen <der5Y ^ rst & rWngs _r Sections ⁷ 62 of. Struc

position 18 applied. The promotion wtrd

installed along the surface 14 of the membrane 10 in the component 24 Ui a

arranges. pre-folded and then expanded again around the

A flexible spacer in the form of a membrane 10 can be accommodated. The component 24 may strip 22 is placed between the surface 14 and then without effort and force and without the reinforcement layer 18. Preferably membrane 10 is folded to damage abrasion, the spacer 22 has the same length, but 15 and is given the shape according to FIG. 3.
smaller width than the membrane 10. The spacer The component 24 folded in this way is easy to handle holder 22 is preferably made of plastic and can be held loosely by hand or in the form of a flow-permeable net or machine: one each also as a spacer Grid on the intersecting, interwoven holders serving so-called flow dividers 48 n or non-interwoven strands, in order to flow ao (Fig. 4, S, 8 and 9) can in each of the pockets 44 to form channels in and along the membrane 10, in Pfeilrichttmg50 (Fig.S) can be used. The flow splitter 48, if the latter thereby against the spacer 22, can be pressed from the same material that pressurized blood can be produced rial as the spacer 22 or other flowing medium along the one after all the flow splitters have been inserted. Surface of the membrane flows A suitable »5, the component 24 is completely pressed together by hand from non-interwoven strands or quantity-pressed, and the ends of the pockets of the existing net have two layers of strands parallel to the opposite ends 52, which lie against one another and which are or 54 (Fig.6) connected to each other and placed in different planes and in seals, such as by dipping into a suitable one of the layers or planes at an angle to the 30 sealing and adhesive means, such as the Above-mentioned strands of the other layer run. Suitable silicone rubber, whereby the component is constantly held by grids or sieve-like spacers with each other's hands or in a machine. As a result, strands of glass fiber are interwoven with a vinyl - the opposite ends of the cover or monofilament polyamide fibers are equally closed - pockets 44 and 46, and if suitable and commercially available, one is produced. Woven membrane unit 64 (FIG. 6), the pockets of which are lattice or sieve-like spacers with interwoven strands that are alternately opened to opposite sides
Embodiment described blood oxygenator
viewed as preferred. DeT spacer 22
can instead be made from a flexible 40
Plastic film or the like. Exist and at which the
The side facing the membrane have projections or ridge-like ribs to thereby form flow channels, the projections preferably only being provided on the side facing the membrane 45 that two spaces 58 (FIG. 8) are provided in each pocket 44 side. between every two adjacent membranate sections

From the in FIG. 1 will consist of one or walls of these pockets. The rooms Intermediate component 24 (Fig. 2) produced, in which the 58 coincide with those edge parts 60 of the Jb & Laadshalter 22 on the membrane 10 adjacent sections of the membrane 10 that are not through the Hegeadea surface 26 of the reinforcement s «associated spacers 22 are supported because

is fastened in such a way that two parallel baal feet are narrower than the membrane. Consequently

28 aad 3Ä along the reinforcement layer 18 «md normal blood pressure in the pockets 44 the

«« Dea. The Be & stigaag kaaa dutch each Blembrteile 60 above the spacer * ^ hiaaus

~ "" - " take place, as in the case of room-tassoa-like inflating, aod indeed at both ends

ggg g

are and a multitude of parallel flow paths on the one hand for blood and on the other hand for oxygen in each form separate pockets.

The length of the flow divider 48 is dimensioned so that the pockets 44 from their inner arc of curvature 56 (F 1 g. 9) are each filled up to their opening. However, the width of the flow parts 48 is about the same as that of spacer 22, so j i R 58 (Fi 8) i jd

vulkamseibarea Si & xm rubber. The § & Säuad S4 (Fig. 7) of the unit64.
0 übeidecfat die Verstarkaagsfage W A Saue-sgeitu6pfe6 is rigid aa the aat of its surface 14 given the Ab- ' iron Setteafche of the Darosioas- or static-JT 22 aa. HereiäaadergegaüberBegeaden ^ Aheit64 so fastened "that each time with ercr off & and M fige the distance between the pockets 46 dMil close"<wtrd and throw aat dea e & tspredtendea Re "o the Ts ^ hea aa dea end" 52 and 54 of the Ernnert 30 of the eyes preferably open, ie not attachable to the head "6

Are covered. The VterttaJerkopffto ItSBt dnea Oxygen inteß68 aad daes oxygenaitsiaetO,

jg g

des ^ tejchea rea Elebininels d ^ bit d / Dfe baäm mässa «erden glejchfatts« rtt 0 aod 42 der Veistärüüv ·

This means that there are additional intervening interferences that are then added by hand

doeo Saoers

det with the otfeaea BadenSt ta ». SSi 46 is id.

A transfer head 72 SSt blood is attached to the other side of the unit 64 may. Br settieS * accordingly each one mhtletai area of the delete 44

tightly and also leaves these pockets open on the Sniä £ nS2 or * 54 of the EftlheU. The distribution head 72 has an inlet 74 and an outlet for the air, which ends with the open ends! 52 or »! 54 de? TäScll®i 44 to connection is * '■ <$ & fiih «- and outlets of the distributing heads 66 and 11 are preferably arranged so that blood and oxygen

In order to enable the passage of Säuerstött through ⁸ IUe reinforcement layers 18, which line the pockets 46, passages or openings are provided in the form of a large number of elongated slots 78 (only a few of which are provided with reference symbols in FIGS. 1, 3 and 9 ) is provided in the arc of curvature of the folds between the sections 62 of the reinforcement layer 18. The ends of these slots 78 extend into the edge strips 28 bcw. 30 and lie in the region of the inlet 68 and the outlet 70 for oxygen. As a result, oxygen can come into contact with the surface 14 of the membrane 10 via the inlet 68, through the reinforcement layer 18 and through the spacer 22.

The embodiment of a device for mass transfer described above is an oxygenator, but the invention is applicable to others as will be apparent to those skilled in the art Use purposes and areas of application, e.g. the device is suitable for mass transfer according to the invention, for example, for use as an artificial kidney.

When used as an oxygenator, the semipermeable membrane of the device is usually made Made of a material impermeable to liquids - the carbon dioxide from the blood and Allows oxygen to pass through to the blood. This material is preferably an elastomeric plastic, such as silicone rubber, which is antithrombogenic or otherwise biologically inert. However, it can also be made on a plastic basis, for example as a mesh or a grid Glass fibers or polyester fibers on which a thin coating of the aforementioned silicone rubber elastomer Other suitable materials for the manufacture of the oxygenator membrane is attached are polyethylene, polytetrafluoroethylene, a cast silicone rubber film, a cast Foil made from a copolymer of silicone rubber, polycarbonate or the like plastic film.

the Verwesdong of the device as kSnstwfed de haTböurchßsage membrane Made from doem material that is the outer protein of the States, however for nitrogenous waste products from ία, Öamsaaxe, tKasser and creatinine;

then aas the roast through the appropriate feaeoiii are CJeBulöse-

10

lässjgäi; & eiftb ^^ ate

itetteto brave «de * Pappe te m ^ i-Mw Ws stwa tp§ öissipiBfflii ^l * eöü | piü3 ^^ g ^ B | c ^ nm bed ^ t ^ tköicMaefli * ä && uni ie | “PliÄ% t depends on the dissipated material. The. Vi & sjtärkungslägMÄ can also consist of "other" material, for example plastic such as polypropylene

gummiemmifexölmätys ^
ι «stiff paper or cardboard are preferably provided with a coating of a plastic, such as those mentioned above, or silicone rubber.

The spacer 22, which the flow channels in the folded layers of the semi-permeable Membrane creates and limits it, can be sandwiched between the membrane and the folded reinforcement layer be inserted; it can be on one or both side areas of the folded reinforcement layer be attached or from one embossed on one or both side areas of the reinforcement layer 18 or surface provided with projections. Such training can go through Glue strands, grids or nets to the surface of the reinforcement layer 18. Instead of this, the reinforcement layer 18 can in turn be formed with a shaped surface which has strand-like or other irregularities that correspond to the flexible spacer 22 and in one piece, e.g. B. by pressing the formable surface of the reinforcement layer 18 are formed. Such a union of a reinforcement layer 18 and a spacer 22 into a single piece or a layered one Formation results in a substantial further simplification of the association and corresponding cost savings Assembling the device.

The attachment of the spacer to the reinforcement layer 18 and / or the attachment of the reinforcement layer the membrane can be screwed, wrapped with tape or the like or through Use of adhesives such as silicone rubber, epoxy resin adhesive and similar adhesives, which are compatible with the material of the surfaces concerned. To the spacers 22 and the Siröniuagsieilern 48 suitable To provide flexibility, this can be done using materials such as low density polyethylene, vinyl, or vinyl coated fiberglass can be used.

FIGS. 10 to 19 5, described below, show the FIG. to 9 corresponding general structure of the device

Zur MaS & cüuDcalärtjjiikMifc AwjfjilnjiMi ^ dii ^ jiqy'fi »der

suspension. Dating are in the pig. 10 to 19 ones Tefle, the parts of the Pig. Ϊ «rad 7 to SS correspond to or are the same, with the same conditions. OTgszeiciien (like 10, IS, 22 ...).

Fig. 10 show up tefle IS a "MasseöüberanesvorrichtunB that in, äfleemeiäeii similar

Flow of the baäm media in the te feeBefeigss: Direction neialw egäBaaätx TSSi * & Ifcin

in the R ^ eI in countercurrent to des the described is the m Fig. Ibis 9 shown in the iedocheme

β »Vra ^ rkungslageSe (the int augerndnea of the market

S6Äungslage IS of the above-described Aosbil-

duagsfonn et ant SsmtitaSmsk M form of

Let VetsSrJoaigsfage £ 8, which is provided for the LSagsschHtzen82, 83, which run adjoining «ad along the fJngsfraffieagi of the sections« 5 of the V88. It is the purpose of these excerpts 82 * 83 that the * * ""' dhtrns zo and effluent from the seoo

of the folded layers of the half-cut each in the "tar " ΰΆ between

ii ■. ■ # ₁₂

Membrane 10 and reinforcement layer 18 to lighten! Along the membrane 10 for an effective tern. To make the reinforcement layer similar to <the mass transfer process,
previously described Äusrühnm $ siöfin falter, zu The reinforcement layer 80 is additionally with. medium-

are transverse fold or notch lines 85 in front of cutouts 96 running in the transverse direction seen. S provided »the. stand at a distance from the long edges

Figures 10 and 11 are similar to Figures 1 and 2; they extend along the reinforcement layer 80., every second in FIG. 2 each show the membrane 10 and the fold or fold line of the holder 22 with the reinforcement layer corresponding to the reinforcement layer 18. This cross-cut-out reinforcement layer 80. The parts 10, _{i {} M had the task of ensuring the presence of a 22, 80 similar to the parts 10, 22, 18 previously undesired flow path with little stress. It is possible in the folded flow resistance to prevent the use of a straight-line space 97 (if not a membrane device also flow dividers, remedied by means of a cutout 96 such as 48, if this is desired) by means of a straight space 97 (Fig. IS)

Figures 13 and 14 show the assembled, between the apex of the fold and the crook, respectively Not yet completely folded up the device of the reinforcement layer 80 and the abin reverse position (than in Fig. U) in which the stand holder 22 is formed. This straight one Reinforcement layer 80 at the top and the membrane 10 and space are created in that the spacer 22 the spacer 22 are below. The upwardly often not so sharp folded edge or curvilinear Pockets 88 and which can be directed downwards at the fold, like the reinforcement layer The pockets 90 are folded through the folded ver ao 80, so that the said straight-line free space Forms reinforcement layer 80 and the other associated parts.

educated. It can be seen that the medium which occurs in the formation of this space, so he represents

any set of pockets 88 inserted into a low flow impedance flow path, through the reinforcement layer 80 and stood up from the inlet 92, allowing the medium then to flow along the spacer 22 in each case in the as to the outlet 94 without it being intimate curved space in the arch between and a film-forming contact with the meme reinforcement layer 80 and membrane 10 flow in brane 10 arrives as the medium must, if must, so that a mass exchange with the through which it flows along a flow path that is deeper Bags 90 flowing medium takes place. The cutouts run within a pocket 88

The cut-outs 82, 83 create an inflow path 30 96, during the manufacture of a small medium flowing for a larger amount by dripping an adhesive sealant. 98 the reinforcement layer 80 through to the membrane 10 (FIG. 1S) in this way into the cutouts 96. ■ ·., With greater distribution over the membrane surface. that the rectilinear flow space 97 is closed. In use, the mass transfer device is so that the transfer properties of the device according to FIG.
the flow path along the membrane 10 in FIG. 16 is another embodiment of a

knowledge is narrowed down. This constriction is represented by rigid reinforcement layer 95 which can be used in place of the selected locations through cutouts 82 of reinforcement layer 80. 83 reduced, due to the relatively large distributor head- each section of a series of sections 99, the like zones in the area of the membrane and 40 each with sections 102 of the reinforcement layer 95 spacer adjoining the cutouts 82, alternate with two each in the longitudinal direction 83 are formed. This provides a rapid distribution of the reinforcement layer extending cutouts of the reinforcement layer 80 and cutouts 82 flowing into each pocket through the inlet 100, each of which is arranged one of the two openings 92 on the surface of the folded longitudinal edges 101 of the reinforcement layer In the sections 102, which alternate with the sections 99 from the medium and a uniform collection of the measuring medium, there are no cut-outs provided for the medium extending in the cutouts 83 and the outflow of the medium extending in the longitudinal direction of the stiffening layer through their outlet openings 94,
The reinforcement layer according to Fig. 16 has a

So z. B. gas more oxygen ia such a 50 notched or folded fold or fold lines 85 forced folded area, which is constructed in contrast to the areas 99 and 100 shown in FIG Verteaerkopf rieC 8Bd arrives from this running cutout 96, the cutouts 9 € in the Öfirangen92. To the extent that the reinforcement layer aach Fig. 12 absfidt are and cuts 82 enejdxten reduction of the narrowing S3 are used for the same purposes,
If the SaneKtoS or another medium flows in FIG. 17, a further inlet shape is shown rapidly through the rigid reinforcement layer BB within the seams 82, the charged zone each at the bottom. Vtae there, instead of the vorstdienul) eaäiiebenen vejassrknngs-oxygen crosses, but and between the membrane tt lay with eaoer invented masses but at the reinforcement layer80 so that Amsdmiaen83 te trstang can be used. Ie "ad experiences while other MembraneIO else over- Vrsslage WBS has Fäiz- or Fauliniei transmission. Then the medium wad in the tarnished and matted areas, in the ridges of which crosswise to the layer, areas extending across the surface HS, which collects the scant, from where the remaining 96 of the above-mentioned reinforcements 94 flow out and, if n but iron Sj layers are similar. Zmalzlfl & is each of the section SarimielkopfCFig. 7) derived from the design 108 since a pair of cutouts UO is provided. This & _ designed system, each of which in each dsm section does pairs sclia & t a bxtifta, jpridenSSgen Suöiuuugsweg of sections Obergi ^ · ¹ Ow in the neighboring)

is appropriate. Here, however, §

afta? Pairs of cutouts 3Ü0 one

^, __ KözEnietO *, which is followed by such a Φεια, in which such cut-outs 110 are also at a distance from this fold line above. Accordingly, the cut-outs 110 of each pair of a section 108 each go into <£ s those cut-outs 10 above, in which the one adjacent PbM are provided and are not seen m in those proposed in the other benachbaäen field. This design creates a low degree of distribution of the flow of the medium through the rigid reinforcement layer and evenly through the spacer 22 to the membrane 10; seeping through JSBt and jy promotes the transition through the membrane.

If desired, additional extrusions or incisions 112 can be made from the longitudinal edges of the reinforcement layer at every second of the fold lines or fold lines to ao extend inside and serve to reduce the stress on the membrane when they are together is folded with the reinforcement layer. Since the outside center 106 can be used to create access to fill in the straight space that is may have formed between the membrane and the spacer and the reinforcement layer, the outside center 112 should serve to relieve the membrane at a point where it Otherwise, when the structure is folded, a strong tension is experienced, in this way a tearing of the membrane to avoid. The aforementioned tension is increased by the fact that the membrane usually is wrapped with a tape running between the reinforcement layer and the membrane and in their location is maintained, reducing the radius of curvature of the diaphragm when turning on those Falüinien 104, on which the appearance center 112 are provided, is increased. Through these cutouts 112, this tension is reduced in the area in which the attachment the tape or an adhesive strip or adhesive bead creates an undesirably large amount of tension the membrane would cause.

18 and 19 show an advantageous method of applying such a tape or self-adhesive tape or adhesive flange strip 114 for connecting the membrane 10 to a reinforcing layer 103. Bonding the membrane to the reinforcing layer can be a difficult task, especially when cellulose meme sssta

spread and easily

bran, 1.0 ajtf den Kieosneiicu »ϋί>« »~ · - -

ijerabgediüekt. Then a vulcanizable or curable flexible Klebstofi, for example, a vulcanising 2arnmerCemperatur elastomeric SiScon-S ^ autschuk, the Oberan adhesive side fnäang in the form of an edge strip 116 of the tape put up 114 so that m the edge of the resting on the belt 114 membrane ί " The reinforcement layer 103 (in FIG. 18) or 18, 103 Qa Flg. 19), the membrane spacer and the membrane 10 are folded together in the usual manner along the transverse fold lines 104 so that the uncured edge strip 116 of adhesive between adjacent fold walls of the membrane 10 is gripped and squeezed. This provides a good side seal for each of the pockets formed by the membrane 10 after folding. The edges of the membrane 10 are in turn encompassed and clamped by the longitudinal sections of the tape 114, the tape 114 in turn being encompassed and clamped by the edge of the reinforcement layer 18 or 103, so that a strong, leak-tight seal results , even if it may not adhere strongly to the adhesive edge strip 116, held in place by the snap fastener as soon as the adhesive and sealant of the edge strip 116 is or has been vulcanized or cured after the folding process.

The above-described transmission device for masses or media or for exchange of media generally forms a disposable and replaceable unit in after use an ordinary oxygenator housing, oxygenator container or other oxygenator frame, and this device or unit can be used in the same way as a disposable unit in a complete artificial kidney machine, in which the collected discharge the outflowing media or the distribution of the supplied media by means of conventional discharge or supply elements is effected.

For this purpose 2 sheets of drawings

Claims (4)

2 121 MS Patent claims: Device for mass transfer, insboere Dfiision signal in an oxygenator pure fconstfiebee rfiere, with a flexible one Membrane and a continuous vertebral structure arranged on its legs together the membrane must be drawn in is aod] zn this mba page immediate openings in Perm from Aiisse & nit-1 A first medium was needed for Bairch's step in a multitude of parallel first streams * io shape of bags flow fcaan * a second medium in a cattle second flow paths in the form of pockets that flow through the membrane from the first flow paths are separated and are located between them, the sections of the Reinforcement lie in pairs between each two adjacent layers of the membrane and these over supported on this adjacent support members, between which the flow paths run after Patent 2021 SSO, characterized in that the cutouts (82 or 83, 100 or 110) in the longitudinal direction of the reinforcement layer (JBO or 95 or 103) near its longitudinal edges (84 or 101) and are arranged at longitudinal and transverse distances from one another. 2. Device according to claim I, characterized in that that the cutouts are in one of two adjoining sections separated from one another by a fold line (85) (86) of the reinforcement layer (80) in the form of a respective longitudinal slot (83 or 82) are, and each a longitudinal slot (83) in a section near the one longitudinal edge (84) of the reinforcement layer and the next longitudinal slot (82) in the adjacent one in the longitudinal direction thereof Section near the other longitudinal edge (84) - preferably parallel to this adjacent one Long edge - runs. 3. Device according to claim 1, characterized in that that the cutouts in pairs in every second (99) of the successive sections (99, 102) of the reinforcement layer (9S) in Form of pairs of longitudinal slots (100) are attached, each of which is close to the upper one and one near the lower longitudinal edge of the reinforcement layer - preferably parallel to this edge - runs. 4. Device according to one of claims 1 to 3, characterized in that the cutouts in the form of longitudinal slots (110) aligned in pairs, each in two adjoining sections (108) separated from one another by a fold line (104) the reinforcement layer (103) are provided so that two near one of the longitudinal edges (101) running and each two near the other longitudinal edge (101) running, adjacent and with one another aligned slits (110) merge over said fold line (104), however at a distance from the longitudinal slots of the sections adjoining them outside of said sections Sections end. $. Device according to one of Claims 2 to 4,