DE212020000639U1 - Membrane Structured Virus Detection Laboratory, Biosafety Laboratory and Ground Cover Virus Detection Laboratory - Google Patents

Abstract

Foil structured virus detection laboratory, comprising:
- an inflatable film structure (1) inflatable to form a house body or a tubular body, wherein the inflatable film structure (1) upon inflation forms a functional space (19), therein a clean room (2), one or more auxiliary functional areas serving buffer units (3) and a heavily soiled area (4) serving as the main functional area are provided, wherein the buffer unit (3), which is defined by the inflatable film structure (1), separates the clean room (2) from the heavily soiled area (4) and an inner an opening and closing door (33) configured to airtightly separate or connect the buffer unit (3) from the clean area (2) and the heavy pollution area (4);
- an input device-integrated module (5) which is arranged at one end of the functional space (19) and has at least one input door (51) which is airtightly separated from or connected to the clean room (2); and
- an output device-integrated module (6) which is arranged at the other end of the functional space (19) and has at least one garbage disposal case (61); wherein at least one of the input device-integrated module (5) and the output device-integrated module (6) further comprises a two-way heat exchanger fresh air blower with a filter device, which is arranged to supply air to the functional space (19) or from the functional space (19) and with which the heavily soiled area (4) in a negative pressure environment is converted.

Description

technical field

The present utility model relates to the field of buildings with protective insulation, and more particularly to a membrane-structured virus detection laboratory, a biosafety laboratory having the above membrane-structured virus detection laboratory, a ground-covering virus detection laboratory having the above membrane-structured virus detection laboratory, and a ground-covering virus detection laboratory having the above biosafety laboratory.

State of the art

After the outbreak of a large-scale epidemic in early 2020, there has been a great demand for epidemic prevention hospitals, mobile cabin hospitals, or places of refuge and isolation. In addition, the virus testing labs (or biosafety labs) used for virus testing and research were also seriously inadequate.

Biosafety laboratory is a laboratory built through regulated laboratory design, configuration of laboratory equipment, use of personal protective equipment, etc. Whenever there is an outbreak or related event, the relevant samples (including human, animal, environmental samples, etc.) collected on site must be sent quickly to the biosafety laboratory for potential biological risk factors (pathogens , toxins, etc.) to detect and identify, which can effectively support on-site scientific decision-making and rapid response.

The traditional virus detection labs mostly use traditional prefabricated building structures and require a negative pressure system to treat the indoor polluted air. This has led to problems, e.g. B. High implementation costs, longer construction cycles, difficulties in dismantling after completion, impossibility of packing and storage, difficulties in site selection, etc. When an epidemic outbreak occurs on a large scale, the requirements for the flexible and timely establishment of the existing traditional virus detection laboratory or biosecurity laboratory cannot be fulfilled.

Therefore, there is an urgent need for a virus detection site that can be set up quickly and easily and that meets the higher level of biosecurity.

Public Content

A purpose of the present utility model is to solve, at least to some extent, one of the above technical problems in relevant technologies. To this end, the present utility model presents a membrane-structured virus detection laboratory that can be highly integrated and set up quickly.

The present utility model also presents a biosafety laboratory with the above-mentioned membrane-structured virus detection laboratory.

The present utility model also provides a ground-covering virus detection laboratory with the above-mentioned membrane-structured virus detection laboratory.

The present utility model also provides a ground covering virus detection laboratory with the biosecurity laboratory mentioned above.

The membrane-structured virus detection laboratory according to the first aspect of the present utility model includes an inflatable sheet structure, an input device-integrated module, and an output device-integrated module. The inflatable sheet structure is inflatable to form a house body or a tubular body. After inflation, the inflatable film structure can form a functional space, in which a clean room, one or more buffer units serving as auxiliary functional areas and a heavily soiled area serving as the main functional area are provided. The buffer unit defined by the inflatable sheet structure separates the clean room from the heavy pollution area. The buffer unit has an inner opening and closing door configured to airtightly separate or connect the buffer unit to or from the clean area and the heavy pollution area. The input device-integrated module is arranged at one end of the functional space and has at least one entrance door airtightly partitioned from or connected to the clean room. The output device-integrated module is placed at the other end of the function space and has at least one waste disposal case. At least one of the input device-integrated module and the output device-integrated module further includes a two-way heat exchanger fresh air blower with a filter device, which is configured to supply air to or exhaust air from the functional space, and with which the heavily polluted area is converted into a negative pressure environment will.

According to one embodiment of the membrane-structured virus detection laboratory, the modular structure of the laboratory can be achieved by arranging the input device-integrated module and the output device-integrated module, which advantageously enables central management of the devices. Further, the rapid construction of the membrane-structured virus detection laboratory is advantageously realized that the inflation of the inflatable sheet structure can form the house body or the tubular body. Therefore, the membrane-structured virus detection laboratory can be put into operation as soon as possible. In addition, the negative pressure environment of the heavy pollution area is conducive to ensure the safety of virus detection.

According to some embodiments of the present utility model, the buffer unit and the clean room are both in negative pressure environments. The clean room, the buffer unit and the heavy pollution area satisfy a pressure relationship: clean room > buffer unit > heavy pollution area.

According to some embodiments of the present utility model, the membrane-structured virus detection laboratory further comprises at least one air column tube. One end of the air column tube extends into the functional space, and the other end of the air column tube is connected to the corresponding two-way heat exchanger fresh air fan.

Further, on the air column tube are defined a first air passage opening communicating with the clean room, a second air passage opening communicating with the buffer unit, and a third air passage opening communicating with the heavy pollution area.

According to some embodiments of the present utility model, the two-way heat-exchanger fresh air blower includes an inlet-side two-way heat-exchanger fresh air blower belonging to the input-equipment-integrated module and an outlet-side two-way heat-exchanger fresh-air blower belonging to the output-equipment-integrated module.

Further, at least one of the input device-integrated module and the output device-integrated module includes an outdoor air conditioning unit, and an indoor air conditioning unit is provided in the functional space.

For example, the air conditioning outdoor unit includes an inlet-side air-conditioning outdoor unit belonging to the inlet-equipment-integrated module and an outlet-side air-conditioning outdoor unit belonging to the outlet-equipment-integrated module.

Further, the input equipment-integrated module includes an input equipment frame on which the input-side outdoor air conditioner unit and the input-side two-way heat-exchanger fresh air blower are set.

According to some embodiments of the present utility model, the input device-integrated module further includes a waste water tank placed on the input device rack.

According to some embodiments of the present utility model, the entrance door, which is designed as an intelligent interactive entrance door, can be opened and closed without contact.

According to some embodiments of the present utility model, the outlet equipment-integrated module further includes an outlet equipment frame on which the outlet-side outdoor air conditioner unit and the outlet-side two-way heat-exchanger fresh air blower are set.

According to some embodiments of the present utility model, the output device-integrated module further includes an escape door airtightly separated from and connected to the heavy pollution area.

According to some embodiments of the present utility model, a smoke alarm system is disposed in at least one of the clean room, the buffer unit, and the heavy pollution area.

According to some embodiments of the present utility model, a powder extinguisher is disposed in at least one of the clean room, the buffer unit, and the heavy pollution area.

According to some embodiments of the present utility model, one or more air disinfection devices are provided in the heavy pollution area, including one or more of a plasma disinfection device, an ultraviolet ozone generator, a dry mist hydrogen peroxide sterilizer.

According to some embodiments of the present utility model, the buffer unit includes a first changing room and a second changing room which are independent from each other and each have an inner opening and closing door.

Further, an inlet passage is defined by the entrance door, the inner opening and closing door between the first changing room and the clean room, and the inner opening and closing door between the first changing room and the heavy pollution area, and by the inner opening and closing door between the second changing room and an outlet channel is defined in the heavy pollution area, the inner opening and closing door between the second changing room and the clean room, and the entrance door.

According to some embodiments of the present utility model, the opening and closing of the inner opening and closing door is performed using any one or a combination of zipper, magnetic attraction, adhesion, hooks and buckles.

According to some embodiments of the present utility model, a lighting band is arranged in the functional space, which is attached to the inflatable foil structure by means of a Velcro fastener and/or bandage.

According to some embodiments of the present utility model, the inflatable film structure includes an inflatable dome structure and an inflatable isolation structure, wherein the functional space is defined by the inflated dome structure and the buffer unit is defined by the inflated isolation structure.

In accordance with some embodiments of the present invention, the inflatable dome structure includes a plurality of closely spaced arcuate inflatable rings, the inflatable ring having an internal pressurized air film space.

Furthermore, a single layer of film covers an inside of the inflatable ring.

According to some embodiments of the present utility model, the inflatable dome structure comprises a support frame on its outside and a single-layer sheet or double-layer sheets on its inside, wherein the single-layer sheet is configured to form a positive air pressure film space between the single-layer sheet and the support frame, and wherein the double-layer Foils have a positive air film space inside.

According to some embodiments of the present utility model, the inflatable dome structure includes an air column frame composed of a plurality of air columns with positive air film space inside, and the outside of the air column frame is covered with a single-layer film or double-layer films with positive air film space.

According to some embodiments of the present utility model, the inflatable sheet structure includes an air film space, a sheet structure fill port, and a sheet structure air outlet. The film structure fill opening and the film structure air outlet are in communication with the air film space. A blower is connected to the foil structure fill opening and configured to blow air into the air film space. An air inlet at the film structure fill opening is larger than an air outlet at the film structure air outlet, so the air film space is a positive air film space.

According to some embodiments of the present utility model, the heavy pollution area is equipped with a humidifier to meet humidity needs, and/or one or more skylights are provided on top of the heavy pollution area for lighting or ventilation, with an inward-facing disposable filter device disposed on the skylight.

According to some embodiments of the present utility model, the heavy pollution area has a first transfer port and a second transfer port suitable for setting transfer units.

Optionally, the transfer unit is a transfer box and/or staff access box.

According to some embodiments of the present utility model, the transfer unit and the garbage disposal case each include an inner door facing the heavy pollution area and an outer door facing outward. The transfer unit and garbage disposal case use intelligent interaction technology to form an intelligent interlocking structure through the inner door and the outer door to avoid opening the inner door and the outer door at the same time.

According to some embodiments of the present utility model, the inflatable sheet structure is folded and stored by suction.

According to some embodiments of the present utility model, the inflatable sheet structure is improved in properties or converted into a permanent building by one or a combination of spraying the building materials, pouring concrete, and covering the vegetation on the outer surface of the inflatable sheet structure.

According to a second aspect of the present utility model, the biosafety laboratory comprises a plurality of membrane-structured virus detection laboratories according to the first aspect of the present utility model, wherein the second transfer port of a membrane-structured virus detection laboratory and the first transfer port of an adjacent membrane-structured virus detection laboratory are aligned and connected to each other.

According to some embodiments of the present utility model, two membrane-structured virus detection laboratories are provided. The second transfer port of a first membrane-structured virus detection laboratory and the first transfer port of a second membrane-structured virus detection laboratory are aligned and connected to each other.

According to some embodiments of the present utility model, the heavy contamination area of the first membrane-structured virus detection laboratory is a sample receiving and preparing area, and the heavy contamination area of the second membrane-structured virus detection laboratory is an amplification area.

According to some embodiments of the present utility model, the first port of transfer of the first membrane-structured virus detection laboratory is a first sample import, and the second port of transfer of the second membrane-structured virus detection laboratory is a second sample import.

For example, a sample inactivation zone, a sample unpacking and information verification zone, a sample tube transfer zone, and a sample preparation zone are provided in the heavy pollution area of the first membrane-structured virus detection laboratory to fulfill the sample acceptance and preparation process.

A drying box is also provided at the sample inactivation zone, in which the sample is inactivated. A first biological safety cabinet is provided at the sample unpacking and information verification zone where samples will be unpacked and information verified. A second biosafety cabinet is provided at the sample tube transfer zone in which a sample tube is transferred. A sample nucleic acid extractor for automatic sampling of the nucleic acid is provided at the sample preparation zone.

Optionally, a centrifuge, a refrigerator, a printer, an oscillator or a combination thereof is provided in the first membrane-structured virus detection laboratory.

Optionally, the drying box is arranged next to the first sample import.

According to some embodiments of the present utility model, a nucleic acid amplifier is provided for performing the sample amplification process in the heavily contaminated area of the second membrane-structured virus detection laboratory.

Optionally, a centrifuge, a refrigerator, a printer, an oscillator or a combination thereof is provided in the second membrane-structured virus detection laboratory.

According to some embodiments of the present utility model, the dry box, the first biological safety cabinet, the second biological safety cabinet, the sample nucleic acid extractor, and the nucleic acid amplifier are used in sequence.

Optionally, an autoclave for sterilizing medical waste is further provided in the heavy pollution area of each of the first membrane-structured virus detection laboratory and the second membrane-structured virus detection laboratory.

According to some embodiments of the present utility model, at least one first auxiliary laboratory for supporting the sample receiving and preparation process is provided on the opposite side of the first membrane-structured virus detection laboratory to the second membrane-structured virus detection laboratory, and at least one second auxiliary laboratory for supporting the amplification process is on the side opposite to the first membrane-structured virus detection laboratory of the second membrane-structured virus detection laboratory. The first auxiliary laboratory and the second auxiliary laboratory are both the membrane-structured virus detection laboratory.

In the biosafety laboratory according to the second aspect of the present utility model, safety of use of biosafety laboratory can be advantageously improved by achieving physical separation of each functional area by transfer unit. If, for example, a leak of amplified nucleic acids occurs in the amplification area, the leaking nucleic acids can be prevented from reaching the sample acceptance and preparation area.

A ground covering virus detection laboratory according to a third aspect of the present Utility model includes the membrane-structured virus detection laboratory according to the first aspect of the present utility model. By one or a combination of spraying the building materials, pouring concrete, and covering the vegetation on the outer surface of the inflatable sheet structure, the membrane-structured virus detection laboratory can be converted into a permanent and ground-covering building.

A ground-covering virus detection laboratory according to a fourth aspect of the present utility model comprises the membrane-structured virus detection laboratory according to the second aspect of the present utility model. By one or a combination of spraying the building materials, pouring concrete, and covering the vegetation on the outer surface of the inflatable sheet structure, the membrane-structured virus detection laboratory can be converted into a permanent and ground-covering building.

The additional aspects and advantages of the present utility model will be set forth in part in the following description and in part will be apparent from the following description or learned through practice of the present utility model.

character list

• 1 Figure 1 is a schematic representation of a biosafety laboratory.
• 2 Figure 12 is a schematic representation of a biosafety laboratory with an inflatable foil structure being removed.
• 3 Figure 12 is a schematic representation of the interior of a biosafety laboratory.
• 4 12 is a cross-sectional view of an inflatable dome structure according to a first embodiment.
• 5 12 is a cross-sectional view of an inflatable dome structure according to a second embodiment.
• 6 12 is a cross-sectional view of an inflatable dome structure according to a third embodiment.
• 7 12 is a plan view of an inflatable dome structure according to the third embodiment.
• 8th Figure 12 is a schematic representation of a staff flow line in a biosafety laboratory.
• 9 Figure 12 is a schematic representation of an instrument flow line of the instruments in a biosafety laboratory.
• 10 Figure 12 is a schematic representation of a material flow line in a biosafety laboratory.
• 11 12 is a schematic representation of a biosafety laboratory according to another embodiment.

Reference sign

Inflatable sheet structure 1; inner foil 11; outer foil 12; monolayer film 13; inflatable ring 14; support frame 15; support air column frame 16; supporting air column 161; air film space 17; film structure air outlet 18; function room 19; clean room 2; buffer unit 3; first changing room 31; second changing room 32; inner opening and closing door 33; heavy pollution area 4; first transfer port 41; second transfer port 42; intermediate material transfer box 43; feedstock transfer box 44; personnel access box 45; input device integrated module 5; entrance door 51; inlet-side two-way heat-exchanger fresh air blower 52; inlet side air conditioning outdoor unit 53; input rack 54; waste water tank 55; blower rack 56; output device integrated module 6; garbage disposal case 61; two-way heat exchanger outlet side fresh air blower 62; outlet side air conditioning outdoor unit 63; output rack 64; escape door 65; air column tube 71; air conditioning indoor unit 72; air disinfection device 73; lighting band 74; centrifuge 81; refrigerator 82; printer 83; oscillator 84; autoclave 85; first membrane-structured virus detection laboratory 10; drying box 101; first biological safety cabinet 102; second biological safety cabinet 103; sample nucleic acid extractor 104; second membrane-structured virus detection laboratory 20; Nucleic Acid Amplifier 201.

Description of the embodiments

The embodiments of the present utility model will be described in detail. Exemplary embodiments are illustrated in the drawings, in which everywhere the same or similar reference symbols designate the same or similar elements or elements with the same or similar functions. The embodiments described below with reference to the drawings are exemplary and are intended to explain the present utility model, but should not be construed as limiting the present utility model.

In the present utility model, unless clearly specified and otherwise limited, the term "installed", "connected", "attached", etc. should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection or an integrated part; a mechanical connection, an electrical connection formation or mutual communication; indicate a direct connection, an indirect connection via an intermediate medium, an internal communication between two components, or an interaction between two components. Those skilled in the art can understand the specific meanings of the above-mentioned terms in the present utility model according to the specific circumstances.

The construction system with an inflatable film structure is an innovative construction technology developed over the years, which has the advantages of fast construction speed, high cost-effectiveness, convenient storage, high compression ratio, fast transportation, etc. Therefore, the construction system with the inflatable foil structure is suitable for the allocation of resources between cities. Besides, it can facilitate the timely large-scale production and build with the existing production systems.

The following describes in detail a membrane-structured virus detection laboratory according to an embodiment of the present utility model with reference to FIG 1 until 11 .

According to a first aspect of the present utility model, a membrane-structured virus detection laboratory may include an inflatable film structure 1, an input device-integrated module 5, and an output device-integrated module 6, as shown in FIG 1 until 3 shown. The inflatable sheet structure 1 is inflatable to form a house body or a tubular body.

As in 2 until 3 shown, the inflatable film structure 1 can form a functional space 19 in which the experimenter can detect viruses and do other auxiliary work, e.g. B. change of protective clothing. The inflatable sheet structure 1 is formed into a shape after inflation to achieve the rapid construction of the functional space 19 . For areas that require large amounts of detection, the detection pressure can be significantly reduced in a short time by using the quickly set up and membrane-structured virus detection laboratory. In addition, the inflatable film structure 1 can be removed after deflation. This allows the membrane-structured virus detection laboratory to be removed after the detection task has been completed in order to free up space there.

As in 2 until 3 shown, a clean room 2 , a heavily soiled area 4 and one or more buffer units 3 are provided in the functional room 19 . The buffer unit can serve as an auxiliary functional area in which, for example, the exchange of protective clothing can be carried out. The heavily contaminated area 4 can serve as a main functional area in which sample collection, preparation, amplification, etc. can be carried out.

According to 3 the buffer unit 3 can be defined by the inflatable film structure 1 and separate the clean room 2 from the heavily soiled area 4. The buffer unit 3 has an inner opening and closing door 33 configured to airtightly separate or connect the buffer unit 3 to the clean area 2 and the heavy pollution area 4 . Thereby physical isolation from the clean room 2, the buffer unit 3 and the heavy pollution area 4 can be achieved.

The input device-integrated module 5 is arranged at one end of the function room 19 and has at least one entrance door 51 which is airtightly separated from or connected to the clean room 2 as shown in FIG 1 until 3 shown.

In a specific embodiment, entrance door 51 may be a single layer door. When the entrance door 51 is opened, the clean room 2 can communicate with the outside world.

In other optional embodiments, the entrance door 51 may be a double panel door. The double-layer door consists of an inner door and an outer door. The front door 51 can be used as an intelligent interactive front door z. B. optical interactive entrance door can be designed to enable intelligent locking of the inner and outer doors. That is, the inner and outer doors are set so that they cannot be opened at the same time for isolating the clean room 2 from the outside world. For example, when the inner door of the entrance door 51 is opened and the outer door is closed, the interior of the entrance door 51 is connected to the clean room 2 and isolated from the outside. When the outer door of the entrance door 51 is opened and the inner door is closed, the interior of the entrance door 51 is communicated with the outside and isolated from the clean room 2 .

As in 1 until 3 shown, the output device-integrated module 6 is arranged at the other end of the functional space 19 . The output device-integrated module 6 has at least one waste disposal case 61. The waste occurring in the functional space 19 can be sterilized and routed from the waste disposal case 61 to the outside.

At least one of the input-device-integrated module 5 and the output-device-inte The integrated module 6 also includes a two-way heat exchanger fresh air fan with a filter device, which is set up to supply air to the functional space 19 or to suck air out of the functional space 19 . That is, the two-way heat exchanger fresh air blower can fulfill the suction and gas conveying function. Several two-way heat exchanger fresh air blowers can be provided, and the operating modes can also be combined in a variety of ways. For example, some two-way heat exchanger fresh air blowers exhaust the air from the functional space 19 while the other two-way heat exchanger fresh air blowers supply the air to the functional space 19 . Alternatively, all two-way heat exchanger fresh air blowers lead the air to the functional space 19 simultaneously for a certain period of time, and then suck the air out of the functional space 19 at the same time. The air supply and the air extraction can alternate.

The directed air flow can be formed in the functional space 19 by the air supply and extraction from the two-way heat exchanger fresh air fan. Because the two-way heat exchanger fresh air blower is equipped with a filter device, the air can be efficiently filtered at both the inlet and outlet, avoiding dust, particles and other substances in the outside air into the functional room 19, as well as the virus in the functional room 19 to the outside world will. This ensures the higher application safety of the membrane-structured virus detection laboratory.

With the help of the two-way heat exchanger fresh air blower, heavily polluted area 4 can be a negative pressure environment. For example, when the amount of air that the two-way heat-exchanger fresh air blower supplies to the heavily polluted area 4 is smaller than the amount of air that is exhausted from the heavily polluted area 4, the heavily polluted area 4 is a negative pressure environment. By setting the heavy pollution area 4 in the negative pressure environment, pathogenic microorganisms in the heavy pollution area 4 can be effectively prevented from spreading to the external environment.

In some optional embodiments, it may also be possible that the amount of air that the two-way heat exchanger fresh air blower supplies to the heavily contaminated area 4 is greater than the amount of air that is sucked out of the heavily contaminated area 4 . In this case, the heavily soiled area 4 is an overpressure environment.

Optionally, the filter device can be a multi-layer high-efficiency particulate air filter (HEPA). The HEPA high efficiency filter, as a filter that meets HEPA standards, is 99.7% effective in filtering substances of 0.1 microns and 0.3 microns. HEPA screen lets air through but not small particles. It is the most effective filter for pollutants such as smoke, dust and bacteria by being able to remove particles with a diameter of 0.3 microns (1/200 hair diameter) by more than 99.97%. HEPA can be divided into five types by material: PP filter paper, glass fiber, PP-PET filter paper, melt-sprayed polyester non-woven fabrics and melt-sprayed fiberglass. HEPA has the characteristics of great wind resistance and dust capacity, high filtration accuracy. Besides, it can be processed into a variety of sizes and shapes according to customer requirements, suitable for different models.

In the membrane-structured virus detection laboratory according to an embodiment of the present utility model, a modular structure of the membrane-structured virus detection laboratory can be achieved by arranging the input device-integrated module 5 and the output device-integrated module 6 . The administration of the devices can advantageously be centralized by integrating all the input devices into the module 5 integrated with input devices and all the output devices in the module 6 integrated into output devices. Therefore, the laboratory can be simple and beautiful. In addition, the inflatable film structure 1 can form the house body or tubular body by inflation, which can advantageously achieve the rapid construction of the membrane-structured virus detection laboratory. This significantly reduces the time required from the construction to the preliminary use of the membrane-structured virus detection laboratory, so that the membrane-structured virus detection laboratory can be put into operation as quickly as possible. In addition, heavy pollution area 4 negative pressure environment is conducive to ensure safety during virus detection, so that the laboratory meets the relevant biosafety level specifications.

In some embodiments, the heavy pollution area 4, the buffer unit 3 and the clean room 2 are all negative pressure environments. In other words, the negative pressure environment in the functional room 19 allows the clean room 2 to connect to the outside world with the entrance door 51 open. As a result, the air only flows from the outside to the clean room 2 but not from the clean room 2 to the outside. In this way, the security of the membrane-structured virus detection laboratory can be improved.

• Reinraum 2> Puffereinheit 3 > Starkverschmutzungsbereich 4. Das heißt, der Reinraum 2 hat den schwächsten Unterdruck und der Starkverschmutzungsbereich 4 hat den stärksten Unterdruck. Wenn also der Reinraum 2 mit der Puffereinheit 3 verbunden ist, strömt die Luft nur vom Reinraum 2 mit dem schwachen Unterdruck zur Puffereinheit 3, nicht von der Puffereinheit 3 zum Reinraum 2,
• wodurch der Luftstrom von der Puffereinheit 3 zum Reinraum 2 vermieden wird, was zu einer Kontamination des Reinraums 2 führt.
• Wenn also die Puffereinheit 3 mit dem Starkverschmutzungsbereich 4 verbunden ist, strömt die Luft nur von der Puffereinheit 3 mit dem schwachen Unterdruck zum Starkverschmutzungsbereich 4, nicht vom Starkverschmutzungsbereich 4 zur Puffereinheit 3, wodurch Durchflusses von der unsauberen Luft im Starkverschmutzungsbereich 4 zur Puffereinheit 3 vermieden wird,
• was zur Kontamination der Puffereinheit 3 führt. Der stärkste Unterdruck am Starkverschmutzungsbereich 4 kann der die Ausbreitung pathogener Mikroorganismen aus dem Starkverschmutzungsbereich 4 wirksam verhindern, sodass die Sicherheit des membranstrukturierten Virenerkennungslabors weiter zu verbessert werden kann.

An air pressure difference is formed by the clean room 2, the buffer unit 3 and the heavy pollution area 4. The clean room 2, the buffer unit 3 and the heavily soiled area 4 have a pressure ratio:

• Clean room 2 > buffer unit 3 > heavily contaminated area 4. That is, the clean room 2 has the weakest negative pressure and the heavily contaminated area 4 has the strongest negative pressure. So when the clean room 2 is connected to the buffer unit 3, the air flows only from the clean room 2 with the weak negative pressure to the buffer unit 3, not from the buffer unit 3 to the clean room 2,
• whereby the flow of air from the buffer unit 3 to the clean room 2 is avoided, resulting in contamination of the clean room 2.
• Therefore, when the buffer unit 3 is connected to the heavily polluted area 4, the air flows only from the weak negative pressure buffer unit 3 to the heavily polluted area 4, not from the heavily polluted area 4 to the buffer unit 3, thereby avoiding flow from the dirty air in the heavily polluted area 4 to the buffer unit 3 ,
• which leads to the contamination of the buffer unit 3. The strongest negative pressure at the heavily contaminated area 4 can effectively prevent the spread of pathogenic microorganisms from the heavily contaminated area 4, so that the safety of the membrane-structured virus detection laboratory can be further improved.

As in 2 shown, the membrane-structured virus detection laboratory may further include at least one air column tube 71 . One end of the air column tube 71 extends into the functional space 19, and the other end of the air column tube 71 is connected to the corresponding two-way heat exchanger fresh air blower.

Further, on the air column tube 71, a first air duct opening communicating with the clean room 2, a second air duct opening communicating with the buffer unit 3, and a third air duct opening communicating with the heavy pollution area are defined. In the working of the two-way heat exchanger fresh air blower, the first air duct opening, the second air duct opening and the third air duct opening on the air column tube 71 can transfer the air to the clean room 2, the buffer unit 3 and the heavy pollution area 4, respectively, or out of the clean room 2, the buffer unit, respectively 3 and the heavily soiled area 4.

An air column tube 71 corresponds to a two-way heat-exchange fresh air blower.

In the present utility model, the terms "first", "second" and "third" are used for descriptive purposes only and should not be construed to indicate or imply a relative meaning or to imply the number of technical features stated. Thus, the features defined by "first," "second," and "third" may explicitly or implicitly include one or more of the features. In the description of the present utility model, "several" means at least two, e.g. B. two, three, etc., unless specifically defined otherwise.

in the in 1 until 2 In the embodiment shown, the two-way heat-exchanger fresh air blower includes an inlet-side two-way heat-exchanger fresh air blower 52 belonging to the input-device-integrated module 5 and an outlet-side two-way heat-exchanger fresh-air blower 62 belonging to the output-device-integrated module 6. The inlet-side two-way heat-exchanger fresh air blower 52 is connected to the inlet-side air column duct 71, and the outlet-side two-way heat-exchanger fresh air blower 62 is connected to the outlet-side air column duct 71, as in FIG 2 shown.

In some embodiments, the inlet-side two-way heat exchanger fresh-air fan 52 can be designed as a fresh-air fan for supplying air to the functional space 19, while the outlet-side two-way heat-exchanger fresh-air fan 62 can be designed as a fresh-air fan for extracting air from the functional space 19. A plurality of inlet-side two-way heat-exchanger fresh air fans 52 and a plurality of outlet-side two-way heat-exchanger fresh air fans 62 may be provided to improve the efficiency of air supply and exhaust.

Further, at least one of the input device-integrated module 5 and the output device-integrated module 6 includes an air conditioning outdoor unit. An air conditioning indoor unit 72 is provided in the functional space 19 . The air conditioner for adjusting the temperature in the function room 19 consists of the air conditioning outdoor unit and the air conditioning indoor unit 72.

Specifically, the air conditioning outdoor unit includes an inlet-side air-conditioning outdoor unit 53 belonging to the inlet-unit-integrated module 5 and an outlet-side air-conditioning outdoor unit 63 belonging to the outlet-unit-in integrated module 6 belongs, as in 1 until 2 shown.

Further, the input equipment-integrated module 5 includes an input equipment frame 54 on which the input-side outdoor air conditioner unit 53 and the input-side two-way heat-exchanger fresh air blower 52 are set.

As in 2 shown, the input device-integrated module 5 also includes a waste water tank 55, which is placed on the input device frame 54. The inlet equipment frame 54 can be constructed into a multi-layered bracket, whereby the inlet-side outdoor air conditioning unit 53, the inlet-side two-way heat-exchanger fresh air blower 52, and the waste water tank 55 can be arranged at different levels. For example, the two-way heat-exchanger entrance-side fresh air blower 52 can be arranged on the uppermost level, so that the two-way heat-exchanger entrance-side fresh air blower 52 can be connected to the air column pipe 71 smoothly. At the same time, sewage tank 55 can be placed at the lowest level due to its heavy weight, for example, to ensure better placement stability. The arrangement at different levels is also conducive to saving space and realizing the integrated layout of the laboratory.

Optionally, the entrance door 51 is designed as an intelligent interactive entrance door. The entrance door 51 can be opened and closed without contact. Therefore, the experimenter can enter or exit the entrance door 51 without contacting the entrance door 51. In some optional embodiments, the front door 51 can be an optically interactive front door such that the front door 51 can be turned on or off using a cell phone flash or flash ring. In other optional embodiments, front door 51 may also be a front door with voice interaction, allowing front door 51 to be turned on or off with voice instructions. This ensures that the experimenter can also control the entrance door 51 without contact if the experimenter is wearing protective clothing and no face scan is taking place.

As in 2 1, the outlet equipment-integrated module 6 further includes an outlet equipment stand 64 on which a garbage disposal case 61, the outlet-side air conditioning outdoor unit 63, and the outlet-side two-way heat-exchanger fresh air blower 62 are set. The exit rack 64 can be constructed as a multi-layer mount. Thereby, the garbage disposal case 61, the outlet-side air-conditioning outdoor unit 63, and the outlet-side two-way heat-exchanger fresh air blower 6 can be arranged at different levels. For example, the two-way heat-exchanger exit-side fresh air blower 62 can be arranged on the uppermost level, so that the heat-exchanger two-way exit-side fresh air blower 62 can be connected to the air column pipe 71 smoothly. The garbage disposal case 61 can be arranged at the lowest level due to its high frequency of utilization, so that the garbage flowing through the garbage disposal case 61 does not affect the outlet-side outdoor air conditioning unit 63 and the two-way heat exchanger fresh air blower 62. The arrangement at different levels is also conducive to the Space saving and the realization of the integrated design of the laboratory.

As in 2 , 3 and 8th shown, the output device-integrated module 6 also includes an escape door 65 which is airtightly separated from or connected to the heavily soiled area 4 . In the event of a dangerous situation within the heavily polluted area 4, the experimenters could quickly escape through escape door 65. The escape flow line is in the B line in 8th shown.

In some embodiments, a smoke detection system is arranged in at least one of the clean room 2 , the buffer unit 3 and the heavily polluted area 4 . For example, the smoke detection system can be placed within the heavily polluted area 4 . It is also conceivable that the smoke alarm system is arranged in each of the clean room 2 , the buffer unit 3 and the heavily soiled area 4 . The smoke alarm system can warn in the event of a fire in the laboratory to improve the fireproof property of the membrane-structured virus detection laboratory and guarantee the safety during the use of the membrane-structured virus detection laboratory.

In some embodiments, a powder extinguisher is arranged in at least one of the clean room 2 , the buffer unit 3 and the heavy pollution area 4 . For example, the powder extinguisher can be placed inside the heavy pollution area 4 . It is also conceivable that the powder extinguisher is arranged in each of the clean room 2 , the buffer unit 3 and the heavy pollution area 4 . The powder extinguisher can extinguish small fires and prevent them from spreading, thereby improving the fireproof property of the membrane-structured virus detection laboratory and guaranteeing the safety during use of the membrane-structured virus detection laboratory.

As in 3 As shown, within the heavy pollution area 4 there are provided one or more air disinfection means 73 comprising one or more of a plasma disinfector, an ultraviolet ozone generator, a dry mist hydrogen peroxide sterilizer. The air disinfection device 73 can reduce a harmful air content in the heavy pollution area 4 to ensure the safety of the experimenters in the heavy pollution area 4 . The air sanitizer 73 may be an ultraviolet vehicle that allows the air sanitizer to move freely within the heavy pollution area 4 . In this way, the disinfection of air in different areas can be facilitated.

As in 3 As shown, the buffer unit 3 comprises a first changing room 31 and a second changing room 32 which are independent of each other and have an inner opening and closing door 33, respectively.

As in 3 and 8th shown, an inlet duct is defined by the entrance door 51, the inner opening and closing door 33 between the first changing room 31 and the clean room 2, and the inner opening and closing door 33 between the first changing room 31 and the heavy pollution area 4, and an outlet duct is from the inner opening and closing door 33 between the second changing room 32 and the heavy pollution area 4, the inner opening and closing door 33 between the second changing room 32 and the clean room 2 and the entrance door 51 is defined. The experimenter's personnel flow in the membrane-structured virus detection laboratory can be seen in the A-line in 8th being represented. That is, the experimenter enters the heavy pollution area 4 through the entrance door 51, the inner opening and closing door 33 between the first changing room 31 and the clean room 2, and the inner opening and closing door 33 between the first changing room 31 and the heavy pollution area 4, and the Experimenter exits the heavy pollution area 4 through the inner opening and closing door 33 between the second changing room 32 and the heavy pollution area 4, the inner opening and closing door 33 between the second changing room 32 and the clean room 2, and the entrance door 51.

The first changing room 31 is located in the inlet channel, so that the experimenter can replace non-toxic protective clothing in the first changing room 31 . The second changing room 32 is located in the outflow channel, so that the experimenter can remove the contaminated protective clothing in the second changing room 32 .

Optionally, the interior opening and closing door 33 is opened and closed using any one or a combination of zippers, magnetic attraction, adhesives, hooks and buckles. These openings and closings are easy and convenient, allowing an experimenter to open or close the inner opening and closing door 33 quickly. In this way, the connection time between the buffer unit 3 and the clean room 2 and between the buffer unit 3 and the heavy pollution area 4 can be shortened.

As in 2 shown, a lighting strip 74 is arranged in the functional space 19, which is fastened to the inflatable film structure 1 by means of a Velcro fastener and/or bandage. in the in 2 In the embodiment shown, the lighting band 74 is constructed as a curved lamp belt that extends along the inner surface of the inflatable sheet structure 1 to improve the aesthetics of the lighting band 74. In some embodiments (not shown), the lighting strip 74 can also be formed into other shapes, e.g. For example, a linear lamp belt could be formed and extended along the length of the membrane-structured virus identification laboratory to increase the length of the illumination band 74 and expand the exposure area.

In some embodiments, the inflatable film structure 1 includes an inflatable dome structure and an inflatable isolation structure. The functional space 19 is defined by the inflated dome structure. The buffer unit 3 is defined by the inflated insulation structure. The air film space 17 within the inflatable isolation structure and the air film space 17 within the inflatable dome structure may be interconnected or independent of each other.

In the embodiment shown in 1 and 4 As shown, the inflatable dome structure includes a plurality of closely spaced arcuate inflatable rings 14. The inflatable ring 14 has an internal positive pressure air film space 17. In other words, the air film space 17 within the inflatable ring 14 is a positive pressure environment, thereby ensuring that the inflatable Ring 14 has a greater hardness and the outside of the functional space 19 can support. In this way, the spatial form of the functional space 19 can remain.

As in 4 As shown, the inflatable ring 14 comprises an inner sheet 11 and an outer sheet 12. The air film space 17 is located between the inner membrane 11 and the outer membrane 12. Preferably, the air film spaces 17 in the various inflatable rings 14 are independent from each other. As a result, if one of the inflatable rings 14 breaks, the other inflatable rings 14 can continue to be used without the entire inflatable film structure 1 having to be replaced immediately. In addition, the damaged inflatable ring 14 can be patched and reused. Of course, the air film spaces 17 of adjacent inflatable rings 14 may be interconnected.

Furthermore, a single-layer film 13 covers the inside of the inflatable ring 14, i.e. the single-layer film 13 covers the inflatable ring 14 from the inside. In addition, the single-layer sheet 13 has a flat inner surface of the single-layer sheet 13 and no gap between the two adjacent inflatable rings 14. As a result, the top of the functional space 19 is flat and avoids the unsightly gap between the two adjacent inflatable rings 14 being exposed. At the same time, the single-layer foil 13 offers a better sealing property for the inflatable dome structure.

in the in 5 (a) In the embodiment shown, the inflatable dome structure includes a support frame 15 on its outside and a single-layer film 13 on its inside. A positive air film space 17 is formed between the single layer film 13 and the support frame 15 . The support frame 15 may have multiple sections. The single ply film 13 touches the edges of each section from the support frame and separates from the central portion of each section. Gas is injected between the monolayer film 13 and the corresponding section of support frame to enable the properties of the inflatable dome structure such as heat retention and insulation. At the same time, a plurality of air film spaces 17 are formed between the monolayer film 13 and the various sections of the support frame. If one of the air film spaces 17 is damaged, the other air film spaces 17 can also be used normally.

in the in 5(b) In the embodiment shown, the inflatable dome structure comprises a support frame 15 on its outside and double-layer foils on its inside. The double layer foils have a positive air film space 17 inside. The support frame 15 is confined to the outside of the double-layered films and limits the position of the double-layered films.

The dual layer films include an inner film 11 and an outer film 12. The air film space 17 is located between the inner membrane 11 and the outer membrane 12. The support frame 15 may have multiple sections. The outer sheet 12 of the double layer sheets contacts each section of the support frame. The double-layer films can add properties such as heat retention and insulation to the inflatable dome structure. Simultaneously, several air film spaces 17 can be formed, which are separated from each other. If one of the air film spaces 17 is damaged, the other air film spaces 17 can also be used normally.

The supporting frame 15 can be a steel frame or a load-bearing frame construction such as a plastic frame or composite frame, etc.

In the embodiment shown in 6 and 7 As shown, the inflatable dome structure includes a support air column frame 16 consisting of a plurality of support air columns 161 with positive pressure air film space 17 inside. The outside of the supporting air column frame 16 is covered with a single-layer film 13 or double-layer films with positive air film space 17 . The supporting air column frame 16 has a function of supporting the single-layer film 13 or the double-layer films. By covering the single-layer film 13 or double-layer films on the outside of the supporting air column frame 16, the inflatable dome structure can have the properties such as heat retention, insulation and good sealing property. In some embodiments, there are multiple air columns 161. If one of the air columns 161 is damaged, the other air columns 161 can also be used normally.

The inner film 11, the outer film 12, the single-layer film 13 and the supporting air column 161 can be made with the same material.

In relation to 1 , 3 until 5 For example, the inflatable film structure 1 comprises an air film space 17, a film structure fill opening and a film structure air outlet 18. A blower is connected to the film structure fill opening and arranged to blow air into the air film space 17. An air inlet at the film structure fill opening is larger than an air outlet at the film structure air outlet 18, so that the air film space 17 is a positive air film space. The fan can be on the in 2 shown fan frame 56 can be mounted, which can be firmly connected to the input device frame 54. Therefore, the fan frame 56 can become a part of the input device-integrated module 5 .

The materials of the inflatable sheet structure 1 mainly include fiberglass fabric, plastic sheeting, metal mesh, etc., preferably fiberglass fabric. The surface of the inflatable sheet structure 1 can be coated with coatings such as Teflon to improve its durability and fire resistance. In addition, the inflatable film structure 1 can be sprayed with architectural coatings on its inside after inflation to improve stability and physical properties to improve protective properties and increase insulation strength, etc. For example, a waterproof polyurethane coating can be sprayed on the inside of the inflatable film structure 1 to improve waterproofing.

The inflatable sheet structure 1 also has better toughness to avoid easy breakage during installation or use. In addition, the inflatable film structure 1 can be transparent or dark with masking effect to meet different needs. Further, depending on the length of the outbreak incubation period or the isolation period, or depending on the complexity of the terrain, the inflatable sheets having different thicknesses are flexibly selected as the inflatable sheet structure 1 .

In some non-illustrated embodiments, the inflatable film structure 1 comprises an inner film and an outer film. An air film space is formed between the inner sheet and the outer sheet. The materials of the inner and outer foils can be welded, glued and sewn. In some optional embodiments, the air film space can be a fully sealed cavity. In other optional embodiments, the air film space can be divided into multiple continuous and sealed cavities. If one of these cavities is damaged in the process, the other cavities can continue to be used without the entire inflatable film structure 1 having to be replaced immediately. In addition, the damaged cavities can be repaired for further use. The outer foil corresponding to each cavity is provided with an opening for pre-inflation. Simply put, airtight protection and durability can be improved by forming the inflatable sheet structure 1 as double-layer sheets.

As in 1 As shown, a foil structure air vent 18 is provided on the inflatable ring 14 . In one embodiment, each inflatable ring 14 includes a foil structure air vent 18 . In another embodiment, multiple inflatable rings share a same foil structure air vent 18.

According to some embodiments of the present utility model, the heavily soiled area 4 is equipped with a humidifier to meet moisture demand. The humidifier ensures that the humidity in the heavily soiled area 4 meets the humidity requirements, i. H. that the humidity in the heavy pollution area 4 is within the range required by the technical specification.

According to some embodiments of the present utility model, one or more skylights for lighting or ventilation are provided on the upper side of the heavily soiled area 4 . An inboard disposable filter device is located on the skylight. Only outside air may enter the heavily soiled area 4 through the disposable filter device and the air inside the heavily soiled area 4 must not escape to the outside. This effectively prevents the virus from escaping within the heavily soiled area 4 . In the practical applications, the lighting and ventilation needs required for the heavy pollution area 4 can be covered by the skylight.

As in 3 As shown, the heavily soiled area 4 has a first transfer port 41 and a second transfer port 42 suitable for setting transfer units.

Optionally, the transfer unit can be a material transfer box and/or a personnel access box 45 . The number of the first transfer port 41 and the number of the second transfer port 42 may be one or more. At the first transfer port 41 and the second transfer port 42, the material transfer box or the personnel access box 45, or both the material transfer box and the personnel access box 45 can be set.

In the in the 3 embodiment shown, the transfer unit is the material transfer box, e.g. a transfer box 43 of intermediate material, and a transfer box 44 of charge material. Samples or reagents can be transferred to the inside of the heavy pollution area area 4 via the material transfer box.

In some non-illustrated embodiments, the transfer unit can be the personnel access box 45 for the experimenters.

In the in the 11 In the embodiment shown, the transfer unit is the material transfer box and the personnel access box 45. The samples or reagents can be transferred via the material transfer box into the interior of the heavily soiled area 4 or taken by the experimenters into the heavily contaminated area 4 through the personnel access box 45.

In some embodiments, the transfer unit and the waste disposal case include 61, respectively an inner door facing the heavy pollution area 4 and an outer door facing outward. The transfer unit and the garbage disposal case 61 use intelligent interaction technology to form an intelligent locking structure through the inner door and the outer door to avoid opening the inner door and the outer door at the same time. In this way, the insulation effect can be achieved on the transfer unit and the garbage disposal case 61 so that the inside of the inner door is not connected to the outside of the outer door. This ensures the safety of the membrane-structured virus detection laboratory. In some optional embodiments, the intelligent interaction technology can be an optical interaction technology. The inner and outer doors are optical interactive doors. The opening or closing commands can be issued to the interior and exterior doors with the help of a mobile phone flash or flash ring. In other optional embodiments, the inner and outer doors may also be voice interaction doors, allowing the inner and outer doors to be turned on or off with voice instructions. This ensures that the experimenter can also control the transfer unit and the waste disposal case 61 without contact if the experimenter is wearing protective clothing and a face scan cannot be carried out.

In some embodiments, the inflatable sheet structure 1 can be folded and stored by suction. Because of the high volume compression ratio of the inflatable sheet structure 1, many folded inflatable sheet structure 1 can be stored in a limited space and transported at one time, facilitating the rapid construction of the laboratory. In the event of an outbreak, the membrane-structured virus detection laboratory according to the present utility model can be put into operation immediately as a temporary building in the vicinity of an outbreak site. After the peak period of the outbreak, through the suction of the membrane-structured virus detection laboratory and the disinfection of the inflatable film structure 1, the membrane-structured virus detection laboratory can be transported to a new place and rebuilt.

By one or a combination of spraying the building materials, pouring concrete and covering the vegetation on the outer surface of the inflatable sheet structure 1, the inflatable sheet structure can be upgraded in terms of its properties or converted into a permanent building.

In relation to 3 , 8th until 11 according to a second aspect of the present utility model, the biosafety laboratory comprises a plurality of membrane-structured virus detection laboratories according to the first aspect of the present utility model. The second transfer port 42 of a membrane-structured virus detection laboratory and the first transfer port 41 of an adjacent membrane-structured virus detection laboratory are aligned with one another and connected to one another via the transfer unit.

In an embodiment defined in 3 , 8th are you 10 shown, there are two membrane-structured virus detection laboratories. The second transfer port 42 of a first membrane-structured virus detection laboratory 10 and the first transfer port 41 of a second membrane-structured virus detection laboratory 20 are aligned with one another and connected to one another via the transfer unit. in the in 3 In the embodiment shown, the transfer unit between the second transfer port 42 of the first membrane-structured virus detection laboratory 10 and the first transfer port 41 of the second membrane-structured virus detection laboratory 20 is a transfer box 43 of the intermediate material. The intermediate material transfer box 43 has a smaller size to minimize the distance between the two membrane-structured virus detection laboratories. This reduces the footprint of biosafety labs and makes it easy to place multiple biosafety labs in a limited space, further increasing day-to-day detection efficiency.

The heavily soiled area 4 of the first membrane-structured virus detection laboratory 10 is a sample acceptance and preparation area for accepting the samples and with highly integrated sample preparation. The heavily soiled area 4 of the second membrane-structured virus detection laboratory 20 is an amplification area. in the in 3 In the embodiment shown, nucleic acid samples prepared in the sample collection and preparation area can be transferred to the amplification area via the intermediate material transfer box 43 without the experimenters going from the sample collection and preparation area to the amplification area.

The first transfer port 41 of the first membrane-structured virus detection laboratory 10 is a first sample import. The second transfer port 42 of the second membrane-structured virus detection laboratory 20 is a second sample import. in the in 3 shown embodiment, the transfer units at the first sample import and at the second sample import are a transfer box 44 of feedstock.

In 10 shows the material flow lines of the biosafety laboratory. The samples included in the pro be removed designation area can be transferred to the first sample import in the first membrane-structured virus detection laboratory 10, such. B. Flow line D1 in 10 shown. The reagents can be transferred to the second membrane-structured virus detection laboratory 20 via the second sample import, e.g. B. Flow line D2 in 10 shown. The material flow line at intermediate material transfer box 43 is shown as flow line D3 in 10 shown.

The transfer box 44 of action material is a disinfection transfer box to improve safety.

In relation to 3 A sample inactivation zone, a sample unpacking and information verification zone, a sample tube transfer zone and a sample preparation zone are provided in the heavy pollution area 4 of the first membrane-structured virus detection laboratory 10 to fulfill the sample acceptance and preparation process.

Also provided at the sample inactivation zone is a drying box 101 in which the sample is inactivated. In particular, at the sample unpacking and information verification zone, a first biological safety cabinet 102 is provided where samples are unpacked and information is verified. In particular, at the sample tube transfer zone, a second biological safety cabinet 103 is provided in which a sample tube is transferred. In particular, a sample nucleic acid extractor 104 for automatic sampling of the nucleic acid is provided at the sample preparation zone.

A centrifuge 81, a refrigerator 82, a printer 83, an oscillator 84 or a combination thereof is optionally provided in the first membrane-structured virus detection laboratory 10. The centrifuge 81 can be a plate centrifuge, palm-top centrifuge, high-speed centrifuge, or a combination thereof.

Optionally, the drying box 101 is located next to the first sample import, so that the samples from the first sample import can be inactivated in the nearby drying box 101. As a result, the residence time of the inactivated samples in the first membrane-structured virus detection laboratory 10 is reduced.

A nucleic acid amplifier 201 for carrying out the sample amplification process is provided in the heavily soiled area 4 of the second membrane-structured virus detection laboratory 20 . The nucleic acid amplifier 201 can be a fluorescent quantitative PCR instrument for exponential amplification of nucleic acids.

A centrifuge 81, a refrigerator 82, a printer 83, an oscillator 84 or a combination thereof is optionally provided in the second membrane-structured virus detection laboratory 10. The centrifuge 81 can be a plate centrifuge, palm-top centrifuge, high-speed centrifuge, or a combination thereof.

The centrifuge 81 can be used for the centrifugal operation of the samples. The refrigerator 82 can cool the samples. The oscillator 84 can oscillate the samples. The printer 83 can be used to print sample information, labels, etc.

As in 3 and 9 As shown, the dry box 101, the first biological safety cabinet 102, the second biological safety cabinet 103, the sample nucleic acid extractor 104 and the nucleic acid amplifier 201 are used in sequence.

Further, an autoclave 85 for sterilizing medical waste may be further provided in the heavy pollution area 4 of each of the first membrane-structured virus detection laboratory 10 and the second membrane-structured virus detection laboratory 20 . The sterilized waste is then delivered to the external receiving facility via the appropriate waste disposal case 61 . This ensures that the waste disposed of from the biosafety laboratory is sterilized and secondary pollution of the environment is prevented. The waste flow lines on the waste disposal case 61 are shown as flow line E1 and flow line E2 in 10 shown.

In the biosafety laboratory according to the second aspect of the present utility model, the sample acceptance and preparation area is separated from the amplification area via the transfer unit. This advantageously improves the reliability of the biosafety laboratory. Once a leak of amplified nucleic acids occurs in the amplification area, the leaking nucleic acids are prevented from entering the sample collection and preparation area.

in the in 11 In the embodiment shown, at least one first auxiliary laboratory is provided to support the sample acceptance and preparation process on the side of the first membrane-structured virus detection laboratory 10 facing away from the second membrane-structured virus detection laboratory 20, e.g. B. Laboratory 30.

At least one second auxiliary laboratory to support the amplification process is provided on the side of the second membrane-structured virus detection laboratory 20 facing away from the first membrane-structured virus detection laboratory 10, e.g. B. Labor 40 and Labor 50.

The first auxiliary laboratory 30 and the second auxiliary laboratory 40, 50 both are the membrane-structured virus detection laboratory. Between any two adjacent membrane-structured virus detection laboratories, the circulation of materials or people can be achieved by means of intermediate material transfer box 43 and/or personnel access box 45 .

Between the first membrane-structured virus detection laboratory 10 and the second membrane-structured virus detection laboratory 20, only the intermediate material transfer box 43 and no personnel access box 45 may be provided. As a result, the movement of the experimenters between the amplification area of the second membrane-structured virus detection laboratory 20 and the sample acceptance and preparation area of the first membrane-structured virus detection laboratory 10 can be reduced.

The intermediate material transfer box 43 and the personnel access box 45 can be between the first membrane-structured virus detection laboratory 10 and the first auxiliary laboratory 30. The intermediate material transfer box 43 and the personnel access box 45 can be between the second membrane-structured virus detection laboratory 20 and the second auxiliary laboratory 40, 50.

A ground-covering virus detection laboratory according to a third aspect of the present utility model includes the membrane-structured virus detection laboratory according to the first aspect of the present utility model. By one or a combination of spraying the building materials, pouring concrete, and covering the vegetation on the outer surface of the inflatable sheet structure 1, the membrane-structured virus detection laboratory can be converted into a permanent and ground-covering building. The membrane-structured virus detection laboratory is a single laboratory. The ground-covering virus detection laboratory that includes this single membrane-structured virus detection laboratory is also a single laboratory.

A ground covering virus detection laboratory according to a fourth aspect of the present utility model comprises the biosafety laboratory according to the second aspect of the present utility model. Through one or a combination of spraying the construction materials, pouring concrete, and covering the vegetation on the outer surface of the inflatable sheet structure, the biosecurity laboratory can be converted into a permanent and ground-covering building. The biosafety laboratory includes several laboratories. The ground covering virus detection lab that includes this biosecurity lab also includes multiple labs.

According to some embodiments of the present utility model, the outer surface of the inflatable sheet structure 1 may be sprayed or sprayed with polyurethane, steel fiber reinforced concrete, EPS gypsum, or a combination thereof. Of course, other spray coating materials not mentioned in the present utility model can also be used to spray the outer surface of the inflatable sheet structure 1.

In addition, the safety of the membrane-structured virus identification laboratory, the biosafety laboratory, the ground-cover virus identification laboratory can be advantageously increased by strictly separating the flows of people (A, B), the flows of materials (D1, D2, D3) and the flows of waste (E1, E2).

In the description of the present utility model, the terms "an embodiment", "some embodiments", "examples", "specific examples" or "some examples" etc. mean that the specific features, structures, materials or properties associated with described in the embodiment or example are included in at least one embodiment or example of the present utility model. In this description, the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Also, those skilled in the art may combine different embodiments or examples described in this specification.

Although the embodiments of the present utility model have been illustrated and described above, it should be understood that the above-mentioned embodiments are exemplary and should not be construed as limiting the present disclosure. Those skilled in the art can make changes, modifications, substitutions, and variations to the foregoing embodiments within the present disclosure.

Claims (46)

Foil structured virus detection laboratory, comprising: - an inflatable film structure (1) inflatable to form a house body or a tubular body, wherein the inflatable film structure (1) upon inflation forms a functional space (19), therein a clean room (2), one or more auxiliary functional areas serving buffer units (3) and a heavily soiled area (4) serving as the main functional area are provided, wherein the buffer unit (3), which is defined by the inflatable film structure (1), separates the clean room (2) from the heavily soiled area (4) and an inner an opening and closing door (33) configured to airtightly separate or connect the buffer unit (3) from the clean area (2) and the heavy pollution area (4); - an input device-integrated module (5) which is arranged at one end of the functional space (19) and has at least one input door (51) which is airtightly separated from or connected to the clean room (2); and - an output device-integrated module (6) which is arranged at the other end of the functional space (19) and has at least one garbage disposal case (61); wherein at least one of the input device-integrated module (5) and the output device-integrated module (6) further comprises a two-way heat exchanger fresh air blower with a filter device, which is arranged to supply air to the functional space (19) or from the functional space (19) suck off, and with which the heavily soiled area (4) is converted into a negative pressure environment. Foil structured virus detection laboratory claim 1 , characterized in that the buffer unit (3) and the clean room (2) are both in negative pressure environments, and that the clean room (2), the buffer unit (3) and the heavy pollution area (4) satisfy a pressure ratio: clean room (2) > buffer unit (3) > Heavy pollution area (4) . Foil structured virus detection laboratory claim 2 , further comprising at least one air column tube (71), one end of the air column tube (71) extending into the functional space (19), and the other end of the air column tube (71) being connected to the corresponding two-way heat exchanger fresh air blower. Foil structured virus detection laboratory claim 3 , characterized in that a first air duct opening communicating with the clean room (2), a second air duct opening communicating with the buffer unit (3) and a third air duct opening communicating with the heavy pollution area (4) on the air column pipe (71) are defined. Foil structured virus detection laboratory claim 1 , characterized in that the two-way heat-exchanger fresh-air blower is an inlet-side two-way heat-exchanger fresh-air blower (52) belonging to the input-device-integrated module (5), and an outlet-side two-way heat-exchanger fresh-air blower (62) belonging to the output-device-integrated Module (6) belongs, includes. Foil structured virus detection laboratory claim 5 , characterized in that at least one of the input device-integrated module (5) and the output device-integrated module (6) further comprises an air conditioning outdoor unit, and that an air conditioning indoor unit (72) is provided in the functional space (19). Foil structured virus detection laboratory claim 6 characterized in that the air conditioning outdoor unit comprises an inlet-side air-conditioning outdoor unit (53) belonging to the inlet-device-integrated module (5) and an outlet-side air-conditioning outdoor unit (63) belonging to the outlet-device-integrated module (6). Foil structured virus detection laboratory claim 7 , characterized in that the input equipment-integrated module (5) further comprises an input equipment frame (54) on which the input-side air conditioner outdoor unit (53) and the input-side two-way heat exchanger fresh air blower (52) are set. Foil structured virus detection laboratory claim 8 , characterized in that the input device-integrated module (5) further comprises a waste water tank (55) which is placed on the input device frame (54). Foil structured virus detection laboratory claim 1 , characterized in that the entrance door (51), which is designed as an intelligent interactive entrance door, can be opened and closed without contact. Foil structured virus detection laboratory claim 7 characterized in that the outlet equipment-integrated module (6) further comprises an outlet equipment frame (64) on which the outlet-side outdoor air conditioner unit (63) and the outlet-side two-way heat-exchanger fresh air blower (62) are set. Foil structured virus detection laboratory claim 1 , characterized in that the output device-integrated module (6) further comprises an escape door (65) which is airtightly separated from or connected to the heavily soiled area (4). Foil structured virus detection laboratory claim 1 , characterized in that a smoke alarm system is arranged in at least one of the clean room (2), the buffer unit (3) and the heavily soiled area (4). Foil structured virus detection laboratory claim 1 , characterized in that a powder extinguisher is arranged in at least one of the clean room (2), the buffer unit (3) and the heavy pollution area (4). Foil structured virus detection laboratory claim 1 characterized in that within the heavy pollution area (4) there are provided one or more air disinfection means (73) comprising one or more of a plasma disinfector, an ultraviolet ozone generator, a dry mist hydrogen peroxide sterilizer. Foil structured virus detection laboratory claim 1 , characterized in that the buffer unit (3) comprises a first changing room (31) and a second changing room (32) which are independent of each other and each have an inner opening and closing door (33). Foil structured virus detection laboratory Claim 16 , characterized in that an inlet duct from the entrance door (51), the inner opening and closing door (33) between the first changing room (31) and the clean room (2) and the inner opening and closing door (33) between the first changing room (31) and the heavy pollution area (4), and that an outlet passage from the inner opening and closing door (33) is defined between the second changing room (32) and the heavy pollution area (4), the inner opening and closing door (33) between the second changing room (32) and the clean room (2) and the entrance door (51). Foil structured virus detection laboratory claim 1 characterized in that the inner opening and closing door (33) is opened and closed by any one or a combination of zippers, magnetic attraction, gluing, hooks and buckles. Foil structured virus detection laboratory claim 1 , characterized in that a lighting band (74) is arranged in the functional space (19) and is attached to the inflatable film structure (1) by means of Velcro and/or binding. Foil structured virus detection laboratory claim 1 , characterized in that the inflatable foil structure (1) comprises an inflatable dome structure and an inflatable isolation structure, the functional space (19) being defined by the inflated dome structure and the buffer unit (3) by the inflated isolation structure. Foil structured virus detection laboratory claim 20 characterized in that the inflatable dome structure comprises a plurality of closely spaced arcuate inflatable rings (14), the inflatable ring (14) having an internal positive pressure air film space (17). Foil structured virus detection laboratory Claim 21 , characterized in that a single-layer film (13) covers an inside of the inflatable ring (14). Foil structured virus detection laboratory claim 20 , characterized in that the inflatable dome structure comprises a supporting frame (15) on its outside and a single-layer foil (13) or double-layer foils on its inside, the single-layer foil (13) being arranged in such a way that an overpressure air film space (17) between the single-layer foil (13) and the support frame (15), and wherein the double-layer foils have a positive air pressure film space (17) inside. Foil structured virus detection laboratory claim 20 , characterized in that the inflatable dome structure comprises a supporting air column frame (16) consisting of several supporting air columns (161) with overpressure air film space (17) inside, the outside of the supporting air column frame (16) being covered with a single-layer film (13) or double-layer films with Überdruckluftfilmraum (17) is covered. Foil structured virus detection laboratory claim 1 , characterized in that the inflatable foil structure (1) comprises an air film space (17), a foil structure filling opening and a foil structure air outlet (18), the foil structure filling opening and the foil structure air outlet (18) being in communication with the air film space (17), a blower with connected to the foil structure filling opening and arranged to blow air into the air film space (17), and that an air inlet at the foil structure filling opening is larger as an air outlet at the foil structure air outlet (18), so that the air film space (17) is a positive pressure air film space. Foil structured virus detection laboratory claim 1 , characterized in that the heavily soiled area (4) is equipped with a humidifier to meet moisture requirements and/or one or more skylights for lighting or ventilation are provided on the top of the heavily soiled area (4), with an inwardly directed disposable filter device on the Skylight is arranged. Foil-structured virus detection laboratory according to one of the Claims 1 until 26 , characterized in that the heavily soiled area (4) has a first transfer port (41) and a second transfer port (42) which are suitable for setting transfer units. Foil structured virus detection laboratory Claim 27 , characterized in that the transfer unit is a transfer box and/or a personnel access box (45). Foil structured virus detection laboratory claim 28 , characterized in that the transfer unit and the waste disposal case (61) each comprise an inner door facing the heavily soiled area (4) and an outer door facing outwards, and that the transfer unit and the garbage disposal case (61) have an intelligent Using interaction technology to form an intelligent locking structure through the inner door and the outer door, avoiding the simultaneous opening of the inner door and the outer door. Foil structured virus detection laboratory claim 28 , characterized in that the inflatable film structure (1) is folded and stored by suction. Foil structured virus detection laboratory claim 28 , characterized in that one or a combination of spraying the building materials, pouring concrete and covering the vegetation on the outer surface of the inflatable film structure (1) improves the properties of the inflatable film structure (1) or converts it into a permanent building . Biosafety laboratory comprising multiple membrane-structured virus detection laboratories according to any of claims 27 until 31 , wherein the second transfer port (42) of a membrane-structured virus detection laboratory and the first transfer port (41) of an adjacent membrane-structured virus detection laboratory are aligned and connected to one another via the transfer unit. biosafety laboratory Claim 32 , characterized in that two membrane-structured virus detection laboratories are provided, the second transfer port (42) of a first membrane-structured virus detection laboratory (10) and the first transfer port (41) of a second membrane-structured virus detection laboratory (20) being aligned with one another and connected to one another via the transfer unit. biosafety laboratory Claim 33 , characterized in that the heavily contaminated area (4) of the first membrane-structured virus detection laboratory (10) is a sample acceptance and preparation area, and that the heavily contaminated area (4) of the second membrane-structured virus detection laboratory (20) is an amplification area. biosafety laboratory Claim 34 , characterized in that the first transfer port (41) of the first membrane-structured virus detection laboratory (10) is a first sample import, and that the second transfer port (42) of the second membrane-structured virus detection laboratory (20) is a second sample import. biosafety laboratory Claim 35 , characterized in that a sample inactivation zone, a sample unpacking and information verification zone, a sample tube transfer zone and a sample preparation zone are provided in the heavy pollution area (4) of the first membrane-structured virus detection laboratory (10) to fulfill the sample acceptance and preparation process. biosafety laboratory Claim 36 , characterized in that a drying box (101) is provided at the sample inactivation zone, in which the sample is inactivated; a first biological safety cabinet (102) is provided at the sample unpacking and information verification zone where samples are unpacked and information is verified; a second biological safety cabinet (103) is provided at the sample tube transfer zone in which a sample tube is transferred; and a sample nucleic acid extractor (104) for automatically sampling the nucleic acid is provided at the sample preparation zone. biosafety laboratory Claim 33 or 37 , characterized in that a centrifuge (81), a refrigerator (82), a printer (83), a Oscillator (84) or a combination thereof is provided in the first membrane-structured virus detection laboratory (10). biosafety laboratory Claim 37 , characterized in that the drying box (101) is arranged next to the first sample import. biosafety laboratory Claim 37 , characterized in that a nucleic acid amplifier (201) for carrying out the sample amplification process is provided in the heavily soiled area (4) of the second membrane-structured virus detection laboratory (20). biosafety laboratory Claim 33 or 40 , characterized in that a centrifuge (81), a refrigerator (82), a printer (83), an oscillator (84) or a combination thereof is provided in the second membrane-structured virus detection laboratory (20). biosafety laboratory Claim 40 , characterized in that the dry box (101), the first biological safety cabinet (102), the second biological safety cabinet (103), the sample nucleic acid extractor (104) and the nucleic acid amplifier (201) are used in sequence. biosafety laboratory Claim 33 characterized in that an autoclave (85) for sterilizing medical waste is further provided in the heavy pollution area (4) of each of the first membrane-structured virus detection laboratory (10) and the second membrane-structured virus detection laboratory (20). biosafety laboratory Claim 34 , characterized in that at least one first auxiliary laboratory to support the sample acceptance and preparation process is provided on the side of the first membrane-structured virus detection laboratory (10) facing away from the second membrane-structured virus detection laboratory (20), and that at least one second auxiliary laboratory to support the amplification process on the dem first membrane-structured virus detection laboratory (10) facing away from the second membrane-structured virus detection laboratory (20) is provided, wherein the first auxiliary laboratory and the second auxiliary laboratory are both the membrane-structured virus detection laboratory. Ground covering virus detection laboratory comprising the membrane structured virus detection laboratory according to any one of Claims 1 until 31 wherein one or a combination of spraying the building materials, pouring concrete and covering the vegetation on the outer surface of the inflatable sheet structure (1) converts the membrane-structured virus detection laboratory into a permanent and ground-covering building. Ground covering virus detection laboratory comprising the membrane structured virus detection laboratory according to any one of Claims 32 until 44 wherein one or a combination of spraying the construction materials, pouring concrete and covering vegetation on the outer surface of the inflatable sheet structure (1) converts the biosecurity laboratory into a permanent and ground covering building.

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