DE2026076C3 - Verfahren zum selektiven Adsorbieren von einem oder mehreren, spezifischen, nicht-viralen Proteinen aus flüssigem Plasma oder Serum - Google Patents

Verfahren zum selektiven Adsorbieren von einem oder mehreren, spezifischen, nicht-viralen Proteinen aus flüssigem Plasma oder Serum

Info

Publication number
DE2026076C3
DE2026076C3 DE2026076A DE2026076A DE2026076C3 DE 2026076 C3 DE2026076 C3 DE 2026076C3 DE 2026076 A DE2026076 A DE 2026076A DE 2026076 A DE2026076 A DE 2026076A DE 2026076 C3 DE2026076 C3 DE 2026076C3
Authority
DE
Germany
Prior art keywords
protein
serum
adsorption
maleic anhydride
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2026076A
Other languages
German (de)
English (en)
Other versions
DE2026076A1 (enExample
DE2026076B2 (de
Inventor
Joseph Louis Melnick
Craig Wallis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of DE2026076A1 publication Critical patent/DE2026076A1/de
Publication of DE2026076B2 publication Critical patent/DE2026076B2/de
Application granted granted Critical
Publication of DE2026076C3 publication Critical patent/DE2026076C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE2026076A 1969-05-29 1970-05-27 Verfahren zum selektiven Adsorbieren von einem oder mehreren, spezifischen, nicht-viralen Proteinen aus flüssigem Plasma oder Serum Expired DE2026076C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82914769A 1969-05-29 1969-05-29

Publications (3)

Publication Number Publication Date
DE2026076A1 DE2026076A1 (enExample) 1970-12-03
DE2026076B2 DE2026076B2 (de) 1979-05-10
DE2026076C3 true DE2026076C3 (de) 1980-01-03

Family

ID=25253656

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2026076A Expired DE2026076C3 (de) 1969-05-29 1970-05-27 Verfahren zum selektiven Adsorbieren von einem oder mehreren, spezifischen, nicht-viralen Proteinen aus flüssigem Plasma oder Serum

Country Status (7)

Country Link
US (1) US3555001A (enExample)
BE (1) BE751088A (enExample)
CA (1) CA925017A (enExample)
DE (1) DE2026076C3 (enExample)
FR (1) FR2048934A5 (enExample)
GB (1) GB1269868A (enExample)
NL (1) NL170419C (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1412274A (en) * 1973-05-29 1975-11-05 Bio Rad Laboratories Radioactive determination of serum thyroxine
NL7708005A (nl) * 1976-07-22 1978-01-24 Monsanto Co Werkwijze voor de bereiding van serumalbumine.
US4075197A (en) * 1976-09-20 1978-02-21 Monsanto Company Serum albumin production
US4055469A (en) * 1976-12-10 1977-10-25 Eastman Kodak Company Purification of microbial enzyme extracts using synthetic polyelectrolytes
ES471858A1 (es) * 1977-07-25 1979-02-01 Monsanto Co Un metodo para separar el factor especifico de coagulacion de la sangre de una mezcla con otras proteinas de la sangre en un medio fluido
US4118554A (en) * 1977-07-25 1978-10-03 Monsanto Company Aggregated polyelectrolytes
US4081432A (en) * 1977-07-25 1978-03-28 Monsanto Company Method of separating a Factor IX preparation from plasma using ethylene-maleic anhydride polymers
JPS5843369B2 (ja) * 1977-09-10 1983-09-27 森六株式会社 血清蛋白質の分画方法
US4397841A (en) * 1982-06-28 1983-08-09 Monsanto Company Production of blood coagulation factor VIII:C
US4471112A (en) * 1982-06-28 1984-09-11 Monsanto Company Heparin polyelectrolyte polymer complex
US4382028A (en) * 1982-07-19 1983-05-03 Monsanto Company Separation of plasma proteins from cell culture systems
US4639513A (en) * 1984-02-02 1987-01-27 Cuno Inc. Intravenously injectable immunoglobulin G (IGG) and method for producing same
US4533496A (en) * 1984-05-08 1985-08-06 Monsanto Company Method of isolating monoclonal antibodies from hybridoma cultures
US5096977A (en) * 1987-08-12 1992-03-17 Atochem North America, Inc. Process for preparing polymer bound UV stabilizers
US4975489A (en) * 1987-08-12 1990-12-04 Atochem North America, Inc. Process for preparing polymer bound hindered amine light stabilizers
US5206378A (en) * 1987-08-12 1993-04-27 Elf Atochem North America, Inc. Hydrazido functionalized 2-(2-hydroxyphenyl)-2h-benzotriazoles
US4981914A (en) * 1987-08-12 1991-01-01 Atochem North America, Inc. Polymer bound UV stabilizers
US4868246A (en) * 1987-08-12 1989-09-19 Pennwalt Corporation Polymer bound UV stabilizers
US5096974A (en) * 1987-08-12 1992-03-17 Atochem North America, Inc. Process for preparing multipurpose polymer bound stabilizers and polymer bound stabilizer produced thereby
US4863999A (en) * 1987-08-12 1989-09-05 Pennwalt Corporation Multipurpose polymer bound stabilizers
US4981915A (en) * 1987-08-12 1991-01-01 Atochem North America, Inc. Multipurpose polymer bound stabilizers
US4866136A (en) * 1987-08-12 1989-09-12 Pennwalt Corporation Process for producing polymer bound hindered amine light stabilizers
US4857596A (en) * 1987-08-12 1989-08-15 Pennwalt Corporation Polymer bound antioxidant stabilizers
US4981917A (en) * 1987-08-12 1991-01-01 Atochem North America, Inc. Process for preparing polymer bound antioxidant stabilizers
US4857595A (en) * 1987-08-12 1989-08-15 Pennwalt Corporation Polymer bound hindered amine light stabilizers
US5037894A (en) * 1988-11-07 1991-08-06 Atochem North America, Inc. Polymer bound flame retardants
US5220015A (en) * 1988-11-07 1993-06-15 Elf Atochem North America, Inc. Flame retardants compounds
US5140070A (en) * 1988-11-07 1992-08-18 Elf Atochem North America, Inc Compositions comprising polymer bond flame retardants
US4958782A (en) * 1988-12-28 1990-09-25 Pitney Bowes Inc. Reeled tape supply
JPH0778025B2 (ja) * 1990-03-20 1995-08-23 日本赤十字社 免疫グロブリンｇの製造方法
US5320812A (en) * 1993-10-04 1994-06-14 Becton, Dickinson And Company Clot activating polyelectrolyte complex and blood collection assembly containing same
US9764319B2 (en) * 2011-06-02 2017-09-19 Universidad De Santiago De Chile Biomarkers related with a supra-nutritional metabolic state of selenium and diagnosis method in which said biomarkers are identified
CN103797023B (zh) * 2011-09-16 2020-04-10 通用电气医疗集团生物工艺研发股份公司 通过序贯多元酸沉淀进行的血浆蛋白分级分离
WO2025118020A1 (en) * 2023-12-07 2025-06-12 The University Of Queensland A polymer for improved purification of extracellular vesicles

Also Published As

Publication number Publication date
DE2026076A1 (enExample) 1970-12-03
DE2026076B2 (de) 1979-05-10
CA925017A (en) 1973-04-24
BE751088A (fr) 1970-11-30
US3555001A (en) 1971-01-12
NL7007707A (enExample) 1970-12-01
GB1269868A (en) 1972-04-06
NL170419B (nl) 1982-06-01
FR2048934A5 (enExample) 1971-03-19
NL170419C (nl) 1982-11-01

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)