DE1942849A1 - Liquid enzymatic detergent preparations - Google Patents

Description

concerning
' ^! liquid enzymatic detergent preparations "

The invention relates to liquid enzymatic detergent preparations

Encyclopedias have become more and more popular in "the last" years. in all types of powder detergents and laundry detergents along with. surfactants? Building salts and often also with bleachf) - has been used < >

Liquid detergent preparations are excellent for washing fine fabrics, all kinds of other laundry. Waseh-Vorwasch or Jli ^ wei chm.ittßl tvgc household linen are used. Purch The use of liquid detergents are the disadvantages of powdery enzyme detergents, such as poor or slow solubility, the heterogeneous composition of the detergent and the clumping when stored in one humid environment largely or completely overcome _o It would therefore be

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a big advantage1 liquid enzymatic detergent supplies to have rides available.

However, it is known that enzymes in aqueous medium, odgr inactivated even in a humid atmosphere can be and that certain surface-active substances-and / -o4er Building materials are incompatible with enzymes, especially in the presence of moisture *

Wk. This is particularly true for polyphosphates, which are often used as building salts in powder detergents containing enzymes. enzymes are also inactivated when they are "brought into an aqueous medium together with polyphosphates." It is therefore only logical that one tends to think that liquid detergent preparations should not contain polyphosphates.

Surprisingly, it has now been shown that it is dUPPhgugi jjiQglieh to deliver liquid enzymatic petroleum preparations. which have an excellent y / asch ■ ■ effect when an Oflgr m ^ hrgr-e. Pelyphosphates. z, u add to the preparationi; be "E§ has §iQh approved _t that the healing effect in insr gQlphen Z, ub, grgituö, g Ja.Rgg.Zeit P3? Jh, aJt.en • remains ΗΏ4 s _t pgar bgssgi- eats a% s digjgijigg ^ vpn §im $ fris, ß | i-

lietergen-jiign. ^ Z.ubgp.eitung phne || | (| §R (Datgaplig dag Vi | rp

The, Abnahlg & §φ Enz ^ makti ^ ät in vitro wipiä f; ür? E | ¹ #: 3-le, in thin. lplypiigsphate §nv ¥ §§ßn, 4 §ind.Q4§? not anwgggnq in

Dig enzyme activity in vitro is determined by measuring time determined in min,: dig for hydrolysis of a -specific volume.-V

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Protein is required . The enzyme activity of the following compounds was determined using Alcalase (NOVO Industrie) as the enzyme.

1. Enzymatic detergent mixture, which is in dry form

was kept.
2 «Enzymatic detergent mixture that has been stored in liquid form,

3. Mixture 2 to which polyphosphates were added 4 x Mixture 2 to which orthophosphates were added.

at pH 6 Table 1 at pH 8 After 3
Weeks Immediately After 1
week Immediately After 1
Where before 10.40
15.58,
52.90
14.97 Preparation
tion 10.40
10.20
17.58
12.95 10.40
12.08
26.95
16.01 After 3
μochen 10.40
10.48
13.68
11.10 10.40
11.25
26.10
12.40, 1
2
3
4th 10.40
12.62
29.30
17.43

The table above clearly shows that

a) None for laundry detergents and cleaning agents in dry form Decrease in enzyme activity is observed;

b) the decrease in enzyme activity in a solution, the enzymes and containing polyphosphates, is greatest;

c) the EnzyEaktivitkt in vitro of liquid enzymatic detergent mixtures containing polyphosphates, after a storage time of 5 "ochen, substantially waned.

From the table above, the conclusion can be drawn, that a liquid detergent preparation, but the enzymes '' contains no polyphosphates, (preparation 2) the greatest washing effect owns. From the following data relating to washing

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refer to experiments that have been carried out with various liquid detergent preparations, it turns out, however, that this conclusion is incorrect and that medcwur-! However, it is precisely the preparation with the lowest enzyme activity in vitro that has the greatest Y / ash effect, β ^J

The washing effect of 6 liquid detergent preparations with and without protease was carried out on pieces of a test material determined by measuring the reflection values. Each experiment was carried out eight times and the middle " Reflection value was included in the table Y / ir under- * looked for the following preparations:

1. Basic preparation, consisting of surface-active substances and building salts (no polyphosphates and phosphates).

2. Basic preparation 1 to which a protease has been added.

3. Basic preparation 1 to which polyphosphates were added »4 · Preparation 3 to which a protease was added ₀ '

5. Basic preparation 1 to which orthophosphates have been added. 6 "Preparation 5 to which a protease has been added"

at pH 6 Tabel 2 at pH 8 After 3 Immediately laugh 1 Immediately Night Weeks. Preparation / V / o ehe After 3 week -14.5 tion 14.6 ■ 13.4 Woeheη 14 ", 7 14.9 23.4 1 22,, 7 24.7 11.4 27.9 25.1 25.9 2 "/ 1Y, 9 19.7 25.9 25.8 26.3 37.9 3 ■■: '■ 34.8 36.0 18.6 46.8 43.1 14.6 4th 11.1 12.7 32.6 15.1 15.8 5 11.5

6 15.1 16.4 15.9 22.3 23.3 22.8

The pieces of the experiment were fabrics (empacloths) that had been artificially soiled with a substrate of blood, ink and sugar. The protease used was ijlcalase (I70V0 Industry). 009009/1672

ORIGINAL

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The table clearly shows that the reflection value of the liquid detergent preparation containing protease and polyphosphates (4) is the highest, even after 3 weeks long storage, despite the fact that the enzyme activity in vitro of this preparation decreases faster than that of the other enzymatic preparations without polyphosphates

The enzymes used in the present invention are enzymes with significant proteolytic activity. These enzymes hydrolyze the proteins. Proteolytic Enzymes are obtained from animal organs, from plants and from fungal and bacterial cultures

Examples of Enzyrne ^ MIIT essentially proteolytic effect "which are suitable for use in the inventive detergents formulations are: \

Aloalaee (HOVO Induetrie Copenhagen) Maxatase (Koninklijke Nederlandse Grist- en Spjritusfabriek) Protease B and AP (Schweizerische Ferment A.G.) Honzym AP (Monsanto) Biopraee DBP and BPIO. g »* & e (Hagaae Japan) ATP. 120 (Sooiett Rapidase) Pancreas Proteaee (Organon N.V.)

The amount of proteolytic enzymes contained in the liquid detergent preparation according to the invention naturally depends on the activity of the protease used. In general, it is sufficient to ensure that the proteolytic activity is 1 * 75 Anson units / l dgs freshly manufactured end product. Anson units are defined in Ml ·. Anson "T, Gen. Pby 22, 79 (1938).

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. In addition to the proteolytic enzymes mentioned, " The preparation according to the invention contains small amounts of other enzymes, such as amylolytic and / or lypolytic enzymes, a.B Amylaae from Baaillu Subtilia (NOVO) and microbiological Iiypaae ·>

. As surface-active substances, all substances with such an activity can be used in the preparation according to the invention in an amount of 1-50% by weight, based on the total Preparation can be used »Preferably non-ionic and / or anionic surface-active substances can be used» both in combination with amphoteric surface-active substances or without them ·

Examples of known anionic surface-active substances are t The sodium, potassium or ammonium salts of! higher fatty acids such as the stearates, palmitates and myristates; Petroleum alcohol polyglyicol ether carboxylic acids or their salts, 'alkyl sulfates, allyl sulfonate, alkyl aryl sulfonate, alkyl ether sulfonates, sulfonation products of olefins and derivatives of maleic acid

Examples of known and widespread non-ionic surface-active substances are "The condensation products aua polyethylene oxide or polypropylene bjcid with fatty acids, Alcohols or amides, such as a »B. Alkyl polyglycol ether, alkyl

and aoyl polyglycol ether.

The amphoteric surfactants include e.g. the surface-active derivatives of the Bekunderen and TertiäVeri Amines and the quaternary ammonium compounds, ihoaphonium- or sulfonium compounds Widespread aind the ampho » tertiary detergents of the betaine type »/ f:

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The building salts in the preparation according to the invention * Mainly water-soluble, reinforcing, organic or inorganic salts can be used

Examples of suitable inorganic salts are: alkali carbonates, - borates, - sulfates, - silicates, -bicarbonates and phosphates, -

Examples of organic builders salts are j - ¹ He water-soluble poly-phosphonates, such as the sodium, - potassium, or lithium salts of methylenediphosphonic acid or] \ thylendiphosphonsaure, the water-soluble polymers Polycarhoxylate and salts of complexing agents such as EDTA and KTA. The organic and inorganic building salts can be used either separately or together.

The most important component, according to the invention in the contain liquid ensymatic "detergent preparation must be, is' the rolyphoephat, which is also part of the building blocks heard.

With polyphosphates!) The water-soluble Iyrophosphate and polymeric phosphates are meant, like ζ.3, HeyamethyphoFpbate and Tripolxphosphate or mixtures of these two substances. The polyphosphates should be contained in the preparation according to the invention in amounts of up to eu 50 ρ of the total preparation and preferably in lengths of over 1 % . The Polyjhocphate can sun: groscen part of the function of the previously he \ v ^f -HN- th Aufbausal '^ e übern never before, "but they can also sus & aRNC-n nit d ^ eeen substances. examples for this are

Ftt-Phcsphatgemisehe Or a combination of foils with a mixture of phosphates and other building salts. ·

The polyphosphates ",, rtie all of · comparable effect on the Tssehvarkung" besitiien, wenr, rie to "the flvssisen '_

BAt ORIQiNAL

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Preparation together with the enzymes, surface-active Substances and possibly building salts are added, the pyrophosphates are preferred because they are in contrast to hydrolyze other polyphosphates less quickly in an aqueous medium *

The pH at which the proteolytic enzymes have their greatest activity, varies widely but is generally 4 to 10, the preparations according to the invention, the _f mainly enzymes, surfactants "substances and polyphosphates may superstructure salted meats along with other up-%. contain, maintain their extremely high washing effect over the entire pH range of 4-10 »but they - have the greatest effect between pH 5» 5 and pH 8. Very good results have been achieved with a liquid enzymatic detergent preparation Protease, pyrophosphate and anionic surfactants obtained at pH 6 after standing for three months at room temperature. Comparable results were obtained with a liquid preparation of protease, a mixture of ionic and nonionic surface-active substances and a pyrophosphate / orthophosphate mixture at pH after standing for three months,

if- - '

In addition to the substances mentioned above, namely the The liquid preparation can contain "surface-active substances", enzymes, polyphosphates and possibly other structural salts according to the invention also additionally hydrotropic substances ι included, with which the viscosity of the preparation is regulated can be, and with which a possible separation In two Phases is avoided. If necessary, the preparation according to the invention can contain further additives such as perfume,! Colorants, bacterial oids and enzyme stabilizers, e.g. sulfites and contain pyrosulfites, depending on the purpose for which the preparation according to the invention is to serve.

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The present liquid enzymatic detergent preparations can be sold as such but they can also do very well with aerosols as sprays; to be used « j '*

The invention is accomplished through the following preparations explained in more detail, which have been prepared by mixing the compounds mentioned below in water with one another has mixed

I. ·

Example 1 follows

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9-2849

K ₄ P ₂ O ₇

- 10 - zjisj 1A- 36 715 9 example 1 A. 12th 9 lft.JÜ1_J 12th preparation
B CD 5 9 9 12 12 ! ulphonat mm mm

Sodium alkylbenzenesulphonate + nonylphenol ethoxylate (2s 1)

Tego betaine

Steinapol S 1392 (mixture of sodium dodecylbenzene sulphonate and thiosuccinic acid half-ester sodium xylene sulphonate hexylene glycol
Maxatase 4-0.000
Water except for

After standing for 3 months:

Yeast reflectance value without maxatase 17.5 14.0 8.0 12.5

with Maxatase 27.0 26.0 17.5 27.0

- - - - - 5 ■ 5 5 5 5 3 3 3 3 1 1 1 1 100 100 100 100

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• ■,, * - - ■, Example 3 A Example 3 B 1942 1A- 36715 849 ~ 11 - K ₄ P ₂ O ₇
Nonylphenol ethoxylate Example 2 Oleic alcohol ethoxylate 9 #
12 i>
io io K ₄ P ₂ O ₇
Na ₂ H ₂ P ₂ O ₇
Elfan (sodium lauryl ether sulphate) Steinapol S 1392 196 Tego Bstain Orthophosphate 5 96 Xylene sulphonate EDTA sodium salt 0.7 96 Alcalase, Optical brightener 100 96 Water except for Opacifiers, ' • ■ - - -
Perfume O Iy
C / V
4 ok A.T.P. 120 Water except for 7.5 t 3 96 * 1 96 ΟΛ5 96 0.7 96 0.1 io 1 ok 100 #

The enzyme A.T.P. 120 was used in the above preparation by Monzym AP, which is both proteolytic and Aaylase * Activity owns, replaces.

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Example 4 Example 5 A Example 5 B 7 * Sodium tripolyphosphate Hexamethaphosphate 7 96 Sodium Lauryl Sulphate Sodium alkylbenzenesulphonate 5 9δ lego Betaine L 7 Nonylphenol ethoxylate 2? 6 Sodium disilicate Coconut monoethanolamide 0.25% Hydromethyl cellulose (metofas) Xyl oil sulphonate
«- _ ■ 0.1 96 Perfume Opacifiers 1 96 .- ■■: Alcalaae Perfume ',. 100 96 Water except for Optical brightener ■. Vi
. - i Alcal'ase 6 #, Water except for -6 * 4? 6 1 96 5 96 0.1 ^ 0.1 ^ 0.3 96 1 96 100%

In the above preparation, the hexametaphosphate was replaced by 6 i 'tripolyphosphate.

XX 44 VI. Claims

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Claims (5)

Pat e η ta η. a ρ back e 1. Liquid «enzymatic detergent preparations that surface-active substances, building salts, proteolytic enzymes and contain water, thereby g e k e η η ζ e lehne t, that they contain 1-50 wt .- ^ polyphosphates. 2. Detergent preparations according to claim 1, characterized in that the freshly prepared preparations contain 5-50 wt. 3. Detergent preparations according to claim 1 and 2, characterized - characterized, Sans üas polyphosphate is a pyrophosphate. \, 4. Detergent preparations according to claim 1 to 3 »thereby marked that the surface'inactive Substances are anionic and / or non-ionic substances that can be used either alone or in combination with amphoteric surfactants. 5. detergent preparations according to claim 1 to 4? through this g e k, -e η 'η ζ e i e h η e t that you have one from 5 »5 - 8 own. XX / XI 009809/167