DE1792329A1 - Insecticidal synergistic mixtures - Google Patents

Description

^ fHFRIKIGAG ι berlin es, the 1β. August 1968

JUiblMlNU / iU garbage ^ tr. 170.172. Femmf ^ OOM PATENT DEPARTMENT Η «π · .η · ΛΙα6 No. 1

Dr Lie / Kl / P.1090

- Insecticidal synergistic mixtures (elimination from patent application Sch 29 672 IVa / 45 l)

It has been found that the action of insecticidally effective 5- (1-Isopropyl-3-methylpyrazolyl) -N, N-dimethylcarbamate the addition of insecticidally inactive carbamates synergistically is reinforced.

As insecticidally inactive carbamates according to the invention Compounds are understood to be up to a dose of about O, δ mg / dm up practically no killing of insects / while 5- (1-isopropyl-j5-methylpyrazolyl) -N, N-dimethylcarbamate is fully effective below this dose.

In comparison to the sole use of the insecticidally active carbamates for combating insects, application of the devices according to the invention increases in particular the degree of effectiveness and shortens the initial effect, which means that the control can be made more reliable. In addition, it was found that in the case of the mixtures, compared to the insecticidally active carbamate, the warra blood toxicity can be reduced, which means that the control of harmful insects when using these mixtures is compared to the sole application of the insecticidally active individual components contained in them for the ? can be carried out more safely as for pets

The compounds from the class of carbamates, in which In *

109844/1745 '

BATH ORIGINAL

-St-. P. 1090 / 16.8.1Q68

Secticidal effectiveness was found to include ζ. Β.

J-methyl-S-isopropylphenyl-N-methyloarbamate,

1-naphthyl-N-methylcarbamate,

3-isopropylphenyl-N-methylcarbamate,

5- (1-Isopropyl-J-methylpyrazolyl) -N, N-dimethylcarbamate.

It is also known that one has the expected additive effect significantly superior increase in effectiveness with mixtures of

• Because there are 2 different «already known carbamate insecticides exists as analog synergism. However, this observation comes no general meaning, as predictions about the one Connection own potentiating effect after combined application with known biologically active substances because of today There is still a lack of knowledge of the underlying synergism Mechanisms of action in the insect organism are not possible. It was therefore surprising that according to the present application Mixtures of insecticidally active 5- (l-isopropyl-3-methylpyrazolyl) -N, N-dimethylcarbamate with inactive carbamates one show substantial and in all cases significant synergism.

The synergistic mixtures according to the invention can be used alone or along with other pesticides, such as insect! zi-. acaricides or fungicides are used. The preparation takes place in a usual for plant protection products Form using liquid or solid carriers. Suitable liquid carriers include water and mineral oils or solvents; suitable solid supports are e.g. B. bentonite. Fuller's earth, gypsum, lime, diatomite, pyrophyllite, silicon dioxide or talc · The preparations can also contain additives such as

109844/1745

: -5- P. 1090 / 16.8.1968

Emulsifiers, wetting agents or binders, propellants, fragrances, stabilizers, attractive substances or repellents. The means can, among other things, as dust, grit or granulate, as nebulizable, sprayable or sprayable liquids, as Aerosols or fumigants are used

The amount of the synergistic mixture used in crop protection products to be used can vary within wide limits. It depends, among other things, on the ratio of the components the type of preparation, the method of application, the desired Control success and the type of pests to be controlled away"

Depending on the form of preparation, the content of the synergistic mixture can be between about 0.1 and 0 percent by weight of the agent, which can be used in concentrations down to 0.001 percent by weight. In general, however, use concentrations between about 0.025 and 10 % in liquid or solid carriers give excellent results. For some purposes, higher use concentrations may be desirable.

In the synergistic mixtures according to the invention, the weight ratio of the components generally from about 25 to 1 part by weight of the effective and from about 1 to 50 parts by weight of ineffective components will be 'Preferably' synergistic mixtures with a weight ratio of 1 to 10 parts of the active carbamate to 5 to 50 parts of the inactive Connections used

BATH ORIGINAL ,,

109844/1745 "*"

"* · P> 1090 / 16.8.1900

In repeated laboratory tests, those listed in Table 1 were CarbamldeiiurooBtor after dosed application (4 rag / cm) as ■ aqueous emulsions up to concentrations of at least 0.25 percent by volume ineffective against

House flies (Musca domestica L.) after 24 hours Continuous exposure to spray coatings «

Corn beetle (Sitophilus granarius L.) after 4 days Permanent exposure to spray coatings,

Stick insect (Carausius morosus Brunner) after Immersion treatment and 5 days exposure on treated Forage plants "

Cockroaches (Blätella germanica L., Periplaneta americana L., Leucophaea maderae F.) after dew treatment or after 4 days expoeition on Stbt

Gypsy moth caterpillars (Lymantrla dispar L.) after dosed animal treatment and exposure of the larvae to treated forage plants for 4 days.

The comparison with the today known, under the same Versuohsbedingungen insecticides that are fully effective in much lower concentrations, the ineffectiveness of the compounds tested here, which your economically justifiable use In the practical Pest control hardly justifies, particularly clearly.

Table 1 Ineffective carbamic acid esters

. Compound No. Chemical

1 ^ roi

phenyl) ester

^ Benzyl-NiN-diallylcarbamal,

SCHERING AG, -5- P «1090 / August 16, 1968

Compound chemical name

5 β- (butoxy-ethoxy) -ethyl-N ₁ N-diallyl-carbamate

6 Ethylenimine-N-carboxylic acid octyl ester

7 2-propenyl-4-methylphenyl-N-methyl-carbamate

The above compounds were found to be effective in admixture with the known carbamate

D. 5- (1-Isopropyl-3-methylpyrazolyl) -N, N-dirnethylearbamate

tested in different relationships of the individual components. From the following example the synergistic effect is that of the invention Mixtures visible. The efficiencies given in Table 2 relate to mean values from at least two series of experiments carried out under constant conditions.

example

To test the contact effect on stick hayfish (Carausius Korosus Brunner) fifteen frieoh-skinned larvae IV were immersed for three seconds in aqueous emulsions of the mixtures according to the invention, freed from excess liquid on filter paper and placed in a wire gauze cage. Tradeso drive drives set as fodder plants. During daily health checks, there were between dead and severely damaged, if only on contact with disordered extremities. A distinction was made between experimental animals that responded with poor reactions, as well as slightly damaged and normally surviving test animals.

109844/1745 ,

SCHERING AG

T a_b

Contact effect of synorgiotic Gorais on Carausius raoroeua DRUNNER (Larvon XV) after Tauohkontakt

link
(Description

Drug concentration in percentage effect after> 4 T aften "

0.25

0.5

_k5

10
42
67

10

56

83

10 60 93

12th

67 100

Synergistic
Oemics from

D.
D.
D.
D.
P.
D.

1
2

0.06
0.06
0.06
Ο, Οδ
0.06
0.06
0.06 ♦ ■

0.06

ο, οβ 0.06 0.06

o, o6 0.06 0.06

40

63 37 33 30 50

50 60 80 50 50

Ϊ ⁵ 60

50 60 60 60 80 80 50 60 50 60 43 45 60 67

10 9844A174S

BATH ORIGINAL

Claims (1)

SCHERING AG P.IO9O / August 16, 1968 Claim Insecticide containing a synergistic mixture of carbamates, characterized «that it is one of the in a dose up to about 0.8 mg / dm up insecticidally inactive garbamate Pyrrolidine-N-carboxylic acid (5-methyl-5-isopropylphenyl) ester, Piperidine-N-carboxylic acid (3,5-dimethylphenyl) ester, Benzyl ^ N-diallyl carbamate, Dodecyl-N, N-diallyl carbamate, ß - (But oxy-ätho3Ey) -äthy 1-N, N-dial Iy lcarbamat Ethylenirain-N-carboxylic acid octyl ester or 2-propenyl-4-diethylphenyl-N-methylearbaniate in a mixture with the insecticidally active below this dose 5- (1-Isopropyl-5-methylpyrazolyl) -N, N-dimethylarbarate contains.