DE112022001882T9 - Krebstherapie unter verwendung von toll-like-rezeptor-agonisten - Google Patents

Krebstherapie unter verwendung von toll-like-rezeptor-agonisten Download PDF

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Publication number
DE112022001882T9
DE112022001882T9 DE112022001882.8T DE112022001882T DE112022001882T9 DE 112022001882 T9 DE112022001882 T9 DE 112022001882T9 DE 112022001882 T DE112022001882 T DE 112022001882T DE 112022001882 T9 DE112022001882 T9 DE 112022001882T9
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Germany
Prior art keywords
administered
procedure according
tlr9 agonist
dose
liver
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Active
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DE112022001882.8T
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German (de)
English (en)
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DE112022001882T5 (de
Inventor
Steven C. Katz
Bryan F. Cox
David Benjamin Jaroch
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Trisalus Life Sciences Inc
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Trisalus Life Sciences Inc
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Publication of DE112022001882T5 publication Critical patent/DE112022001882T5/de
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE112022001882.8T 2021-04-01 2022-03-31 Krebstherapie unter verwendung von toll-like-rezeptor-agonisten Active DE112022001882T9 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163169674P 2021-04-01 2021-04-01
US63/169,674 2021-04-01
US202263298589P 2022-01-11 2022-01-11
US63/298,589 2022-01-11
PCT/US2022/022801 WO2022212690A1 (en) 2021-04-01 2022-03-31 Cancer therapy using toll-like receptor agonists

Publications (2)

Publication Number Publication Date
DE112022001882T5 DE112022001882T5 (de) 2024-01-18
DE112022001882T9 true DE112022001882T9 (de) 2024-02-29

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DE112022001882.8T Active DE112022001882T9 (de) 2021-04-01 2022-03-31 Krebstherapie unter verwendung von toll-like-rezeptor-agonisten

Country Status (7)

Country Link
EP (1) EP4313315A1 (ko)
JP (1) JP2024512765A (ko)
KR (1) KR20240004419A (ko)
AU (1) AU2022249092A1 (ko)
CA (1) CA3215582A1 (ko)
DE (1) DE112022001882T9 (ko)
WO (1) WO2022212690A1 (ko)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002052002A2 (en) 2000-12-27 2002-07-04 Dynavax Technologies Corporation Immunomodulatory polynucleotides and methods of using the same
US20040009151A1 (en) * 2002-04-04 2004-01-15 Kay Mark A. Methods for delivering recombinant adeno-associated virus virions to the liver of a mammal
US8158768B2 (en) 2002-12-23 2012-04-17 Dynavax Technologies Corporation Immunostimulatory sequence oligonucleotides and methods of using the same
US7963956B2 (en) * 2003-04-22 2011-06-21 Antisense Pharma Gmbh Portable equipment for administration of fluids into tissues and tumors by convection enhanced delivery technique
US8696698B2 (en) 2009-12-02 2014-04-15 Surefire Medical, Inc. Microvalve protection device and method of use for protection against embolization agent reflux
US9539081B2 (en) 2009-12-02 2017-01-10 Surefire Medical, Inc. Method of operating a microvalve protection device
US8500775B2 (en) 2009-12-02 2013-08-06 Surefire Medical, Inc. Protection device and method against embolization agent reflux
US9770319B2 (en) 2010-12-01 2017-09-26 Surefire Medical, Inc. Closed tip dynamic microvalve protection device
US9968740B2 (en) 2014-03-25 2018-05-15 Surefire Medical, Inc. Closed tip dynamic microvalve protection device
US20160287839A1 (en) 2015-03-31 2016-10-06 Surefire Medical, Inc. Apparatus and Method for Infusing an Immunotherapy Agent to a Solid Tumor for Treatment
US10806893B2 (en) 2017-01-10 2020-10-20 Surefire Medical, Inc. Guiding catheter having shape-retentive distal end
US10588636B2 (en) 2017-03-20 2020-03-17 Surefire Medical, Inc. Dynamic reconfigurable microvalve protection device
US20190298983A1 (en) 2018-01-15 2019-10-03 Surefire Medical, Inc. Injection Port for Therapeutic Delivery
WO2019160866A2 (en) * 2018-02-13 2019-08-22 Checkmate Pharmaceuticals, Inc. Compositions and methods for tumor immunotherapy
US11850398B2 (en) 2018-08-01 2023-12-26 Trisalus Life Sciences, Inc. Systems and methods for pressure-facilitated therapeutic agent delivery
US20200383688A1 (en) 2019-06-04 2020-12-10 Surefire Medical, Inc. Atraumatic Occlusive System with Compartment for Measurement of Vascular Pressure Change
WO2021011496A1 (en) * 2019-07-12 2021-01-21 Oregon Health & Science University Immunotherapeutic constructs and methods of their use

Also Published As

Publication number Publication date
KR20240004419A (ko) 2024-01-11
WO2022212690A1 (en) 2022-10-06
AU2022249092A1 (en) 2023-10-12
AU2022249092A9 (en) 2023-10-26
JP2024512765A (ja) 2024-03-19
EP4313315A1 (en) 2024-02-07
CA3215582A1 (en) 2022-10-06
DE112022001882T5 (de) 2024-01-18

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