DE112012006079T5 - Peritonealdialyse-Systeme, -Vorrichtungen und -Verfahren - Google Patents
Peritonealdialyse-Systeme, -Vorrichtungen und -Verfahren Download PDFInfo
- Publication number
- DE112012006079T5 DE112012006079T5 DE112012006079.2T DE112012006079T DE112012006079T5 DE 112012006079 T5 DE112012006079 T5 DE 112012006079T5 DE 112012006079 T DE112012006079 T DE 112012006079T DE 112012006079 T5 DE112012006079 T5 DE 112012006079T5
- Authority
- DE
- Germany
- Prior art keywords
- fluid
- pump
- flow
- batch
- concentrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title claims abstract description 135
- 238000000502 dialysis Methods 0.000 title claims abstract description 106
- 239000012530 fluid Substances 0.000 claims abstract description 599
- 239000000385 dialysis solution Substances 0.000 claims abstract description 53
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 188
- 239000012141 concentrate Substances 0.000 claims description 177
- 238000011282 treatment Methods 0.000 claims description 141
- 238000005086 pumping Methods 0.000 claims description 81
- 238000002156 mixing Methods 0.000 claims description 80
- 239000002357 osmotic agent Substances 0.000 claims description 78
- 239000003792 electrolyte Substances 0.000 claims description 69
- 238000011049 filling Methods 0.000 claims description 61
- 238000012546 transfer Methods 0.000 claims description 50
- 238000004519 manufacturing process Methods 0.000 claims description 41
- 238000010790 dilution Methods 0.000 claims description 32
- 239000012895 dilution Substances 0.000 claims description 32
- 230000004044 response Effects 0.000 claims description 30
- 230000002572 peristaltic effect Effects 0.000 claims description 28
- 210000004303 peritoneum Anatomy 0.000 claims description 26
- 230000007246 mechanism Effects 0.000 claims description 21
- 230000001276 controlling effect Effects 0.000 claims description 15
- 239000008213 purified water Substances 0.000 claims description 15
- 230000008859 change Effects 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 12
- 230000003213 activating effect Effects 0.000 claims description 11
- 239000003795 chemical substances by application Substances 0.000 claims description 11
- 238000004891 communication Methods 0.000 claims description 11
- 238000001514 detection method Methods 0.000 claims description 11
- 230000005540 biological transmission Effects 0.000 claims description 10
- 238000010926 purge Methods 0.000 claims description 10
- 230000001351 cycling effect Effects 0.000 claims description 9
- 239000008223 sterile water Substances 0.000 claims description 9
- 230000009471 action Effects 0.000 claims description 8
- 239000003814 drug Substances 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- 230000001105 regulatory effect Effects 0.000 claims description 6
- 239000003085 diluting agent Substances 0.000 claims description 5
- 229940079593 drug Drugs 0.000 claims description 5
- 230000004913 activation Effects 0.000 claims description 4
- 238000007865 diluting Methods 0.000 claims description 4
- 239000004033 plastic Substances 0.000 claims description 4
- 238000010923 batch production Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000000284 extract Substances 0.000 claims description 2
- 210000003567 ascitic fluid Anatomy 0.000 abstract description 3
- 230000008569 process Effects 0.000 description 41
- 238000000746 purification Methods 0.000 description 30
- 230000006870 function Effects 0.000 description 20
- 238000005259 measurement Methods 0.000 description 17
- 239000000047 product Substances 0.000 description 16
- 238000007726 management method Methods 0.000 description 14
- 238000012360 testing method Methods 0.000 description 14
- 239000012528 membrane Substances 0.000 description 13
- 239000000243 solution Substances 0.000 description 13
- 230000001954 sterilising effect Effects 0.000 description 13
- 238000006073 displacement reaction Methods 0.000 description 12
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 11
- 239000008103 glucose Substances 0.000 description 11
- 210000004379 membrane Anatomy 0.000 description 11
- 238000004659 sterilization and disinfection Methods 0.000 description 11
- 208000028659 discharge Diseases 0.000 description 10
- 210000003200 peritoneal cavity Anatomy 0.000 description 10
- 230000033228 biological regulation Effects 0.000 description 9
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 8
- 238000001914 filtration Methods 0.000 description 8
- 230000029058 respiratory gaseous exchange Effects 0.000 description 8
- 238000003860 storage Methods 0.000 description 8
- 238000011109 contamination Methods 0.000 description 6
- 238000013461 design Methods 0.000 description 6
- 230000009975 flexible effect Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 5
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 239000004202 carbamide Substances 0.000 description 5
- 238000004590 computer program Methods 0.000 description 5
- 239000000470 constituent Substances 0.000 description 5
- 208000015181 infectious disease Diseases 0.000 description 5
- 238000012986 modification Methods 0.000 description 5
- 230000004048 modification Effects 0.000 description 5
- 239000002243 precursor Substances 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 238000009530 blood pressure measurement Methods 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 238000007599 discharging Methods 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 230000005484 gravity Effects 0.000 description 4
- 238000001223 reverse osmosis Methods 0.000 description 4
- 230000002441 reversible effect Effects 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 238000002242 deionisation method Methods 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000004907 flux Effects 0.000 description 3
- 230000033001 locomotion Effects 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 238000001631 haemodialysis Methods 0.000 description 2
- 230000000322 hemodialysis Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000000977 initiatory effect Effects 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 230000000422 nocturnal effect Effects 0.000 description 2
- 239000003330 peritoneal dialysis fluid Substances 0.000 description 2
- 206010034674 peritonitis Diseases 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 102220012182 rs373164247 Human genes 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 238000000108 ultra-filtration Methods 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 1
- 102220619039 28S ribosomal protein S12, mitochondrial_S61E_mutation Human genes 0.000 description 1
- FIKFLLIUPUVONI-UHFFFAOYSA-N 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one;hydrochloride Chemical compound Cl.O1C(=O)NCC11CCN(CCC=2C=CC=CC=2)CC1 FIKFLLIUPUVONI-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 102220605052 Histone H4-like protein type G_S61A_mutation Human genes 0.000 description 1
- 229920002177 Icodextrin Polymers 0.000 description 1
- 102220534918 Importin subunit alpha-6_S61D_mutation Human genes 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 244000089486 Phragmites australis subsp australis Species 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 102220534415 Tyrosine-protein phosphatase non-receptor type 1_S50D_mutation Human genes 0.000 description 1
- 102220596165 Uncharacterized protein C1orf131_S52A_mutation Human genes 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 210000003815 abdominal wall Anatomy 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- 239000000823 artificial membrane Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 102220352372 c.148T>G Human genes 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000003245 coal Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000003113 dilution method Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 208000028208 end stage renal disease Diseases 0.000 description 1
- 201000000523 end stage renal failure Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- 238000005429 filling process Methods 0.000 description 1
- 239000013020 final formulation Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229940016836 icodextrin Drugs 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 238000003760 magnetic stirring Methods 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 230000009022 nonlinear effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000012354 overpressurization Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000013102 re-test Methods 0.000 description 1
- 230000003134 recirculating effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000009256 replacement therapy Methods 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 102220265335 rs139105272 Human genes 0.000 description 1
- 102220068611 rs140047528 Human genes 0.000 description 1
- 102200082820 rs33960931 Human genes 0.000 description 1
- 102220005308 rs33960931 Human genes 0.000 description 1
- 102220053041 rs543765307 Human genes 0.000 description 1
- 102200112524 rs9895963 Human genes 0.000 description 1
- 102220102960 rs9895963 Human genes 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000005204 segregation Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 101150051314 tin-10 gene Proteins 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/152—Details related to the interface between cassette and machine
- A61M1/1524—Details related to the interface between cassette and machine the interface providing means for actuating on functional elements of the cassette, e.g. plungers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/154—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with sensing means or components thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/155—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with treatment-fluid pumping means or components thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
- A61M1/1565—Details of valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
- A61M1/159—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit specially adapted for peritoneal dialysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
- A61M1/166—Heating
- A61M1/1664—Heating with temperature control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
- A61M1/1668—Details of containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/282—Operational modes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/285—Catheters therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/288—Priming
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
- A61M2205/128—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2012/030350 WO2012129501A2 (en) | 2011-03-23 | 2012-03-23 | Peritoneal dialysis systems, devices, and methods |
| USPCT/US12/30350 | 2012-03-23 | ||
| PCT/US2012/056781 WO2013141896A1 (en) | 2012-03-23 | 2012-09-23 | Peritoneal dialysis systems, devices, and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE112012006079T5 true DE112012006079T5 (de) | 2014-12-04 |
Family
ID=49223962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE112012006079.2T Withdrawn DE112012006079T5 (de) | 2012-03-23 | 2012-09-23 | Peritonealdialyse-Systeme, -Vorrichtungen und -Verfahren |
Country Status (4)
| Country | Link |
|---|---|
| EP (4) | EP3482786B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6407856B2 (cg-RX-API-DMAC7.html) |
| DE (1) | DE112012006079T5 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013141896A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7736328B2 (en) | 2007-07-05 | 2010-06-15 | Baxter International Inc. | Dialysis system having supply container autoconnection |
| US9399091B2 (en) | 2009-09-30 | 2016-07-26 | Medtronic, Inc. | System and method to regulate ultrafiltration |
| DE112012001381T5 (de) | 2011-03-23 | 2014-01-02 | Nxstage Medical, Inc. | Peritoneal-Dialyse-Systeme, -Vorrichtungen und -Verfahren |
| US9561316B2 (en) | 2011-04-29 | 2017-02-07 | Medtronic, Inc. | Intersession monitoring for blood fluid removal therapy |
| JP6001660B2 (ja) | 2011-08-02 | 2016-10-05 | メドトロニック，インコーポレイテッド | 制御された追従的な容積を有する流路を有する血液透析システム |
| US10857277B2 (en) | 2011-08-16 | 2020-12-08 | Medtronic, Inc. | Modular hemodialysis system |
| US10905816B2 (en) | 2012-12-10 | 2021-02-02 | Medtronic, Inc. | Sodium management system for hemodialysis |
| US10850016B2 (en) | 2013-02-01 | 2020-12-01 | Medtronic, Inc. | Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection |
| US10010663B2 (en) | 2013-02-01 | 2018-07-03 | Medtronic, Inc. | Fluid circuit for delivery of renal replacement therapies |
| US9623164B2 (en) | 2013-02-01 | 2017-04-18 | Medtronic, Inc. | Systems and methods for multifunctional volumetric fluid control |
| US10543052B2 (en) | 2013-02-01 | 2020-01-28 | Medtronic, Inc. | Portable dialysis cabinet |
| US9827361B2 (en) | 2013-02-02 | 2017-11-28 | Medtronic, Inc. | pH buffer measurement system for hemodialysis systems |
| EP3102107A4 (en) | 2013-11-04 | 2018-02-07 | Medtronic, Inc. | Method and device to manage fluid volumes in the body |
| DE102014109369A1 (de) * | 2014-07-04 | 2016-01-07 | B. Braun Avitum Ag | Dialysemaschine |
| DE102014017897A1 (de) * | 2014-12-03 | 2016-06-09 | Fresenius Medical Care Deutschland Gmbh | Peritonealdialysegerät |
| US10874787B2 (en) | 2014-12-10 | 2020-12-29 | Medtronic, Inc. | Degassing system for dialysis |
| US10098993B2 (en) | 2014-12-10 | 2018-10-16 | Medtronic, Inc. | Sensing and storage system for fluid balance |
| US9713665B2 (en) | 2014-12-10 | 2017-07-25 | Medtronic, Inc. | Degassing system for dialysis |
| US9895479B2 (en) | 2014-12-10 | 2018-02-20 | Medtronic, Inc. | Water management system for use in dialysis |
| US20160303318A1 (en) * | 2015-04-16 | 2016-10-20 | Flowonix Medical Incorporated | Implantable Drug Delivery Device with Flow Measuring Capabilities |
| US12329892B2 (en) | 2016-04-04 | 2025-06-17 | Mozarc Medical Us Llc | Dextrose concentration sensor for a peritoneal dialysis system |
| US10994064B2 (en) | 2016-08-10 | 2021-05-04 | Medtronic, Inc. | Peritoneal dialysate flow path sensing |
| US10874790B2 (en) | 2016-08-10 | 2020-12-29 | Medtronic, Inc. | Peritoneal dialysis intracycle osmotic agent adjustment |
| EP3452139B1 (en) | 2016-05-06 | 2023-08-30 | Gambro Lundia AB | System for proportioning fluids |
| CA3022989C (en) | 2016-05-06 | 2025-12-02 | Gambro Lundia Ab | DISPOSABLE KIT FOR A PERITONEAL DIALYSIS SYSTEM |
| US12144790B2 (en) | 2016-05-06 | 2024-11-19 | Gambro Lundia Ab | Dialysis concentrate |
| US10758659B2 (en) * | 2016-08-10 | 2020-09-01 | Medtronic, Inc. | Peritoneal dialysis filtrate sampling and adaptive prescription |
| ES2908601T3 (es) * | 2016-08-19 | 2022-05-03 | Outset Medical Inc | Sistema y métodos de diálisis peritoneal |
| US11013843B2 (en) | 2016-09-09 | 2021-05-25 | Medtronic, Inc. | Peritoneal dialysis fluid testing system |
| DE102017000533A1 (de) * | 2017-01-11 | 2018-07-12 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zur Herstellung gebrauchsfertiger Lösungen für die Peritonealdialyse |
| DE102017110607A1 (de) * | 2017-05-16 | 2018-11-22 | Fresenius Medical Care Deutschland Gmbh | Peritonealdialysegerät |
| US11179516B2 (en) * | 2017-06-22 | 2021-11-23 | Baxter International Inc. | Systems and methods for incorporating patient pressure into medical fluid delivery |
| US12048791B2 (en) | 2017-06-24 | 2024-07-30 | Nxstage Medical, Inc. | Peritoneal dialysis fluid preparation and/or treatment devices methods and systems |
| AU2018227226A1 (en) * | 2017-10-03 | 2019-04-18 | Medtronic, Inc. | Peritoneal dialysate preparation and sensor system |
| WO2019089447A1 (en) | 2017-10-30 | 2019-05-09 | Baxter International Inc. | Dextrose concentrate for the dialysate and for disinfecting |
| WO2019086318A1 (en) | 2017-11-03 | 2019-05-09 | Gambro Lundia Ab | "method and system for providing peritoneal dialysis fluids with varying sodium concentrations" |
| US12138280B2 (en) | 2017-11-03 | 2024-11-12 | Gambro Lundia Ab | Method and system for providing peritoneal dialysis fluids with variable potassium concentrations |
| US11278654B2 (en) | 2017-12-07 | 2022-03-22 | Medtronic, Inc. | Pneumatic manifold for a dialysis system |
| US11033667B2 (en) | 2018-02-02 | 2021-06-15 | Medtronic, Inc. | Sorbent manifold for a dialysis system |
| DE102018103936A1 (de) * | 2018-02-21 | 2019-08-22 | Fresenius Medical Care Deutschland Gmbh | Dialysegerät |
| US11110215B2 (en) | 2018-02-23 | 2021-09-07 | Medtronic, Inc. | Degasser and vent manifolds for dialysis |
| US20190262526A1 (en) * | 2018-02-28 | 2019-08-29 | Nxstage Medical, Inc. | Fluid Preparation and Treatment Devices Methods and Systems |
| US11141518B2 (en) * | 2018-06-15 | 2021-10-12 | Fresenius Medical Care Holdings, Inc. | Smart connector for a medical device |
| US11806457B2 (en) | 2018-11-16 | 2023-11-07 | Mozarc Medical Us Llc | Peritoneal dialysis adequacy meaurements |
| US11806456B2 (en) | 2018-12-10 | 2023-11-07 | Mozarc Medical Us Llc | Precision peritoneal dialysis therapy based on dialysis adequacy measurements |
| US12433976B2 (en) | 2019-01-08 | 2025-10-07 | Mozarc Medical Us Llc | Bicarbonate sensor for dialysis |
| US11413386B2 (en) * | 2019-08-09 | 2022-08-16 | Fresenius Medical Care Holdings, Inc. | Volume-based priming of dialysis machines |
| US12128165B2 (en) | 2020-04-27 | 2024-10-29 | Mozarc Medical Us Llc | Dual stage degasser |
| US11771437B2 (en) * | 2020-07-07 | 2023-10-03 | Endobar Solutions Llc | Dual-pump system for delivering embolic beads or other therapeutic substances into an artery |
| EP3992982A1 (en) | 2020-10-28 | 2022-05-04 | Bellco S.r.l. | Apparatus for dialysis and communication method for a dialysis machine |
| EP4267214A1 (en) * | 2020-12-24 | 2023-11-01 | Baxter International Inc. | Peritoneal dialysis system including peristaltic pump |
| EP4052738A1 (en) * | 2021-03-05 | 2022-09-07 | Bellco S.r.l. | Peritoneal dialysis fluid from drinking water |
| CN117042823A (zh) | 2021-03-17 | 2023-11-10 | 纳科斯达格医药股份有限公司 | 药物制备装置、方法和系统 |
| US12154673B2 (en) | 2021-08-02 | 2024-11-26 | Mozarc Medical Us Llc | Artificial intelligence assisted home therapy settings for dialysis |
| US11850344B2 (en) | 2021-08-11 | 2023-12-26 | Mozarc Medical Us Llc | Gas bubble sensor |
| US12318517B2 (en) | 2021-10-25 | 2025-06-03 | Mozarc Medical Us Llc | Inline heater for a peritoneal dialysis system |
| US11965763B2 (en) | 2021-11-12 | 2024-04-23 | Mozarc Medical Us Llc | Determining fluid flow across rotary pump |
| US11944733B2 (en) | 2021-11-18 | 2024-04-02 | Mozarc Medical Us Llc | Sodium and bicarbonate control |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0544839A4 (en) * | 1990-08-20 | 1993-08-11 | Abbott Laboratories | Medical drug formulation and delivery system |
| US5591344A (en) * | 1995-02-13 | 1997-01-07 | Aksys, Ltd. | Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof |
| US5925011A (en) * | 1995-08-30 | 1999-07-20 | Baxter International Inc. | System and method for providing sterile fluids for admixed solutions in automated peritoneal dialysis |
| US6228047B1 (en) * | 1997-07-28 | 2001-05-08 | 1274515 Ontario Inc. | Method and apparatus for performing peritoneal dialysis |
| WO2000057833A1 (en) * | 1999-03-25 | 2000-10-05 | Gambro Lundia Ab | Method and supply bag for providing a medical solution |
| SE9901165D0 (sv) * | 1999-03-30 | 1999-03-30 | Gambro Lundia Ab | Method, apparatus and components of dialysis systems |
| US7198611B2 (en) * | 2002-02-11 | 2007-04-03 | Baxter International Inc. | Dialysis connector and cap having an integral disinfectant |
| US7053059B2 (en) * | 2003-07-25 | 2006-05-30 | Baxter International Inc. | Dialysis solutions with reduced levels of glucose degradation products |
| JP4848642B2 (ja) * | 2005-02-09 | 2011-12-28 | 株式会社ジェイ・エム・エス | 腹膜灌流装置とその駆動プログラム |
| US8092414B2 (en) | 2005-11-09 | 2012-01-10 | Nxstage Medical, Inc. | Diaphragm pressure pod for medical fluids |
| JP5378203B2 (ja) * | 2006-04-07 | 2013-12-25 | ネクステージ メディカル インコーポレイテッド | 医療用の流体を作るろ過システム |
| EP2586472B1 (en) * | 2006-04-14 | 2017-08-16 | DEKA Products Limited Partnership | System for fluid pumping |
| US8870811B2 (en) * | 2006-08-31 | 2014-10-28 | Fresenius Medical Care Holdings, Inc. | Peritoneal dialysis systems and related methods |
| US8858787B2 (en) * | 2007-10-22 | 2014-10-14 | Baxter International Inc. | Dialysis system having non-invasive fluid velocity sensing |
| JP2009139091A (ja) * | 2007-12-03 | 2009-06-25 | Kurita Water Ind Ltd | 液体流計測方法および液体流計測システム |
| AU2008354310B2 (en) * | 2008-04-01 | 2014-02-20 | Gambro Lundia Ab | An apparatus and a method for monitoring a vascular access |
-
2012
- 2012-09-23 JP JP2015503186A patent/JP6407856B2/ja active Active
- 2012-09-23 EP EP18215332.0A patent/EP3482786B1/en active Active
- 2012-09-23 EP EP17170151.9A patent/EP3222306B1/en active Active
- 2012-09-23 EP EP12871735.2A patent/EP2827916B1/en active Active
- 2012-09-23 DE DE112012006079.2T patent/DE112012006079T5/de not_active Withdrawn
- 2012-09-23 WO PCT/US2012/056781 patent/WO2013141896A1/en not_active Ceased
- 2012-09-23 EP EP17170146.9A patent/EP3222305B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015517834A (ja) | 2015-06-25 |
| EP2827916B1 (en) | 2017-08-09 |
| JP6407856B2 (ja) | 2018-10-17 |
| EP2827916A4 (en) | 2015-11-18 |
| EP2827916A1 (en) | 2015-01-28 |
| EP3222305B1 (en) | 2019-01-02 |
| EP3482786A1 (en) | 2019-05-15 |
| EP3222306A1 (en) | 2017-09-27 |
| EP3222306B1 (en) | 2018-11-14 |
| WO2013141896A1 (en) | 2013-09-26 |
| EP3482786B1 (en) | 2023-12-13 |
| EP3222305A1 (en) | 2017-09-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE112012006079T5 (de) | Peritonealdialyse-Systeme, -Vorrichtungen und -Verfahren | |
| DE112012001381T5 (de) | Peritoneal-Dialyse-Systeme, -Vorrichtungen und -Verfahren | |
| EP2726120B1 (de) | Peritonealdialysemaschine | |
| US9861733B2 (en) | Peritoneal dialysis systems, devices, and methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee | ||
| R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |
Effective date: 20150401 |