DE102007010252B4 - Kontrollgene zur Normalisierung von Genexpressionsanalysedaten - Google Patents

Kontrollgene zur Normalisierung von Genexpressionsanalysedaten Download PDF

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Publication number
DE102007010252B4
DE102007010252B4 DE102007010252A DE102007010252A DE102007010252B4 DE 102007010252 B4 DE102007010252 B4 DE 102007010252B4 DE 102007010252 A DE102007010252 A DE 102007010252A DE 102007010252 A DE102007010252 A DE 102007010252A DE 102007010252 B4 DE102007010252 B4 DE 102007010252B4
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DE
Germany
Prior art keywords
control
nucleic acids
gene
seq
gene expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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DE102007010252A
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German (de)
English (en)
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DE102007010252A8 (de
DE102007010252A1 (de
Inventor
PD Dr. Rußwurm Stefan
Prof. Saluz Hans Peter
Prof. Deigner Hans-Peter
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SIRS Lab GmbH
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SIRS Lab GmbH
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Publication date
Priority to DE102007010252A priority Critical patent/DE102007010252B4/de
Application filed by SIRS Lab GmbH filed Critical SIRS Lab GmbH
Priority to EP08716110A priority patent/EP2118315B1/de
Priority to ES10196834.5T priority patent/ES2524643T3/es
Priority to CA002679017A priority patent/CA2679017A1/en
Priority to PCT/EP2008/001582 priority patent/WO2008107114A2/de
Priority to JP2009551137A priority patent/JP5430407B2/ja
Priority to US12/529,423 priority patent/US8338099B2/en
Priority to DE502008002136T priority patent/DE502008002136D1/de
Priority to ES08716110T priority patent/ES2358182T3/es
Priority to EP10196834.5A priority patent/EP2392668B1/de
Priority to AT08716110T priority patent/ATE493517T1/de
Publication of DE102007010252A1 publication Critical patent/DE102007010252A1/de
Publication of DE102007010252A8 publication Critical patent/DE102007010252A8/de
Application granted granted Critical
Publication of DE102007010252B4 publication Critical patent/DE102007010252B4/de
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE102007010252A 2007-03-02 2007-03-02 Kontrollgene zur Normalisierung von Genexpressionsanalysedaten Expired - Fee Related DE102007010252B4 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DE102007010252A DE102007010252B4 (de) 2007-03-02 2007-03-02 Kontrollgene zur Normalisierung von Genexpressionsanalysedaten
ES08716110T ES2358182T3 (es) 2007-03-02 2008-02-28 Genes de control para la normalización de datos de análisis de la expresión génica.
CA002679017A CA2679017A1 (en) 2007-03-02 2008-02-28 Reference genes for the normalization of gene expression analysis data
PCT/EP2008/001582 WO2008107114A2 (de) 2007-03-02 2008-02-28 Kontrollgene zur normalisierung von genexpressionsanalysedaten
JP2009551137A JP5430407B2 (ja) 2007-03-02 2008-02-28 遺伝子発現分析データの正規化のための参照遺伝子
US12/529,423 US8338099B2 (en) 2007-03-02 2008-02-28 Reference genes for the normalization of gene expression analysis data
EP08716110A EP2118315B1 (de) 2007-03-02 2008-02-28 Kontrollgene zur normalisierung von genexpressionsanalysedaten
ES10196834.5T ES2524643T3 (es) 2007-03-02 2008-02-28 Genes control para la normalización de datos de análisis de expresión génica
EP10196834.5A EP2392668B1 (de) 2007-03-02 2008-02-28 Kontrollgene zur Normalisierung von Genexpressionsanalysedaten
AT08716110T ATE493517T1 (de) 2007-03-02 2008-02-28 Kontrollgene zur normalisierung von genexpressionsanalysedaten
DE502008002136T DE502008002136D1 (de) 2007-03-02 2008-02-28 Kontrollgene zur normalisierung von genexpressionsanalysedaten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102007010252A DE102007010252B4 (de) 2007-03-02 2007-03-02 Kontrollgene zur Normalisierung von Genexpressionsanalysedaten

Publications (3)

Publication Number Publication Date
DE102007010252A1 DE102007010252A1 (de) 2008-09-04
DE102007010252A8 DE102007010252A8 (de) 2008-12-11
DE102007010252B4 true DE102007010252B4 (de) 2013-07-04

Family

ID=39670079

Family Applications (2)

Application Number Title Priority Date Filing Date
DE102007010252A Expired - Fee Related DE102007010252B4 (de) 2007-03-02 2007-03-02 Kontrollgene zur Normalisierung von Genexpressionsanalysedaten
DE502008002136T Active DE502008002136D1 (de) 2007-03-02 2008-02-28 Kontrollgene zur normalisierung von genexpressionsanalysedaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE502008002136T Active DE502008002136D1 (de) 2007-03-02 2008-02-28 Kontrollgene zur normalisierung von genexpressionsanalysedaten

Country Status (8)

Country Link
US (1) US8338099B2 (enrdf_load_stackoverflow)
EP (2) EP2392668B1 (enrdf_load_stackoverflow)
JP (1) JP5430407B2 (enrdf_load_stackoverflow)
AT (1) ATE493517T1 (enrdf_load_stackoverflow)
CA (1) CA2679017A1 (enrdf_load_stackoverflow)
DE (2) DE102007010252B4 (enrdf_load_stackoverflow)
ES (2) ES2524643T3 (enrdf_load_stackoverflow)
WO (1) WO2008107114A2 (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2803339C2 (ru) * 2017-12-21 2023-09-12 Спидкс Пти Лтд Определение соотношения нуклеиновых кислот

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060084082A1 (en) 1997-03-07 2006-04-20 Human Genome Sciences, Inc. 186 human secreted proteins
DE102007036678B4 (de) 2007-08-03 2015-05-21 Sirs-Lab Gmbh Verwendung von Polynukleotiden zur Erfassung von Genaktivitäten für die Unterscheidung zwischen lokaler und systemischer Infektion
DE102008000715B9 (de) * 2008-03-17 2013-01-17 Sirs-Lab Gmbh Verfahren zur in vitro Erfasssung und Unterscheidung von pathophysiologischen Zuständen
US20110076685A1 (en) * 2009-09-23 2011-03-31 Sirs-Lab Gmbh Method for in vitro detection and differentiation of pathophysiological conditions
DE102009044085A1 (de) * 2009-09-23 2011-11-17 Sirs-Lab Gmbh Verfahren zur in vitro Erfassung und Unterscheidung von pathophysiologischen Zuständen
EP2309001A1 (de) * 2009-09-23 2011-04-13 SIRS-Lab GmbH Verfahren zur in vitro Erfassung und Unterscheidung von pathophysiologischen Zuständen
PL2639312T3 (pl) * 2012-03-13 2018-01-31 Siemens Healthcare Gmbh Oznaczenie immunologiczne do wykrywania miRNA
KR102380453B1 (ko) 2014-11-26 2022-03-31 도레이 카부시키가이샤 소형 rna의 발현량의 보정 방법 및 장치
CA2986787A1 (en) 2015-05-28 2016-12-01 Immunexpress Pty Ltd Validating biomarker measurement
JP7411979B2 (ja) * 2019-07-19 2024-01-12 公立大学法人福島県立医科大学 内部標準遺伝子

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005083115A2 (de) * 2004-03-01 2005-09-09 Sirs-Lab Gmbh Verfahren zur erkennung von sepsis
DE60023496T2 (de) * 1999-05-25 2006-07-27 Aventis Pharmaceuticals Inc. Mathematische analyse für die schätzung von veränderungen des niveaus der gen-expression

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US20080070235A1 (en) * 2003-04-02 2008-03-20 Sirs-Lab Gmbh Method for Recognizing Acute Generalized Inflammatory Conditions (Sirs), Sepsis, Sepsis-Like Conditions and Systemic Infections
DE10336511A1 (de) * 2003-08-08 2005-02-24 Sirs-Lab Gmbh Verfahren zur Erkennung von schwerer Sepsis
US7587279B2 (en) * 2004-07-06 2009-09-08 Genomic Health Method for quantitative PCR data analysis system (QDAS)
JP2006170670A (ja) * 2004-12-13 2006-06-29 Sony Corp 遺伝子発現量規格化方法、プログラム、並びにシステム
US20060136145A1 (en) * 2004-12-20 2006-06-22 Kuo-Jang Kao Universal reference standard for normalization of microarray gene expression profiling data

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60023496T2 (de) * 1999-05-25 2006-07-27 Aventis Pharmaceuticals Inc. Mathematische analyse für die schätzung von veränderungen des niveaus der gen-expression
WO2005083115A2 (de) * 2004-03-01 2005-09-09 Sirs-Lab Gmbh Verfahren zur erkennung von sepsis

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Chemical Abstract AN 146:435738. In: Acta Medica Nagasakiensia, 51, 2006, 2, 57-63. *
Medline Abstract AN 2004 545 916. In: Journal of Biotechnology, 114, 2004, 1-2, 121-124. *
Medline Abstract AN 2006 143 439. In: Nutrition (Burbank, Los Angeles, Calif.), 22, 2006, 4, 408-413. *
Medline Abstract AN 2006 228 769. In: Journal of Pineal Research, 40, 2006, 4, 305-311. *
Thomas D. Schmittgen, Brian A. Zakrajsek: Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR. In: J. Biochem. Biophys. Methods, 46, 2000, 69-81. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2803339C2 (ru) * 2017-12-21 2023-09-12 Спидкс Пти Лтд Определение соотношения нуклеиновых кислот

Also Published As

Publication number Publication date
US8338099B2 (en) 2012-12-25
ATE493517T1 (de) 2011-01-15
EP2392668A2 (de) 2011-12-07
JP5430407B2 (ja) 2014-02-26
DE102007010252A8 (de) 2008-12-11
EP2392668A3 (de) 2012-05-30
EP2118315B1 (de) 2010-12-29
ES2524643T3 (es) 2014-12-10
US20100184608A1 (en) 2010-07-22
DE502008002136D1 (de) 2011-02-10
EP2118315A2 (de) 2009-11-18
WO2008107114A3 (de) 2008-11-20
ES2358182T3 (es) 2011-05-06
EP2392668B1 (de) 2014-10-29
CA2679017A1 (en) 2008-09-12
JP2010519893A (ja) 2010-06-10
DE102007010252A1 (de) 2008-09-04
WO2008107114A2 (de) 2008-09-12

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