DE102004046933A1 - Verfahren zur fermentativen Herstellung von L-Valin sowie dafür geeigneter Mikroorganismus - Google Patents

Verfahren zur fermentativen Herstellung von L-Valin sowie dafür geeigneter Mikroorganismus Download PDF

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Publication number
DE102004046933A1
DE102004046933A1 DE102004046933A DE102004046933A DE102004046933A1 DE 102004046933 A1 DE102004046933 A1 DE 102004046933A1 DE 102004046933 A DE102004046933 A DE 102004046933A DE 102004046933 A DE102004046933 A DE 102004046933A DE 102004046933 A1 DE102004046933 A1 DE 102004046933A1
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DE
Germany
Prior art keywords
genes
gene
transaminase
subunit
atp synthase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102004046933A
Other languages
German (de)
English (en)
Inventor
Jan Marienhagen
Lothar Dr. Eggeling
Hermann Prof. Dr. Sahm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forschungszentrum Juelich GmbH
Original Assignee
Forschungszentrum Juelich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich GmbH filed Critical Forschungszentrum Juelich GmbH
Priority to DE102004046933A priority Critical patent/DE102004046933A1/de
Priority to EP05779612A priority patent/EP1812553B1/de
Priority to ES05779612T priority patent/ES2320247T3/es
Priority to PCT/DE2005/001465 priority patent/WO2006034667A2/de
Priority to PT05779612T priority patent/PT1812553E/pt
Priority to DE502005006585T priority patent/DE502005006585D1/de
Priority to JP2007532758A priority patent/JP2008514191A/ja
Priority to US11/663,984 priority patent/US8158390B2/en
Priority to AT05779612T priority patent/ATE422211T1/de
Priority to DK05779612T priority patent/DK1812553T3/da
Publication of DE102004046933A1 publication Critical patent/DE102004046933A1/de
Priority to ZA200702471A priority patent/ZA200702471B/xx
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE102004046933A 2004-09-28 2004-09-28 Verfahren zur fermentativen Herstellung von L-Valin sowie dafür geeigneter Mikroorganismus Withdrawn DE102004046933A1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DE102004046933A DE102004046933A1 (de) 2004-09-28 2004-09-28 Verfahren zur fermentativen Herstellung von L-Valin sowie dafür geeigneter Mikroorganismus
DE502005006585T DE502005006585D1 (de) 2004-09-28 2005-08-19 Verfahren zur fermentativen herstellung von l-valin unter verwendung coryneformer bakterien mit erhöhter transaminase c aktivität
ES05779612T ES2320247T3 (es) 2004-09-28 2005-08-19 Procedimiento para la produccion de l-valina por fermentacion mediando utilizacion de bacterias corineformes con una actividad aumentada de transaminasa.
PCT/DE2005/001465 WO2006034667A2 (de) 2004-09-28 2005-08-19 Verfahren zur fermentativen herstellung von l-valin unter verwendung eines corynebacterium glutamicum stammes mit erhöhter transaminase c aktivität
PT05779612T PT1812553E (pt) 2004-09-28 2005-08-19 Processo para a produção de l-valina por fermentação, utilizando bactérias com actividade da transaminase c aumentada
EP05779612A EP1812553B1 (de) 2004-09-28 2005-08-19 Verfahren zur fermentativen herstellung von l-valin unter verwendung coryneformer bakterien mit erhöhter transaminase c aktivität
JP2007532758A JP2008514191A (ja) 2004-09-28 2005-08-19 増加したトランスアミナーゼｃ活性を有するコリネバクテリウム・グルタミカム株を使用するｌ−バリンの発酵的製造方法。
US11/663,984 US8158390B2 (en) 2004-09-28 2005-08-19 Method for the fermentative production of L-valine and suitable microorganism
AT05779612T ATE422211T1 (de) 2004-09-28 2005-08-19 Verfahren zur fermentativen herstellung von l- valin unter verwendung coryneformer bakterien mit erhöhter transaminase c aktivität
DK05779612T DK1812553T3 (da) 2004-09-28 2005-08-19 Fremgangsmåde til fermentativ fremstilling af L valin under anvendelse af coryneforme bakterier med foröget transaminase C-aktivitet
ZA200702471A ZA200702471B (en) 2004-09-28 2007-03-26 Method for the fermentative production of L-valine using a corynebacterium glutamicum having increased transaminase C activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004046933A DE102004046933A1 (de) 2004-09-28 2004-09-28 Verfahren zur fermentativen Herstellung von L-Valin sowie dafür geeigneter Mikroorganismus

Publications (1)

Publication Number Publication Date
DE102004046933A1 true DE102004046933A1 (de) 2006-03-30

Family

ID=35985363

Family Applications (2)

Application Number Title Priority Date Filing Date
DE102004046933A Withdrawn DE102004046933A1 (de) 2004-09-28 2004-09-28 Verfahren zur fermentativen Herstellung von L-Valin sowie dafür geeigneter Mikroorganismus
DE502005006585T Active DE502005006585D1 (de) 2004-09-28 2005-08-19 Verfahren zur fermentativen herstellung von l-valin unter verwendung coryneformer bakterien mit erhöhter transaminase c aktivität

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE502005006585T Active DE502005006585D1 (de) 2004-09-28 2005-08-19 Verfahren zur fermentativen herstellung von l-valin unter verwendung coryneformer bakterien mit erhöhter transaminase c aktivität

Country Status (10)

Country Link
US (1) US8158390B2 (pt)
EP (1) EP1812553B1 (pt)
JP (1) JP2008514191A (pt)
AT (1) ATE422211T1 (pt)
DE (2) DE102004046933A1 (pt)
DK (1) DK1812553T3 (pt)
ES (1) ES2320247T3 (pt)
PT (1) PT1812553E (pt)
WO (1) WO2006034667A2 (pt)
ZA (1) ZA200702471B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1860193A1 (en) * 2006-05-22 2007-11-28 Evonik Degussa GmbH Promoter-activity modulation for branched-chain amino acid production

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100832740B1 (ko) * 2007-01-17 2008-05-27 한국과학기술원 분지쇄 아미노산 생성능이 개선된 변이 미생물 및 이를이용한 분지쇄 아미노산의 제조방법
BR112014003249A2 (pt) 2011-08-22 2017-03-01 Res Inst Of Innovative Tech For The Earth transformante obtenível por introduzir um ou mais dos seguintes dnas (a), (b), e (c) em uma bactéria corineforme como uma hospedeira, corynebacterium glutamicum val4 (número de acesso: nite bp-1122) processo para produção de valina
EP2578559A1 (en) * 2011-10-07 2013-04-10 Metabolic Explorer Process for producing isobutene from isobutylamine
CN113913478B (zh) * 2021-11-26 2023-06-02 江南大学 一种发酵黄色短杆菌产l-缬氨酸的方法
KR20240108882A (ko) * 2022-12-30 2024-07-10 씨제이제일제당 (주) 신규한 폴리뉴클레오티드 및 이를 이용한 l-알라닌 생산 방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0913466A2 (en) * 1997-10-29 1999-05-06 Ajinomoto Co., Ltd. Method for producing L-leucine
DE10063314A1 (de) * 2000-12-20 2002-07-04 Degussa Neue für das ilvE-Gen kodierende Nukleotidsequenzen
EP1275729A1 (en) * 2000-03-24 2003-01-15 Kyowa Hakko Kogyo Co., Ltd. Process for producing l-amino acid via fermentation method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2748418B2 (ja) * 1988-08-03 1998-05-06 味の素株式会社 組換えｄｎａ、該組換えｄｎａを有する微生物
JPH05344893A (ja) * 1992-06-12 1993-12-27 Mitsubishi Petrochem Co Ltd アセトヒドロキシ酸シンターゼをコードする遺伝子ｄｎａ及びその利用
JPH0889249A (ja) * 1994-09-29 1996-04-09 Mitsubishi Chem Corp ジヒドロキシ酸デヒドラターゼをコードする遺伝子を含むｄｎａ断片
DE19907567B4 (de) * 1999-02-22 2007-08-09 Forschungszentrum Jülich GmbH Verfahren zur mikrobiellen Herstellung von L-Valin

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0913466A2 (en) * 1997-10-29 1999-05-06 Ajinomoto Co., Ltd. Method for producing L-leucine
EP1275729A1 (en) * 2000-03-24 2003-01-15 Kyowa Hakko Kogyo Co., Ltd. Process for producing l-amino acid via fermentation method
DE10063314A1 (de) * 2000-12-20 2002-07-04 Degussa Neue für das ilvE-Gen kodierende Nukleotidsequenzen

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
82:13771
97: 3341
BIOSIS Prev 198784107652 *
Chemical Abstracts: 140:58482 *
Chemical Abstracts: 82:13771 *
Chemical Abstracts: 97: 3341 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1860193A1 (en) * 2006-05-22 2007-11-28 Evonik Degussa GmbH Promoter-activity modulation for branched-chain amino acid production

Also Published As

Publication number Publication date
PT1812553E (pt) 2009-05-07
WO2006034667A2 (de) 2006-04-06
ES2320247T3 (es) 2009-05-20
EP1812553B1 (de) 2009-02-04
EP1812553A2 (de) 2007-08-01
DE502005006585D1 (de) 2009-03-19
DK1812553T3 (da) 2009-04-20
US20080153139A1 (en) 2008-06-26
US8158390B2 (en) 2012-04-17
ZA200702471B (en) 2009-01-28
WO2006034667A3 (de) 2006-07-20
JP2008514191A (ja) 2008-05-08
ATE422211T1 (de) 2009-02-15

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