DE07725949T1 - Monoklonale anti-annexin-a3-antikörper zum nachweis von prostatakrebs - Google Patents
Monoklonale anti-annexin-a3-antikörper zum nachweis von prostatakrebs Download PDFInfo
- Publication number
- DE07725949T1 DE07725949T1 DE07725949T DE07725949T DE07725949T1 DE 07725949 T1 DE07725949 T1 DE 07725949T1 DE 07725949 T DE07725949 T DE 07725949T DE 07725949 T DE07725949 T DE 07725949T DE 07725949 T1 DE07725949 T1 DE 07725949T1
- Authority
- DE
- Germany
- Prior art keywords
- antibody
- annexin
- tgc
- seq
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010060862 Prostate cancer Diseases 0.000 title claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 title claims 3
- 238000001514 detection method Methods 0.000 title 1
- 102000004120 Annexin A3 Human genes 0.000 claims abstract 13
- 108090000670 Annexin A3 Proteins 0.000 claims abstract 13
- 238000000034 method Methods 0.000 claims abstract 10
- 206010028980 Neoplasm Diseases 0.000 claims abstract 6
- 201000011510 cancer Diseases 0.000 claims abstract 6
- 230000009260 cross reactivity Effects 0.000 claims abstract 6
- 102000000412 Annexin Human genes 0.000 claims abstract 4
- 108050008874 Annexin Proteins 0.000 claims abstract 4
- 101000924454 Homo sapiens Annexin A3 Proteins 0.000 claims 3
- 238000003745 diagnosis Methods 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 210000004408 hybridoma Anatomy 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4718—Lipocortins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81208906P | 2006-06-09 | 2006-06-09 | |
| US812089P | 2006-06-09 | ||
| US85948906P | 2006-11-17 | 2006-11-17 | |
| US859489P | 2006-11-17 | ||
| PCT/EP2007/005134 WO2007141043A2 (en) | 2006-06-09 | 2007-06-11 | Monoclonal anti-annexin a3 antibodies for the detection of prostate carcinoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE07725949T1 true DE07725949T1 (de) | 2009-07-02 |
Family
ID=38653814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE07725949T Pending DE07725949T1 (de) | 2006-06-09 | 2007-06-11 | Monoklonale anti-annexin-a3-antikörper zum nachweis von prostatakrebs |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8012697B2 (enExample) |
| EP (1) | EP2024748B1 (enExample) |
| JP (1) | JP2009540278A (enExample) |
| KR (1) | KR20090023372A (enExample) |
| AU (1) | AU2007256377B2 (enExample) |
| CA (1) | CA2654330A1 (enExample) |
| DE (1) | DE07725949T1 (enExample) |
| DK (1) | DK2024748T3 (enExample) |
| ES (1) | ES2396730T3 (enExample) |
| PL (1) | PL2024748T3 (enExample) |
| PT (1) | PT2024748E (enExample) |
| RU (1) | RU2467335C2 (enExample) |
| WO (1) | WO2007141043A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1724586A3 (en) * | 2005-05-21 | 2007-07-04 | ProteoSys AG | Annexin for cancer risk assessment |
| JP2012503634A (ja) * | 2008-09-26 | 2012-02-09 | プロテオシス アクチエンゲゼルシャフト | 天然のアネキシンａ３を認識する新規抗体 |
| FR2968767B1 (fr) | 2010-12-08 | 2012-12-21 | Biomerieux Sa | Procede et coffret pour le diagnostic in vitro du cancer de la prostate |
| WO2013076222A1 (en) | 2011-11-23 | 2013-05-30 | Proteosys Ag | Differential annexin a3 measurements of serum and blood derivatives or fractions thereof for the diagnosis of prostate cancer |
| FR2991777B1 (fr) * | 2012-06-07 | 2015-08-21 | Biomerieux Sa | Procede de detection et/ou de dosage de l'annexine a3 d'un mammifere dans le sang ou au moins un de ses derives |
| US9487831B2 (en) * | 2013-09-12 | 2016-11-08 | Versitech Limited | Use of annexin A3 as a diagnostic and prognostic biomarker and therapeutic target for treating hepatocellular carcinoma |
| US9470677B2 (en) | 2013-11-28 | 2016-10-18 | Samsung Electronics Co., Ltd. | Cell with surface coated with ANXA1 and use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4104910C3 (de) | 1991-02-18 | 2000-02-24 | Schloemann Siemag Ag | Stahlnachbehandlungsanlage |
| US5136855A (en) | 1991-03-05 | 1992-08-11 | Ontario Hydro | Heat pump having an accumulator with refrigerant level sensor |
| US20030108963A1 (en) * | 2001-07-25 | 2003-06-12 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer |
| DE10217254A1 (de) | 2002-04-15 | 2003-10-23 | Proteosys Ag | Verwendung von Substanzen zur Behandlung von Tumoren |
| JP5068543B2 (ja) * | 2004-02-16 | 2012-11-07 | プロテオジス アクチェンゲゼルシャフト | がんに関する診断マーカー |
| EP1724585A1 (en) * | 2005-05-21 | 2006-11-22 | ProteoSys AG | Annexin for cancer risk assessment |
| EP1724586A3 (en) | 2005-05-21 | 2007-07-04 | ProteoSys AG | Annexin for cancer risk assessment |
-
2007
- 2007-06-11 DK DK07725949.7T patent/DK2024748T3/da active
- 2007-06-11 JP JP2009513608A patent/JP2009540278A/ja not_active Ceased
- 2007-06-11 PL PL07725949T patent/PL2024748T3/pl unknown
- 2007-06-11 EP EP07725949A patent/EP2024748B1/en active Active
- 2007-06-11 ES ES07725949T patent/ES2396730T3/es active Active
- 2007-06-11 RU RU2008152009/15A patent/RU2467335C2/ru not_active IP Right Cessation
- 2007-06-11 DE DE07725949T patent/DE07725949T1/de active Pending
- 2007-06-11 US US12/303,825 patent/US8012697B2/en not_active Expired - Fee Related
- 2007-06-11 KR KR1020087029969A patent/KR20090023372A/ko not_active Ceased
- 2007-06-11 PT PT77259497T patent/PT2024748E/pt unknown
- 2007-06-11 CA CA002654330A patent/CA2654330A1/en not_active Abandoned
- 2007-06-11 WO PCT/EP2007/005134 patent/WO2007141043A2/en not_active Ceased
- 2007-06-11 AU AU2007256377A patent/AU2007256377B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007141043A3 (en) | 2008-03-20 |
| EP2024748B1 (en) | 2012-12-12 |
| WO2007141043A2 (en) | 2007-12-13 |
| RU2467335C2 (ru) | 2012-11-20 |
| US8012697B2 (en) | 2011-09-06 |
| AU2007256377A1 (en) | 2007-12-13 |
| US20100233160A1 (en) | 2010-09-16 |
| JP2009540278A (ja) | 2009-11-19 |
| ES2396730T3 (es) | 2013-02-25 |
| EP2024748A2 (en) | 2009-02-18 |
| CA2654330A1 (en) | 2007-12-13 |
| AU2007256377B2 (en) | 2012-11-01 |
| PL2024748T3 (pl) | 2013-05-31 |
| KR20090023372A (ko) | 2009-03-04 |
| PT2024748E (pt) | 2013-01-16 |
| DK2024748T3 (da) | 2013-03-18 |
| RU2008152009A (ru) | 2010-07-20 |
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