DD228547A5 - Verfahren zur herstellung von neuen amid-verbindungen - Google Patents

Verfahren zur herstellung von neuen amid-verbindungen Download PDF

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Publication number
DD228547A5
DD228547A5 DD84269486A DD26948684A DD228547A5 DD 228547 A5 DD228547 A5 DD 228547A5 DD 84269486 A DD84269486 A DD 84269486A DD 26948684 A DD26948684 A DD 26948684A DD 228547 A5 DD228547 A5 DD 228547A5
Authority
DD
German Democratic Republic
Prior art keywords
phenyl
lower alkyl
substituted
formula
alkyl
Prior art date
Application number
DD84269486A
Other languages
German (de)
English (en)
Inventor
Bruno Kamber
Thomas Leutert
Hans Kuehnis
Kurt Eichenberger
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DD228547A5 publication Critical patent/DD228547A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD84269486A 1983-11-16 1984-11-14 Verfahren zur herstellung von neuen amid-verbindungen DD228547A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH615483 1983-11-16
CH342584 1984-07-13

Publications (1)

Publication Number Publication Date
DD228547A5 true DD228547A5 (de) 1985-10-16

Family

ID=25692968

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84269486A DD228547A5 (de) 1983-11-16 1984-11-14 Verfahren zur herstellung von neuen amid-verbindungen

Country Status (13)

Country Link
EP (1) EP0145956A1 (no)
KR (1) KR850003713A (no)
AU (1) AU578633B2 (no)
DD (1) DD228547A5 (no)
DK (1) DK543084A (no)
ES (4) ES8706634A1 (no)
FI (1) FI844466L (no)
GR (1) GR80948B (no)
HU (1) HU193909B (no)
IL (1) IL73509A (no)
NO (1) NO844560L (no)
NZ (1) NZ210223A (no)
PT (1) PT79498B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994476A (en) * 1984-10-31 1991-02-19 Bristol-Myers Company Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties
JPH0676405B2 (ja) * 1986-06-13 1994-09-28 日清製粉株式会社 1,4―ジヒドロピリジン誘導体およびそれを含有する医薬組成物
US4808603A (en) * 1985-08-14 1989-02-28 Ciba-Geigy Corporation 3,5-diacyl-2,6-dialkyl-4-aryl-1,4-dihydropyridines, their use, and pharmaceutical compositions thereof
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
EP0488345B1 (en) * 1990-11-30 1999-07-14 Fujirebio Inc. Optically active 1,4-Dihydropyridine derivatives and methods of producing the same
EP0536671B1 (de) * 1991-10-07 1996-03-06 Hoechst Aktiengesellschaft Carbonsäureester-Schutzgruppen, ein Verfahren zu ihrer Herstellung, ihre Kopplung an eine funktionelle Gruppe sowie ihre Verwendung
US6593335B1 (en) * 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
US6265417B1 (en) 1997-12-18 2001-07-24 Abbott Laboratories Potassium channel openers
CN107857712B (zh) * 2016-09-22 2022-09-09 烟台益诺依生物医药科技有限公司 (r)-3-甲基-2-(3-氧代酰胺基)正丁酸酯

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
DE3042769A1 (de) * 1980-11-13 1982-06-09 Bayer Ag, 5090 Leverkusen C-3 verknuepfte 1,4-dihydropyridine, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
FR2508446B1 (fr) * 1981-06-25 1986-05-02 Rhone Poulenc Agrochimie Herbicides a fonctions amide et ester derives de la pyridine ainsi que leur procede de preparation et leur application
EP0111453A1 (de) * 1982-12-10 1984-06-20 Ciba-Geigy Ag Amid-Verbindungen
DE3319956A1 (de) * 1983-06-01 1984-12-06 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US4755512A (en) * 1984-04-11 1988-07-05 Bristol-Myers Company Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities

Also Published As

Publication number Publication date
ES550926A0 (es) 1987-02-16
IL73509A0 (en) 1985-02-28
ES550927A0 (es) 1987-02-16
AU3547484A (en) 1985-05-23
ES8703428A1 (es) 1987-02-16
FI844466L (fi) 1985-05-17
HUT35645A (en) 1985-07-29
NO844560L (no) 1985-05-20
DK543084D0 (da) 1984-11-15
IL73509A (en) 1988-05-31
PT79498B (en) 1987-01-13
NZ210223A (en) 1988-10-28
FI844466A0 (fi) 1984-11-14
ES550928A0 (es) 1987-02-16
AU578633B2 (en) 1988-11-03
GR80948B (en) 1985-03-01
PT79498A (en) 1984-12-01
ES537646A0 (es) 1987-06-16
ES8706634A1 (es) 1987-06-16
ES8703424A1 (es) 1987-02-16
EP0145956A1 (de) 1985-06-26
DK543084A (da) 1985-05-17
KR850003713A (ko) 1985-06-26
HU193909B (en) 1987-12-28
ES8703427A1 (es) 1987-02-16

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