CZ39093A3 - Oligosaccharide and pharmaceutical preparation in which it is comprised - Google Patents

Oligosaccharide and pharmaceutical preparation in which it is comprised Download PDF

Info

Publication number
CZ39093A3
CZ39093A3 CZ93390A CZ39093A CZ39093A3 CZ 39093 A3 CZ39093 A3 CZ 39093A3 CZ 93390 A CZ93390 A CZ 93390A CZ 39093 A CZ39093 A CZ 39093A CZ 39093 A3 CZ39093 A3 CZ 39093A3
Authority
CZ
Czechia
Prior art keywords
glcnac
mana
fuca
cells
oligosaccharides
Prior art date
Application number
CZ93390A
Other languages
Czech (cs)
English (en)
Inventor
Betty Yan Sau-Chi Ph D
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CZ39093A3 publication Critical patent/CZ39093A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Amplifiers (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
CZ93390A 1992-03-12 1993-03-10 Oligosaccharide and pharmaceutical preparation in which it is comprised CZ39093A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84986892A 1992-03-12 1992-03-12

Publications (1)

Publication Number Publication Date
CZ39093A3 true CZ39093A3 (en) 1994-03-16

Family

ID=25306715

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ93390A CZ39093A3 (en) 1992-03-12 1993-03-10 Oligosaccharide and pharmaceutical preparation in which it is comprised

Country Status (23)

Country Link
EP (1) EP0565241B1 (es)
JP (1) JP3171506B2 (es)
KR (1) KR930019696A (es)
CN (1) CN1079967A (es)
AT (1) ATE137241T1 (es)
AU (1) AU661762B2 (es)
BR (1) BR9301136A (es)
CA (1) CA2091521A1 (es)
CY (1) CY1947A (es)
CZ (1) CZ39093A3 (es)
DE (1) DE69302317T2 (es)
DK (1) DK0565241T3 (es)
ES (1) ES2088227T3 (es)
FI (1) FI931086A (es)
GR (1) GR3020406T3 (es)
HK (1) HK132396A (es)
HU (1) HUT69613A (es)
IL (1) IL105018A0 (es)
MX (1) MX9301344A (es)
NO (1) NO930890L (es)
NZ (1) NZ247105A (es)
YU (1) YU16993A (es)
ZA (1) ZA931723B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60235231D1 (de) * 2001-04-02 2010-03-18 Glycomedics Inc Verfahren zur herstellung von oligosaccharidketten
FI20011664A (fi) 2001-08-17 2003-02-18 Carbion Oy Syöpäpesifiset oligoskkaridisekvenssit ja niiden käyttö
US7943763B2 (en) * 2002-07-05 2011-05-17 Otsuka Chemical Holdings Co., Ltd. Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides
KR100661212B1 (ko) * 2002-12-26 2007-04-16 오츠카 가가쿠 가부시키가이샤 3분지형 당사슬 아스파라긴 유도체, 상기 당사슬아스파라긴, 상기 당사슬 및 그들의 제조방법
JP3884725B2 (ja) 2003-06-03 2007-02-21 三菱電機株式会社 導波管装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009889A (en) * 1987-12-31 1991-04-23 Oklahoma Medical Research Foundation Treatment of dysfunctional vascular endothelium using activated protein C

Also Published As

Publication number Publication date
CA2091521A1 (en) 1993-09-13
EP0565241B1 (en) 1996-04-24
HUT69613A (en) 1995-09-28
ZA931723B (en) 1994-09-10
NZ247105A (en) 1994-11-25
JP3171506B2 (ja) 2001-05-28
EP0565241A1 (en) 1993-10-13
FI931086A (fi) 1993-09-13
DK0565241T3 (da) 1996-05-28
DE69302317T2 (de) 1996-09-19
DE69302317D1 (de) 1996-05-30
AU3519993A (en) 1993-09-16
FI931086A0 (fi) 1993-03-11
ATE137241T1 (de) 1996-05-15
CY1947A (en) 1993-03-12
JPH0625302A (ja) 1994-02-01
KR930019696A (ko) 1993-10-18
MX9301344A (es) 1993-09-01
CN1079967A (zh) 1993-12-29
NO930890L (no) 1993-09-13
IL105018A0 (en) 1993-07-08
YU16993A (sh) 1996-02-19
ES2088227T3 (es) 1996-08-01
HU9300687D0 (en) 1993-05-28
GR3020406T3 (en) 1996-09-30
AU661762B2 (en) 1995-08-03
HK132396A (en) 1996-07-26
BR9301136A (pt) 1993-09-28
NO930890D0 (no) 1993-03-11

Similar Documents

Publication Publication Date Title
Yan et al. Novel Asn-linked oligosaccharides terminating in GaINAcβ (1→ 4)[Fuca (1→ 3)] GlcNAcB (1→•) are present in recombinant human Protein C expressed in human kidney 293 cells
EP1325113B1 (en) Factor vii glycoforms
Witte et al. Enzymatic glycoprotein synthesis: preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation
EP2682473B1 (en) Method for producing sialic-acid-containing sugar chain
Valley et al. Incorporation of ammonium into intracellular UDP‐activated N‐acetylhexosamines and into carbohydrate structures in glycoproteins
Brockhausen et al. Glycosyltransferase changes upon differentiation of CaCo-2 human colonic adenocarcinoma cells
Bergwerff et al. The Major N‐Linked Carbohydrate Chains from Human Urokinase: The Occurrence of 4‐O‐sulfated,(α2‐6)‐sialylated or (α1‐3)‐fucosylated N‐acetylgalactosamine (β1‐4)‐N‐acetylglucosamine Elements
AU604425B2 (en) Oligosaccharides isolated from t-pa glycoproteins
Makino et al. Structural analysis of N-linked sugar chains of human blood clotting factor IX
CZ39093A3 (en) Oligosaccharide and pharmaceutical preparation in which it is comprised
Pfeiffer et al. Carbohydrate structure of recombinant human uterine tissue plasminogen activator expressed in mouse epithelial cells
KR20160122158A (ko) 인자 vii 컨쥬게이트
Fishman et al. A comparison of membrane glycoconjugates from mouse cells transformed by murine and primate RNA sarcoma viruses
US4851517A (en) Tissue plasminogen activator oligosaccharide from normal human colon cells
HILL Glycosyltransferases in analysis of oligosaccharide structure and function
Mori et al. Isolation and characterization of endogenous ligands for liver mannan-binding protein
Böhme et al. Tyrosine sulfation and N‐glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin binding
Kuraya et al. Structural analysis of O-linked sugar chains in human blood clotting factor IX
EP0654529B1 (en) alpha-2,8-SIALYLTRANSFERASE
US20170035890A1 (en) Coagulation Factor IX Conjugates
EP0236289A2 (en) Tissue plasminogen activator from normal human colon cells
RU2325181C2 (ru) Гликоформы фактора vii
JPS62282581A (ja) ヒト正常結腸細胞由来組織プラスミノ−ゲン活性化因子
MELCHER et al. Glycosylation-site-selective synthesis of N-acetyl-lactosamine repeats in bis-glycosylated human lysozyme