CZ23342U1 - Composition to ameliorate otitis pain and to clean external acoustic meatus - Google Patents

Description

Technical field

The proposed technical solution is in the field of medical preparations of indeterminate composition, containing materials from races, lichens, fungi or plants or their derivatives.

Background Art

Excessive earwax may accumulate in the external auditory canal if the ear is not self-cleaning or if dirt (water, dust) is present. This can lead to deterioration of the ear canal, as well as conditions for overgrowth or growth of microorganisms, which may be a source of inflammation (otitis media) and other health problems.

The remedies for this negative condition are usually based on the ability to dissolve the earwax and water well in the ear canal so that the resulting solution can drain, or be removed by drying. The preparations exhibit antimicrobial components, whereby their use suppresses possible overgrowth of microorganisms and thus possible later inflammation. Antimicrobial action can be achieved in combination by using a suitable major component that dissolves the other components of the formulation, by using antibacterial agents or by adjusting appropriate properties, e.g., by reducing the pH of the formulation.

Furthermore, there are preparations which are intended to control the effects of inflammation, in particular pain relief, which essentially contain active substances with anti-inflammatory anesthetic and analgesic effects. It may be a combination of corticosteroids and substances with a local anesthetic effect (benzocaine, lidocaine, cinchocain, etc.) or non-steroidal substances and other components with analgesic effects.

A disadvantage of the hitherto known preparations is the fact that the simultaneous combined action of pain control (anesthetic), anti-inflammatory, antimicrobial and cleansing is not achieved. The combination of these effects may be advantageous in otitide therapy, particularly in the early stages and, if necessary, in conventional ear cleaning. Preparations currently used act by one or a combination of local anesthetic and anti-inflammatory, antibiotic, anti-inflammatory and anesthetic effects. In addition, due to the content of antibiotics, corticosteroids or anesthetics, preparations cannot be used for routine ear cleaning.

The essence of the technical solution

The essence of the proposed technical solution is a combination of formulation components which achieves a combined action of pain relief (anesthetic), anti-inflammatory, antimicrobial and cleansing. Thus, the preparation can be used both to remove earwax, water and impurities from the external auditory canal as well as in the early stages of otitis. The preparation contains a combination of natural and synthetic substances and is in the form of a solution. The composition consists of 10 to 60 wt. % glycerol at a concentration of 99.5% (glycerol), and from 10 to 60 wt. % Of 1,3 butanediol, also referred to as butylene glycol. The mixture of glycerol and butylene glycol exhibits a softening effect and softens and dissolves earwax and is also miscible with water. It also serves as a mixture of excipients in which other ingredients are dissolved. It co-creates an environment unsuitable for the growth of bacterial infections.

It further comprises 0.01 to 1 wt. % Of 2-isopropyl-5-methylphenol, also referred to as thymol. The thymol in the preparation acts as an antibacterial component. It complements the effects of the product, especially when water remains in the ear canal, which can create an environment suitable for microbial infections.

The composition further comprises 0.1 to 2 wt. % Lavandula Angustifolia oil, and 10 to 30 wt. % choline salicytate 80% choline salicytate. Choline salicytate has anti-inflammatory effects that supplement the effects of the product when hardened earwax, dirt, or mechanical debris removal causes skin irritation to the ear canal.

The composition further comprises 1 to 20 wt. % of herbal extract, which herbal extract consists of 80 grams of dry calendula flower Calendulae flos cum ca lyce, 50 grams of dry drug mullein Verbasci flos and 50 grams of dry drug St John's wort Hyperica games and extracted in 1000 ml of ethanol. Herbal extract helps regenerate and stimulates the self-cleaning ability of the ear canal.

Thanks to the unique combination of active ingredients, the product is particularly suitable for removing earwax, water and impurities from the external auditory canal. Ear wax dissolves after use and freely flows out of the ear canal, or is softened and then easily removable mechanically. When removing the water from the ear canal (after bath, shower, swimming, diving, etc.), the product is mixed with residual water to allow it to evaporate or leak. It is also particularly useful as a first-line agent for otitis. The advantage of the formulation is that the effects are achieved without the presence of antibiotics, corticoids or strong anesthetics.

Example of a technical solution

The preparation for relieving painful symptoms of inflammation of the ear and for cleaning the external auditory canal contains a combination of natural and synthetic substances and is in the form of a solution. The composition in this particular embodiment consists of 36.6 wt. % glycerin at a concentration of 99.5%, from 36.6 wt. % 1,3 butanediol, from 0.1 wt. % 2-isopropyl-5-methylphenol, from 1.1 wt. % Lavandula Angustifolia, from 17.4 wt. % choline salicytate 80% choline salicytate and 8.2 wt. % of herbal extract. Herbal extract consists of 80 grams of dry Calendulae flos cum calyce flower, 50 grams of dry mullein Verbasci flos flower and 50 grams of dry drug St John's wort Hyperici games, extracted in 1000 ml of ethanol.

Claims (1)

PROTECTION REQUIREMENTS 1. A composition for relieving pain in ear inflammation and for cleaning the external auditory canal, which comprises a combination of natural and synthetic substances and is in the form of a solution comprising 10 to 60 wt.% Glycerin having a concentration of 99.5%. , 30 of 10 to 60 wt. 1.3 butanediol, from 0.01 to 1 wt. % Of 2-isopropyl-5-methylphenol, from 0.1 to 2 wt. Lavandula Angustifolia oil, from 10 to 30 wt. % choline salicytate Cholin salicytate at a concentration of 80% and from 1 to 20 wt. % of the herbal extract which the herbal extract consists of 35 out of 80 grams of dry calendula flower calendulae flos cum calyce, 50 grams of dry drug flower of mullein Verbasci flos and 50 grams of dry drug topper St. John's wort extracted in 1000 ml of ethanol.