CZ20014011A3 - Antitranspirant agent - Google Patents

Abstract

The invention relates to an antiperspirant stick with a content of (A) 10-30 wt. % astringent aluminium salts, zirconium salts or zinc salts, (B) 30-50 wt. % liquid carrier components, (C) 18-30 wt. % stabilising fat or wax components and (D) 1-20 wt. % water-soluble surfactants. The antiperspirant stick is provided with an improved antiperspirant effect when the liquid carrier component contains 20-40 wt. % nonpolar oil, e.g. a liquid silicone oil, and 10-30 wt. % polar oil selected from liquid, branched alkanols, alkandioles, ether alcohols and dialkyl ethers with 12-24 C-atoms and addition products of 2-30 mol propylene oxide to monovalent or multivalent alkanols with 3-20 C-atoms respectively in relation to the entire stick mass respectively.

Description

Technical field

BACKGROUND OF THE INVENTION The present invention relates to an antitranspirant composition in the form of a water-free or water-free spreadable bar in which the antiperspirant active ingredients are dispersed in a carrier consisting of a liquid, non-polar carrier material, solid fat or wax and wetting agents.

BACKGROUND OF THE INVENTION

Various cosmetic products are available to prevent sweating and to remove body odor, one of the most suitable means for this use being sticks, since they are simple and practical. The basis for these bars must be a material with sufficient hardness and shape stability, on the other hand, the bar must be spreadable on the skin only when light pressure is applied. These requirements can be met, for example, using gel-based soap compositions based on a mixture of water and alcohol or water and glycol. Bars of this type have the disadvantage that acidic aluminum salts such as aluminum hydrochloride cannot be used.

The so-called anhydrous bars have a specific meaning. Rods of this type consist of a dispersion of fine particles of astringent aluminum or zirconium salts and a non-polar carrier liquid reinforced with waxy or fatty components. As the non-polar carrier liquid, for example, hydrocarbons or silicone oils may be used, preferably with / ♦ · ··

9 1 ·

a boiling point of less than 200 ° C or with a specific volatility, for example cyclic siloxanes such as cyclomethicone and mixtures thereof with oil components for skin softening.

Anhydrous bars of this type have the disadvantage that the sweating effect of said salts does not occur quickly enough and with sufficient intensity.

It is known to improve these products by the addition of wetting agents which can be used to hydrophilize the rod-making material and to wash the rest of the rods from the skin or clothing well. For example, US 4151272 discloses antitranspiratory sticks containing up to 5% by weight of a fatty alcohol polyglycol ether. EP 491843 B1 discloses compositions for the production of antitranspiration sticks which contain an addition product of 10 moles of propylene oxide and butanediol to prevent the Weissel effect. From EP 777463 B1 antitranspiratory sticks are known which contain 11,12-dihydroxystearic acid as a fat or wax component.

The aforementioned known materials for the manufacture of antitranspiratory sticks have various disadvantages.

These materials, which have a too low content of strengthening waxy components, tend to precipitate oil at a higher temperature. Those materials that do not contain any polar constituents in the liquid vehicle have too weak antitranspiratory activity. It has been shown that antitranspirant sticks can also be prepared with relatively high levels of fat or wax constituents with sufficient efficacy and rapid onset of action if the liquid carrier * 4 • 4

The component contains a higher proportion of polar oil components such as branched-chain liquid alkanols, alkanediols or liquid dialkyl ethers each having a chain length of 12 to 24 carbon atoms.

SUMMARY OF THE INVENTION

SUMMARY OF THE INVENTION The present invention provides an antitranspirant in the form of a stick containing astringent anti-perspiration salts dispersed in a skin-spreadable material having sufficient shape stability at 40 ° C, the composition comprising (A) 10-30% by weight aluminum astringent salts , zirconium or zinc, (B) 30 to 50% by weight of a liquid carrier component, (C) 18 to 30% by weight of a hardening fat or wax component with a melting point of 40 to 80 ° C, (D) 1 to 20% by weight of water soluble wetting agents, wherein the liquid carrier component B contains up to 40% by weight of a nonpolar oil, preferably a silicone oil which is liquid or low boiling, up to 30% by weight of a polar oil selected from branched-chain liquid alkanols, alkanedioles, ether alcohols or dialkyl ethers having a chain length of 12 to 24 carbon atoms and from 2 to 30 addition products moles of propylene oxide and mono- or polyhydric alkanols having a chain length of 3 to 20 carbon atoms.

All percentages are by weight of the antitranspirant.

to total

4

In particular, astringent or protein-coagulating aluminum, zirconium or zinc salts are used in the composition according to the invention as perspiration-inhibiting agents. Such salts are, for example, aluminum chloride, aluminum hydroxychloride, aluminum dihydrochloride, aluminum sesquichloride and complex compounds thereof, for example with 1,2-propylene glycolate, aluminum hydroxyalantoinate, mixed aluminum chloride and tartrate, aluminum sulphate, sodium lactate sodium, potassium salt aluminum sulphate (K-Alaun), aluminum and zirconium trihydrochloride, aluminum and zirconium tetrahydrochloride, aluminum and zirconium pentahydrochloride and complex compounds thereof with amino acids such as glycine may be, for example, aluminum-zirconium-tetrachlorglycine complex, zirconium lactate sodium , zinc sulfate and zinc phenolsulfonate. The astringent salts should have a small particle diameter at a mean particle size of less than 100 and preferably less than 50 microns. A particularly preferred astringent salt is aluminum hydroxy chloride of the formula Al ₂ (OH) ₅ Cl ₂ to 3 H ₂ O, used in an amount of 15 to 25% by weight.

In the case of the composition according to the invention, a rapid onset of action and high efficacy is required, and it has been shown that these properties can be achieved when the astringent salts are coated with or impregnated with a water-soluble nonionic surfactant. Particularly preferred wetting agents for this purpose are the alkyl oligoglycosides used in an amount of 0.1 to 5% by weight on the surface of the salt particles.

T t »» © © 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

As the reinforcing component or the wax component, one or more of any saturated linear fatty acid or fatty alcohol having a chain length of 14 to 22 carbon atoms, triglycerides of saturated fatty acids having a chain length of 14 to 22 carbon atoms, saturated linear esters of waxes, i.e. esters of fatty acids and fatty alcohols containing from 28 to 44 carbon atoms or mixtures thereof. A very suitable material for this use is a mixture of one part by weight of hydrogenated castor oil and two to four parts by weight of cetyl alcohol or stearyl alcohol.

As a water-soluble surfactant, any surfactant which is soluble in the system at 20 ° C in an amount of 1% by weight and any surfactant which is soluble in water at 20 ° C in an amount of 1% by weight can be used in principle. Although the structure and charge of the surfactant is not critical, nonionic surfactants, particularly ethylene oxide addition products and molecules with at least one alkoxylated group, which are solid at 20 ° C, are particularly suitable. Such suitable wetting agents include, for example, the addition products of 10 to 40 moles of ethylene oxide and linear fatty alcohols of 16 to 22 carbon atoms or fatty acids of 12 to 22 carbon atoms, fatty acid alkanolamides, fatty acid monoglycerides, sorbitan monoesters of fatty acids, e.g. o an addition product of 10 to 40 moles of ethylene oxide and a cured castor oil or a fatty acid methyl glucoside ester, or a mixture thereof.

The liquid carrier component is composed of non-polar or polar liquid oil components. The main ingredient is »« (

9

9

9 9

9 • * 999 99

9999 non-polar oil, which may be, for example, silicone oil or hydrocarbon-based oil. Linear or cyclic dimethylpolysiloxane of low boiling or volatile nature is preferred as a nonpolar oil. Particularly preferred volatile silicone oils are cyclic polydimethylsiloxanes of the formula [(CH 3) 2 SiO] _n v. N = 4, 5 or 6. Products of this type are commercially available under the trade name Dow Corning ^13200, 244, 245, 344, or 345.

The polar volatile component of the carrier component has a particularly large influence on the properties of the resulting composition, in particular on the effectiveness of the antitranspirant. These are preferably branched-chain volatile alkanols, C 12 -C 24 alkanediols, ether alcohols and dialkyl ethers or addition products of 2 to 30 moles of propylene oxide and monohydric or polyhydric alkanols having a chain length of 3 to 20 carbon atoms. It is also possible to use addition products of ethylene oxide and propylene oxide and said alkanols or polyols, for example glycerol.

The volatile branched alcohols which may be used are, for example, single branched guerbet alcohols at the 2-carbon atom, for example 2-hexyldecanol or 2-octyldodecanol. Other suitable liquid alcohols are, for example, isotridecanol, isohexadecanol and mixtures of these alcohols.

Suitable alkanediols are diols obtained from C 12 -C 24 epoxyalkanes by ring opening with water. Suitable ether alcohols are, for example, the monoalkyl ethers of glycerol, ethylene glycol,

1,2-propylene glycol or 1,2-butanediol and other products obtainable by ring opening from epoxyalkanes, when these contain 12 to 24 carbon atoms.

A suitable dialkyl ether is, for example, an alkyl methyl ether or a di-n-alkyl ether having a chain length of 12 to 24 carbon atoms. A particularly suitable di-n-alkyl ether is the commercially available product Cetiol ^R OE (Henkel KGaA), a di-n-octyl ether.

Suitable addition products of propylene oxide and monohydric or polyhydric alcohols are, for example, PPG-3-myristyl ether (Wticonol ^R APM), PPG-14-butyl ether (Ucon Fluid ^R AP), PPG-15-stearyl ether (Arlamol ^R Ε), PPG-9-butyl ether . (Breox ^R B25) or PPG-10-butanediol (Macol ^R 57).

In a preferred embodiment, the antitranspirants of the present invention contain, as a polar oil, a branched chain alkanol selected from 2-hexyldecanol, 2-octyldecanol and mixtures of these alcohols with 2 to 20 moles of propylene oxide and alkanols having a chain length of 3 to 20 carbon atoms.

In addition, the transplant compositions of the invention may contain conventional excipients and other cosmetic or dermatological active ingredients.

Of particular importance are internal, finely-powdered, inorganic or organic fillers. Such an inert filler may be, for example, silica, various clays, talc, veegum or organic fillers such as powdered polymers, starches or cellulose. Preferably, they comprise

The antitranspirants of the invention in the form of a stick of 1 to 20% by weight of a finely divided powder of the talc, silica and mixtures thereof. By using these fillers, the strength and spreadability of the resulting composition can be substantially improved.

Other conventional adjuvants used in deodorant and antitranspirant compositions are oils, perfumes, antioxidants, complexing agents, antimicrobials, esterase blocking agents, and odor absorbing polymers. Further, dyes or colored or white pigments may be added to the composition to increase the attractiveness of the resulting composition.

The following examples illustrate the invention without limiting the scope of the invention.

DETAILED DESCRIPTION OF THE INVENTION

The compositions 1 to 5, as shown in the following table, are formulated as a stick. For comparison, the bars are also prepared from comparative mixtures VI, V2, V3 and V4, which

- in the case of VI and V3 they contain a lower proportion of polar oils,

in the case of V2, they contain a lower proportion of firming or waxy firming components, or

- in the case of V4, they do not contain any water-soluble surfactant.

• ·

999 9

Antitranspiracy was investigated by the Bio Skin method of SOFW Journal, Volume 123, 10/97, pp. 639-642. A reduction in sweat formation after application for three days was determined, compared with the untreated skin area. The results were evaluated as follows:

Reduction of sweat formation: ++ very good + good - weak The bar hardness was determined after storage at 50 ° C for three days.

Hardness (50 ° C): ++ very good + satisfactory

- oily consistency, oil outlet

1 2 3 4 5 VI V2 V3 V4 Silicone oil DC ^r 245 28 28 23 23 23 38 42 47 31 Eutanol * G 16 10 - - 15 Dec 10 - 10 - 10 Cetiol * OE - 10 15 Dec - - - - - Ucon Fluid AP 5 5 5 5 5 5 5 5 5 Cutina * HR 6 6 6 6 6 6 2 5 6 Lorol * C 18 20 May 20 May 20 May - 20 May 20 May - 20 May Lanette * 0 - - - 20 May - 10 12 - Eumulgin * B 3 3 3 3 3 3 3 3 3 - Cutina E 24 PF - - - - 5 - - - - AHC 20 May 20 May 20 May 20 May 20 May 20 May 20 May 20 May 20 May Talc 8 8 8 8 8 8 8 8 8 Reduce sweat ++ ++ ++ + ++ + + + - Hardness (50 ° C, 73h) + + ++ ++ ++ ++ ++ + ++

«4 ·

44

Ο

4 »

··· 444 • 4

4 • 4

I • 4

4 »• 4

4

4 4 4

The following commercially available products have been used in the preparation of antitranspirant products:

Silicone oil DC ^R 245 Eutanol ^R G 16 Cetiol ^R OE Ucon Fluid ^R AP Cutina ^R HR Lorol ^R C 18 Lanette ^R O Eumulgin ^R B 3 Cutina ^R E 24 PF AHC (aluminumhydroxy chloride) dimethylcyclopentasiloxane 2-hexyldecanol di-n-octylether PPG- 14-butyl ether hydrogenated castor oil stearyl alcohol cetyl / stearyl alcohol 1: 1 PEG-30-cetyl / stearyl ether PEG-20-gyceryl stearate

Micro Dry ^R UF (Reheis / Interorgana)

Claims (6)

PATENT CLAIMS An antitranspirant in the form of a stick containing astringent salts to prevent sweat dispersion which is dispersed in a skin-spreadable material having sufficient shape stability at 40 ° C, the composition comprising (A) 10-30% by weight of aluminum astringent salts, (B) 30 to 50% by weight of the liquid carrier component; (C) 18 to 30% by weight of a firming fat or wax component with a melting point of 40 to 80 ° C; (D) 1 to 20% by weight of water-soluble surfactants, characterized in that the liquid carrier component B comprises: 20 to 40% by weight of a non-polar oil, preferably a silicone oil which is liquid or low boiling, 10 to 30% by weight of a polar oil selected from branched-chain liquid alkanols, alkanediols, ether alcohols or dialkyl ethers each having a chain length of 12 to 24 carbon atoms and addition products of 2 to 30 moles of propylene oxide and mono- or polyhydric alkanols having a chain length of 3 to 20 atoms carbon. An antitranspirant according to claim 1, characterized in that it contains linear or cyclic dimethyl polysiloxane, volatile or low boiling, as a nonpolar oil. An antitranspirant according to claim 1 or 2, characterized in that it contains, as a polar oil, a single branched alkanol from the group consisting of: 4 4 4 4 4 4 4 4 4 4 4 44 4 2-hexyldecanol, 2-octyldodecanol and mixtures of these alcohols with addition products of 2 to 20 moles of propylene oxide and alkanols of 3 to 20 carbon atoms. Antitranspirant according to any one of claims 1 to 3, characterized in that it contains saturated linear fatty acids or fatty alcohols of 14 to 22 carbon atoms, saturated fatty acids of 14 to 22 carbon atoms, as saturated fatty or wax component. linear esters of waxes of 28 to 44 carbon atoms or mixtures thereof. Antitranspirant according to any one of claims 1 to 4, characterized in that it contains as an astringent salt aluminum hydroxide of the formula Αΐ2 (ΟΗ) 5 <31.2 to 3 H2O in an amount of 15 to 25% by weight. The antitranspirant composition of any one of claims 1 to 5, further comprising a finely divided filler of talc, silica, and mixtures thereof in an amount of 1 to 20% by weight.