WO2015085999A1

WO2015085999A1 - Antiperspirant cosmetic agents without compounds containing aluminum

Info

Publication number: WO2015085999A1
Application number: PCT/DE2014/200499
Authority: WO
Inventors: Bernhard Banowski; Melanie Giesen
Original assignee: Henkel Ag & Co. Kgaa
Priority date: 2013-12-11
Filing date: 2014-09-23
Publication date: 2015-06-18
Also published as: DE102013225617A1

Abstract

The invention relates to an antiperspirant cosmetic agent, containing a) at least one substance selected from the group of cosmetic oils that are liquid at 20 °C and 1.013 hPa, aromatic substances, and waxes, and b) bovine serum albumin (BSA), wherein the antiperspirant cosmetic agent does not contain any compounds containing aluminum. The addition of bovine serum albumin (BSA) ensures effective closure formation of the excretory ducts of the sweat gland(s) and thus results in an effective reduction of armpit sweat even in the absence of antiperspirant aluminum salts. Furthermore, the antiperspirant cosmetic agent without compounds containing aluminum is suitable in particular for sensitive skin.

Description

WELD-INHIBITING COSMETIC AGENTS WITHOUT ALUMINUM-CONTAINING COMPOUNDS

The present invention relates to an antiperspirant cosmetic composition without aluminum-containing compounds, which contains at least one substance selected from the group of cosmetic oils which are liquid at 20 ° C. and 1 .013 hPa, fragrances and waxes, and bovine serum albumin (BSA) and wherein the addition of bovine serum albumin (BSA) results in closure of the sweat gland (s).

Furthermore, the present invention relates to the use of a combination of at least one selected from the group of cosmetic oils which are liquid at 20 ° C and 1013 hPa, fragrances and waxes, and bovine serum albumin (BSA) for reducing and / or preventing Underarm perspiration or sweat of other body regions.

Moreover, the present invention relates to a non-therapeutic cosmetic method for preventing and / or reducing transpiration of the body, in which the antiperspirant according to the invention is applied to the skin, in particular to the skin of the armpits.

Finally, the present invention relates to the use of bovine serum albumin (BSA) for the at least partial closure of the sweat gland (s).

Washing, cleansing and caring for one's own body is a basic human need, and modern industry is constantly trying to meet these needs of man in a variety of ways. Especially important for daily hygiene is the permanent elimination or at least reduction of body odor and underarm wetness. Numerous specific deodorant or antiperspirant personal care products are known in the art which have been developed for use in body regions having a high density of sweat glands, especially in the underarm area. These are formulated in a wide variety of dosage forms, for example as powder, in stick form, as aerosol spray, pump spray, liquid and gel roll on application, cream, gel and as impregnated flexible substrates (towels).

Prior art cosmetic antiperspirants contain at least one antiperspirant salt in addition to at least one oil or fatty substance and one perfume component or perfume. The antiperspirant salts used in antiperspirants reduce sweat secretion of the body through a temporary narrowing and / or obstruction of the excretory ducts of the sweat glands, so that the amount of sweat can be reduced by about 20 to 60 percent. On the other hand, they have an additional deodorizing effect due to their antimicrobial effect.

As antiperspirant salts, usually activated basic aluminum and aluminum zirconium halides are used, as described in the publications EP 0 308 937 A2, EP 0 183 171 A2, US Pat. No. 4,359,456 A and EP 0 191 628. It is also possible to use aluminum and aluminum zirconium halides which are stabilized with organic acids as complexing ligands, as described, for example, in US Pat. Nos. 3,542,919, 3,553,316, 3,991,176 and WO 2005/092795 A1 are disclosed.

There is a need for antiperspirant cosmetic products which, on the one hand, reduce the risks of skin irritation in sensitive skin but, on the other hand, have a satisfactory antiperspirant effect. Furthermore, the antiperspirant cosmetic agents should be inexpensive to produce.

It is an object of the present invention to provide an antiperspirant cosmetic agent which avoids or at least attenuates the disadvantages of the prior art and which has a reduced skin irritation to sensitive skin, but at the same time reliably reduces underarm wetness.

It has now surprisingly been found that the use of bovine serum albumin (BSA) in cosmetic products without antiperspirant aluminum-containing compounds leads to gelation of these agents at pH values which prevail exclusively within the excretory ducts of the sweat glands, and thus an effective blockage of these Passageways guaranteed. Due to the selectivity of bovine serum albumin (BSA), gel formation does not take place either in the antiperspirant cosmetic products or on the outside of the skin so that the addition of bovine serum albumin (BSA) does not result in reduced antiperspirant efficacy due to premature gelation ,

The subject of the present invention is thus an antiperspirant cosmetic containing

(a) at least one substance selected from the group of cosmetic oils which are liquid at 20 ° C and 1 .013 hPa, fragrances and waxes, and

b) bovine serum albumin (BSA),

wherein the antiperspirant cosmetic agent contains no aluminum-containing compounds. By using bovine serum albumin (BSA) in the antiperspirant cosmetic agents according to the invention, gelation of bovine serum albumin (BSA) takes place, without wishing to be limited to this theory, only at extremely specific pH values. Due to the extremely selective formation of the gel at pH values, which are exclusively within the excretory ducts of the sweat glands, an effective blockage of the excretory ducts of the sweat glands is ensured, without the antiperspirant effect of the cosmetic product according to the invention by premature undesired gelation due to the addition of bovine serum albumin (BSA) is reduced. Thus, even in the absence of antiperspirant aluminum-containing compounds, effective reduction of armpit sweat is ensured. In the context of the present invention, it is also possible to use albumins which are obtained from animal sources, plants and human sources. In the context of the present invention, these albumins have a comparable effect as bovine serum albumin (BSA).

The term "antiperspirant" is understood according to the invention to reduce or reduce the perspiration of the sweat glands of the body.

In addition, in the context of the present invention, the term "aluminum-containing compounds" is understood to mean antiperspirant aluminum salts and aluminum-zirconium salts.

For the purposes of the present invention, the term "cosmetic oil" is understood to mean an oil which is suitable for cosmetic use and which is immiscible with water The cosmetic oil used according to the invention is neither fragrance nor essential oils.

In addition, the term "fragrances" in the context of the present invention means substances having a molecular weight of 74 to 300 g / mol, which contain at least one osmophoric group in the molecule and have an odor and / or taste, ie they are able to Osmophore groups are groups covalently bound to the molecular skeleton in the form of hydroxy groups, formyl groups, oxo groups, alkoxycarbonyl groups, nitrile groups, nitro groups, azide groups, etc. In this context, the term "fragrances" within the meaning of present invention even at 20 ° C and 1013 hPa liquid perfume oils, perfumes, or perfume oil ingredients.

In addition, the term "waxes" in the context of the present invention means substances which are kneadable at 20 ° C or solid to brittle hard, have a coarse to finely crystalline structure and color translucent to opaque, but not glassy. Furthermore, these substances melt above 25 ° C without decomposition, are slightly above the melting point slightly liquid (less viscous), have a strong temperature-dependent consistency and solubility and are polishable under light pressure.

The term "volatile cosmetic oil" according to the invention refers to cosmetic oils which at 20 ° C and an ambient pressure of 1 .013 hPa a vapor pressure of 2.66 Pa to 40,000 Pa (0.02 to 300 mm Hg), preferably from 10 to 12,000 Pa (0.1 to 90 mm Hg), more preferably from 13 to 3000 Pa (0.1 to 23 mm Hg), in particular from 15 to 500 Pa (0.1 to 4 mm Hg) have.

In addition, the term "nonvolatile cosmetic oils" in the context of the present invention means cosmetic oils which have a vapor pressure of less than 2.66 Pa (0.02 mm Hg) at 20 ° C. and an ambient pressure of 1.103 hPa ,

Furthermore, the term "fatty acid" as used in the present invention means aliphatic carboxylic acids which have unbranched or branched carbon residues of 4 to 40 carbon atoms also be synthetically produced fatty acids.Furthermore, the fatty acids may be monounsaturated or polyunsaturated.

Finally, the term "fatty alcohol" in the context of the present invention means aliphatic, monohydric, primary alcohols which have unbranched or branched hydrocarbon radicals having 4 to 40 carbon atoms The fatty alcohols used in the context of the invention may also be monounsaturated or polyunsaturated ,

The statement wt .-% refers in the present case, unless otherwise stated, on the total weight of the antiperspirant cosmetic agents according to the invention without any optional propellant.

According to a preferred embodiment of the present invention, the cosmetic oil which is liquid at 20 ° C and 1013 hPa is selected from the group of

(i) volatile cyclic silicone oils, especially cyclotrisiloxane, cyclotetrasiloxane, cyclopentasiloxane and cyclohexasiloxane, and linear silicone oils having 2 to 10 siloxane units, especially hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane;

(ii) volatile non-silicone oils, especially liquid paraffin oils and isoparaffin oils such as isodecane, isoundecane, isododecane, isotridecane, isotetradecane, isopentadecane, isohexadecane and isoeicosan;

(iii) nonvolatile silicone oils, especially higher molecular weight linear polyalkylsiloxanes;

(iv) non-volatile non-silicone oils, in particular the esters of linear or branched saturated or unsaturated C 2 to C 30 saturated or branched saturated or unsaturated fatty alcohols unsaturated C3-3 fatty acids which may be hydroxylated, the C8-C22 fatty alcohol esters of monohydric or polyvalent C2-C7 hydroxycarboxylic acids, the triethyl citrates, the branched saturated or unsaturated C6-3o fatty alcohols, the mono-, di- and triglycerides of linear or branched, saturated or unsaturated, optionally hydroxylated Cs-30 fatty acids, the dicarboxylic acid esters of linear or branched C 2 -C 10 -alkanols, the adducts of ethylene oxide and / or propylene oxide with mono- or polyhydric C 3-22 alkanols, which may be esterified may be the symmetrical, asymmetrical or cyclic esters of carbonic acid with fatty alcohols, the esters of dimers of unsaturated C 12-22 fatty acids with monovalent, linear, branched and cyclic C 2 -is-alkanols or C 2-6 -alkanols, the benzoic acid esters of linear or branched Cs-22-alkanols, such as benzoic acid Ci2-is-alkyl ester and benzoic acid isostearylester and Benzoic acid octyl dodecyl esters, the synthetic hydrocarbons such as polyisobutene and polydecenes, the alicyclic hydrocarbons; such as

(v) their mixtures.

The use of volatile silicone oils and volatile non-silicone oils in the antiperspirant cosmetic agents according to the invention results in a drier skin feel.

The cyclic volatile silicone oils which can be used in the context of the invention have a vapor pressure of from 13 to 15 Pa (0.1 mm Hg) at 20 ° C. and an ambient pressure of 1013 hPa. Furthermore, according to the invention as a linear volatile silicone oil and a low molecular weight phenyl trimethicone having a vapor pressure of about 2,000 Pa (15 mm Hg) at 20 ° C and an ambient pressure of 1013 hPa can be used. However, due to the high persistence of cyclodimethicones in the environment, it may be preferred according to the invention if 0 to less than 1 wt .-%, preferably 0 to less than 0.1 wt .-%, cyclic volatile silicone oils used in the antiperspirant cosmetic agents according to the invention become.

According to the invention, preference is given to volatile non-silicone oils in the form of Cio-13 isoparaffine mixtures having a vapor pressure of from 10 to 400 Pa (0.08 to 3 mm Hg), preferably from 13 to 100 Pa (0.1 to 0.8 mm Hg) , used at 20 ° C and an ambient pressure of 1 .013 hPa. It is preferred in the context of the present invention, if the volatile C8-Ci6-isoparaffin in a total amount of 1 to 60 wt .-%, preferably from 3 to 45 wt .-%, preferably from 5 to 40 wt .-%, in particular from 8 to 20 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included. Furthermore, it can also be provided in the context of the present invention that the volatile C8-C16 isoparaffin in a total amount of 1 to 80 wt .-%, preferably from 3 to 60 wt .-%, preferably from 5 to 50 wt. %, in particular from 8 to 20 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included. Of course it is also possible Antiperspirant cosmetic agents according to the invention with a low proportion of volatile oils - that is, with 0.5 to 15 wt .-%, based on the total weight of the antiperspirant cosmetic agent, on volatile oils - or even formulate without volatile oils.

In order to mask insoluble constituents, such as talc or skin-dried ingredients, it may be preferred according to the invention if the antiperspirant cosmetic agents contain a non-volatile silicone oil and / or a non-volatile non-silicone oil.

In this context, preferred antiperspirant cosmetic agents according to the invention contain at least one ester of linear or branched saturated or unsaturated fatty alcohols having 2 to 30 carbon atoms with linear or branched saturated or unsaturated fatty acids having 2 to 30 carbon atoms, which may be hydroxylated, in a total amount of 1 to 30 wt .-%, preferably from 5 to 26 wt .-%, preferably from 9 to 24 wt .-%, in particular from 12 to 17 wt .-%, based on the total weight of the antiperspirant cosmetic agent. However, it may also be preferred if the antiperspirant cosmetic agents of the present invention comprise at least one ester of linear or branched saturated or unsaturated fatty alcohols of 2 to 30 carbon atoms with linear or branched saturated or unsaturated fatty acids of 2 to 30 carbon atoms which may be hydroxylated Total amount of 1 to 80 wt .-%, preferably from 5 to 60 wt .-%, preferably from 9 to 40 wt .-%, in particular from 12 to 25 wt .-%, based on the total weight of the antiperspirant cosmetic agent ,

In the context of the present invention, non-volatile silicone oils may be linear polyalkylsiloxanes having a kinematic viscosity of from 5 to 2,000 cSt at 25 ° C., in particular linear polydimethylsiloxanes having a kinematic viscosity at 25 ° C. of from 5 to 2,000 cSt, preferably from 10 to 350 cSt, in particular from 50 to 100 cSt. The non-volatile silicone oils mentioned above are available under the tradenames Dow Corning ^® 200 or Xiameter PMX from Dow Corning or Xiameter. Further preferred nonvolatile silicone oils are phenyltrimethicones having a kinematic viscosity at 25 ° C. of from 10 to 100 cSt, preferably from 15 to 30 cSt, and also cetyldimethicones.

Further preferred according to the invention is the use of mixtures of the abovementioned cosmetic oils, in particular nonvolatile and volatile cosmetic oils, since in this way parameters such as skin feel, visibility of the residue and stability of the antiperspirant cosmetic agent according to the invention are adjusted and the agent is thus better suited to the needs of the invention Consumer can be adjusted. In the context of the present invention, it is preferred if the cosmetic oil which is liquid at 20 ° C. and 1 .013 hPa is present in a total amount of from 1 to 95% by weight, preferably from 10 to 85% by weight, preferably from 20 to 75 Wt .-%, more preferably from 35 to 70 wt .-%, in particular from 50 to 60 wt .-%, based on the total weight of the antiperspirant cosmetic agent contained.

However, it may also be preferred if the liquid cosmetic oil at 20 ° C and 1013 hPa in a total amount of 0.2 to 70 wt .-%, preferably from 2 to 60 wt .-%, preferably from 3 to 50 wt. -%, more preferably from 5 to 35 wt .-%, in particular from 8 to 20 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included. In this connection it can also be provided that the antiperspirant compositions according to the invention less than 0.2 wt .-%, preferably less than 0.1 wt .-%, in particular 0 wt .-% of at 20 ° C and 1 .013 hPa liquid cosmetic oil. The use of only extremely small amounts of the cosmetic oil which is liquid at 20 ° C. and 1 .013 hPa is particularly preferred in the case of antiperspirant cosmetic agents according to the invention which are present in aqueous, aqueous-alcoholic or aqueous-glycolic form.

According to a preferred embodiment of the present invention, the fragrance is selected from the group of

(i) esters, in particular benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, lactyl acetate, dimethylbenzylcarbinylacetate (DMBCA), phenylethylacetate, benzylacetate, ethylmethylphenylglycinate, allylcyclohexylpropionate, styrallylpropionate, benzylsalicylate, cyclohexylsalicylate, floramate, melusate and jasmecyclate;

(ii) ethers, especially benzyl ethyl ether and ambroxan;

(iii) aldehydes, especially linear alkanals of 8 to 18 carbon atoms, citral, citronellal, citronellyloxy-acetaldehyde, cyclamen aldehyde, lilial and bourgeonal;

(iv) ketones, especially ionone, alpha-isomethylionone and methyl cedryl ketone;

(v) alcohols, especially anethole, citronellol, eugenol, geraniol, linalool, phenylethyl alcohol and terpineol;

(vi) hydrocarbons, in particular terpenes such as limonene and pinene; such as

(vii) their mixtures.

However, mixtures of different fragrances are preferably used, which together produce an appealing scent.

Particularly pleasing antiperspirant cosmetic agents according to the invention are obtained when the perfume in a total amount of 0.00001 to 10 wt .-%, preferably from 0.001 to 9 wt .-%, preferably from 0.01 to 8 wt .-%, further preferably from 0.5 to 7 wt .-%, in particular from 1 to 6 wt .-%, based on the total weight of the antiperspirant cosmetic agent, is included. In this connection, however, it may also be provided that the fragrance in a total amount of 0.00001 to 5 wt .-%, preferably 0.001 to 4 wt .-%, preferably 0.01 to 3 wt .-%, more preferably 0 , 1 to 2 wt .-%, in particular 0.2 to 1, 5 wt .-%, based on the total weight of the blowing agent-containing antiperspirant cosmetic agent is included. However, it is also possible within the scope of the present invention that the perfume in a total amount of 0.00001 to 15 wt .-%, preferably 0.001 to 7 wt .-%, preferably 0.01 to 4 wt .-%, more preferably 0.1 to 2 wt .-%, in particular 0.2 to 1, 5 wt .-%, based on the total weight of the antiperspirant cosmetic agent is used.

According to another preferred embodiment of the present invention, the wax is selected from the group of

(i) fatty acid glycerol mono-, di- and triesters;

(ii) Butyrospermum Parkii (Shea Butter);

(iii) esters of saturated, monohydric Cs-is alcohols with saturated C12is monocarboxylic acids;

(iv) linear, primary C 12-24 alkanols;

(v) esters of a saturated monohydric C 16 -C 60 alkanol and a saturated C 8 -C 36 monocarboxylic acid, in particular cetyl behenate, stearyl behenate and C 20 -C 40 -alkyl stearate;

(vi) glycerol triesters of saturated linear C 12 -C 20 carboxylic acids which may be hydroxylated, in particular hydrogenated palm oil, hydrogenated coconut oil, hydrogenated castor oil, glyceryl tribehenate and glyceryl tri-12-hydroxy stearate;

(vii) natural vegetable waxes, especially candelilla wax, carnauba wax, Japan wax, sugarcane wax, ouricoury wax, cork wax, sunflower wax, fruit waxes;

(viii) animal waxes, in particular beeswax, shellac wax and spermaceti;

(ix) synthetic waxes, in particular montan ester waxes, hydrogenated jojoba waxes and sasol waxes, polyalkylene waxes and polyethylene glycol waxes, C 2o-C4o dialkyl esters of dimer acids, C 30-50 alkyl beeswax and alkyl and alkylaryl esters of dimer fatty acids, paraffin waxes; such as

(x) their mixtures.

Particular preference is given to commercial products having the INCI name Cocoglycerides, in particular the commercial products Novata® (ex BASF), particularly preferably Novata® AB, a mixture of C12-18 mono-, di- and triglycerides, which is in the range from 30 to 32 ° C melts, as well as the products of the Softisan series (Sasol Germany GmbH) with the INCI name Hydrogenated Cocoglycerides, in particular Softisan 100, 133, 134, 138, 142. Further preferred esters of saturated, monohydric Ci2-i8 alcohols with saturated Ci2 -i8 monocarboxylic acids are stearyl laurate, cetearyl stearate (eg Crodamol® CSS), cetyl palmitate (eg Cutina® CP) and myristyl myristate (eg Cetiol® MM). Furthermore, a C2o-C4o-alkyl stearate is preferably used as the wax component. This ester is known under the name Kester ^® K82H or Kesterwachs ^® K80H and Koster Keunen Inc. distributed.

In the context of the present invention, it is preferred if the wax in a total amount of 0.01 to 50 wt .-%, preferably from 3 to 40 wt .-%, preferably from 5 to 35 wt .-%, in particular from 6 to 25 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included.

In the present invention, a particularly effective reduction of axillary sweat is achieved by gelation of bovine serum albumin (BSA) when the bovine serum albumin (BSA) is present in a total amount of 0.05 to 15% by weight, preferably 0.1 to 10 wt .-%, preferably from 0.3 to 5 wt .-%, more preferably from 0.5 to 7 wt .-%, even more preferably from 0.8 to 5 wt .-%, in particular from 1 to 3 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included. However, it can also be provided within the scope of the invention that the antiperspirant cosmetic agents bovine serum albumin (BSA) in a total amount of 0.05 to 35 wt .-%, preferably 0.3 to 30 wt .-%, preferably 0, 5 to 25 wt .-%, more preferably from 0.7 to 15 wt .-%, even more preferably from 1, 0 to 12 wt .-%, in particular from 1, 5 to 10 wt .-%, based on the Total weight of the blowing agent-containing antiperspirant cosmetic agent included. Without wishing to be limited to this theory, the use of the abovementioned amount of bovine serum albumin (BSA) results in significantly increased and extremely pH-selective gel formation in the excretory ducts of the sweat glands. In this way, an effective blockage of the excretory ducts of the sweat glands and thus an excellent antiperspirant effect is ensured. Furthermore, the use of the aforementioned amount of bovine serum albumin (BSA) does not lead to undesirable premature gelation in the antiperspirant cosmetic or on the skin surface, so that the excellent antiperspirant effect is ensured even over long storage periods.

The antiperspirant cosmetic agent preferably contains free water in a total amount of less than 10% by weight, preferably less than 8% by weight, preferably less than 5% by weight, more preferably less than 3% by weight. even more preferably less than 1% by weight, in particular 0% by weight, based on the total weight of the antiperspirant cosmetic agent. For the purposes of the present invention, free water is thus understood to mean water which is different from water of crystallization, water of hydration or similar molecularly bound water of the constituents used.

Surprisingly, it has been found that clogging of the excretory ducts of the sweat glands can be significantly increased due to the gelation of bovine serum albumin (BSA) when the antiperspirant cosmetic agents according to the invention have free water in them an amount of from 15 to 99% by weight, based on the total weight of the antiperspirant cosmetic agent. In a particularly preferred embodiment of the present invention, the antiperspirant cosmetic agent therefore contains free water in a total amount of 15 to 96 wt .-%, preferably from 25 to 80 wt .-%, preferably from 30 to 70 wt .-%, in particular of 40 to 60 wt .-%, based on the total weight of the antiperspirant cosmetic agent. However, it can also be provided that the antiperspirant cosmetic agent according to the invention comprises free water in a total amount of from 15 to 99% by weight, preferably from 25 to 90% by weight, preferably from 30 to 80% by weight, in particular from 40 to 60 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains.

In a further preferred dosage form, the antiperspirant cosmetic agent is present as a water-in-oil emulsion. This may in particular be a sprayable water-in-oil emulsion, which can be sprayed by means of a propellant. In this connection, it is preferred if the antiperspirant cosmetic agent according to the invention present in the form of a water-in-oil emulsion comprises bovine serum albumin (BSA) in a total amount of from 0.05 to 20% by weight, preferably from 0.1 to 15% by weight, preferably from 0.3 to 10% by weight, more preferably from 0.5 to 7% by weight, still more preferably from 0.8 to 5% by weight, most preferably from 1 to 3 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains. However, it may also be provided in this context that the antiperspirant cosmetic agent according to the invention lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 25 wt .-%, preferably from 0.3 to 18 Wt .-%, more preferably from 0.5 to 15 wt .-%, in particular from 1 to 12 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains.

In the context of the present invention, it can also be provided that the antiperspirant cosmetic agent is present as an oil-in-water emulsion. In this case, the agent according to the invention is preferably sprayed as a propellant-free pump spray or squish spray or applied as a roll-on. In this connection, it is preferred that the antiperspirant cosmetic agent present in the form of an oil-in-water emulsion contains bovine serum albumin (BSA) in a total amount of from 0.05 to 20% by weight, preferably from 0.1 to 15% Wt .-%, preferably from 0.3 to 10 wt .-%, more preferably from 0.5 to 7 wt .-%, even more preferably from 0.8 to 5 wt .-%, in particular from 1 to 3 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains. However, it may also be provided in this connection that the antiperspirant cosmetic agent according to the invention comprises lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 25 wt .-%, preferably from 0.3 to 18 wt .-%, more preferably from 0.5 to 15 wt .-%, in particular from 1 to 12% by weight, based on the total weight of the antiperspirant cosmetic agent.

According to the invention, it may further be provided that the antiperspirant cosmetic agent is present as an aqueous, aqueous-alcoholic or aqueous-glycolic solution. Since the cosmetic compositions according to the invention contain no ingredients such as, for example, antiperspirant aluminum-containing compounds which have a reduced antiperspirant effect by the addition of protic solvents, protic solvents, such as aqueous solutions, can be used according to the invention for formulating the antiperspirant cosmetic compositions according to the invention, without a significant reduction the antiperspirant effect occurs. Therefore, the addition of bovine serum albumin (BSA), even with the use of protic solvents, ensures effective closure of the excretory ducts of the sweat gland and thus excellent antiperspirant activity.

According to a preferred embodiment of the present invention, the antiperspirant cosmetic agent contains ethanol in a total amount of 1 to 99 wt .-%, preferably from 5 to 70 wt .-%, preferably from 7 to 50 wt .-%, in particular from 10 to 30 Wt .-%, based on the total weight of the antiperspirant cosmetic agent. However, it can also be provided that the antiperspirant cosmetic agent ethanol in a total amount of 10 to 95 wt .-%, preferably from 15 to 90 wt .-%, preferably from 20 to 87 wt .-%, more preferably from 30 to 85 wt .-%, in particular from 40 to 80 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains. As stated above, even high levels of protic solvents, such as ethanol, can be used by the use of bovine serum albumin (BSA) without negatively affecting the antiperspirant activity of the antiperspirant cosmetic agent of the present invention.

In the context of the present invention, it is preferred if the pH of the antiperspirant cosmetic agent according to the invention in at least one of the ranges from pH 2.0 to pH 6.0 or pH 7.0 to pH 11, 0, preferably pH 2.5 to pH 5.5 or pH 7.5 to pH 10.0, preferably pH 3.0 to pH 5.0 or pH 8.0 to pH 9.5. The adjustment of the desired pH can be carried out according to the invention by using customary in antiperspirant cosmetic agents acids and bases.

The application of the antiperspirant cosmetic agent according to the invention can be carried out by means of various methods. According to a preferred embodiment, the antiperspirant cosmetic agent is formulated as a spray application. The spray application is carried out with a spray device, which in a container, a filling of the invention liquid, viscous-flowable, suspension-shaped or powdered antiperspirant cosmetic agents. The filling may be under the pressure of a propellant (compressed gas cans, compressed gas packages, aerosol dispensers), or it may be a mechanically operated pump sprayer without propellant (pump sprays / squeeze bottle). The containers have a removal device, preferably in the form of valves, which allow the removal of the contents as a mist, smoke, foam, powder, paste or liquid jet. Cylindrical vessels made of metal (aluminum, tinplate, volume preferably not more than 1 .000 ml), protected or non-splintering glass or plastic (preferably a maximum of 220 ml) or splintering glass or plastic (volume preferably 50) are used as containers for the spraying devices to 400 ml) in question. Creamy, gelatinous, pasty and liquid agents may be packaged, for example, in pump, spray or squeeze dispensers, in particular in multi-chamber pumping, multi-chamber spray or multi-chamber squeeze dispensers. The packaging for the compositions according to the invention may be opaque, but also transparent or translucent.

The antiperspirant cosmetic is preferably formulated as a stick, soft solid, cream, roll-on, dibenzylidenalditol-based gel, loose or compact powder. The formulation of the antiperspirant cosmetic agents according to the invention in a particular dosage form, such as, for example, an antiperspirant roll-on, an antiperspirant stick or an antiperspirant gel, preferably conforms to the requirements of the intended use. Depending on the intended use, the antiperspirant cosmetic agents according to the invention can therefore be present in solid, semisolid, liquid, disperse, emulsified, suspended, gelatinous, multiphase or powdery form. For the purposes of the present invention, the term liquid also includes any types of solid dispersions in liquids. In the context of the present invention, multiphase antiperspirant cosmetic agents according to the invention are also understood to mean agents which have at least two different phases with a phase separation and in which the phases can be arranged horizontally, ie one above the other, or vertically, ie side by side.

The application can be done, for example, with a roller ball applicator. Such rollers have a ball mounted in a ball bed, which can be moved by movement over a surface. In this case, the ball absorbs some of the antiperspirant cosmetic agent according to the invention to be distributed and conveys it to the surface to be treated. The packaging for the compositions according to the invention can, as stated above, be opaque, transparent or translucent.

Furthermore, it is also possible to apply the antiperspirant cosmetic agents according to the invention by means of a solid stick. However, it may also be preferred according to the invention that the antiperspirant cosmetic agent is contained on and / or in a disposable substrate selected from the group of wipes, pads and bulbs. Particularly preferred are wet wipes, ie prefabricated for the user, preferably individually packaged, wet wipes, as they are for. B. from the field of glass cleaning or from the field of wet toilet paper are well known. Such wet wipes, which can advantageously also contain preservatives, are impregnated or applied with an antiperspirant cosmetic agent according to the invention and preferably individually packaged. You can z. B. be used as a deodorant cloth, which is particularly interesting for use on the go. Preferred substrate materials are selected from porous sheet-like cloths. They can be made of a fibrous or cellular flexible material which has sufficient mechanical stability and softness for application to the skin. These wipes include wipes of woven and nonwoven synthetic and natural fibers, felt, paper or foam, such as hydrophilic polyurethane foam. Deodorizing or antiperspirant substrates which are preferred according to the invention can be obtained by impregnation or impregnation or else by melting a perspiration-inhibiting cosmetic agent according to the invention onto a substrate.

The antiperspirant cosmetic agents of the present invention may further contain other adjuvants. The antiperspirant cosmetic agents according to the invention preferably contain at least one wide adjuvant selected from the group of (i) emulsifiers and / or surfactants; (ii) thickeners; (iii) chelating agents; (iv) deodorant agents; (v) monohydric and / or polyhydric alcohols and / or polyethylene glycols; (vi) skin-cooling agents; (vii) propellants; (viii) preservatives; (ix) pH adjusters and (x) mixtures thereof.

Emulsifiers and surfactants which are preferably suitable according to the invention are selected from anionic, cationic, nonionic, amphoteric, in particular ampholytic and zwitterionic emulsifiers and surfactants. Surfactants are amphiphilic (bifunctional) compounds which consist of at least one hydrophobic and at least one hydrophilic moiety. The hydrophobic moiety is preferably a hydrocarbon chain of 8 to 28 carbon atoms, which may be saturated or unsaturated, linear or branched. Most preferably, this C8-C28 alkyl chain is linear.

By anionic surfactants are meant surfactants with exclusively anionic charges; they contain z. As carboxyl groups, sulfonic acid groups or sulfate groups. Particularly preferred anionic surfactants are alkyl sulfates, alkyl ether sulfates, acyl glutamates and Cs-24-carboxylic acids and their salts, the so-called soaps. Cationic surfactants are understood as meaning surfactants with exclusively cationic charges; they contain z. B. quaternary ammonium groups. Preference is given to cationic surfactants of the quaternary ammonium compounds, esterquats and amidoamines type. Preferred quaternary ammonium compounds are ammonium halides and the imidazolium compounds known under the INCI names Quaternium-27 and Quaternium-83. Further cationic surfactants which can be used according to the invention are the quaternized protein hydrolysates. Preferred esterquats are quaternized ester salts of fatty acids with triethanolamine, quaternized ester salts of fatty acids with diethanolalkylamines and quaternized ester salts of fatty acids with 1,2-dihydroxypropyldialkylamines.

The amphoteric surfactants are subdivided into ampholytic surfactants and zwitterionic surfactants. Ampholytic surfactants are understood as meaning those surface-active compounds which have both acidic (for example -COOH or -SCbH groups) and basic hydrophilic groups (for example amino groups) and thus behave acidic or basic depending on the condition. Zwitterionic surfactants are understood by the person skilled in the art to be surfactants which carry both a negative and a positive charge in the same molecule. Examples of preferred zwitterionic surfactants are the betaines, the N-alkyl-N, N-dimethylammonium glycinates, the N-acyl-aminopropyl-N, N-dimethylammoniumglycinate and the 2-alkyl-3-carboxymethyl-3-hydroxyethyl-imidazoline with each 8 to 24 carbon atoms in the alkyl group. Examples of preferred ampholytic surfactants are N-alkylglycines, N-alkylaminopropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids each having 8 to 24 carbon atoms in the alkyl group

The compositions of the invention, which are formulated as an emulsion, in particular as an oil-in-water emulsion, preferably contain at least one nonionic oil-in-water emulsifier having an HLB value of more than 7 to 20. This is themselves to those skilled in the well-known emulsifiers, as, for example, in Kirk-Othmer, "Encyclopedia of Chemical Technology", 3rd ed., 1979, Volume 8, page 913-916 listed. For ethoxylated products, the HLB value is calculated according to the formula HLB = (100-L): 5, where L is the weight fraction of the lipophilic groups, that is the fatty alkyl or fatty acyl groups, in the ethylene oxide adducts, expressed in weight percent. In this context, it may be preferred according to the invention if, furthermore, a water-in-oil emulsifier having an HLB value of greater than 1.0 and less than or equal to 7.0 is used. Nonionic oil-in-water emulsifiers suitable for the purposes of the present invention and suitable nonionic water-in-oil emulsifiers are described, for example, in German Offenlegungsschrift DE 10 2006 004 957 A1.

For thickening the antiperspirant cosmetic agents according to the invention it is preferred to use substances which are selected from cellulose ethers, in particular hydroxyalkylcelluloses, in particular hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose, carboxymethylcellulose, cetylhydroxyethylcellulose, hydroxybutylmethylcellulose, methylhydroxyethylcellulose, furthermore xanthan gum, sclerotium gum, succinoglucans, polygalactomannans, in particular guar gum and locust bean gum, in particular guar gum and locust bean gum itself and the nonionic hydroxyalkyl guar derivatives and locust bean gum derivatives such as hydroxypropylguar, carboxymethylhydroxypropylguar, hydroxypropylmethylguar, hydroxyethylguar and carboxymethylguar, pectins, agar, carrageenan, tragacanth, gum arabic, karaya gum, tara gum, gellan, gelatin, casein, propylene glycol alginate, alginic acids and their salts, in particular sodium alginate, potassium alginate and calcium alginate, furthermore polyvinylpyrrolidones, polyvinyl alcohols, polyacrylamides, furthermore - although less preferably - physically (for example by pre-gluing) g) and / or chemically modified starches, in particular hydroxypropylated starch phosphates and octenyl starch succinates and their aluminum, calcium or sodium salts, furthermore - also less preferred - acrylic acid-acrylate copolymers, acrylic acid-acrylamide copolymers, acrylic acid-vinylpyrrolidone copolymers, acrylic acid Vinylformamide copolymers and polyacrylates. Particularly preferred thickeners are selected from cellulose ethers, especially from hydroxyalkylcelluloses, in particular from hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose, carboxymethylcellulose, cetylhydroxyethylcellulose, hydroxybutylmethylcellulose and methylhydroxyethylcellulose, and mixtures thereof. Particularly preferred thickeners are furthermore selected from carbomers. Carbomers are thickening crosslinked polymers of acrylic acid, methacrylic acid and their salts. The crosslinking can be effected by means of polyfunctional compounds such as polyalkylene ethers of polysaccharides or polyalcohols, for example sucrose allyl ether, pentaerythritol allyl ether, propylene allyl ether. Preferred in the context of the present invention are homopolymers of acrylic acid or salts thereof which are crosslinked with a pentaerythritol allyl ether, a sucroseallyl ether or a propylene allyl ether. A thickening agent which can be used in the context of the present invention is a copolymer of Cio-30-alkyl acrylate, acrylic acid, methacrylic acid and esters thereof, which is crosslinked with a sucrose allyl ether or a pentaerythritol allyl ether. Thickener based on carbomers are products sold under the trade name Carbopol ^® (BF Goodrich, Ohio, USA) available such as Carbopol 934, Carbopol 940, Carbopol 941, Carbopol 971, Carbopol 974, Carbopol EZ2, Carbopol ETD 2001, Carbopol ETD 2020, Carbopol ETD 2050, Carbopol uitrez 10, Carbopol ultrez 20, or Carbopol uitrez 2.

In order to further support the blockage of the excretory ducts of the sweat glands by the gel formation with the addition of bovine serum albumin (BSA), it may be advantageous for the antiperspirant cosmetic agents according to the invention to contain at least one chelating agent selected from ethylenediaminetetraacetic acid (EDTA) and its salts as well as out Nitrilotriacetic acid (NTA) and mixtures of these substances, in a total amount of 0.01 to 0.5 wt .-%, preferably from 0.02 to 0.3 wt .-%, in particular from 0.05 to 0.1 wt. -%, based on the total weight of the antiperspirant agent according to the invention, to add. However, chelating agents which are selected from the group of β-alaninediacetic acid, cyclodextrin, can also be used in the context of the present invention.

Diethylenetriaminepentamethylenephosphonic acid, sodium, potassium, calcium disodium, ammonium and triethanolamine salts of ethylenediaminetetraacetic acid (EDTA), etidronic acid, hydroxyethylethylenediaminetetraacetic acid (HEDTA) and their sodium salts, sodium nitriles of nitrilotriacetic acid (NTA), diethylenetriaminepentaacetic acid, phytic acid, hydroxypropylcyclodextrin, methylcyclodextrin, aminotrimethylenephosphonate-pentasodium, Ethylenediamine tetramethylenephosphonate pentasodium, diethylenetriaminepentaacetate-pentasodium, pentasodium triphosphate, potassium EDTMP, sodium EDTMP, sodium dihydroxyethylglycinate, sodium phytate, sodium polydimethylglycinophenolsulphonate, tetrahydroxyethylethylenediamine, tetrahydroxypropylethylenediamine, tetrapotassium tetidronate, tetrasodiumetidronate,

Tetrasodiumiminodisuccinate, trisodium ethylenediamine disuccinate and desferrioxamine.

The antiperspirant effect of the antiperspirant cosmetic agents according to the invention can be further increased if at least one deodorant active ingredient with anti-bacterial and / or bacteriostatic and / or enzyme-inhibiting and / or odor-neutralizing and / or odor-absorbing effect in a total amount of 0.0001 to 40% by weight. %, preferably from 0.2 to 20 wt .-%, preferably from 1 to 15 wt .-%, in particular from 1, 5 to 5 wt .-%, based on the total weight of the antiperspirant cosmetic agent according to the invention, is contained. If ethanol is used in the compositions according to the invention, this does not apply in the context of the present invention as a deodorant active ingredient, but as a constituent of the carrier. Deodorant agents which are preferred according to the invention are selected from the group of (i) silver salts; (ii) aromatic alcohols, in particular 2-benzylheptan-1-ol and mixtures of 2-benzylheptan-1-ol and phenoxyethanol; (iii) 1,2-alkanediols having 5 to 12 carbon atoms, especially 3- (2-ethylhexyloxy) -1,2-propanediol; (iv) triethyl citrate; (v) agents against exoesterases, especially against arylsulfatase, lipase, beta-glucuronidase and cystathion-beta-lyase; (vi) cationic phospholipids; (vii) odor absorbers, especially silicates such as montmorillonite, kaolinite, hit, beidellite, nontronite, saponite, hectorite, bentonite, smectite and talc, zeolites, zinc ricinoleate, cyclodextrins; (viii) deodorizing ion exchanger; (ix) antimicrobial agents; (x) prebiotic active components; and (xi) mixtures of these deodorant agents.

Preferred antiperspirant cosmetic agents according to the invention also contain at least one water-soluble polyhydric C 2-9 -alkanol having 2 to 6 hydroxyl groups and / or at least one water-soluble polyethylene glycol having 3 to 50 ethylene oxide units and mixtures hereof. This does not include the abovementioned deodorant active ingredients in the form of 1, 2-alkanediols. Preferred alkanols are selected from 1, 2-propylene glycol, 2-methyl-1, 3-propanediol, glycerol, 1, 2-butylene glycol, 1, 3-butylene glycol, 1, 4-butylene glycol, pentylene glycols such as 1, 2-pentanediol and 1, 5-pentanediol, hexanediols such as 1, 2-hexanediol and 1, 6-hexanediol, hexanetriols such as 1, 2,6-hexanetriol, 1, 2-octanediol, 1, 8-octanediol, dipropylene glycol, tripropylene glycol, diglycerol, triglycerol , Erythritol, sorbitol, cis-1,4-dimethylolcyclohexane, trans-1,4-dimethylolcyclohexane, any mixtures of isomers of cis- and trans-1,4-dimethylolcyclohexane, as well as mixtures of the abovementioned substances. Suitable water-soluble polyethylene glycols are selected from PEG-3, PEG-4, PEG-6, PEG-7, PEG-8, PEG-9, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18 and PEG-20 and mixtures thereof, with PEG-3 to PEG-8 being preferred.

According to another embodiment of the present invention, the antiperspirant cosmetic agents further contain at least one skin-cooling agent. Skin-cooling active ingredients suitable according to the invention are, for example, menthol, isopulegol and menthol derivatives, eg. Eg menthyl lactate, menthyl glycolate, menthyl ethyl oxamate, menthyl pyrrolidone carboxylic acid, menthyl methyl ether, menthoxy propane diol, menthone glycerol acetal (9-methyl-6- (1-methylethyl) -1, 4-dioxaspiro (4.5) decane-2-methanol), monomethyl succinate, 2 -Hydroxymethyl-3,5,5-trimethylcyclohexanol and 5-methyl-2- (1-methylethyl) cyclohexyl-N-ethyloxamate. Preferred skin-cooling active ingredients are menthol, isopulegol, menthyl lactate, menthoxypropanediol, menthylpyrrolidonecarboxylic acid and 5-methyl-2- (1-methylethyl) cyclohexyl-N-ethyloxamate, as well as mixtures of these substances, in particular mixtures of menthol and menthyl lactate, menthol, menthol glycolate and menthyl lactate, menthol and menthoxypropanediol or menthol and isopulegol.

Furthermore, it can be provided that the antiperspirant cosmetic agents according to the invention contain a propellant. In this case, they are formulated as a propellant-driven aerosol. Preferred propellants (propellants) are propane, propene, n-butane, isobutane, isobutene, n-pentane, pentene, isopentane, isopentene, methane, ethane, dimethyl ether, nitrogen, air, oxygen, nitrous oxide, 1, 1, 1, 3-tetrafluoroethane, heptafluoro-n-propane, perfluoroethane, monochlorodifluoromethane, 1, 1 - difluoroethane, tetrafluoropropenes, both individually and in their mixtures. Also hydrophilic propellants, such. As carbon dioxide, can be used advantageously in the context of the present invention, when the proportion of hydrophilic gases is selected low and lipophilic propellant gas (eg., Propane / butane) is present in excess. Particularly preferred are propane, n-butane, isobutane and mixtures of these propellants. It has been found that the use of n-butane as the only propellant gas according to the invention can be particularly preferred. The total amount of the blowing agent is 20 to 95 wt.%, Preferably 30 to 85 wt.%, In particular 40 to 75 wt .-%, each based on the total weight of the antiperspirant, consisting of the inventive antiperspirant cosmetic agent, the blowing agent and optionally further excipients. In In this connection it can also be provided that the total amount of blowing agent 1 to 95 wt .-%, preferably 2 to 85 wt .-%, in particular 3 to 75 wt .-%, .-%, each based on the total weight of the antiperspirant consisting of the antiperspirant cosmetic agent according to the invention and the propellant.

As excipients, lipophilic thickeners can furthermore be used according to the invention. The bovine serum albumin (BSA) is preferably suspended undissolved in at least one cosmetic oil which is liquid at 20 ° C. and 1 .013 hPa. For better usability, at least one lipophilic thickener may be added to this suspension as a suspending aid. Lipophilic thickeners preferred according to the invention are selected from hydrophobized clay minerals and fumed silicic acids.

The antiperspirant cosmetic agents of the present invention may further contain at least one preservative. Preservatives preferred according to the invention are formaldehyde releasers (such as, for example, 1,3-dimethylol-4,4-dimethylhydantoin, INCI name DMDM hydantoin, available, for example, under the trade name Glydant from Lonza), iodopropynyl butyl carbamates, such as 3-iodo-2-propynyl butyl carbamate (e.g., those available under the trade designations Glycacil-L, Glycacil-S from Lonza, and / or Dekaben LMB from Jan Dekker), parabens (ie, p-hydroxybenzoic acid alkyl esters, such as methyl, ethyl , Propyl and / or butylparaben), phenoxyethanol, ethanol, benzoic acid, dibromodicyanobutane (2-bromo-2-bromomethylglutarodinitrile), 2-bromo-2-nitro-propane-1,3-diol, imidazolidinylurea, 5-chloro-2 -methyl-4-isothiazolin-3-one, 2-chloroacetamide, benzalkonium chloride, benzyl alcohol, salicylic acid and salicylates. Further preservatives which can be used in the context of the present invention are the substances listed in Annex 6 of the Cosmetics Regulation. The preservatives are preferably in a total amount of 0.01 to 10 wt .-%, preferably from 0.1 to 7 wt .-%, preferably from 0.2 to 5 wt .-%, in particular from 0.3 to 2, 0 wt .-%, based on the total weight of the antiperspirant cosmetic agent included.

According to the invention, the pH adjusting agents used are preferably acids and / or alkalizing agents and / or buffers.

As acids according to the invention preferably mineral acids (such as hydrochloric acid, sulfuric acid or phosphoric acid) or edible acids (such as citric acid, tartaric acid or malic acid) are used.

The alkalizing agents which can be used according to the invention and are preferably selected from the group formed from ammonia, basic amino acids, alkali hydroxides, alkanolamines, alkali metal metasilicates, urea, morpholine, N-methylglucamine, imidazole, alkali phosphates and Alkali metal hydrogen phosphates. The alkali metal ions used are preferably lithium, sodium, potassium, in particular sodium or potassium. The basic amino acids which can be used as alkalizing agents according to the invention are preferably selected from the group formed from L-arginine, D-arginine, D, L-arginine, L-histidine, D-histidine, D, L-histidine, L-lysine, D-lysine, D, L-lysine, more preferably L-arginine, D-arginine, D, L-arginine used as an alkalizing agent according to the invention. The alkali metal hydroxides which can be used as the alkalizing agent according to the invention are preferably selected from the group formed from sodium hydroxide and potassium hydroxide. The alkanolamines which can be used as alkalizing agents according to the invention are preferably selected from primary amines having a C 2 -C 6 -alkyl basic body which carries at least one hydroxyl group. Particularly preferred alkanolamines are selected from the group formed from 2-aminoethane-1-ol (monoethanolamine), 3-aminopropan-1-ol, 4-aminobutan-1-ol, 5-aminopentan-1-ol, 1 - aminopropan-2-ol, 1-aminobutan-2-ol, 1-aminopentan-2-ol, 1-aminopentan-3-ol, 1-aminopentan-4-ol, 3-amino-2-methylpropan-1-ol , 1-amino-2-methylpropan-2-ol, 3-aminopropane-1, 2-diol, 2-amino-2-methylpropane-1,3-diol.

Suitable buffer systems in the context of the present invention are, in particular, carbonic acid bicarbonate buffers, carbonic acid silicate buffers, acetic acid acetate buffers, phosphate buffers, ammonia buffers, citric acid or citrate buffers, buffers based on tris (hydroxymethyl) aminomethane, buffers Base of 4- (2-hydroxyethyl) -1-piperazineethanesulfonic acid, buffer based on 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, buffer based on 2- (N-morpholino) ethanesulfonic acid and barbital acetate buffer , The choice of the corresponding buffer system depends on the desired pH of the antiperspirant cosmetic composition according to the invention.

In a preferred embodiment, the antiperspirant cosmetic agents according to the invention are characterized in that they are formulated as a water-in-oil emulsion and, based on the total weight of the antiperspirant cosmetic agent according to the invention,

Bovine serum albumin (BSA) in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7

Wt .-%, even more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%,

From 12 to 90% by weight, preferably from 25 to 55% by weight, preferably from 30 to 50% by weight, in particular from 35 to 45% by weight, of water,

at least one emulsifier and

at least one substance selected from the group of cosmetic oils which are liquid at 20 ° C and 1 .013 hPa, fragrances and waxes

contain. In the context of this embodiment, however, it may also be provided that the Bovine serum albumin (BSA) in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, still more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-% and water in a total amount of 12 to 99 wt .-%, each based on the total weight of the antiperspirant cosmetic agent , is included.

In a further preferred embodiment, the antiperspirant cosmetic agents according to the invention are characterized in that they are formulated as an oil-in-water emulsion and, based on the total weight of the antiperspirant cosmetic agent according to the invention,

Wt .-%, even more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%,

From 15 to 90% by weight, preferably from 25 to 55% by weight, preferably from 30 to 50% by weight, in particular from 35 to 45% by weight, of water,

at least one emulsifier and

contain. In the context of this embodiment, however, it may also be provided that the bovine serum albumin (BSA) in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-% and water in a total amount of 12 to 98 wt .-%, in each case based on the total weight of the antiperspirant cosmetic agent is included.

A further preferred embodiment of the present invention comprises antiperspirant cosmetic agents according to the invention, which are characterized in that they contain, based on the total weight of the antiperspirant cosmetic agent according to the invention,

Bovine serum albumin (BSA) in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 Wt .-%, even more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%,

15 to 90 wt .-%, preferably 25 to 80 wt .-%, preferably 30 to 75 wt .-%, in particular 40 to 60 wt .-% water, and

0.01 to 2 wt .-%, preferably 0.1 to 1 wt .-%, preferably 0.2 to 0.7 wt .-%, in particular 0.3 to 0.5 wt .-% of a thickener

contain. In the context of this embodiment, however, it may also be provided that the bovine serum albumin (BSA) in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15% by weight, preferably 0.3 to 10% by weight, more preferably 0.5 to 7% by weight, even more preferably 0.8 to 5% by weight, especially 1 to 3 wt .-%, water in a total amount of 12 to 98 wt .-% and thickening agent in a total amount of 0.01 to 5 wt .-%, each based on the total weight of the antiperspirant cosmetic agent is included.

wherein the antiperspirant cosmetic agents according to the invention have a dynamic viscosity in the range from 10 to 5000 mPas, preferably from 100 to 1000 mPas, preferably from 200 to 800 mPas, measured with a Brookfield viscometer, spindle RV 4, 20 s, without Helipath at 20 ° C ambient temperature and 20 ° C sample temperature. In the context of this embodiment, however, it may also be provided that the bovine serum albumin (BSA) in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, still more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%, water in a total amount of 12 to 98 wt .-% and thickening agent in a total amount of 0.01 to 5 wt .-%, each based on the total weight of the antiperspirant cosmetic agent is included.

Bovine serum albumin (BSA) in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%,

15 to 98 wt .-%, preferably 25 to 80 wt .-%, preferably 30 to 75 wt .-%, in particular 40 to 60 wt .-% water, and

0.01 to 5 wt .-%, preferably 0.1 to 1 wt .-%, preferably 0.2 to 0.7 wt .-%, in particular 0.3 to 0.5 wt .-% of a thickener

contain, wherein the antiperspirant cosmetic agents according to the invention a dynamic Viscosity in the range of 1 .000 to 800,000 mPas, preferably from 2,000 to 700,000 mPas, preferably from 3,000 to 500,000 mPas, measured with a Brookfield viscometer, spindle RV 4, 20 s ^"1 , without Helipath, at 20 ° C ambient temperature and 20 ° C sample temperature.

In another preferred embodiment, the antiperspirant cosmetic agents according to the invention are characterized in that they are formulated as a water-in-oil emulsion and, based on the total weight of the antiperspirant cosmetic agent according to the invention,

15 to 75 wt .-%, preferably 25 to 60 wt .-%, preferably 30 to 55 wt .-%, in particular 35 to 50 wt .-% water

optionally 0.01 to 2 wt .-%, preferably 0.1 to 1 wt .-%, preferably 0.2 to 0.7

Wt .-%, in particular 0.3 to 0.5 wt .-% of a thickener

contain. In the context of this embodiment, however, it may also be provided that the bovine serum albumin (BSA) in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, still more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%, water in a total amount of 12 to 98 wt .-% and thickening agent in a total amount of 0.01 to 5 wt .-%, each based on the total weight of the antiperspirant cosmetic agent is included. In the context of the present invention, it may also be envisaged to prepare the cosmetic agent according to the invention as a two-component agent. For this purpose, the individual components are preferably stored in separate containers and applied in succession to the skin in any order. Cosmetic compositions according to the invention can therefore, as kit-of-parts, containing, separated from one another, a) at least one first container containing a cosmetic agent comprising at least one antiperspirant aluminum-containing compound, and

b) at least one second container containing a cosmetic agent comprising bovine serum albumin (BSA), wherein the cosmetic agent contains no aluminum-containing compounds,

available.

In the context of the present invention, the term "aluminum-containing compounds" is understood to mean antiperspirant aluminum salts and aluminum-zirconium salts.

A second object of the present invention is the use of a combination of at least one selected from the group of cosmetic oils which are liquid at 20 ° C and 1013 hPa, fragrances and waxes, and bovine serum albumin (BSA) for reducing and / or Prevention of sweat. The term "combination" within the meaning of the present invention also encompasses a mixture of the at least one substance with bovine serum albumin (BSA) With regard to the use of the abovementioned combination, what has been said with respect to the antiperspirant cosmetic agents according to the invention applies mutatis mutandis.

Furthermore, a third aspect of the present invention is a non-therapeutic cosmetic method for preventing and / or reducing transpiration of the body, which comprises an antiperspirant cosmetic agent containing at least one selected from the group of cosmetic oils at 20 ° C and 1.013 hPa liquid, fragrances and waxes, and bovine serum albumin (BSA), is applied to the skin, especially to the skin of the underarms.

In the context of the method according to the invention, however, it may also be provided that initially a cosmetic agent containing an antiperspirant aluminum salt and then the cosmetic composition according to the invention containing bovine serum albumin (BSA) is applied. However, it is also possible first to apply the cosmetic agent according to the invention containing bovine serum albumin (BSA) and then to use a cosmetic agent containing an antiperspirant aluminum salt. The time between application of the two remedies is from 10 seconds to 24 hours. With regard to the method according to the invention Mutatis mutandis applies mutatis mutandis to the antiperspirant cosmetic agents according to the invention and to the use according to the invention.

Finally, a fourth subject of the present invention is the use of bovine serum albumin (BSA) to at least partially occlude the sweat gland (s).

Closure formation of the sweat gland (s) according to the invention means the formation of a gel and / or precipitate of bovine serum albumin (BSA) in the excretory duct of the sweat gland or the excretory ducts of the sweat glands. This occlusion avoids or reduces secretion of sweat from the duct. With regard to the use according to the invention of bovine serum albumin (BSA), the statements made on the cosmetic antiperspirant compositions according to the invention apply mutatis mutandis.

The following examples illustrate the present invention without, however, limiting it to:

Examples:

Antiperspirant cosmetic agents according to the invention (amounts in% by weight)

Cosmetic compositions in the form of an oil-in-water emulsion (amounts in% by weight)

7 8 9

Cutina® AGS 2.5 2.5 2.5 Cutina® FS45 3,5 3,5 3,5

Eumulgin ^® B2 0.8 0.8 0.8

Eumulgin ^® B3 0.8 0.8 0.8

Diisopropyladipate 6.0 6.0 6.0

Novata ^® AB 4.0 4.0 4.0

Cutina CP ^® 5.0 5.0 5.0

Cutina ^® HR 4.0 4.0 4.0

Kester wax K62 5,0 5,0 5,0

Preservative 0.5 0.5 0.5

Talc Pharma G 10 10 10

Perfume 1, 2 1, 2 1, 2

2-Benzylheptan-1-ol - 0.3 0.3

Sensiva SC 50 0.6 0.6 0.6

Bovine serum albumin (BSA) 2.0 3.0 5.0

1, 2-propanediol 10 10 10

Water, fully desalted ad 100 ad 100 ad 100

Antiperspirant cosmetic agents according to the invention in the form of microemulsions (in% by weight)

Antiperspirant cosmetic compositions according to the invention in the form of roll-ons (amounts in% by weight)

13 14 15 16 17

Ethanol 96%, (DEP denatured) 30 30 28 28 30

Mergital® CS 1 1 2.0 2.0 - - 2.0

Eumulgin® B3 2.0 2.0 2.0 2.0 2.0

Emulgin® B1 - - 2.0 2.0 - Preservative 0.50 0.50 0.50 0.50 0.50

Hydroxyethylcellulose 0.50 0.50 0.30 0.30 0.50

Bovine serum albumin (BSA) 2.5 0.50 2.0 1, 5 10.0

EDTA - - - 0.050 -

Cocamidopropyl PG-Dimonium Chloride 0.20 - - - 0.20

Phosphate

Perfume oil 0.80 0.80 1, 0 1, 0 0.80

Water ad 100 ad 100 ad 100 ad 100 ad 100

Antiperspirant wipes (Examples Nos. 18 to 21)

For the embodiment according to the invention as an antiperspirant cloth, a single-layer substrate of 100% viscose having a weight per unit area of 50 g / m ^{2 was applied} to 75 g each of the exemplary emulsions 13 or 14 per square meter or 75 g each of the exemplary compositions 10 and 11, respectively , cut into cloths of suitable size and packed in sachets.

Antiperspirant cosmetic agents according to the invention in the form of a water-in-oil emulsion (amounts in% by weight)

Antiperspirant cosmetic agents according to the invention with a pH of 3.0 to 5.0 (amounts in% by weight)

Antiperspirant cosmetic agents according to the invention (amounts in% by weight, based on the total weight of the blowing agent-free composition)

Example Compositions 29-32 were packed in an optionally epoxy-phenolic varnish-sprayed aluminum spray can in a weight ratio of propellant (butane / propane / isobutane mixture) to suspension of 80:20, 85:15, 60:40 and 90:10, respectively.

33 34 35

Preservative 0.500 1, 00 1, 50

Cio-Ci3-Isoalkane 8,90 8,90 8,90

Dow Corning ES-5227 DM 1, 40 1, 40 1, 40

Isoceteth-20 0.500 0.500 0.500

Dimethicone 4,20 4,20 4,20

Isopropyl myristate 9.00 9.00 9.00

1, 2 Propanediol 7.00 25.0 25.0

Phenoxyethanol 0.500 0.500 0.500 Perfume 2.50 2.50 2.50

Bovine serum albumin (BSA) 2.00 0.500 10.0

L-menthol 0.400 0.300 - trans-anethole 0.300

Eucalyptol - 0.300 -

Water ad 100 ad 100 ad 100

Example compositions 33-35 were charged to an aluminum spray can optionally coated with epoxy-phenolic paint in a weight ratio of propellant (butane / propane / isobutane mixture) to suspension of 80:20, 85:15, 60:40 and 90:10, respectively.

Antiperspirant cosmetic agents according to the invention in the form of O / W emulsions (amounts in parts by weight)

Phenoxyethanol 0.500 0.500 0.500 0.500

Perfume 2.50 2.50 2.50 2.50

Water add 100 add 100 add 100 add 100

Example Compositions 39-42 were packed into an optionally epoxy-phenolic varnish-sprayed aluminum spray can in a weight ratio of propellant (butane / propane / isobutane mixture) to suspension of 80:20, 85:15, 60:40 and 90:10, respectively.

Antiperspirant cosmetic compositions according to the invention in the form of W / O emulsions (amounts in% by weight)

The following commercial products were used:

Commercial product INCI Supplier / Manufacturer

Abil EM 90 CETYL PEG / PPG-10/1 Dimethicone Evonik

Abil EM 97 Bis-PEG / PPG-14/14 Dimethicone, Evonik

Cyclomethicone

Abil K 4 Cyclomethicone Goldschmidt

Arlamol E PPG-15 Stearyl ether Croda

Bentone 38 V CG Disteardimonium Hectorite Elementis

Specialties

Brij IC 20 lsoceteth-20 Croda

Brij S 2 Steareth-2 Croda

Brij S 721 Steareth-21 Croda

Cutina ^® CP Cetyl Palmitate BASF

Cutina ^® FS45 Palmitic Acid, Stearic Acid BASF

Cutina ^® HR Hydrogenated Castor Oil BASF Dow ^Corning® 245 cyclopentasiloxane Dow Corning

Dow ^Corning® 2501 bis-PEG-18 methyl ether dimethyl silane Dow Corning

Dow Corning ES-5227 DM dimethicone, PEG / PPG-18/18 Dimethicone at Dow Corning

Weight ratio 3: 1

Dry Flo PC Aluminum Starch Octenylsuccinate National Starch

Eumulgin ^® B1 Ceteareth-12 BASF

Eumulgin B2 Ceteareth-20 ^® BASF

Eumulgin ^® B3 Ceteareth-30 BASF

Kester wax K62 Cetearyl Behenate Koster Keunen

Finsolv TN C12-15 Alkyl Benzoate Innospec

Locron L (AS = 50%) Aluminum Chlorohydrate Clariant

Mergital ^® CS 1 1 Ceteareth-11 BASF

Novata ^® AB Cocoglycerides (melting point 30-32 ° C) BASF

Plantar ^® 1200 Lauryl Glucoside, about 50% AS BASF

Plantar ^® 2000 DECYL GLUCOSIDE, about 50% AS BASF

Sensiva ^® SC 50 2-ethylhexyl glycerol ether Schülke & Mayr

Claims

claims:

1. antiperspirant cosmetic agent containing

(c) at least one substance selected from the group of cosmetic oils used in the

20 ° C and 1 .013 hPa are liquid, fragrances and waxes, and

a) bovine serum albumin (BSA),

wherein the antiperspirant cosmetic agent contains no aluminum-containing compounds.

2. Antiperspirant cosmetic agent according to claim 1, characterized in that the at 20 ° C and 1 .013 hPa liquid cosmetic oil selected from the group of

(iv) nonvolatile non-silicone oils, in particular the esters of linear or branched saturated or unsaturated C 2 to C fatty acids having linear or branched saturated or unsaturated C 2 to C 30 fatty acids which may be hydroxylated, C 8 to C 22 fatty alcohol esters of monovalent or polyvalent C 2 to C fatty acids. C7-hydroxycarboxylic acids, the triethyl citrates, the branched saturated or unsaturated C6-3o-fatty alcohols, the mono-, di- and triglycerides of linear or branched, saturated or unsaturated, optionally hydroxylated Cs-3o-fatty acids, the dicarboxylic acid esters of linear or branched C2 -Cio-alkanols, the addition products of ethylene oxide and / or propylene oxide to mono- or polyhydric C3.22 alkanols, which may be esterified, the symmetrical, asymmetric or cyclic esters of carbonic acid with fatty alcohols, the esters of dimers of unsaturated Ci2-22 Fatty acids with monovalent, linear, branched and cyclic C2 -is-alkanols or C2-6-alkanols, the benzoic acid esters of linear or branched Cs-22-alkanols such as benzoic acid Ci2 -15-alkyl esters and isostearyl benzoate and octyl dodecyl benzoate, the synthetic hydrocarbons such as polyisobutene and polydecenes, the alicyclic hydrocarbons; such as

(v) their mixtures.

3. antiperspirant cosmetic agent according to one of claims 1 or 2, characterized in that the at 20 ° C and 1 .013 hPa liquid cosmetic oil in a Total amount of from 1 to 95% by weight, preferably from 10 to 85% by weight, preferably from 20 to 75% by weight, more preferably from 35 to 70% by weight, in particular from 50 to 60% by weight , based on the total weight of the antiperspirant cosmetic agent.

4. antiperspirant cosmetic agent according to any one of the preceding claims, characterized in that the at 20 ° C and 1 .013 hPa liquid cosmetic oil in a total amount of 0.2 to 70 wt .-%, preferably from 2 to 60 wt. %, preferably from 3 to 50 wt .-%, more preferably from 5 to 35 wt .-%, in particular from 8 to 20 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included.

5. Antiperspirant cosmetic agent according to one of the preceding claims, characterized in that the perfume in a total amount of 0.00001 to 10 wt .-%, preferably from 0.001 to 9 wt .-%, preferably from 0.01 to 8 wt. -%, more preferably from 0.5 to 7 wt .-%, in particular from 1 to 6 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included.

6. antiperspirant cosmetic agent according to one of the preceding claims, characterized in that the wax in a total amount of 0.01 to 50 wt .-%, preferably from 3 to 40 wt .-%, preferably from 5 to 35 wt .-% , in particular from 6 to 25 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included.

7. Antiperspirant cosmetic agent according to one of the preceding claims, characterized in that bovine serum albumin (BSA) in a total amount of 0.05 to 15% by weight, preferably from 0.1 to 10 wt .-%, preferably from 0 , 3 to 5 wt .-%, more preferably from 0.5 to 7 wt .-%, still more preferably from 0.8 to 5 wt .-%, in particular from 1 to 3 wt .-%, based on the total weight of the antiperspirant cosmetic agent.

8. antiperspirant cosmetic agent according to one of the preceding claims, characterized in that the antiperspirant cosmetic agent free water in a total amount of 15 to 96 wt .-%, preferably from 25 to 80 wt .-%, preferably from 30 to 70 wt. -%, In particular from 40 to 60 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains.

9. antiperspirant cosmetic agent according to one of the preceding claims, characterized in that the antiperspirant cosmetic agent ethanol in a total amount of 1 to 50 wt .-%, preferably from 5 to 40 wt .-%, preferably from 7 to 35 parts by weight. % in particular from 10 to 30% by weight, based on the total weight of the antiperspirant cosmetic agent.

10. Use of a combination of at least one selected from the group of cosmetic oils which are liquid at 20 ° C and 1013 hPa, fragrances and waxes, and bovine serum albumin (BSA) for the reduction and / or prevention of perspiration.

11. A non-therapeutic cosmetic method for preventing and / or reducing the transpiration of the body, in which an antiperspirant cosmetic agent according to any one of claims 1 to 9 is applied to the skin, in particular to the skin of the armpits.

12. Use of bovine serum albumin (BSA) to at least partially occlude the sweat gland (s)