CZ154699A3 - N-vázané močoviny a karbamáty heterocyklických thioesterů - Google Patents

N-vázané močoviny a karbamáty heterocyklických thioesterů Download PDF

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Publication number
CZ154699A3
CZ154699A3 CZ991546A CZ154699A CZ154699A3 CZ 154699 A3 CZ154699 A3 CZ 154699A3 CZ 991546 A CZ991546 A CZ 991546A CZ 154699 A CZ154699 A CZ 154699A CZ 154699 A3 CZ154699 A3 CZ 154699A3
Authority
CZ
Czechia
Prior art keywords
alkyl
alkenyl
linear
group
branched
Prior art date
Application number
CZ991546A
Other languages
Czech (cs)
English (en)
Inventor
Gregory S. Hamilton
Jia-He Li
Wei Huang
Original Assignee
Guilford Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guilford Pharmaceuticals Inc. filed Critical Guilford Pharmaceuticals Inc.
Publication of CZ154699A3 publication Critical patent/CZ154699A3/cs

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
CZ991546A 1996-12-31 1997-12-23 N-vázané močoviny a karbamáty heterocyklických thioesterů CZ154699A3 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/775,585 US5935989A (en) 1996-12-31 1996-12-31 N-linked ureas and carbamates of heterocyclic thioesters
PCT/US1997/024070 WO1998029117A1 (en) 1996-12-31 1997-12-23 N-linked ureas and carbamates of heterocyclic thioesters

Publications (1)

Publication Number Publication Date
CZ154699A3 true CZ154699A3 (cs) 1999-11-17

Family

ID=25104858

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ991546A CZ154699A3 (cs) 1996-12-31 1997-12-23 N-vázané močoviny a karbamáty heterocyklických thioesterů

Country Status (15)

Country Link
US (2) US5935989A (US06184243-20010206-C00009.png)
KR (1) KR20000057488A (US06184243-20010206-C00009.png)
AR (1) AR013909A1 (US06184243-20010206-C00009.png)
AU (1) AU721572B2 (US06184243-20010206-C00009.png)
BG (1) BG103408A (US06184243-20010206-C00009.png)
BR (1) BR9714092A (US06184243-20010206-C00009.png)
CA (1) CA2239781A1 (US06184243-20010206-C00009.png)
CZ (1) CZ154699A3 (US06184243-20010206-C00009.png)
GT (1) GT199800014A (US06184243-20010206-C00009.png)
HU (1) HUP0002442A3 (US06184243-20010206-C00009.png)
IL (1) IL129696A0 (US06184243-20010206-C00009.png)
PA (1) PA8444001A1 (US06184243-20010206-C00009.png)
PL (1) PL334372A1 (US06184243-20010206-C00009.png)
WO (1) WO1998029117A1 (US06184243-20010206-C00009.png)
ZA (1) ZA9711704B (US06184243-20010206-C00009.png)

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US6242468B1 (en) * 1997-02-27 2001-06-05 Jia-He Li Carbamate and urea compositions and neurotrophic uses
AU764073B2 (en) * 1997-06-04 2003-08-07 Gpi Nil Holdings, Inc. N-linked urea or carbamate of heterocyclic thioester hair growth compositions and uses
KR20010052502A (ko) * 1998-06-03 2001-06-25 다니엘 피. 맥컬럼 Ｎ-헤테로사이클릭 카복실산 및 카복실산 등입체의 요소및 카르밤산염
ATE268772T1 (de) 1998-07-17 2004-06-15 Agouron Pharma Verbindungen und zusammensetzungen um neurales wachstum und streckung zu stimulieren
US6399648B1 (en) * 1998-08-14 2002-06-04 Gpi Nil Holdings, Inc. N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders
US6506788B1 (en) * 1998-08-14 2003-01-14 Gpi Nil Holdings, Inc. N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders
US6337340B1 (en) * 1998-08-14 2002-01-08 Gpi Nil Holdings, Inc. Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders
US7265150B1 (en) * 1998-08-14 2007-09-04 Gpi Nil Holdings Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders
US6228872B1 (en) 1998-11-12 2001-05-08 Bristol-Myers Squibb Company Neurotrophic diamide and carbamate agents
AU5606400A (en) 1999-07-09 2001-01-30 Ortho-Mcneil Pharmaceutical, Inc. Neurotrophic tetrahydroisoquinolines and tetrahydrothienopyridines, and related compositions and methods
AU5483500A (en) 1999-07-09 2001-01-30 Ortho-Mcneil Pharmaceutical, Inc. Neurotrophic 2-azetidinecarboxylic acid derivatives, and related compositions and methods
BR0012327A (pt) * 1999-07-09 2002-07-02 Ortho Mcneil Pharm Inc Pirrolidinas e piperidinas neurotróficas, e composições e métodos relacionados
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
CO5261615A1 (es) 1999-12-01 2003-03-31 Agouron Pharma Compuestos, composiciones y metodos para estimular el crecimiento y elongacion de neuronas
US6818643B1 (en) 1999-12-08 2004-11-16 Bristol-Myers Squibb Company Neurotrophic bicyclic diamides
ATE319712T1 (de) 1999-12-21 2006-03-15 Mgi Gp Inc Hydantoin derivate, pharmazeutische zusammensetzungen und verfahren zu ihrer verwendung
KR20200089219A (ko) * 2019-01-15 2020-07-24 보로노이 주식회사 아릴 또는 헤테로아릴 유도체, 및 이를 유효성분으로 포함하는 키나아제 관련 질환 치료용 약학적 조성물

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Also Published As

Publication number Publication date
KR20000057488A (ko) 2000-09-15
BG103408A (en) 2000-01-31
AU5724198A (en) 1998-07-31
AR013909A1 (es) 2001-01-31
ZA9711704B (en) 1998-09-23
GT199800014A (es) 1999-07-13
BR9714092A (pt) 2000-05-09
AU721572B2 (en) 2000-07-06
HUP0002442A2 (hu) 2000-12-28
PL334372A1 (en) 2000-02-28
CA2239781A1 (en) 1998-06-30
IL129696A0 (en) 2000-02-29
US6184243B1 (en) 2001-02-06
US5935989A (en) 1999-08-10
WO1998029117A1 (en) 1998-07-09
HUP0002442A3 (en) 2001-01-29
PA8444001A1 (es) 2000-05-24

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic