CY282A - Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts - Google Patents

Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts

Info

Publication number
CY282A
CY282A CY28264A CY28264A CY282A CY 282 A CY282 A CY 282A CY 28264 A CY28264 A CY 28264A CY 28264 A CY28264 A CY 28264A CY 282 A CY282 A CY 282A
Authority
CY
Cyprus
Prior art keywords
alpha
carboxylic acids
aliphatic carboxylic
arylimino
aryloxy
Prior art date
Application number
CY28264A
Other languages
English (en)
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of CY282A publication Critical patent/CY282A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CY28264A 1958-06-20 1964-03-27 Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts CY282A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19793/58A GB860303A (en) 1958-06-20 1958-06-20 Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª

Publications (1)

Publication Number Publication Date
CY282A true CY282A (en) 1964-03-27

Family

ID=10135310

Family Applications (1)

Application Number Title Priority Date Filing Date
CY28264A CY282A (en) 1958-06-20 1964-03-27 Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts

Country Status (5)

Country Link
US (1) US3262850A (en(2012))
BE (1) BE645649A (en(2012))
CY (1) CY282A (en(2012))
GB (1) GB860303A (en(2012))
MY (1) MY6400061A (en(2012))

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097139A (en) * 1960-03-10 1963-07-09 Ici Ltd Hypocholesterolaemia compositions
BE630211A (en(2012)) * 1962-03-28
GB992152A (en) * 1962-07-11 1965-05-19 Prodotti Schering Soc It Aminoesters
US3332842A (en) * 1963-08-30 1967-07-25 Ciba Geigy Corp Ether acids and derivatives thereof
US3332957A (en) * 1964-09-02 1967-07-25 Ciba Geigy Corp Amino esters of substituted phenoxy acetic acids
BE674556A (en(2012)) * 1965-01-05 1966-06-30
US3452081A (en) * 1965-05-27 1969-06-24 Merck & Co Inc Phenoxy substituted 2-alkenoic acids
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
US3538227A (en) * 1967-01-30 1970-11-03 Ciba Geigy Corp Tricyclic phenoxy-acid and ester hypocholesterolemic compositions
SE344742B (en(2012)) * 1968-09-25 1972-05-02 Ciba Geigy Ag
US4031134A (en) * 1969-04-16 1977-06-21 Sumitomo Chemical Company, Limited Phenoxy carboxylic acid derivative
US3716583A (en) * 1969-04-16 1973-02-13 Sumitomo Chemical Co Phenoxy carboxylic acid derivative
FR2043488A1 (en(2012)) * 1969-05-29 1971-02-19 Roussel Uclaf
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
GB1348642A (en) * 1970-10-15 1974-03-20 Howard A N Hypocholesterolaemic compositions
FR2108980A1 (en) * 1970-10-27 1972-05-26 Biosedra Lab Pure ethyl alpha-p-iodophenoxyisobutyrate - with hypolipaemic activity
FR2126077A1 (en) * 1971-02-23 1972-10-06 Lafon Victor Ethyl (3, 5-diethoxy-phenoxy)isobutyrate - as hypocholesteremic
JPS575214B2 (en(2012)) * 1972-06-01 1982-01-29
US3952096A (en) * 1973-06-15 1976-04-20 Bristol-Myers Company Mixture of calcium carbonate and calcium-α-p-chlorophenoxyisobutyrate as an antihyperlipemic agent
DE2342118C2 (de) * 1973-08-21 1982-09-23 Merck Patent Gmbh, 6100 Darmstadt Phenoxypropionsäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
US4039683A (en) * 1973-08-21 1977-08-02 Merck Patent Gesellschaft Mit Beschrankter Haftung Phenoxypropionic acid derivatives and pharmaceutical preparations containing same
US4182902A (en) * 1973-12-27 1980-01-08 Siegfried Aktiengesellschaft Novel cholesterol-lowering compounds
CH617417A5 (en(2012)) * 1973-12-27 1980-05-30 Siegfried Ag
AT353776B (de) * 1973-12-27 1979-12-10 Siegfried Ag Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen
NL7416412A (nl) * 1973-12-27 1975-07-01 Siegfried Ag Werkwijze ter bereiding van nieuwe cholesterol- gende verbindingen.
US4012523A (en) * 1974-01-24 1977-03-15 The Dow Chemical Company Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-(thio or sulfonyl) alkanoic acids and derivatives
US4067998A (en) * 1974-02-11 1978-01-10 The Dow Chemical Company 2-((3,5-Di-tert-butylphenyl)thio) alkanoic acids and derivatives
DK115374A (en(2012)) 1974-03-04 1975-11-03 Byk Gulden Lomberg Chem Fab
US4243819A (en) * 1978-02-16 1981-01-06 Zoecon Corporation Substituted amino acids
US4250191A (en) * 1978-11-30 1981-02-10 Edwards K David Preventing renal failure
JPS58150563A (ja) * 1982-03-04 1983-09-07 Taisho Pharmaceut Co Ltd ３−ベンゾイル−２−メルカプトプロピオン酸誘導体
US4704402A (en) * 1982-06-12 1987-11-03 University Of Pittsburgh Method of treating sickle cell anemia
US4482571A (en) * 1982-06-21 1984-11-13 University Of Pittsburgh Sickle cell anemia treatment and compound
IN160141B (en(2012)) * 1983-05-09 1987-06-27 Council Scient Ind Res
EP0320501A3 (en) * 1983-06-24 1989-12-06 Yamanouchi Pharmaceutical Co., Ltd. Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them
ES533668A0 (es) * 1983-06-24 1985-10-01 Yamanouchi Pharma Co Ltd Un compuesto fenoxi
DE3621861A1 (de) * 1986-06-30 1988-01-14 Laszlo Dr Med Ilg Verwendung von aryloxycarbonsaeure-derivaten gegen dermatologische erkrankungen
US4859703A (en) * 1987-06-15 1989-08-22 Warner-Lambert Company Lipid regulating compositions
WO1991011994A1 (en) * 1990-02-14 1991-08-22 Chugai Seiyaku Kabushiki Kaisha Inhibitor of denatured ldl formation
US6262277B1 (en) * 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
ATE234084T1 (de) 1998-06-02 2003-03-15 Arthromics Plc Substanzen, die mit dem thyroid-hormonrezeptor interagieren, zur behandlung fibrotischer erkrankungen
WO2000038721A1 (en) 1998-12-23 2000-07-06 G.D. Searle Llc Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications
WO2000038722A1 (en) 1998-12-23 2000-07-06 G.D. Searle & Co. COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS
ATE242009T1 (de) 1998-12-23 2003-06-15 Searle Llc Kombinationen von cholesteryl ester transfer protein inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen
EP1336413A1 (en) * 1998-12-23 2003-08-20 G.D. Searle LLC. Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications
ES2203239T3 (es) 1998-12-23 2004-04-01 G.D. Searle Llc Combinaciones de inhibidores de la proteina de transferencia de ester de colesterilo y de agentes secuestrantes de acidos biliares para indicaciones cardiovasculares.
ATE228012T1 (de) * 1998-12-23 2002-12-15 Searle Llc Kombinationen von ileumgallensäuretransports inhibitoren und gallensäure sequestriermitteln für kardiovaskuläre indikationen
EA200100704A1 (ru) * 1998-12-23 2002-02-28 Джи.Ди.Сирл Ллс Комбинация для применения по сердечно-сосудистым показаниям
MXPA01006471A (es) * 1998-12-23 2004-03-10 Searle Llc Combinaciones de inhibidores de transporte de acido biliar ileal e inhibidores de proteina de transferencia de ester colesterilio cpara indicaciones cardiovasculares.
US20020061888A1 (en) * 2000-03-10 2002-05-23 Keller Bradley T. Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
EP1286984A2 (en) 2000-03-10 2003-03-05 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US20040077625A1 (en) * 2001-07-25 2004-04-22 Tremont Samuel J. Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
BR0213501A (pt) * 2001-11-02 2004-08-24 Searle Llc Compostos de benzotiepina mono- e di-fluorada como inibidores de transporte de ácido biliar co-dependente de sódio apical (asbt) e captação de taurocolato
CA2471639A1 (en) 2002-01-17 2003-07-31 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
ITRM20020629A1 (it) * 2002-12-19 2004-06-20 Sigma Tau Ind Farmaceuti Uso di acidi alfa-feniltiocarbossilici e alfa-fenilossicarbossilici ad attivita' ipoglicemizzante e/o ipolipidemizzante.
US7601756B2 (en) * 2003-06-06 2009-10-13 Snowden Pharmaceuticals, Llc Method of treatment for irritable bowel syndrome
EP1680099B1 (en) * 2003-11-07 2009-04-15 JJ Pharma, Inc. Hdl-boosting combination therapy complexes
US20070190079A1 (en) * 2004-10-29 2007-08-16 Kalypsys, Inc. Methods for the selective modulation of ppar
FR2880887B1 (fr) * 2005-01-14 2009-01-30 Merck Sante Soc Par Actions Si Derives d'hydroxyphenols, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
WO2008045564A2 (en) * 2006-10-12 2008-04-17 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
WO2008112166A2 (en) 2007-03-09 2008-09-18 Indigene Pharmaceuticals Inc. Combination of metformin r-(+) lipoate and antihyperlipidemic agents for the treatment of diabetic hyperglycemia and diabetic complications
WO2008157537A2 (en) * 2007-06-19 2008-12-24 Ironwood Pharmaceuticals, Inc Compositions and methods of use for treating or preventing lipid related disorders
WO2009076404A1 (en) * 2007-12-10 2009-06-18 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
BRPI0820701A2 (pt) 2007-12-11 2015-06-16 Cytopathfinder Inc Composto de carboxamida e seu uso como agonistas do receptor de quimiocina
MX2012001520A (es) 2009-08-03 2012-06-01 Acraf Proceso para la preparacion de 1-bencil-3-hidroximetil-1h-indazol y sus derivados e intermediarios de magnesio requeridos.
EA036404B1 (ru) 2015-02-06 2020-11-06 Интерсепт Фармасьютикалз, Инк. Фармацевтические композиции для комбинированной терапии
KR101956805B1 (ko) * 2019-02-21 2019-03-11 한국식품연구원 부테인 또는 이소유제놀을 포함하는 pcsk9 유전자의 발현 감소 또는 저밀도 지단백 수용체 증가용 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2580653A (en) * 1946-08-23 1952-01-01 Johnson & Son Inc S C Composition for killing weeds
US2937117A (en) * 1953-06-19 1960-05-17 Chimie Atomistique Process for lowering high blood cholesterol levels
US2957760A (en) * 1957-11-19 1960-10-25 Amchem Prod Process for thinning stone fruits with alpha-(3-chlorophenoxy)-propionic acid and its salts and esters

Also Published As

Publication number Publication date
MY6400061A (en) 1964-12-31
BE645649A (en(2012)) 1964-07-16
GB860303A (en) 1961-02-01
US3262850A (en) 1966-07-26

Similar Documents

Publication Publication Date Title
CY282A (en) Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts
IL29769A0 (en) Production of carboxylic acids and esters
MY6400024A (en) Herbicidal dichlorganilides of carboxylic acids and their preparation and use
CA557568A (en) Substituted aminopyrrolecarboxylic acids and esters
IL24463A (en) Tropanyl and quinuclidinyl esters of dibenzocycloheptene and 10,11-dihydro-dibenzocycloheptene carboxylic acids and their preparation
CA618072A (en) Carboxylic acids of the pyrazole series and their esters and salts
CA565765A (en) Salts of sulfoloweralkyl esters of chloroaryloxy-lower-aliphatic-monocarboxylic acids
AU267589B2 (en) N-acylhydroxy-aminoacetic acids and salts and esters thereof
CA611472A (en) Esters of carbonilic acids
CA517098A (en) Seleno fatty acids and salts and esters thereof
AU1465062A (en) N-acylhydroxy-aminoacetic acids and salts and esters thereof
AU255573B2 (en) Esters of disocyanato carboxylic acids
CA584406A (en) Dimeric fatty acids and esters thereof
IE24104L (en) Polyene carboxylic acids and esters.
IL31046A0 (en) Fluoroethanol esters of aromatic carboxylic acids and their use as pesticides
CA556124A (en) Compositions containing esters of a glycol and polycarboxylic acids
AU266509B2 (en) New acids and esters thereof and process for their manufacture
AU268039B2 (en) Basic esters of pentifluorophenyl-substituted carboxylic acids
AU232045B2 (en) Pregnene-21-oxalo acid esters and derivatives thereof
CA568085A (en) Esters of dithiolanyl aliphatic acids
AU1134261A (en) Esters of disocyanato carboxylic acids
IL29734A0 (en) Chloroalkylthiolphosphoric acid esters of ester amides
CA572374A (en) Acyloxy-halo derivatives of aliphatic acids and their esters
CA542819A (en) Esters of vinyloxyalkoxy compounds and unsaturated carboxylic acids
CA565557A (en) Preparation of carboxylic acids