CY282A - Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts - Google Patents

Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts

Info

Publication number
CY282A
CY282A CY28264A CY28264A CY282A CY 282 A CY282 A CY 282A CY 28264 A CY28264 A CY 28264A CY 28264 A CY28264 A CY 28264A CY 282 A CY282 A CY 282A
Authority
CY
Cyprus
Prior art keywords
alpha
carboxylic acids
aliphatic carboxylic
arylimino
aryloxy
Prior art date
Application number
CY28264A
Other languages
English (en)
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of CY282A publication Critical patent/CY282A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CY28264A 1958-06-20 1964-03-27 Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts CY282A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19793/58A GB860303A (en) 1958-06-20 1958-06-20 Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª

Publications (1)

Publication Number Publication Date
CY282A true CY282A (en) 1964-03-27

Family

ID=10135310

Family Applications (1)

Application Number Title Priority Date Filing Date
CY28264A CY282A (en) 1958-06-20 1964-03-27 Pharmaceutical compositions comprising alpha-aryloxy-aliphatic carboxylic acids and/or alpha-arylimino-aliphatic carboxylic acids their esters and salts

Country Status (5)

Country Link
US (1) US3262850A (enrdf_load_html_response)
BE (1) BE645649A (enrdf_load_html_response)
CY (1) CY282A (enrdf_load_html_response)
GB (1) GB860303A (enrdf_load_html_response)
MY (1) MY6400061A (enrdf_load_html_response)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097139A (en) * 1960-03-10 1963-07-09 Ici Ltd Hypocholesterolaemia compositions
BE630211A (enrdf_load_html_response) * 1962-03-28
GB992152A (en) * 1962-07-11 1965-05-19 Prodotti Schering Soc It Aminoesters
US3332842A (en) * 1963-08-30 1967-07-25 Ciba Geigy Corp Ether acids and derivatives thereof
US3332957A (en) * 1964-09-02 1967-07-25 Ciba Geigy Corp Amino esters of substituted phenoxy acetic acids
SE337383B (enrdf_load_html_response) * 1965-01-05 1971-08-09 Yoshitomi Pharmaceutical
US3452081A (en) * 1965-05-27 1969-06-24 Merck & Co Inc Phenoxy substituted 2-alkenoic acids
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
US3538227A (en) * 1967-01-30 1970-11-03 Ciba Geigy Corp Tricyclic phenoxy-acid and ester hypocholesterolemic compositions
SE344742B (enrdf_load_html_response) * 1968-09-25 1972-05-02 Ciba Geigy Ag
US4031134A (en) * 1969-04-16 1977-06-21 Sumitomo Chemical Company, Limited Phenoxy carboxylic acid derivative
FI52570C (fi) * 1969-04-16 1977-10-10 Sumitomo Chemical Co Menetelmä veren kolesteroli- tai lipoidipitoisuutta alentavien fenoxia lifaattisten karboksyylihappoyhdisteiden ja -esteriyhdisteiden valmist amiseksi.
FR2043488A1 (enrdf_load_html_response) * 1969-05-29 1971-02-19 Roussel Uclaf
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
GB1348642A (en) * 1970-10-15 1974-03-20 Howard A N Hypocholesterolaemic compositions
FR2108980A1 (en) * 1970-10-27 1972-05-26 Biosedra Lab Pure ethyl alpha-p-iodophenoxyisobutyrate - with hypolipaemic activity
FR2126077A1 (en) * 1971-02-23 1972-10-06 Lafon Victor Ethyl (3, 5-diethoxy-phenoxy)isobutyrate - as hypocholesteremic
JPS575214B2 (enrdf_load_html_response) * 1972-06-01 1982-01-29
US3952096A (en) * 1973-06-15 1976-04-20 Bristol-Myers Company Mixture of calcium carbonate and calcium-α-p-chlorophenoxyisobutyrate as an antihyperlipemic agent
DE2342118C2 (de) * 1973-08-21 1982-09-23 Merck Patent Gmbh, 6100 Darmstadt Phenoxypropionsäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
US4039683A (en) * 1973-08-21 1977-08-02 Merck Patent Gesellschaft Mit Beschrankter Haftung Phenoxypropionic acid derivatives and pharmaceutical preparations containing same
CH617417A5 (enrdf_load_html_response) * 1973-12-27 1980-05-30 Siegfried Ag
US4182902A (en) * 1973-12-27 1980-01-08 Siegfried Aktiengesellschaft Novel cholesterol-lowering compounds
AT353776B (de) * 1973-12-27 1979-12-10 Siegfried Ag Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen
NL7416412A (nl) * 1973-12-27 1975-07-01 Siegfried Ag Werkwijze ter bereiding van nieuwe cholesterol- gende verbindingen.
US4012523A (en) * 1974-01-24 1977-03-15 The Dow Chemical Company Hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-(thio or sulfonyl) alkanoic acids and derivatives
US4067998A (en) * 1974-02-11 1978-01-10 The Dow Chemical Company 2-((3,5-Di-tert-butylphenyl)thio) alkanoic acids and derivatives
DK115374A (enrdf_load_html_response) 1974-03-04 1975-11-03 Byk Gulden Lomberg Chem Fab
US4243819A (en) * 1978-02-16 1981-01-06 Zoecon Corporation Substituted amino acids
US4250191A (en) * 1978-11-30 1981-02-10 Edwards K David Preventing renal failure
JPS58150563A (ja) * 1982-03-04 1983-09-07 Taisho Pharmaceut Co Ltd ３−ベンゾイル−２−メルカプトプロピオン酸誘導体
US4704402A (en) * 1982-06-12 1987-11-03 University Of Pittsburgh Method of treating sickle cell anemia
US4482571A (en) * 1982-06-21 1984-11-13 University Of Pittsburgh Sickle cell anemia treatment and compound
IN160141B (enrdf_load_html_response) * 1983-05-09 1987-06-27 Council Scient Ind Res
EP0320501A3 (en) * 1983-06-24 1989-12-06 Yamanouchi Pharmaceutical Co., Ltd. Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them
ES8600261A1 (es) * 1983-06-24 1985-10-01 Yamanouchi Pharma Co Ltd Un compuesto fenoxi
DE3621861A1 (de) * 1986-06-30 1988-01-14 Laszlo Dr Med Ilg Verwendung von aryloxycarbonsaeure-derivaten gegen dermatologische erkrankungen
US4859703A (en) * 1987-06-15 1989-08-22 Warner-Lambert Company Lipid regulating compositions
WO1991011994A1 (en) * 1990-02-14 1991-08-22 Chugai Seiyaku Kabushiki Kaisha Inhibitor of denatured ldl formation
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6348497B1 (en) 1998-06-02 2002-02-19 Arthromics Plc Compounds which interact with the thyroid hormone receptor for the treatment of fibrotic disease
EP1140186B1 (en) 1998-12-23 2003-06-04 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
DK1140187T3 (da) * 1998-12-23 2003-12-22 Searle Llc Kombinationer af en IBAT-inhibitor og en MTP-inhibitor til cardiovaskulære indikationer
ES2203239T3 (es) 1998-12-23 2004-04-01 G.D. Searle Llc Combinaciones de inhibidores de la proteina de transferencia de ester de colesterilo y de agentes secuestrantes de acidos biliares para indicaciones cardiovasculares.
HK1044292A1 (zh) * 1998-12-23 2002-10-18 G‧D‧瑟尔有限公司 适用於心血管疾病的回肠胆汁酸转运抑制剂和胆汁酸螯合剂组合
ES2201822T3 (es) 1998-12-23 2004-03-16 G.D. Searle Llc Combinaciones de inhibididores de la proteina de transferencia de ester de colesterilo y de derivados de acido nicotinico para indicaciones cardiovasculares.
DK1140189T3 (da) 1998-12-23 2003-09-15 Searle Llc Kombinationer af ileal galdesyre-transportinhibitorer og fibrinsyrederivater til cardiovaskulære indikationer
HUP0201972A3 (en) 1998-12-23 2005-06-28 G D Searle Llc Chicago Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications
AU2157400A (en) 1998-12-23 2000-07-31 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and hmg coa reductase inhibitors for cardiovascular indications
US20020061888A1 (en) * 2000-03-10 2002-05-23 Keller Bradley T. Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
AU2001240115A1 (en) 2000-03-10 2001-09-24 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US20040077625A1 (en) * 2001-07-25 2004-04-22 Tremont Samuel J. Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
CA2464685A1 (en) * 2001-11-02 2003-05-15 G.D. Searle Llc Novel mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (asbt) and taurocholate uptake
CA2471639A1 (en) 2002-01-17 2003-07-31 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
ITRM20020629A1 (it) * 2002-12-19 2004-06-20 Sigma Tau Ind Farmaceuti Uso di acidi alfa-feniltiocarbossilici e alfa-fenilossicarbossilici ad attivita' ipoglicemizzante e/o ipolipidemizzante.
WO2004108126A1 (en) * 2003-06-06 2004-12-16 Snowden Pharmaceuticals, Llc Fibric acid derivatives for the treatment of irritable bowel syndrome
JP4839221B2 (ja) * 2003-11-07 2011-12-21 ジェイ ジェイ ファーマ，インコーポレイテッド Ｈｄｌを高める併用療法用複合物
US20070190079A1 (en) * 2004-10-29 2007-08-16 Kalypsys, Inc. Methods for the selective modulation of ppar
FR2880887B1 (fr) * 2005-01-14 2009-01-30 Merck Sante Soc Par Actions Si Derives d'hydroxyphenols, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
CL2007002958A1 (es) * 2006-10-12 2008-05-09 Epix Delaware Inc Compuestos derivados de heteroaril-carboxamida, antagonistas del receptor de quimioquina; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades tales como rechazo de transplante de organos, artritis reumatoidea, lupus, entr
CL2008000684A1 (es) 2007-03-09 2008-08-01 Indigene Pharmaceuticals Inc Composicion farmaceutica que comprende metformina r-(+) lipoato y un inhibidor de reductasa hmg-coa; formulacion de dosis unitaria; y uso en el tratamiento de una complicacion diabetica.
US20090054450A1 (en) * 2007-06-19 2009-02-26 Ironwood Pharmaceuticals, Inc. Compositions and methods of use for treating or preventing lipid related disorders
US20100331298A1 (en) * 2007-12-10 2010-12-30 Cytopathfinder, Inc. Carboxamide Compounds and Their Use
AU2008335135A1 (en) 2007-12-11 2009-06-18 Cytopathfinder, Inc. Carboxamide compounds and their use as chemokine receptor agonists
GEP20135879B (en) 2009-08-03 2013-07-10 Aziende Chimiche Riunite Angelini Francesco A C R A F S P A It Method of 1-benzyl-3-hydroxymethyl-1h-indazole preparation, derivatives thereof, and required magnesium intermediates
CA2976056C (en) 2015-02-06 2024-02-06 Intercept Pharmaceuticals, Inc. Pharmaceutical compositions for combination therapy
KR101956805B1 (ko) * 2019-02-21 2019-03-11 한국식품연구원 부테인 또는 이소유제놀을 포함하는 pcsk9 유전자의 발현 감소 또는 저밀도 지단백 수용체 증가용 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2580653A (en) * 1946-08-23 1952-01-01 Johnson & Son Inc S C Composition for killing weeds
US2937117A (en) * 1953-06-19 1960-05-17 Chimie Atomistique Process for lowering high blood cholesterol levels
US2957760A (en) * 1957-11-19 1960-10-25 Amchem Prod Process for thinning stone fruits with alpha-(3-chlorophenoxy)-propionic acid and its salts and esters

Also Published As

Publication number Publication date
US3262850A (en) 1966-07-26
GB860303A (en) 1961-02-01
BE645649A (enrdf_load_html_response) 1964-07-16
MY6400061A (en) 1964-12-31

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