CY2018033I2 - Λιποσωμικες φαρμακοτεχνικες μορφες παραγοντων ανθρακυκλινης και αναλογων κυτιδινης - Google Patents
Λιποσωμικες φαρμακοτεχνικες μορφες παραγοντων ανθρακυκλινης και αναλογων κυτιδινηςInfo
- Publication number
- CY2018033I2 CY2018033I2 CY2018033C CY2018033C CY2018033I2 CY 2018033 I2 CY2018033 I2 CY 2018033I2 CY 2018033 C CY2018033 C CY 2018033C CY 2018033 C CY2018033 C CY 2018033C CY 2018033 I2 CY2018033 I2 CY 2018033I2
- Authority
- CY
- Cyprus
- Prior art keywords
- pharmaceutical forms
- liposomal pharmaceutical
- cytidine analogues
- anthracycline agents
- anthracycline
- Prior art date
Links
- 229940045799 anthracyclines and related substance Drugs 0.000 title 1
- UHDGCWIWMRVCDJ-XVFCMESISA-N cytidine Chemical class O=C1N=C(N)C=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-XVFCMESISA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/797—Lipid particle
- Y10S977/798—Lipid particle having internalized material
- Y10S977/799—Containing biological material
- Y10S977/801—Drug
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56521004P | 2004-04-22 | 2004-04-22 | |
| PCT/CA2005/000625 WO2005102359A1 (en) | 2004-04-22 | 2005-04-22 | Liposomal formulations of anthracycline agents and cytidine analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CY2018033I1 CY2018033I1 (el) | 2019-07-10 |
| CY2018033I2 true CY2018033I2 (el) | 2019-07-10 |
Family
ID=35196733
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100616T CY1113012T1 (el) | 2004-04-22 | 2012-07-10 | Λιποσωμικες φαρμακοτεχνικες μορφες παραγοντων ανθρακυκλινης και αναλογων κυτιδινης |
| CY2018033C CY2018033I2 (el) | 2004-04-22 | 2018-12-07 | Λιποσωμικες φαρμακοτεχνικες μορφες παραγοντων ανθρακυκλινης και αναλογων κυτιδινης |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20121100616T CY1113012T1 (el) | 2004-04-22 | 2012-07-10 | Λιποσωμικες φαρμακοτεχνικες μορφες παραγοντων ανθρακυκλινης και αναλογων κυτιδινης |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8022279B2 (el) |
| EP (2) | EP1744764B1 (el) |
| JP (1) | JP4972545B2 (el) |
| AU (1) | AU2005235455B2 (el) |
| BE (1) | BE2018C045I2 (el) |
| CA (1) | CA2564542C (el) |
| CY (2) | CY1113012T1 (el) |
| ES (1) | ES2388064T3 (el) |
| HK (1) | HK1097194A1 (el) |
| IL (1) | IL178779A (el) |
| NL (1) | NL300960I2 (el) |
| PT (1) | PT1744764E (el) |
| WO (1) | WO2005102359A1 (el) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1796689A4 (en) * | 2004-09-20 | 2009-01-14 | British Columbia Cancer Agency | GEMCITABINE FREE OR ENCAPSULATED IN LIPOSOMES ONLY OR IN ASSOCIATION WITH FREE IDARUBICIN OR ENCAPSULATED IN LIPOSOMES |
| EP2279726A3 (en) * | 2005-05-26 | 2012-06-20 | Biorest Ltd. | Compositions and methods using same for delivering agents into a target organ protected by a blood barrier |
| PL3300601T3 (pl) * | 2007-02-16 | 2022-05-02 | Rotalec Ip Holdings Llc | Ustalone stosunki leków do leczenia nowotworów hematopoetycznych i zaburzeń proliferacyjnych |
| US20110021517A1 (en) * | 2008-02-26 | 2011-01-27 | Nerviano Medical Sciences S.R.L. | Antitumor combination comprising a morpholinyl anthracycline derivative and demethylating agents |
| WO2011119995A2 (en) | 2010-03-26 | 2011-09-29 | Cerulean Pharma Inc. | Formulations and methods of use |
| CN101912363A (zh) * | 2010-07-29 | 2010-12-15 | 蔡海德 | 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物 |
| CN104114156A (zh) | 2011-10-21 | 2014-10-22 | 切拉托尔制药公司 | 冻干脂质体 |
| AU2013243873B2 (en) | 2012-04-04 | 2016-08-25 | Halozyme, Inc. | Combination therapy with an anti - hyaluronan agent and a tumor - targeted taxane |
| EP3785720A1 (en) | 2012-05-09 | 2021-03-03 | Cantex Pharmaceuticals, Inc. | Treatment of myelosuppression |
| EP3258941A4 (en) | 2015-02-17 | 2018-09-26 | Cantex Pharmaceuticals, Inc. | Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction |
| EP3291797B1 (en) | 2015-05-04 | 2020-09-02 | Versantis AG | Method for preparing transmembrane ph-gradient vesicles |
| JP6564873B2 (ja) * | 2015-11-02 | 2019-08-21 | 富士フイルム株式会社 | リポソーム組成物およびその製造方法 |
| JP6976941B2 (ja) | 2015-11-11 | 2021-12-08 | セレーター ファーマシューティカルズ インコーポレイテッド | 白血病に罹患している対象の治療レジメンを選択するためのアッセイ及び方法 |
| US12064445B2 (en) | 2015-12-03 | 2024-08-20 | Biosight Ltd. | Cytarabine conjugates for cancer therapy |
| US12071450B2 (en) | 2015-12-03 | 2024-08-27 | Biosight Ltd. | Salts of conjugates for cancer therapy |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| KR20200027548A (ko) * | 2017-07-09 | 2020-03-12 | 바이오사이트 리미티드 | 병용 암 요법 |
| WO2019222435A1 (en) | 2018-05-16 | 2019-11-21 | Halozyme, Inc. | Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20 |
| CN113473980A (zh) | 2019-03-01 | 2021-10-01 | 弗拉梅尔爱尔兰有限公司 | 在进食状态下具有改善的药代动力学的γ-羟基丁酸酯组合物 |
| US11980636B2 (en) | 2020-11-18 | 2024-05-14 | Jazz Pharmaceuticals Ireland Limited | Treatment of hematological disorders |
| CN113181117B (zh) * | 2021-03-22 | 2022-08-26 | 沈阳药科大学 | 一种紫草素和蒽环类化疗药共载脂质体及其制备方法和应用 |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3993754A (en) | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
| US4086257A (en) | 1976-10-12 | 1978-04-25 | Sears Barry D | Phosphatidyl quaternary ammonium compounds |
| CH624011A5 (el) | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4522803A (en) | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
| US4588578A (en) | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
| US5736155A (en) | 1984-08-08 | 1998-04-07 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
| US5077056A (en) * | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
| US5059421A (en) | 1985-07-26 | 1991-10-22 | The Liposome Company, Inc. | Preparation of targeted liposome systems of a defined size distribution |
| MX9203808A (es) | 1987-03-05 | 1992-07-01 | Liposome Co Inc | Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos. |
| US5800833A (en) | 1995-02-27 | 1998-09-01 | University Of British Columbia | Method for loading lipid vesicles |
| GB9613182D0 (en) | 1996-06-24 | 1996-08-28 | Nycomed Imaging As | Method |
| US5837282A (en) | 1996-10-30 | 1998-11-17 | University Of British Columbia | Ionophore-mediated liposome loading |
| US6146659A (en) * | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
| ES2186484B1 (es) | 2000-10-10 | 2004-07-01 | Lipotec, S.A. | Liposomas encapsulando farmacos anticancerosos y uso de los mismos en el tratamiento de tumores malignos. |
| US6613753B2 (en) | 2001-02-21 | 2003-09-02 | Supergen, Inc. | Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation |
| CA2383259A1 (en) * | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
| US7850990B2 (en) * | 2001-10-03 | 2010-12-14 | Celator Pharmaceuticals, Inc. | Compositions for delivery of drug combinations |
| EP1432403B1 (en) * | 2001-10-03 | 2010-07-28 | Celator Pharmaceuticals, Inc. | Liposome loading with metal ions |
| JP2006522026A (ja) | 2003-04-02 | 2006-09-28 | セレーター ファーマスーティカルズ、インク． | カンプトセシンとフルオロピリミジンとを組み合わせた組成物 |
| WO2005000266A2 (en) * | 2003-05-22 | 2005-01-06 | Neopharm, Inc. | Liposomal formulations comprising a combination of two or more active agents |
-
2005
- 2005-04-22 US US11/587,112 patent/US8022279B2/en active Active
- 2005-04-22 EP EP05738885A patent/EP1744764B1/en active Active
- 2005-04-22 WO PCT/CA2005/000625 patent/WO2005102359A1/en active Application Filing
- 2005-04-22 JP JP2007508701A patent/JP4972545B2/ja active Active
- 2005-04-22 CA CA2564542A patent/CA2564542C/en active Active
- 2005-04-22 ES ES05738885T patent/ES2388064T3/es active Active
- 2005-04-22 EP EP11185094A patent/EP2407169A1/en not_active Withdrawn
- 2005-04-22 AU AU2005235455A patent/AU2005235455B2/en active Active
- 2005-04-22 PT PT05738885T patent/PT1744764E/pt unknown
-
2006
- 2006-10-22 IL IL178779A patent/IL178779A/en active IP Right Grant
-
2007
- 2007-05-04 HK HK07104820.1A patent/HK1097194A1/xx unknown
-
2011
- 2011-09-20 US US13/237,807 patent/US8431806B2/en active Active
-
2012
- 2012-07-10 CY CY20121100616T patent/CY1113012T1/el unknown
-
2018
- 2018-11-30 BE BE2018C045C patent/BE2018C045I2/nl unknown
- 2018-12-07 CY CY2018033C patent/CY2018033I2/el unknown
- 2018-12-11 NL NL300960C patent/NL300960I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1113012T1 (el) | 2016-04-13 |
| US8022279B2 (en) | 2011-09-20 |
| WO2005102359A1 (en) | 2005-11-03 |
| CA2564542C (en) | 2012-11-27 |
| US8431806B2 (en) | 2013-04-30 |
| HK1097194A1 (en) | 2007-06-22 |
| CY2018033I1 (el) | 2019-07-10 |
| WO2005102359A8 (en) | 2005-12-15 |
| AU2005235455B2 (en) | 2011-01-20 |
| ES2388064T3 (es) | 2012-10-08 |
| PT1744764E (pt) | 2012-08-30 |
| EP1744764B1 (en) | 2012-05-30 |
| IL178779A (en) | 2013-12-31 |
| JP4972545B2 (ja) | 2012-07-11 |
| NL300960I2 (nl) | 2019-05-22 |
| EP2407169A1 (en) | 2012-01-18 |
| BE2018C045I2 (el) | 2024-08-08 |
| EP1744764A4 (en) | 2009-04-01 |
| CA2564542A1 (en) | 2005-11-03 |
| JP2007533670A (ja) | 2007-11-22 |
| EP1744764A1 (en) | 2007-01-24 |
| AU2005235455A1 (en) | 2005-11-03 |
| US20070286897A1 (en) | 2007-12-13 |
| IL178779A0 (en) | 2007-05-15 |
| US20120009252A1 (en) | 2012-01-12 |
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