CY1125536T1 - Συνθεσεις για τη θεραπεια της αμυλοειδωσης - Google Patents

Συνθεσεις για τη θεραπεια της αμυλοειδωσης

Info

Publication number
CY1125536T1
CY1125536T1 CY20221100542T CY221100542T CY1125536T1 CY 1125536 T1 CY1125536 T1 CY 1125536T1 CY 20221100542 T CY20221100542 T CY 20221100542T CY 221100542 T CY221100542 T CY 221100542T CY 1125536 T1 CY1125536 T1 CY 1125536T1
Authority
CY
Cyprus
Prior art keywords
amyloidosia
compositions
treatment
amyloidosis
patients
Prior art date
Application number
CY20221100542T
Other languages
Greek (el)
English (en)
Inventor
Gene G. Kinney
Spencer D GUTHRIE
Martin Koller
Original Assignee
Prothena Biosciences Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prothena Biosciences Limited filed Critical Prothena Biosciences Limited
Publication of CY1125536T1 publication Critical patent/CY1125536T1/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY20221100542T 2016-06-30 2022-08-08 Συνθεσεις για τη θεραπεια της αμυλοειδωσης CY1125536T1 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662357151P 2016-06-30 2016-06-30

Publications (1)

Publication Number Publication Date
CY1125536T1 true CY1125536T1 (el) 2025-05-09

Family

ID=59351103

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20221100542T CY1125536T1 (el) 2016-06-30 2022-08-08 Συνθεσεις για τη θεραπεια της αμυλοειδωσης

Country Status (16)

Country Link
US (2) US20190169280A1 (enExample)
EP (1) EP3478713B1 (enExample)
JP (3) JP2019519584A (enExample)
CY (1) CY1125536T1 (enExample)
DK (1) DK3478713T3 (enExample)
ES (1) ES2914781T3 (enExample)
HR (1) HRP20220979T8 (enExample)
HU (1) HUE059400T2 (enExample)
LT (1) LT3478713T (enExample)
MA (1) MA45552A (enExample)
PL (1) PL3478713T3 (enExample)
PT (1) PT3478713T (enExample)
RS (1) RS63446B1 (enExample)
SI (1) SI3478713T1 (enExample)
SM (1) SMT202200261T1 (enExample)
WO (1) WO2018005967A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA202092264A1 (ru) * 2018-03-23 2020-12-03 Протена Байосайенсиз Лимитед Лечение и профилактика амилоидоза
EP3923954A1 (en) * 2019-02-12 2021-12-22 Prothena Biosciences Limited Treatment of al amyloidosis with the combination of monoclonal antibodies against immunoglobulin light chains and the cd38 cell membrane molecule on antibody-producing and other immune cells
PH12021552135A1 (en) * 2019-03-05 2022-08-31 Prothena Biosciences Ltd Methods of treating al amyloidosis
EP4022062A1 (en) * 2019-08-30 2022-07-06 Alnylam Pharmaceuticals, Inc. Neurofilament light chain (nfl) as a biomarker for transthyretin amyloidosis polyneuropathy
MX2022016544A (es) * 2020-06-22 2023-04-05 Ngm Biopharmaceuticals Inc Agentes de union a lair-1 y metodos para su uso.
TW202332465A (zh) * 2021-01-29 2023-08-16 愛爾蘭商普羅希那生物科學有限公司 治療al類澱粉變性症之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1355919T3 (da) 2000-12-12 2011-03-14 Medimmune Llc Molekyler med længere halveringstider, sammensætninger og anvendelser deraf
EA028356B1 (ru) 2007-12-28 2017-11-30 Протена Байосайенсиз Лимитед Лечение и профилактика амилоидоза
SG10201604104PA (en) 2011-10-25 2016-07-28 Prothena Therapeutics Ltd Antibody formulations and methods

Also Published As

Publication number Publication date
HRP20220979T8 (hr) 2023-02-03
LT3478713T (lt) 2022-06-10
ES2914781T3 (es) 2022-06-16
EP3478713A1 (en) 2019-05-08
EP3478713B1 (en) 2022-05-11
WO2018005967A1 (en) 2018-01-04
PL3478713T3 (pl) 2022-10-10
SI3478713T1 (sl) 2022-06-30
JP2019519584A (ja) 2019-07-11
RS63446B1 (sr) 2022-08-31
HRP20220979T1 (hr) 2022-11-11
MA45552A (fr) 2019-05-08
JP2024127990A (ja) 2024-09-20
PT3478713T (pt) 2022-05-27
US20190169280A1 (en) 2019-06-06
SMT202200261T1 (it) 2022-07-21
DK3478713T3 (da) 2022-06-20
JP2022121658A (ja) 2022-08-19
US20210079078A1 (en) 2021-03-18
HUE059400T2 (hu) 2022-11-28

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