CY1124538T1 - Χρηση prg4 για τη βελτιωση της δυναμικης οπτικης οξυτητας και εκτροπων υψηλοτερης ταξης - Google Patents
Χρηση prg4 για τη βελτιωση της δυναμικης οπτικης οξυτητας και εκτροπων υψηλοτερης ταξηςInfo
- Publication number
- CY1124538T1 CY1124538T1 CY20211100858T CY211100858T CY1124538T1 CY 1124538 T1 CY1124538 T1 CY 1124538T1 CY 20211100858 T CY20211100858 T CY 20211100858T CY 211100858 T CY211100858 T CY 211100858T CY 1124538 T1 CY1124538 T1 CY 1124538T1
- Authority
- CY
- Cyprus
- Prior art keywords
- prg4
- abirations
- order
- visual acuity
- dynamic visual
- Prior art date
Links
- 101001123332 Homo sapiens Proteoglycan 4 Proteins 0.000 title abstract 2
- 102100028965 Proteoglycan 4 Human genes 0.000 title 1
- 230000004304 visual acuity Effects 0.000 title 1
- 230000004075 alteration Effects 0.000 abstract 1
- 230000004438 eyesight Effects 0.000 abstract 1
- 230000004313 glare Effects 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 102000054055 human PRG4 Human genes 0.000 abstract 1
- 230000004297 night vision Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Marine Sciences & Fisheries (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pyrane Compounds (AREA)
- Prostheses (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562163753P | 2015-05-19 | 2015-05-19 | |
| PCT/US2016/033248 WO2016187414A1 (en) | 2015-05-19 | 2016-05-19 | Use of prg4 to improve dynamic visual acuity and higher order aberrations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1124538T1 true CY1124538T1 (el) | 2022-07-22 |
Family
ID=57320651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20211100858T CY1124538T1 (el) | 2015-05-19 | 2021-10-05 | Χρηση prg4 για τη βελτιωση της δυναμικης οπτικης οξυτητας και εκτροπων υψηλοτερης ταξης |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11666529B2 (https=) |
| EP (1) | EP3300482B1 (https=) |
| JP (2) | JP7291459B2 (https=) |
| CY (1) | CY1124538T1 (https=) |
| DK (1) | DK3300482T3 (https=) |
| ES (1) | ES2893304T3 (https=) |
| HR (1) | HRP20211589T1 (https=) |
| HU (1) | HUE056409T2 (https=) |
| LT (1) | LT3300482T (https=) |
| MA (1) | MA42148A (https=) |
| PL (1) | PL3300482T3 (https=) |
| PT (1) | PT3300482T (https=) |
| SI (1) | SI3300482T1 (https=) |
| WO (1) | WO2016187414A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015060935A1 (en) | 2013-10-22 | 2015-04-30 | Lubris, Llc | Control of rheological properties of mixed hyaluronate/lubricin solutions |
| AU2016211694B2 (en) | 2015-01-26 | 2021-11-11 | Lubris Llc | Use of PRG4 as an anti-inflammatory agent |
| MX2020013869A (es) * | 2018-06-21 | 2021-03-02 | Lubris Llc | Lubricina para uso en curacion de heridas referencia cruzada con solicitudes relacionadas. |
| JP7667569B2 (ja) * | 2019-01-15 | 2025-04-23 | コーネル ユニバーシティー | 組換えラブリシン、並びにそれを使用するための組成物及び方法 |
| KR20220145361A (ko) * | 2020-02-24 | 2022-10-28 | 노파르티스 아게 | 재조합적으로 생성된 폴리펩타이드의 정제 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6433142B1 (en) | 1989-08-08 | 2002-08-13 | Genetics Institute, Llc | Megakaryocyte stimulating factors |
| US6743774B1 (en) | 1999-04-23 | 2004-06-01 | Rhode Island Hospital | Tribonectins |
| US6960562B2 (en) | 1999-04-23 | 2005-11-01 | Rhode Island Hospital, A Lifespan Partner | Tribonectin polypeptides and uses thereof |
| US7001881B1 (en) | 1999-04-23 | 2006-02-21 | Rhode Island Hospital | Tribonectins |
| US7415381B2 (en) | 2003-01-09 | 2008-08-19 | Rhode Island Hospital, A Lifespan Partner | Joint friction sensing |
| US20060240037A1 (en) | 2003-06-04 | 2006-10-26 | Edward Fey | Methods and compositions for the treatment and prevention of degenerative joint disorders |
| US20090155200A1 (en) | 2004-04-20 | 2009-06-18 | Jay Gregory D | Methods of promoting cartilage healing or cartilage integration |
| JP2008507553A (ja) | 2004-07-23 | 2008-03-13 | ミューコサル セラピューティクス リミテッド ライアビリディ カンパニー | 粘性補給のための組成物および方法 |
| EP1827478A4 (en) | 2004-12-03 | 2009-08-05 | Mucosal Therapeutics Llc | METHODS OF TREATING JOINED OR SICK JOINTS |
| US20070111327A1 (en) | 2005-05-05 | 2007-05-17 | Jay Gregory D | Methods of detecting lubricin |
| US8144631B2 (en) | 2006-12-13 | 2012-03-27 | Cisco Technology, Inc. | Interconnecting IP video endpoints with reduced H.320 call setup time |
| WO2008143816A1 (en) | 2007-05-15 | 2008-11-27 | Mucosal Therapeutics | Compositions and methods for reducing friction between the surface of tendons or other soft tissues |
| US20090068247A1 (en) | 2007-09-12 | 2009-03-12 | Mucosal Therapeutics | Biocompatible devices coated with a tribonectin and methods for their production |
| US20090104148A1 (en) | 2007-09-18 | 2009-04-23 | Jay Gregory D | Treatment and prevention of joint disease |
| US8506944B2 (en) | 2008-05-07 | 2013-08-13 | The Regents Of The University Of California | Replenishment and enrichment of ocular surface lubrication |
| HUE024146T2 (en) | 2008-05-07 | 2016-02-29 | Univ California | Medical filling and enrichment of eye surface lubrication |
| US8980840B2 (en) | 2009-01-13 | 2015-03-17 | Schepens Eye Research Institute | Therapeutic modulation of vaginal epithelium boundary lubrication |
| JP2012527485A (ja) | 2009-05-22 | 2012-11-08 | ルブリス，エルエルシー． | Ｐｒｇ４及びその治療調節作用の応用及び使用 |
| ES2634505T3 (es) | 2009-08-13 | 2017-09-28 | Lubris Llc | Tratamiento de PRG4 para la cistitis intersticial |
| WO2011091000A2 (en) | 2010-01-19 | 2011-07-28 | Singularis, Inc. | Oral care compositions and methods |
| US8480227B2 (en) | 2010-07-30 | 2013-07-09 | Novartis Ag | Silicone hydrogel lenses with water-rich surfaces |
| US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
| US20130116186A1 (en) | 2011-10-04 | 2013-05-09 | Rhode Island Hospital, A Lifespan Partner | Lubricin injections to maintain cartilage health |
| WO2015060935A1 (en) | 2013-10-22 | 2015-04-30 | Lubris, Llc | Control of rheological properties of mixed hyaluronate/lubricin solutions |
| AU2014354859B2 (en) | 2013-11-26 | 2020-04-09 | Lubris Llc | Compositions and methods for inhibiting intercellular interactions |
| AU2016211694B2 (en) | 2015-01-26 | 2021-11-11 | Lubris Llc | Use of PRG4 as an anti-inflammatory agent |
| US20180161393A1 (en) | 2015-01-26 | 2018-06-14 | Lubris Llc | Prg4 for treating gout and its symptoms |
| US20170312335A1 (en) | 2015-12-30 | 2017-11-02 | Lubris Llc | Topical use of prg4 for treatment of allergy and symptoms of inflammation |
-
2016
- 2016-05-19 WO PCT/US2016/033248 patent/WO2016187414A1/en not_active Ceased
- 2016-05-19 HR HRP20211589TT patent/HRP20211589T1/hr unknown
- 2016-05-19 ES ES16797292T patent/ES2893304T3/es active Active
- 2016-05-19 DK DK16797292.6T patent/DK3300482T3/da active
- 2016-05-19 PT PT16797292T patent/PT3300482T/pt unknown
- 2016-05-19 HU HUE16797292A patent/HUE056409T2/hu unknown
- 2016-05-19 PL PL16797292T patent/PL3300482T3/pl unknown
- 2016-05-19 MA MA042148A patent/MA42148A/fr unknown
- 2016-05-19 EP EP16797292.6A patent/EP3300482B1/en active Active
- 2016-05-19 US US15/574,712 patent/US11666529B2/en active Active
- 2016-05-19 LT LTEPPCT/US2016/033248T patent/LT3300482T/lt unknown
- 2016-05-19 SI SI201631361T patent/SI3300482T1/sl unknown
- 2016-05-19 JP JP2017559312A patent/JP7291459B2/ja active Active
-
2021
- 2021-06-16 JP JP2021099827A patent/JP2021167318A/ja active Pending
- 2021-10-05 CY CY20211100858T patent/CY1124538T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016187414A1 (en) | 2016-11-24 |
| JP7291459B2 (ja) | 2023-06-15 |
| JP2018515534A (ja) | 2018-06-14 |
| LT3300482T (lt) | 2021-10-25 |
| HUE056409T2 (hu) | 2022-02-28 |
| ES2893304T3 (es) | 2022-02-08 |
| HRP20211589T1 (hr) | 2022-01-07 |
| MA42148A (fr) | 2018-04-04 |
| EP3300482A1 (en) | 2018-04-04 |
| US11666529B2 (en) | 2023-06-06 |
| JP2021167318A (ja) | 2021-10-21 |
| EP3300482A4 (en) | 2019-02-13 |
| EP3300482B1 (en) | 2021-07-14 |
| US20180140546A1 (en) | 2018-05-24 |
| SI3300482T1 (sl) | 2021-11-30 |
| PT3300482T (pt) | 2021-10-15 |
| PL3300482T3 (pl) | 2022-01-03 |
| DK3300482T3 (da) | 2021-10-18 |
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