CY1123929T1 - Μεθοδος για παρασκευη πηκτωματος φωσφορικου αργιλιου για εφαρμογη σε φαρμακοτεχνικες μορφες εμβολιων - Google Patents
Μεθοδος για παρασκευη πηκτωματος φωσφορικου αργιλιου για εφαρμογη σε φαρμακοτεχνικες μορφες εμβολιωνInfo
- Publication number
- CY1123929T1 CY1123929T1 CY20211100192T CY211100192T CY1123929T1 CY 1123929 T1 CY1123929 T1 CY 1123929T1 CY 20211100192 T CY20211100192 T CY 20211100192T CY 211100192 T CY211100192 T CY 211100192T CY 1123929 T1 CY1123929 T1 CY 1123929T1
- Authority
- CY
- Cyprus
- Prior art keywords
- aluminum phosphate
- phosphate gel
- preparation
- pharmaceutical forms
- vaccine pharmaceutical
- Prior art date
Links
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 1
- 239000002244 precipitate Substances 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B25/00—Phosphorus; Compounds thereof
- C01B25/16—Oxyacids of phosphorus; Salts thereof
- C01B25/26—Phosphates
- C01B25/36—Aluminium phosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2004/00—Particle morphology
- C01P2004/51—Particles with a specific particle size distribution
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2004/00—Particle morphology
- C01P2004/60—Particles characterised by their size
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2004/00—Particle morphology
- C01P2004/60—Particles characterised by their size
- C01P2004/61—Micrometer sized, i.e. from 1-100 micrometer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με μια βελτιωμένη διεργασία για παραγωγή πηκτώματος φωσφορικού Αργιλίου (AlPhos) όπου τα διαλύματα του άλατος αργιλίου και αλκαλικού φωσφορικού άλατος προστίθενται σε ύδωρ από διατήρηση του pΗ υπό ανάδευση για λήψη του ιζήματος, ακολουθούμενα από αποστείρωση του εν λόγω ιζήματος και τελικά λήψη του πηκτώματος φωσφορικού Αργιλίου.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2963CH2015 | 2015-06-12 | ||
| PCT/IN2016/000151 WO2016199162A2 (en) | 2015-06-12 | 2016-06-13 | Method for preparation of aluminium phosphate gel for application in vaccine formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1123929T1 true CY1123929T1 (el) | 2022-05-27 |
Family
ID=56740279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20211100192T CY1123929T1 (el) | 2015-06-12 | 2021-03-05 | Μεθοδος για παρασκευη πηκτωματος φωσφορικου αργιλιου για εφαρμογη σε φαρμακοτεχνικες μορφες εμβολιων |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10744200B2 (el) |
| EP (1) | EP3307315B1 (el) |
| JP (1) | JP6989389B2 (el) |
| CN (1) | CN107921119B (el) |
| AU (1) | AU2016276656B2 (el) |
| BR (1) | BR112017026816A2 (el) |
| CA (1) | CA2989187A1 (el) |
| CY (1) | CY1123929T1 (el) |
| DK (1) | DK3307315T3 (el) |
| EA (2) | EA202092048A1 (el) |
| ES (1) | ES2862379T3 (el) |
| HR (1) | HRP20210421T1 (el) |
| HU (1) | HUE053003T2 (el) |
| LT (1) | LT3307315T (el) |
| MX (1) | MX2017016078A (el) |
| PL (1) | PL3307315T3 (el) |
| PT (1) | PT3307315T (el) |
| RS (1) | RS61514B1 (el) |
| SA (1) | SA517390507B1 (el) |
| SI (1) | SI3307315T1 (el) |
| SM (1) | SMT202100130T1 (el) |
| WO (1) | WO2016199162A2 (el) |
| ZA (1) | ZA201708592B (el) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114796478A (zh) * | 2022-05-24 | 2022-07-29 | 华裕(无锡)制药有限公司 | 一种磷酸铝佐剂的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB777018A (en) * | 1955-05-02 | 1957-06-12 | Parke Davis & Co | Poliomyelitis vaccine products and methods for preparing the same |
| NL255524A (el) * | 1959-09-03 | |||
| JPS5020560B1 (el) * | 1969-12-19 | 1975-07-16 | ||
| DE2152228C3 (de) | 1971-10-20 | 1980-03-27 | Giulini Chemie Gmbh, 6700 Ludwigshafen | Verfahren zur Herstellung eines therapeutisch wirksamen Aluminiumphosphat-Gels |
| SU481539A1 (ru) | 1972-03-13 | 1975-08-25 | Ордена Трудового Красного Знамени Институт Физической Химии Им. Л.В.Писаржевского Ан Украинской Сср | Способ получени пористого алюмофосфата |
| SU559895A1 (ru) | 1974-11-06 | 1977-05-30 | Белорусский Технологический Институт Имени С.М.Кирова | Способ получени фосфата алюмини |
| SU550340A1 (ru) | 1975-02-17 | 1977-03-15 | Белорусский технологический институт им. С.М.Кирова | Способ получени гелеобразного фосфата алюмини с развитой удельной поверхностью |
| RU2149138C1 (ru) | 1998-06-08 | 2000-05-20 | Государственное унитарное предприятие "Иммунопрепарат" | Способ получения геля фосфата алюминия |
| US8540955B2 (en) * | 2007-07-10 | 2013-09-24 | Wyeth Llc | Process for producing aluminum phosphate |
| WO2009136233A1 (en) | 2008-05-08 | 2009-11-12 | Serum Institute Of India Ltd. | Aluminium phosphate nanoparticles |
| US9796788B2 (en) * | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| CN102188701A (zh) * | 2010-03-12 | 2011-09-21 | 上海泽润生物科技有限公司 | 一种磷酸铝佐剂及其制备方法 |
| IN2014CN03391A (el) | 2011-11-23 | 2015-07-03 | Merck Sharp & Dohme |
-
2016
- 2016-06-13 US US15/772,777 patent/US10744200B2/en active Active
- 2016-06-13 SI SI201631122T patent/SI3307315T1/sl unknown
- 2016-06-13 BR BR112017026816A patent/BR112017026816A2/pt active Search and Examination
- 2016-06-13 PL PL16753991T patent/PL3307315T3/pl unknown
- 2016-06-13 DK DK16753991.5T patent/DK3307315T3/da active
- 2016-06-13 RS RS20210250A patent/RS61514B1/sr unknown
- 2016-06-13 SM SM20210130T patent/SMT202100130T1/it unknown
- 2016-06-13 AU AU2016276656A patent/AU2016276656B2/en active Active
- 2016-06-13 EA EA202092048A patent/EA202092048A1/ru unknown
- 2016-06-13 JP JP2017564347A patent/JP6989389B2/ja active Active
- 2016-06-13 CA CA2989187A patent/CA2989187A1/en active Pending
- 2016-06-13 WO PCT/IN2016/000151 patent/WO2016199162A2/en active Application Filing
- 2016-06-13 LT LTEP16753991.5T patent/LT3307315T/lt unknown
- 2016-06-13 PT PT167539915T patent/PT3307315T/pt unknown
- 2016-06-13 ES ES16753991T patent/ES2862379T3/es active Active
- 2016-06-13 EP EP16753991.5A patent/EP3307315B1/en active Active
- 2016-06-13 CN CN201680041148.7A patent/CN107921119B/zh active Active
- 2016-06-13 HU HUE16753991A patent/HUE053003T2/hu unknown
- 2016-06-13 MX MX2017016078A patent/MX2017016078A/es unknown
- 2016-06-13 EA EA201890430A patent/EA036560B1/ru unknown
-
2017
- 2017-12-10 SA SA517390507A patent/SA517390507B1/ar unknown
- 2017-12-18 ZA ZA2017/08592A patent/ZA201708592B/en unknown
-
2021
- 2021-03-05 CY CY20211100192T patent/CY1123929T1/el unknown
- 2021-03-12 HR HRP20210421TT patent/HRP20210421T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN107921119B (zh) | 2021-10-08 |
| JP2018518447A (ja) | 2018-07-12 |
| AU2016276656A1 (en) | 2018-01-04 |
| WO2016199162A3 (en) | 2017-01-19 |
| HUE053003T2 (hu) | 2021-06-28 |
| EA202092048A1 (ru) | 2020-11-09 |
| AU2016276656B2 (en) | 2022-03-03 |
| SMT202100130T1 (it) | 2021-05-07 |
| RS61514B1 (sr) | 2021-03-31 |
| LT3307315T (lt) | 2021-04-12 |
| CN107921119A (zh) | 2018-04-17 |
| PT3307315T (pt) | 2021-03-17 |
| BR112017026816A2 (pt) | 2018-08-14 |
| SI3307315T1 (sl) | 2021-05-31 |
| EP3307315B1 (en) | 2021-01-27 |
| EP3307315A2 (en) | 2018-04-18 |
| CA2989187A1 (en) | 2016-12-15 |
| PL3307315T3 (pl) | 2021-06-28 |
| EA036560B1 (ru) | 2020-11-23 |
| ZA201708592B (en) | 2022-03-30 |
| MX2017016078A (es) | 2018-05-15 |
| ES2862379T3 (es) | 2021-10-07 |
| US20190240322A1 (en) | 2019-08-08 |
| JP6989389B2 (ja) | 2022-01-05 |
| US10744200B2 (en) | 2020-08-18 |
| EA201890430A1 (ru) | 2018-06-29 |
| DK3307315T3 (da) | 2021-03-15 |
| WO2016199162A2 (en) | 2016-12-15 |
| HRP20210421T1 (hr) | 2021-04-30 |
| SA517390507B1 (ar) | 2021-04-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1125084T1 (el) | Εμβολια νουκλεϊκου οξεος | |
| CY1124845T1 (el) | Μεθοδοι παροχης μονοκλωνου rna | |
| CY1120969T1 (el) | Παραγωγα κινοξαλινης χρησιμα ως τροποποιητες fgfr κινασης | |
| CY1121736T1 (el) | Άλατα aramchol | |
| CY1119676T1 (el) | Συνθεσεις και μεθοδοι για τη θεραπεια του καρκινου | |
| EA201990293A1 (ru) | Мультиспецифичные антитела против cd40 и cd137 | |
| BR112017024384A2 (pt) | bactérias modificadas para reduzir hiperfenilalaninemia | |
| CY1123963T1 (el) | Καινοτομα πολυμερικα προφαρμακα hgh | |
| CY1125033T1 (el) | Σκευασμα μεθοτρεξατης | |
| CY1118900T1 (el) | Δικυκλικως υποκατεστημενες ουρακιλες και η χρηση αυτων | |
| CY1119957T1 (el) | Θεραπεια νοσηματων με τη χρηση ανοχογονου φαρμακευτικου παρασκευασματος | |
| EA201692473A1 (ru) | Способы получения замещенных нуклеотидных аналогов | |
| EA201892802A1 (ru) | Производные аденозина для применения при лечении рака | |
| EA201890442A1 (ru) | Получение фоторецепторов для лечения заболеваний сетчатки | |
| CY1121859T1 (el) | Μεθοδος παρασκευης αναστολεων συνθασης γλυκοζυλοκεραμιδης | |
| EA201692288A1 (ru) | Способ получения фосфорсодержащих циангидринов | |
| CY1124529T1 (el) | Ενωσεις λευκοχρυσου λειτουργικοποιημενες με μονομηλεινιμιδιο για θεραπεια καρκινου | |
| CY1124420T1 (el) | Μεθοδος για την παρασκευη ενος προϊοντος υδατανθρακα και/ή πρωτεϊνης | |
| EA201891342A1 (ru) | Изоиндольные соединения | |
| CY1120185T1 (el) | Υποκατεστημενα πυριδινικα παραγωγα χρησιμα ως αναστολεις c-fms κινασης | |
| CY1122728T1 (el) | Αντισωματα εναντι hpa-1a | |
| CY1124492T1 (el) | 7-υποκατεστημενα 1-αρυλο-ναφθυριδιν-3-καρβοξαμιδια και η χρηση αυτων | |
| CY1123877T1 (el) | Μορφες στερεας καταστασης αλατων νιλοτινιμπης | |
| EA201692518A3 (ru) | Способы улучшения производительности миокарда у пациентов после операции фонтена с применением композиций уденафила | |
| CY1124164T1 (el) | Καινοτομος παρασκευη και κρυσταλλωση της ιοσιμενολης |