CY1119240T1 - Εξωθηση τηγματος πολλαπλων σφαιρικων σωματιδιων - Google Patents
Εξωθηση τηγματος πολλαπλων σφαιρικων σωματιδιωνInfo
- Publication number
- CY1119240T1 CY1119240T1 CY20171100796T CY171100796T CY1119240T1 CY 1119240 T1 CY1119240 T1 CY 1119240T1 CY 20171100796 T CY20171100796 T CY 20171100796T CY 171100796 T CY171100796 T CY 171100796T CY 1119240 T1 CY1119240 T1 CY 1119240T1
- Authority
- CY
- Cyprus
- Prior art keywords
- extraction
- sphere particles
- nozzles
- filament
- multiple sphere
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Η εφεύρεση αφορά σε μία μέθοδο για παρασκευή φαρμακευτικού εξωθήματος ελεγχόμενης απελευθέρωσης χρησιμοποιώντας εξωθητή τήγματος, όπου ο εξωθητής τήγματος περιλαμβάνει κεφαλή φιλιέρας που υποστηρίζει πλάκα φιλιέρας στην οποία είναι τοποθετημένα στόμια και έναν κόφτη γειτονικό προς την κεφαλή φιλιέρας και όπου ο κόφτης κόβει το εξωθούμενο μείγμα καθώς αυτό αναφύεται υπό πίεση και εισέτι τετηγμένο ή μαλακυνθέν από τα στόμια της πλάκας φιλιέρας.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0403098.7A GB0403098D0 (en) | 2004-02-12 | 2004-02-12 | Extrusion |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1119240T1 true CY1119240T1 (el) | 2018-02-14 |
Family
ID=32011772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20171100796T CY1119240T1 (el) | 2004-02-12 | 2017-07-25 | Εξωθηση τηγματος πολλαπλων σφαιρικων σωματιδιων |
Country Status (11)
Country | Link |
---|---|
US (2) | US20050191352A1 (el) |
EP (1) | EP1586311B1 (el) |
CY (1) | CY1119240T1 (el) |
DK (1) | DK1586311T3 (el) |
ES (1) | ES2628960T3 (el) |
GB (1) | GB0403098D0 (el) |
HU (1) | HUE035445T2 (el) |
LT (1) | LT1586311T (el) |
PL (1) | PL1586311T3 (el) |
PT (1) | PT1586311T (el) |
SI (1) | SI1586311T1 (el) |
Families Citing this family (32)
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US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
TWI350762B (en) * | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US7807715B2 (en) * | 2006-06-09 | 2010-10-05 | Ucb Pharma Gmbh | Pharmaceutical compositions comprising fesoterodine |
WO2008100865A1 (en) | 2007-02-13 | 2008-08-21 | Nye Paul H | A personal affector machine |
DE102007009242A1 (de) * | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit magensaftresistenter Wirkstoff-Matix |
DE102007009243A1 (de) | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit einer Wirkstoff-Matrix und einem Polymerüberzug, sowie ein Verfahren zur Herstellung der Pellets |
CA2711473C (en) * | 2008-01-10 | 2016-01-26 | Evonik Roehm Gmbh | Coated pharmaceutical or nutraceutical preparation with enhanced active substance release in the colon |
WO2009086942A1 (en) * | 2008-01-10 | 2009-07-16 | Evonik Röhm Gmbh | Coated pharmaceutical or nutraceutical preparation with accelerated controlled active substance release |
BRPI0906467C1 (pt) | 2008-01-25 | 2021-05-25 | Gruenenthal Gmbh | forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada |
WO2009134848A1 (en) * | 2008-04-30 | 2009-11-05 | Novartis Ag | Continuous process for making pharmaceutical compositions |
GB0909680D0 (en) | 2009-06-05 | 2009-07-22 | Euro Celtique Sa | Dosage form |
PE20121067A1 (es) | 2009-07-22 | 2012-09-05 | Gruenenthal Chemie | Forma de dosificacion de liberacion controlada extruida por fusion en caliente |
WO2011009604A1 (en) | 2009-07-22 | 2011-01-27 | Grünenthal GmbH | Oxidation-stabilized tamper-resistant dosage form |
US9232670B2 (en) * | 2010-02-02 | 2016-01-05 | Apple Inc. | Protection and assembly of outer glass surfaces of an electronic device housing |
WO2012028319A1 (en) | 2010-09-02 | 2012-03-08 | Grünenthal GmbH | Tamper resistant dosage form comprising inorganic salt |
GB201020895D0 (en) * | 2010-12-09 | 2011-01-26 | Euro Celtique Sa | Dosage form |
KR20140053158A (ko) | 2011-07-29 | 2014-05-07 | 그뤼넨탈 게엠베하 | 즉시 약물 방출을 제공하는 탬퍼-저항성 정제 |
AR087360A1 (es) | 2011-07-29 | 2014-03-19 | Gruenenthal Gmbh | Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato |
JP6282261B2 (ja) * | 2012-04-18 | 2018-02-21 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 不正使用防止および過量放出防止医薬剤形 |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
EP3003279A1 (en) | 2013-05-29 | 2016-04-13 | Grünenthal GmbH | Tamper-resistant dosage form containing one or more particles |
AU2014289187B2 (en) | 2013-07-12 | 2019-07-11 | Grunenthal Gmbh | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
MX371372B (es) | 2013-11-26 | 2020-01-28 | Gruenenthal Gmbh | Preparacion de una composicion farmaceutica en polvo por medio de criomolienda. |
CA2947786A1 (en) | 2014-05-12 | 2015-11-19 | Grunenthal Gmbh | Tamper resistant immediate release capsule formulation comprising tapentadol |
WO2015181059A1 (en) | 2014-05-26 | 2015-12-03 | Grünenthal GmbH | Multiparticles safeguarded against ethanolic dose-dumping |
JP2018517676A (ja) | 2015-04-24 | 2018-07-05 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 即時放出および溶媒抽出に対する耐性を有する改変防止製剤 |
WO2017042325A1 (en) | 2015-09-10 | 2017-03-16 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
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GB1603640A (en) * | 1977-07-20 | 1981-11-25 | Gist Brocades Nv | Enzyme particles |
US4331623A (en) * | 1978-09-22 | 1982-05-25 | El Paso Polyolefins Company | Polymer flow through die |
US4327050A (en) * | 1980-09-22 | 1982-04-27 | Phillips Petroleum Company | Extrusion and pelleting apparatus and method |
JPS5996187A (ja) * | 1982-11-24 | 1984-06-02 | Nippon Steel Corp | ピツチペレツトの製造方法 |
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CN1165291C (zh) * | 1996-05-20 | 2004-09-08 | 詹森药业有限公司 | 具有改进的生物利用度的抗真菌组合物 |
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KR20090029856A (ko) * | 2005-01-28 | 2009-03-23 | 유로-셀띠끄 소시에떼 아노님 | 알코올 저항성 제형 |
-
2004
- 2004-02-12 GB GBGB0403098.7A patent/GB0403098D0/en not_active Ceased
-
2005
- 2005-02-11 EP EP05075341.7A patent/EP1586311B1/en not_active Revoked
- 2005-02-11 SI SI200532160T patent/SI1586311T1/sl unknown
- 2005-02-11 US US11/056,035 patent/US20050191352A1/en not_active Abandoned
- 2005-02-11 ES ES05075341.7T patent/ES2628960T3/es active Active
- 2005-02-11 LT LTEP05075341.7T patent/LT1586311T/lt unknown
- 2005-02-11 PL PL05075341T patent/PL1586311T3/pl unknown
- 2005-02-11 PT PT50753417T patent/PT1586311T/pt unknown
- 2005-02-11 DK DK05075341.7T patent/DK1586311T3/en active
- 2005-02-11 HU HUE05075341A patent/HUE035445T2/en unknown
-
2008
- 2008-09-30 US US12/241,650 patent/US9603802B2/en active Active
-
2017
- 2017-07-25 CY CY20171100796T patent/CY1119240T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HUE035445T2 (en) | 2018-05-28 |
US20090029170A1 (en) | 2009-01-29 |
ES2628960T3 (es) | 2017-08-04 |
EP1586311A2 (en) | 2005-10-19 |
DK1586311T3 (en) | 2017-08-14 |
EP1586311A3 (en) | 2011-04-06 |
SI1586311T1 (sl) | 2017-09-29 |
PL1586311T3 (pl) | 2017-10-31 |
GB0403098D0 (en) | 2004-03-17 |
US9603802B2 (en) | 2017-03-28 |
PT1586311T (pt) | 2017-07-13 |
US20050191352A1 (en) | 2005-09-01 |
LT1586311T (lt) | 2017-08-25 |
EP1586311B1 (en) | 2017-05-03 |
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