CY1118727T1 - Φαρμακευτικη συνθεση με φωσφολιπιδιο - Google Patents

Φαρμακευτικη συνθεση με φωσφολιπιδιο

Info

Publication number
CY1118727T1
CY1118727T1 CY20161101165T CY161101165T CY1118727T1 CY 1118727 T1 CY1118727 T1 CY 1118727T1 CY 20161101165 T CY20161101165 T CY 20161101165T CY 161101165 T CY161101165 T CY 161101165T CY 1118727 T1 CY1118727 T1 CY 1118727T1
Authority
CY
Cyprus
Prior art keywords
phospholipid
pharmaceutical composition
composition
concentration
active ingredient
Prior art date
Application number
CY20161101165T
Other languages
English (en)
Inventor
Bernd G Seigfried
Original Assignee
Mika Pharma Gesellschaft Für Die Entwicklung Und Vermarktung Pharmazeutischer Produkte Mbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mika Pharma Gesellschaft Für Die Entwicklung Und Vermarktung Pharmazeutischer Produkte Mbh filed Critical Mika Pharma Gesellschaft Für Die Entwicklung Und Vermarktung Pharmazeutischer Produkte Mbh
Publication of CY1118727T1 publication Critical patent/CY1118727T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Περιγράφεται μια φαρμακευτική σύνθεση για την εφαρμογή στον άνθρωπο και στα ζώα, με τουλάχιστον ένα συστημικής ή/και τοπικής δράσης, τοπικώς εφαρμοζόμενο δραστικό συστατικό και με τουλάχιστον ένα φωσφολιπίδιο το οποίο βελτιώνει τη μεταφορά του δραστικού συστατικού μέσω της κυτταρικής μεμβράνης, το οποίο περιέχει φωσφατιδυλοχολίνη σε μια συγκέντρωση τουλάχιστον 60 % κ.β., η οποία αναφέρεται στο φωσφολιπίδιο. Η σύνθεση έχει μια τέτοια υγρή συνοχή ώστε είναι σε θέση να ψεκάζεται ως σταγονίδια ή ως αφρός, όπου η σύνθεση περιέχει ένα τέτοιο φωσφολιπίδιο το οποίο επιπροσθέτως αποτελείται, εκτός από την τουλάχιστον 60 % κ.β. φωσφατιδυλοχολίνη, από έλαιο σε μια συγκέντρωση 7,5 % κ.β. κατά το μέγιστο.
CY20161101165T 2012-05-15 2016-11-14 Φαρμακευτικη συνθεση με φωσφολιπιδιο CY1118727T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012009575 2012-05-15
DE102013004199A DE102013004199A1 (de) 2012-05-15 2013-03-12 Pharmazeutische Zusammensetzung

Publications (1)

Publication Number Publication Date
CY1118727T1 true CY1118727T1 (el) 2017-07-12

Family

ID=47901750

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161101165T CY1118727T1 (el) 2012-05-15 2016-11-14 Φαρμακευτικη συνθεση με φωσφολιπιδιο

Country Status (18)

Country Link
EP (1) EP2638894B1 (el)
JP (1) JP2013237669A (el)
BR (1) BR102013011801B1 (el)
CA (1) CA2815477C (el)
CY (1) CY1118727T1 (el)
DE (1) DE102013004199A1 (el)
DK (1) DK2638894T3 (el)
ES (1) ES2606031T3 (el)
HR (1) HRP20161318T1 (el)
HU (1) HUE029793T2 (el)
LT (1) LT2638894T (el)
MX (1) MX342069B (el)
PL (1) PL2638894T3 (el)
PT (1) PT2638894T (el)
RS (1) RS55291B1 (el)
RU (1) RU2659943C2 (el)
SI (1) SI2638894T1 (el)
SM (1) SMT201600419B (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10596117B1 (en) 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds
US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
US11007161B1 (en) 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0521398T3 (da) * 1991-07-05 1999-07-05 Rhone Poulenc Rorer Gmbh Phospholipidsammensætning
US6113921A (en) * 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
DE4313402A1 (de) * 1993-04-23 1994-10-27 Hexal Pharma Gmbh Transdermale Wirkstoffzubereitung
AU7977294A (en) * 1993-10-07 1995-05-01 Odontex, Inc. Absorption enhancers for topical pharmaceutical formulations
ES2180599T3 (es) 1994-09-30 2003-02-16 Mika Pharma Ges Fur Die Entwic Composicion farmaceutica.
JP2008514606A (ja) * 2004-09-24 2008-05-08 リポ ケミカルズ インコーポレイテッド 局所適用化合物のためのデリバリーシステム
CA2752849C (en) * 2009-07-24 2014-07-08 Bernd G. Seigfried Liquid compositions capable of foaming and including active agents, and methods for making or developing same

Also Published As

Publication number Publication date
DE102013004199A1 (de) 2013-11-21
CA2815477C (en) 2017-05-02
PL2638894T3 (pl) 2017-02-28
PT2638894T (pt) 2016-12-13
HUE029793T2 (en) 2017-04-28
BR102013011801B1 (pt) 2022-08-09
MX2013005306A (es) 2013-11-26
SI2638894T1 (sl) 2017-01-31
SMT201600419B (it) 2017-01-10
JP2013237669A (ja) 2013-11-28
EP2638894A1 (de) 2013-09-18
DK2638894T3 (en) 2016-10-17
RS55291B1 (sr) 2017-03-31
EP2638894B1 (de) 2016-09-14
HRP20161318T1 (hr) 2016-12-16
RU2013121269A (ru) 2014-11-20
LT2638894T (lt) 2017-02-10
BR102013011801A2 (pt) 2015-11-10
MX342069B (es) 2016-09-13
ES2606031T3 (es) 2017-03-17
CA2815477A1 (en) 2013-11-15
RU2659943C2 (ru) 2018-07-04

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