CY1118727T1 - Φαρμακευτικη συνθεση με φωσφολιπιδιο - Google Patents
Φαρμακευτικη συνθεση με φωσφολιπιδιοInfo
- Publication number
- CY1118727T1 CY1118727T1 CY20161101165T CY161101165T CY1118727T1 CY 1118727 T1 CY1118727 T1 CY 1118727T1 CY 20161101165 T CY20161101165 T CY 20161101165T CY 161101165 T CY161101165 T CY 161101165T CY 1118727 T1 CY1118727 T1 CY 1118727T1
- Authority
- CY
- Cyprus
- Prior art keywords
- phospholipid
- pharmaceutical composition
- composition
- concentration
- active ingredient
- Prior art date
Links
- 150000003904 phospholipids Chemical class 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 239000006260 foam Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Περιγράφεται μια φαρμακευτική σύνθεση για την εφαρμογή στον άνθρωπο και στα ζώα, με τουλάχιστον ένα συστημικής ή/και τοπικής δράσης, τοπικώς εφαρμοζόμενο δραστικό συστατικό και με τουλάχιστον ένα φωσφολιπίδιο το οποίο βελτιώνει τη μεταφορά του δραστικού συστατικού μέσω της κυτταρικής μεμβράνης, το οποίο περιέχει φωσφατιδυλοχολίνη σε μια συγκέντρωση τουλάχιστον 60 % κ.β., η οποία αναφέρεται στο φωσφολιπίδιο. Η σύνθεση έχει μια τέτοια υγρή συνοχή ώστε είναι σε θέση να ψεκάζεται ως σταγονίδια ή ως αφρός, όπου η σύνθεση περιέχει ένα τέτοιο φωσφολιπίδιο το οποίο επιπροσθέτως αποτελείται, εκτός από την τουλάχιστον 60 % κ.β. φωσφατιδυλοχολίνη, από έλαιο σε μια συγκέντρωση 7,5 % κ.β. κατά το μέγιστο.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102012009575 | 2012-05-15 | ||
DE102013004199A DE102013004199A1 (de) | 2012-05-15 | 2013-03-12 | Pharmazeutische Zusammensetzung |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1118727T1 true CY1118727T1 (el) | 2017-07-12 |
Family
ID=47901750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20161101165T CY1118727T1 (el) | 2012-05-15 | 2016-11-14 | Φαρμακευτικη συνθεση με φωσφολιπιδιο |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP2638894B1 (el) |
JP (1) | JP2013237669A (el) |
BR (1) | BR102013011801B1 (el) |
CA (1) | CA2815477C (el) |
CY (1) | CY1118727T1 (el) |
DE (1) | DE102013004199A1 (el) |
DK (1) | DK2638894T3 (el) |
ES (1) | ES2606031T3 (el) |
HR (1) | HRP20161318T1 (el) |
HU (1) | HUE029793T2 (el) |
LT (1) | LT2638894T (el) |
MX (1) | MX342069B (el) |
PL (1) | PL2638894T3 (el) |
PT (1) | PT2638894T (el) |
RS (1) | RS55291B1 (el) |
RU (1) | RU2659943C2 (el) |
SI (1) | SI2638894T1 (el) |
SM (1) | SMT201600419B (el) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10596117B1 (en) | 2014-12-31 | 2020-03-24 | Eric Morrison | Lipoleosomes as carriers for aromatic amide anesthetic compounds |
US10561627B2 (en) | 2014-12-31 | 2020-02-18 | Eric Morrison | Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films |
US11007161B1 (en) | 2014-12-31 | 2021-05-18 | Eric Morrison | Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0521398T3 (da) * | 1991-07-05 | 1999-07-05 | Rhone Poulenc Rorer Gmbh | Phospholipidsammensætning |
US6113921A (en) * | 1993-03-23 | 2000-09-05 | Pharmos Corp. | Topical and transdermal delivery system utilizing submicron oil spheres |
DE4313402A1 (de) * | 1993-04-23 | 1994-10-27 | Hexal Pharma Gmbh | Transdermale Wirkstoffzubereitung |
AU7977294A (en) * | 1993-10-07 | 1995-05-01 | Odontex, Inc. | Absorption enhancers for topical pharmaceutical formulations |
ES2180599T3 (es) | 1994-09-30 | 2003-02-16 | Mika Pharma Ges Fur Die Entwic | Composicion farmaceutica. |
JP2008514606A (ja) * | 2004-09-24 | 2008-05-08 | リポ ケミカルズ インコーポレイテッド | 局所適用化合物のためのデリバリーシステム |
CA2752849C (en) * | 2009-07-24 | 2014-07-08 | Bernd G. Seigfried | Liquid compositions capable of foaming and including active agents, and methods for making or developing same |
-
2013
- 2013-03-12 DE DE102013004199A patent/DE102013004199A1/de not_active Ceased
- 2013-03-18 ES ES13001361.8T patent/ES2606031T3/es active Active
- 2013-03-18 RS RS20160854A patent/RS55291B1/sr unknown
- 2013-03-18 LT LTEP13001361.8T patent/LT2638894T/lt unknown
- 2013-03-18 PT PT130013618T patent/PT2638894T/pt unknown
- 2013-03-18 EP EP13001361.8A patent/EP2638894B1/de active Active
- 2013-03-18 PL PL13001361T patent/PL2638894T3/pl unknown
- 2013-03-18 SI SI201330401A patent/SI2638894T1/sl unknown
- 2013-03-18 DK DK13001361.8T patent/DK2638894T3/en active
- 2013-03-18 HU HUE13001361A patent/HUE029793T2/en unknown
- 2013-05-08 JP JP2013098271A patent/JP2013237669A/ja active Pending
- 2013-05-09 CA CA2815477A patent/CA2815477C/en active Active
- 2013-05-10 MX MX2013005306A patent/MX342069B/es active IP Right Grant
- 2013-05-10 RU RU2013121269A patent/RU2659943C2/ru active
- 2013-05-13 BR BR102013011801-0A patent/BR102013011801B1/pt not_active IP Right Cessation
-
2016
- 2016-10-11 HR HRP20161318TT patent/HRP20161318T1/hr unknown
- 2016-11-14 CY CY20161101165T patent/CY1118727T1/el unknown
- 2016-11-18 SM SM201600419T patent/SMT201600419B/it unknown
Also Published As
Publication number | Publication date |
---|---|
DE102013004199A1 (de) | 2013-11-21 |
CA2815477C (en) | 2017-05-02 |
PL2638894T3 (pl) | 2017-02-28 |
PT2638894T (pt) | 2016-12-13 |
HUE029793T2 (en) | 2017-04-28 |
BR102013011801B1 (pt) | 2022-08-09 |
MX2013005306A (es) | 2013-11-26 |
SI2638894T1 (sl) | 2017-01-31 |
SMT201600419B (it) | 2017-01-10 |
JP2013237669A (ja) | 2013-11-28 |
EP2638894A1 (de) | 2013-09-18 |
DK2638894T3 (en) | 2016-10-17 |
RS55291B1 (sr) | 2017-03-31 |
EP2638894B1 (de) | 2016-09-14 |
HRP20161318T1 (hr) | 2016-12-16 |
RU2013121269A (ru) | 2014-11-20 |
LT2638894T (lt) | 2017-02-10 |
BR102013011801A2 (pt) | 2015-11-10 |
MX342069B (es) | 2016-09-13 |
ES2606031T3 (es) | 2017-03-17 |
CA2815477A1 (en) | 2013-11-15 |
RU2659943C2 (ru) | 2018-07-04 |
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