CY1113183T1 - Χρηση νατριουριτικου πεπτιδιου για θεραπεια καρδιακης ανεπαρκειας - Google Patents
Χρηση νατριουριτικου πεπτιδιου για θεραπεια καρδιακης ανεπαρκειαςInfo
- Publication number
- CY1113183T1 CY1113183T1 CY20121100652T CY121100652T CY1113183T1 CY 1113183 T1 CY1113183 T1 CY 1113183T1 CY 20121100652 T CY20121100652 T CY 20121100652T CY 121100652 T CY121100652 T CY 121100652T CY 1113183 T1 CY1113183 T1 CY 1113183T1
- Authority
- CY
- Cyprus
- Prior art keywords
- hours
- deficiency treatment
- heart deficiency
- natural purpose
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Η παρούσα αφορά στην χρήση ενός νατριουρητικού πεπτιδίου, όπως ουροδιλατίνης, για την θεραπεία ενός ασθενούς που υποφέρει από καρδιακή ανεπάρκεια, όπως οξεία καρδιακή ανεπάρκεια μετά νεφρωτικού συνδρόμου. Κατά προτίμηση, μια σύνθεση περιλαμβάνουσα αποτελεσματική ποσότητα ουροδιλατίνης χορηγείται ενδοφλεβίως στον ασθενή συνεχώς σε μια χρονική περίοδο τουλάχιστον 24 ωρών και μέχρι 120 ωρών, κατά προτίμηση 48 ωρών.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66978605P | 2005-04-07 | 2005-04-07 | |
US66975105P | 2005-04-08 | 2005-04-08 | |
US73258505P | 2005-11-01 | 2005-11-01 | |
EP06749753A EP1865976B1 (en) | 2005-04-07 | 2006-04-07 | Use of natriuretic peptide for treating heart failure |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1113183T1 true CY1113183T1 (el) | 2016-04-13 |
Family
ID=37087353
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100652T CY1113183T1 (el) | 2005-04-07 | 2012-07-23 | Χρηση νατριουριτικου πεπτιδιου για θεραπεια καρδιακης ανεπαρκειας |
Country Status (10)
Country | Link |
---|---|
US (5) | US7732406B2 (el) |
EP (2) | EP1865976B1 (el) |
CY (1) | CY1113183T1 (el) |
DK (2) | DK2510942T3 (el) |
ES (2) | ES2392892T3 (el) |
HU (1) | HUE026231T2 (el) |
PL (2) | PL2510942T3 (el) |
PT (2) | PT1865976E (el) |
SI (1) | SI2510942T1 (el) |
WO (1) | WO2006110743A1 (el) |
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EP1759001B1 (en) | 2004-04-21 | 2011-04-13 | Enobia Pharma Inc. | Bone delivery conjugates and method of using same to target proteins to bone |
EP1865976B1 (en) | 2005-04-07 | 2012-05-23 | Cardiopep Pharma GmbH | Use of natriuretic peptide for treating heart failure |
US7606617B2 (en) * | 2006-01-31 | 2009-10-20 | Cardiac Pacemakers, Inc. | Urinalysis for the early detection of and recovery from worsening heart failure |
US20080181903A1 (en) * | 2006-12-21 | 2008-07-31 | Pdl Biopharma, Inc. | Conjugate of natriuretic peptide and antibody constant region |
CN101541957B (zh) | 2007-07-20 | 2013-08-14 | 梅约医学教育与研究基金会 | 利尿钠多肽 |
EP2185183B1 (en) * | 2007-09-11 | 2016-03-16 | Cardiopep Pharma GmbH | Use of natriuretic peptides for treating angioedema syndromes |
EP2078530A1 (en) * | 2008-01-08 | 2009-07-15 | Pharis Biotec GmbH | Use of natriuretic peptides for treating angioedema syndromes |
WO2010033240A2 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
US20130197188A1 (en) * | 2010-03-15 | 2013-08-01 | Wolf-Georg Forssmann | Use of urodilatin for preparing a medicament for the treatment of cardiovascular, renal, pulmonary and neuronal syndromes while avoiding a rebound |
CA2823066A1 (en) | 2010-12-27 | 2012-07-05 | Alexion Pharma International Sarl | Compositions comprising natriuretic peptides and methods of use thereof |
WO2012115772A2 (en) * | 2011-02-25 | 2012-08-30 | Medtronic, Inc. | Therapy for kidney disease and/or heart failure |
US20150038418A1 (en) * | 2011-07-27 | 2015-02-05 | Medtronic, Inc. | Natriuretic peptide compositions and methods of preparation |
WO2013032784A1 (en) | 2011-08-30 | 2013-03-07 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
WO2013033675A1 (en) | 2011-09-02 | 2013-03-07 | Medtronic, Inc. | Chimeric natriuretic peptide compositions and methods of preparation |
US9611305B2 (en) | 2012-01-06 | 2017-04-04 | Mayo Foundation For Medical Education And Research | Treating cardiovascular or renal diseases |
US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
CA2898571A1 (en) * | 2013-01-25 | 2014-07-31 | Cardiorentis Ltd. | Methods of treating cardiovascular indications |
US10822596B2 (en) | 2014-07-11 | 2020-11-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for treating craniosynostosis |
MX2017007392A (es) | 2014-12-05 | 2019-01-24 | Alexion Pharma Inc | Tratamiento de convulsiones con fosfatasa alcalina recombinante. |
JP6868561B2 (ja) | 2015-01-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | アルカリホスファターゼ欠損を有する被験者を治療する方法 |
AU2016308624B2 (en) | 2015-08-17 | 2022-06-23 | Alexion Pharmaceuticals, Inc. | Manufacturing of alkaline phosphatases |
JP6868617B2 (ja) | 2015-09-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 低ホスファターゼ血症の組織非特異的アルカリホスファターゼ(tnsalp)酵素補充療法に有効な投薬計画の特定 |
EP3368062A4 (en) | 2015-10-30 | 2019-07-03 | Alexion Pharmaceuticals, Inc. | METHODS OF TREATING CRANIOSYNOSTOSIS IN A PATIENT |
US11065306B2 (en) | 2016-03-08 | 2021-07-20 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
EP3436052A4 (en) | 2016-04-01 | 2019-10-09 | Alexion Pharmaceuticals, Inc. | TREATMENT OF MUSCLE WEAKNESS USING ALKALINE PHOSPHATASES |
EP3436020A4 (en) | 2016-04-01 | 2019-12-25 | Alexion Pharmaceuticals, Inc. | METHOD FOR TREATING HYPOPHOSPHATASIE IN TEENS AND ADULTS |
US10988744B2 (en) | 2016-06-06 | 2021-04-27 | Alexion Pharmaceuticals, Inc. | Method of producing alkaline phosphatase |
US11116821B2 (en) | 2016-08-18 | 2021-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating tracheobronchomalacia |
AU2017368050A1 (en) | 2016-11-29 | 2019-06-20 | Puretech Lyt, Inc. | Exosomes for delivery of therapeutic agents |
EP3600383A4 (en) | 2017-03-31 | 2020-10-28 | Alexion Pharmaceuticals, Inc. | METHODS FOR TREATMENT OF HYPOPHOSPHATASIA (HPP) IN ADULTS AND ADOLESCENTS |
CN109838289B (zh) * | 2017-11-27 | 2022-03-15 | 罗伯特·博世有限公司 | 尿素水溶液喷射系统的回抽过程监测系统和方法 |
EP3773684A1 (en) | 2018-03-30 | 2021-02-17 | Alexion Pharmaceuticals, Inc. | Manufacturing of glycoproteins |
WO2021183928A1 (en) * | 2020-03-13 | 2021-09-16 | Mayo Foundation For Medical Education And Research | Assessing and treating acute decompensated heart failure |
WO2022029499A1 (en) * | 2020-08-06 | 2022-02-10 | Ads Aiphia Development Services Ag | Methods of treating refractory ascites |
EP4291224A1 (en) | 2021-02-12 | 2023-12-20 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
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DE3346953A1 (de) | 1983-12-24 | 1985-08-14 | Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg | Cardiodilatin, ein neues peptidhormon und verfahren zu seiner herstellung |
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US6831084B1 (en) | 1999-11-12 | 2004-12-14 | Wyeth | Branched adamantyl and noradamantyl aryl- and aralkylpiperazines with serotonin 5-HT1A activity |
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CA2425712C (en) | 2000-10-04 | 2017-06-06 | Molecular Medicine Research Institute | Methods of modulating apoptosis by administration of relaxin agonists or antagonists |
KR101271635B1 (ko) | 2001-12-21 | 2013-06-12 | 휴먼 게놈 사이언시즈, 인코포레이티드 | 알부민 융합 단백질 |
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BR112013003823A2 (pt) | 2010-08-20 | 2016-06-28 | Cerulean Pharma Inc | conjugados de peptídeo terapêutico-políemro, partículas, composições, e métodos relacionados |
-
2006
- 2006-04-07 EP EP06749753A patent/EP1865976B1/en active Active
- 2006-04-07 PT PT06749753T patent/PT1865976E/pt unknown
- 2006-04-07 WO PCT/US2006/013471 patent/WO2006110743A1/en active Application Filing
- 2006-04-07 PT PT121566962T patent/PT2510942E/pt unknown
- 2006-04-07 HU HUE12156696A patent/HUE026231T2/en unknown
- 2006-04-07 DK DK12156696.2T patent/DK2510942T3/en active
- 2006-04-07 PL PL12156696T patent/PL2510942T3/pl unknown
- 2006-04-07 EP EP12156696.2A patent/EP2510942B1/en active Active
- 2006-04-07 US US11/400,696 patent/US7732406B2/en active Active
- 2006-04-07 ES ES06749753T patent/ES2392892T3/es active Active
- 2006-04-07 PL PL06749753T patent/PL1865976T3/pl unknown
- 2006-04-07 DK DK06749753.7T patent/DK1865976T3/da active
- 2006-04-07 SI SI200632000T patent/SI2510942T1/sl unknown
- 2006-04-07 ES ES12156696.2T patent/ES2554713T3/es active Active
-
2010
- 2010-04-26 US US12/767,395 patent/US8710006B2/en active Active
-
2012
- 2012-07-23 CY CY20121100652T patent/CY1113183T1/el unknown
-
2014
- 2014-03-18 US US14/218,389 patent/US9023794B2/en active Active
-
2015
- 2015-02-26 US US14/632,350 patent/US9358271B2/en active Active
-
2016
- 2016-05-11 US US15/152,220 patent/US20160324931A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US9358271B2 (en) | 2016-06-07 |
PL2510942T3 (pl) | 2016-02-29 |
WO2006110743A1 (en) | 2006-10-19 |
US20140287999A1 (en) | 2014-09-25 |
EP1865976A1 (en) | 2007-12-19 |
US8710006B2 (en) | 2014-04-29 |
PL1865976T3 (pl) | 2012-11-30 |
US20160324931A1 (en) | 2016-11-10 |
EP2510942A1 (en) | 2012-10-17 |
US20110257099A1 (en) | 2011-10-20 |
EP2510942B1 (en) | 2015-09-02 |
EP1865976B1 (en) | 2012-05-23 |
PT1865976E (pt) | 2012-08-03 |
PT2510942E (pt) | 2015-12-28 |
DK2510942T3 (en) | 2015-12-14 |
US9023794B2 (en) | 2015-05-05 |
ES2554713T3 (es) | 2015-12-22 |
US20150224174A1 (en) | 2015-08-13 |
HUE026231T2 (en) | 2016-06-28 |
SI2510942T1 (sl) | 2016-01-29 |
EP1865976A4 (en) | 2010-09-01 |
ES2392892T3 (es) | 2012-12-14 |
US7732406B2 (en) | 2010-06-08 |
DK1865976T3 (da) | 2012-07-23 |
US20060264376A1 (en) | 2006-11-23 |
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