CY1112791T1 - Φαρμακευτικη χημικη συνθεση ζονισαμιδης παρατεταμενης αποδεσμευσης - Google Patents
Φαρμακευτικη χημικη συνθεση ζονισαμιδης παρατεταμενης αποδεσμευσηςInfo
- Publication number
- CY1112791T1 CY1112791T1 CY20121100482T CY121100482T CY1112791T1 CY 1112791 T1 CY1112791 T1 CY 1112791T1 CY 20121100482 T CY20121100482 T CY 20121100482T CY 121100482 T CY121100482 T CY 121100482T CY 1112791 T1 CY1112791 T1 CY 1112791T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pharmaceutical chemical
- zonisamid
- preservation
- chemical composition
- zonisamide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Φαρμακευτικές χημικές συνθέσεις περιλαμβάνουν ζονισαμίδη παρατεταμένης αποδέσμευσης. Μέθοδοι παρασκευής τέτοιων φαρμακευτικών χημικών συνθέσεων ενέχουν την ανάμειξη ζονισαμίδης με ένα κατάλληλο έκδοχο σχηματισμένο έτσι ώστε να ελέγχει το προφίλ διαλυτοποίησης της ζονισαμίδης. Μέθοδοι αγωγής ενέχουν την χορήγηση των φαρμακευτικών χημικών συνθέσεων σε ασθενείς που χρήζουν τέτοιας αγωγής.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74003405P | 2005-11-28 | 2005-11-28 | |
US83211006P | 2006-07-19 | 2006-07-19 | |
US83556406P | 2006-08-04 | 2006-08-04 | |
EP06838427A EP1954241B1 (en) | 2005-11-28 | 2006-11-27 | Sustained-release formulation of zonisamide |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1112791T1 true CY1112791T1 (el) | 2016-02-10 |
Family
ID=37898367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100482T CY1112791T1 (el) | 2005-11-28 | 2012-05-28 | Φαρμακευτικη χημικη συνθεση ζονισαμιδης παρατεταμενης αποδεσμευσης |
Country Status (12)
Country | Link |
---|---|
US (3) | US20070148237A1 (el) |
EP (1) | EP1954241B1 (el) |
JP (4) | JP2009517394A (el) |
AR (1) | AR057946A1 (el) |
AT (1) | ATE547097T1 (el) |
CY (1) | CY1112791T1 (el) |
DK (1) | DK1954241T3 (el) |
ES (1) | ES2383330T3 (el) |
PL (1) | PL1954241T3 (el) |
PT (1) | PT1954241E (el) |
TW (1) | TWI425944B (el) |
WO (1) | WO2007062228A1 (el) |
Families Citing this family (21)
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PT2316456T (pt) | 2003-04-29 | 2017-09-05 | Orexigen Therapeutics Inc | Composições para afetar a perda de peso compreendendo naltrexona e bupropion |
DK2135603T3 (da) | 2005-11-22 | 2013-03-25 | Orexigen Therapeutics Inc | Sammensætninger og fremgangsmåder til øgning af insulinsensitivitet |
WO2007089318A2 (en) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions and methods for reducing food cravings |
US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
AU2007319472B2 (en) | 2006-11-09 | 2013-01-17 | Nalpropion Pharmaceuticals Llc | Methods Of Administering Weight Loss Medications |
CN101588795A (zh) * | 2006-11-09 | 2009-11-25 | 奥雷西根治疗公司 | 包含中间快速溶解层的分层药物制剂 |
KR20110071050A (ko) * | 2008-04-29 | 2011-06-28 | 파넥스트 | 알츠하이머 질환 및 관련 장애의 치료를 위한 조니사미드 및 아캄프로세이트의 조합 조성물 |
US20110144145A1 (en) | 2008-05-30 | 2011-06-16 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
BRPI0912161A2 (pt) * | 2008-05-30 | 2015-10-06 | Ucb Pharma Sa | composição farmacêutica na forma de um tablete |
BRPI0921078A2 (pt) * | 2008-11-20 | 2015-12-15 | Avantor Performance Mat Inc | excipiente coprocessado à base de fosfato de cálcio dibásico granular de alta funcionalidade e diretamente compressível. |
DE102009035649A1 (de) * | 2009-07-29 | 2011-02-03 | Siemens Aktiengesellschaft | Arzneistoff und Verfahren zur Erprobung eines Arzneistoffes |
AU2011203867B2 (en) | 2010-01-11 | 2015-12-03 | Nalpropion Pharmaceuticals Llc | Methods of providing weight loss therapy in patients with major depression |
EP2858640B1 (en) | 2012-06-06 | 2020-03-25 | Nalpropion Pharmaceuticals LLC | Composition for use in a method of treating overweight and obesity in patients with high cardiovascular risk |
CA2879603A1 (en) * | 2012-07-27 | 2014-01-30 | Ratiopharm Gmbh | Oral dosage forms for modified release comprising ruxolitinib |
BR112018068143A2 (pt) * | 2016-03-09 | 2019-07-30 | Nls 1 Pharma Ag | forma farmacêutica unitária oral de mazindol na forma de comprimido do tipo multicamada e processo para preparar dita forma farmacêutica |
EP3470065A4 (en) * | 2016-06-09 | 2020-03-18 | DS Pharma Animal Health Co. Ltd. | EXTENDED RELEASE PREPARATION COMPOSITION FOR ANIMALS |
WO2019038584A1 (en) | 2017-08-19 | 2019-02-28 | Ftf Pharma Private Limited | ORAL PHARMACEUTICAL COMPOSITION COMPRISING ZONISAMIDE AND PREPARATION METHOD THEREOF |
WO2020214879A1 (en) * | 2019-04-19 | 2020-10-22 | Steven Hoffman | Sustained release formulations |
WO2021053542A1 (en) * | 2019-09-20 | 2021-03-25 | Dr. Reddy’S Laboratories Limited | Pharmaceutical compositions for obesity management |
CN114344271B (zh) * | 2022-01-18 | 2022-08-30 | 深圳市资福药业有限公司 | 一种唑尼沙胺片的制备方法 |
WO2024073334A1 (en) | 2022-09-26 | 2024-04-04 | Rose Research Center, Llc | Combination for use in a method of preventing weight gain |
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-
2006
- 2006-11-27 AR ARP060105223A patent/AR057946A1/es unknown
- 2006-11-27 DK DK06838427.0T patent/DK1954241T3/da active
- 2006-11-27 TW TW095143747A patent/TWI425944B/zh active
- 2006-11-27 ES ES06838427T patent/ES2383330T3/es active Active
- 2006-11-27 PT PT06838427T patent/PT1954241E/pt unknown
- 2006-11-27 US US11/563,618 patent/US20070148237A1/en not_active Abandoned
- 2006-11-27 EP EP06838427A patent/EP1954241B1/en active Active
- 2006-11-27 PL PL06838427T patent/PL1954241T3/pl unknown
- 2006-11-27 WO PCT/US2006/045445 patent/WO2007062228A1/en active Application Filing
- 2006-11-27 JP JP2008542471A patent/JP2009517394A/ja active Pending
- 2006-11-27 AT AT06838427T patent/ATE547097T1/de active
-
2012
- 2012-05-28 CY CY20121100482T patent/CY1112791T1/el unknown
-
2013
- 2013-05-08 JP JP2013098463A patent/JP6169411B2/ja active Active
- 2013-08-13 US US13/966,129 patent/US20140080857A1/en not_active Abandoned
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2015
- 2015-10-08 JP JP2015200370A patent/JP2016011308A/ja active Pending
-
2016
- 2016-01-22 US US15/004,269 patent/US20160354348A1/en not_active Abandoned
-
2017
- 2017-02-15 JP JP2017025683A patent/JP2017082013A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US20160354348A1 (en) | 2016-12-08 |
JP6169411B2 (ja) | 2017-07-26 |
WO2007062228A1 (en) | 2007-05-31 |
JP2016011308A (ja) | 2016-01-21 |
JP2013147513A (ja) | 2013-08-01 |
ATE547097T1 (de) | 2012-03-15 |
US20140080857A1 (en) | 2014-03-20 |
ES2383330T3 (es) | 2012-06-20 |
PL1954241T3 (pl) | 2013-03-29 |
AR057946A1 (es) | 2007-12-26 |
PT1954241E (pt) | 2012-06-01 |
DK1954241T3 (da) | 2012-06-18 |
EP1954241B1 (en) | 2012-02-29 |
TW200806289A (en) | 2008-02-01 |
US20070148237A1 (en) | 2007-06-28 |
EP1954241A1 (en) | 2008-08-13 |
JP2017082013A (ja) | 2017-05-18 |
TWI425944B (zh) | 2014-02-11 |
JP2009517394A (ja) | 2009-04-30 |
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