CY1111476T1 - Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca - Google Patents
Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vincaInfo
- Publication number
- CY1111476T1 CY1111476T1 CY20101100917T CY101100917T CY1111476T1 CY 1111476 T1 CY1111476 T1 CY 1111476T1 CY 20101100917 T CY20101100917 T CY 20101100917T CY 101100917 T CY101100917 T CY 101100917T CY 1111476 T1 CY1111476 T1 CY 1111476T1
- Authority
- CY
- Cyprus
- Prior art keywords
- halogonated
- mitotic
- derivatives
- vinca alkaloids
- vinca
- Prior art date
Links
- 229940122803 Vinca alkaloid Drugs 0.000 title 1
- 230000002927 anti-mitotic effect Effects 0.000 title 1
- YIHUEPHBPPAAHH-IIQAEXPMSA-N 33mg53c7xw Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.C([C@@](C1=C(C2=CC=CC=C2N1)C1)(C2=C(OC)C=C3N(C)[C@@H]4[C@@]5(C3=C2)CCN2CC=C[C@]([C@@H]52)([C@H]([C@]4(O)C(=O)OC)OC(C)=O)CC)C(=O)OC)[C@@H]2C[C@@H](C(C)(F)F)CN1C2 YIHUEPHBPPAAHH-IIQAEXPMSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9704398A FR2761990B1 (fr) | 1997-04-10 | 1997-04-10 | Derives halogenes antimitotiques d'alcaloides de vinca |
| EP98920607A EP0975640B1 (fr) | 1997-04-10 | 1998-04-10 | Derives halogenes antimitotiques d'alcaloides de vinca |
| EP20030017052 EP1357125A3 (fr) | 1997-04-10 | 1998-04-10 | Procédé de préparation de dérivés halogénés d'alcaloides de vinca |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111476T1 true CY1111476T1 (el) | 2012-01-25 |
Family
ID=9505731
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20101100917T CY1111476T1 (el) | 1997-04-10 | 2010-10-14 | Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca |
| CY2010019C CY2010019I1 (el) | 1997-04-10 | 2010-12-22 | Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY2010019C CY2010019I1 (el) | 1997-04-10 | 2010-12-22 | Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6127377A (enExample) |
| EP (3) | EP1764368B1 (enExample) |
| JP (3) | JP4401440B2 (enExample) |
| AT (2) | ATE473987T1 (enExample) |
| AU (1) | AU737549C (enExample) |
| BR (2) | BR9816177B1 (enExample) |
| CA (3) | CA2665949C (enExample) |
| CY (2) | CY1111476T1 (enExample) |
| DE (3) | DE69824840T2 (enExample) |
| DK (2) | DK0975640T3 (enExample) |
| ES (2) | ES2222588T3 (enExample) |
| FR (2) | FR2761990B1 (enExample) |
| LU (1) | LU91769I2 (enExample) |
| PT (2) | PT1764368E (enExample) |
| WO (1) | WO1998045301A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2761990B1 (fr) * | 1997-04-10 | 1999-06-25 | Pf Medicament | Derives halogenes antimitotiques d'alcaloides de vinca |
| US6890558B2 (en) * | 2002-05-31 | 2005-05-10 | R.P. Scherer Technologies, Inc. | Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment |
| EP1694330A4 (en) * | 2003-12-04 | 2009-06-24 | Amr Technology Inc | DERIVATIVES OF VINORELBINE |
| NZ547370A (en) * | 2003-12-04 | 2010-09-30 | Amr Technology Inc | Vinca derivatives |
| US20110015221A1 (en) * | 2003-12-23 | 2011-01-20 | Pierre Fabre Medicament | Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same |
| FR2863891B1 (fr) * | 2003-12-23 | 2006-03-24 | Pf Medicament | Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation |
| CA2607940C (en) | 2005-05-18 | 2009-12-15 | Aegera Therapeutics Inc. | Bir domain binding compounds |
| FR2894966B1 (fr) * | 2005-12-20 | 2008-03-14 | Pierre Fabre Medicament Sa | Nouvelle forme cristalline de la vinflunine |
| MY159563A (en) | 2006-05-16 | 2017-01-13 | Pharmascience Inc | Iap bir domain binding compounds |
| US20080125451A1 (en) * | 2006-09-12 | 2008-05-29 | Amr Technology, Inc. | Vinorelbine derivatives |
| US8039453B2 (en) * | 2006-09-12 | 2011-10-18 | Albany Molecular Research, Inc. | Vinca derivatives |
| FR2905949B1 (fr) * | 2006-09-20 | 2008-11-21 | Pierre Fabre Medicament Sa | Derives fluores de catharanthine, leur preparation et leur utilisation comme precurseurs d'alcaloides dimeres de vinca |
| FR2910812B1 (fr) | 2006-12-29 | 2009-03-20 | Pierre Fabre Medicament Sa | Compositions pharmaceutiques injectables lyophilisees de derives hemi-synthetiques d'alcaloide de vinca stables a temperature ambiante |
| FR2912406B1 (fr) | 2007-02-13 | 2009-05-08 | Pierre Fabre Medicament Sa | Sels cristalins anhydres de vinflunine, procede de preparation et utilisation en tant que medicament et moyen de purification de la vinflunine. |
| FR2918566B1 (fr) * | 2007-07-11 | 2009-10-09 | Pierre Fabre Medicament Sa | Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine. |
| FR2918567B1 (fr) * | 2007-07-11 | 2012-08-03 | Pf Medicament | Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine. |
| US20090076055A1 (en) * | 2007-09-14 | 2009-03-19 | Protia, Llc | Deuterium-enriched vinflunine |
| DE102010020994B4 (de) * | 2010-01-27 | 2022-01-27 | Interpane Entwicklungs-Und Beratungsgesellschaft Mbh | Verfahren zur Herstellung eines beschichteten Gegenstands mit Texturätzen |
| NZ602368A (en) | 2010-02-12 | 2014-10-31 | Pharmascience Inc | Iap bir domain binding compounds |
| US8940754B2 (en) | 2010-02-22 | 2015-01-27 | The Scripps Research Institute | 10′-fluorinated Vinca alkaloids provide enhanced biological activity against MDR cancer cells |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2707988B1 (fr) * | 1993-07-21 | 1995-10-13 | Pf Medicament | Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant. |
| FR2761990B1 (fr) * | 1997-04-10 | 1999-06-25 | Pf Medicament | Derives halogenes antimitotiques d'alcaloides de vinca |
-
1997
- 1997-04-10 FR FR9704398A patent/FR2761990B1/fr not_active Expired - Lifetime
-
1998
- 1998-04-10 EP EP06124480A patent/EP1764368B1/fr not_active Expired - Lifetime
- 1998-04-10 DE DE69824840T patent/DE69824840T2/de not_active Expired - Lifetime
- 1998-04-10 AT AT06124480T patent/ATE473987T1/de active
- 1998-04-10 AU AU73408/98A patent/AU737549C/en not_active Expired
- 1998-04-10 US US09/402,678 patent/US6127377A/en not_active Expired - Lifetime
- 1998-04-10 EP EP20030017052 patent/EP1357125A3/fr not_active Ceased
- 1998-04-10 BR BRPI9816177-6A patent/BR9816177B1/pt not_active IP Right Cessation
- 1998-04-10 JP JP54247098A patent/JP4401440B2/ja not_active Expired - Lifetime
- 1998-04-10 CA CA2665949A patent/CA2665949C/fr not_active Expired - Lifetime
- 1998-04-10 DK DK98920607T patent/DK0975640T3/da active
- 1998-04-10 EP EP98920607A patent/EP0975640B1/fr not_active Expired - Lifetime
- 1998-04-10 DE DE69841766T patent/DE69841766D1/de not_active Expired - Lifetime
- 1998-04-10 ES ES98920607T patent/ES2222588T3/es not_active Expired - Lifetime
- 1998-04-10 PT PT06124480T patent/PT1764368E/pt unknown
- 1998-04-10 CA CA002286560A patent/CA2286560C/fr not_active Expired - Lifetime
- 1998-04-10 ES ES06124480T patent/ES2347878T3/es not_active Expired - Lifetime
- 1998-04-10 AT AT98920607T patent/ATE270297T1/de active
- 1998-04-10 WO PCT/FR1998/000730 patent/WO1998045301A1/fr not_active Ceased
- 1998-04-10 PT PT98920607T patent/PT975640E/pt unknown
- 1998-04-10 DK DK06124480.2T patent/DK1764368T3/da active
- 1998-04-10 CA CA2455416A patent/CA2455416C/fr not_active Expired - Lifetime
- 1998-04-10 DE DE122010000054C patent/DE122010000054I1/de active Pending
- 1998-04-10 BR BRPI9807944-1A patent/BR9807944B1/pt not_active IP Right Cessation
-
2004
- 2004-03-03 JP JP2004059502A patent/JP4307292B2/ja not_active Expired - Lifetime
-
2009
- 2009-03-11 JP JP2009058098A patent/JP2009167196A/ja active Pending
-
2010
- 2010-09-27 FR FR10C0045C patent/FR10C0045I2/fr active Active
- 2010-10-14 CY CY20101100917T patent/CY1111476T1/el unknown
- 2010-12-22 LU LU91769C patent/LU91769I2/fr unknown
- 2010-12-22 CY CY2010019C patent/CY2010019I1/el unknown
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