CY1111476T1 - Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca - Google Patents

Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca

Info

Publication number
CY1111476T1
CY1111476T1 CY20101100917T CY101100917T CY1111476T1 CY 1111476 T1 CY1111476 T1 CY 1111476T1 CY 20101100917 T CY20101100917 T CY 20101100917T CY 101100917 T CY101100917 T CY 101100917T CY 1111476 T1 CY1111476 T1 CY 1111476T1
Authority
CY
Cyprus
Prior art keywords
halogonated
mitotic
derivatives
vinca alkaloids
vinca
Prior art date
Application number
CY20101100917T
Other languages
Greek (el)
English (en)
Inventor
Alain Duflos
Jacques Fahy
Valerie Thillaye Du Boullay
Jean-Marc Barret
Bridget Hill
Original Assignee
Pierre Fabre Medicament Production
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament Production filed Critical Pierre Fabre Medicament Production
Publication of CY1111476T1 publication Critical patent/CY1111476T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CY20101100917T 1997-04-10 2010-10-14 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca CY1111476T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9704398A FR2761990B1 (fr) 1997-04-10 1997-04-10 Derives halogenes antimitotiques d'alcaloides de vinca
EP98920607A EP0975640B1 (fr) 1997-04-10 1998-04-10 Derives halogenes antimitotiques d'alcaloides de vinca
EP20030017052 EP1357125A3 (fr) 1997-04-10 1998-04-10 Procédé de préparation de dérivés halogénés d'alcaloides de vinca

Publications (1)

Publication Number Publication Date
CY1111476T1 true CY1111476T1 (el) 2012-01-25

Family

ID=9505731

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20101100917T CY1111476T1 (el) 1997-04-10 2010-10-14 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca
CY2010019C CY2010019I2 (el) 1997-04-10 2010-12-22 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY2010019C CY2010019I2 (el) 1997-04-10 2010-12-22 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca

Country Status (15)

Country Link
US (1) US6127377A (enExample)
EP (3) EP0975640B1 (enExample)
JP (3) JP4401440B2 (enExample)
AT (2) ATE270297T1 (enExample)
AU (1) AU737549C (enExample)
BR (2) BR9807944B1 (enExample)
CA (3) CA2665949C (enExample)
CY (2) CY1111476T1 (enExample)
DE (3) DE122010000054I1 (enExample)
DK (2) DK1764368T3 (enExample)
ES (2) ES2347878T3 (enExample)
FR (2) FR2761990B1 (enExample)
LU (1) LU91769I2 (enExample)
PT (2) PT1764368E (enExample)
WO (1) WO1998045301A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca
US6890558B2 (en) * 2002-05-31 2005-05-10 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
AU2004296191B2 (en) * 2003-12-04 2010-10-28 Albany Molecular Research, Inc. Vinca derivatives
US7235564B2 (en) * 2003-12-04 2007-06-26 Amr Technology, Inc. Vinorelbine derivatives
US20110015221A1 (en) * 2003-12-23 2011-01-20 Pierre Fabre Medicament Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same
FR2863891B1 (fr) * 2003-12-23 2006-03-24 Pf Medicament Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation
WO2006122408A1 (en) 2005-05-18 2006-11-23 Aegera Therapeutics Inc. Bir domain binding compounds
FR2894966B1 (fr) 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa Nouvelle forme cristalline de la vinflunine
BRPI0711591A2 (pt) 2006-05-16 2011-11-16 Aegera Therapeutics, Inc. composto de ligação de domìnio bir da iap
WO2008033930A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinca derivatives
WO2008033935A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinorelbine derivatives
FR2905949B1 (fr) * 2006-09-20 2008-11-21 Pierre Fabre Medicament Sa Derives fluores de catharanthine, leur preparation et leur utilisation comme precurseurs d'alcaloides dimeres de vinca
FR2910812B1 (fr) * 2006-12-29 2009-03-20 Pierre Fabre Medicament Sa Compositions pharmaceutiques injectables lyophilisees de derives hemi-synthetiques d'alcaloide de vinca stables a temperature ambiante
FR2912406B1 (fr) * 2007-02-13 2009-05-08 Pierre Fabre Medicament Sa Sels cristalins anhydres de vinflunine, procede de preparation et utilisation en tant que medicament et moyen de purification de la vinflunine.
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
US20090076055A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched vinflunine
DE102010020994B4 (de) * 2010-01-27 2022-01-27 Interpane Entwicklungs-Und Beratungsgesellschaft Mbh Verfahren zur Herstellung eines beschichteten Gegenstands mit Texturätzen
NZ602368A (en) 2010-02-12 2014-10-31 Pharmascience Inc Iap bir domain binding compounds
JP5542972B2 (ja) * 2010-02-22 2014-07-09 ザ スクリプス リサーチ インスティテュート Ｍｄｒがん細胞に対する強化された生物活性を提供する１０’−フッ素化ビンカアルカロイド
WO2026064520A1 (en) 2024-09-19 2026-03-26 Tesseract Medicines Us, Llc Covalent-induced drug conjugates targeting kras and comprising a tubulin inhibitor payload
WO2026064527A1 (en) 2024-09-19 2026-03-26 Tesseract Medicines Us, Llc Kras-targeting covalent-induced drug conjugates comprising a tubulin inhibitor payload

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707988B1 (fr) * 1993-07-21 1995-10-13 Pf Medicament Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca

Also Published As

Publication number Publication date
PT1764368E (pt) 2010-09-16
DE69824840D1 (de) 2004-08-05
EP1764368B1 (fr) 2010-07-14
US6127377A (en) 2000-10-03
AU737549C (en) 2002-03-28
FR10C0045I1 (enExample) 2010-10-29
FR10C0045I2 (fr) 2011-04-29
JP4307292B2 (ja) 2009-08-05
CA2665949C (fr) 2013-06-11
CA2455416C (fr) 2010-11-02
DK0975640T3 (da) 2004-11-01
BR9807944A (pt) 2000-03-08
EP1357125A2 (fr) 2003-10-29
DE69841766D1 (de) 2010-08-26
EP1357125A3 (fr) 2003-11-26
DK1764368T3 (da) 2010-10-18
AU737549B2 (en) 2001-08-23
FR2761990A1 (fr) 1998-10-16
ES2222588T3 (es) 2005-02-01
LU91769I2 (fr) 2011-02-22
CA2286560C (fr) 2009-09-08
CA2455416A1 (fr) 1998-10-15
DE69824840T2 (de) 2005-07-21
BR9816177B1 (pt) 2010-08-24
BR9807944B1 (pt) 2011-02-08
PT975640E (pt) 2004-11-30
JP2001518892A (ja) 2001-10-16
EP0975640B1 (fr) 2004-06-30
ATE473987T1 (de) 2010-07-15
CY2010019I1 (el) 2012-01-25
WO1998045301A1 (fr) 1998-10-15
EP1764368A1 (fr) 2007-03-21
EP0975640A1 (fr) 2000-02-02
CY2010019I2 (el) 2012-01-25
CA2665949A1 (fr) 1998-10-15
JP2009167196A (ja) 2009-07-30
DE122010000054I1 (de) 2011-05-05
JP2004277418A (ja) 2004-10-07
AU7340898A (en) 1998-10-30
JP4401440B2 (ja) 2010-01-20
ATE270297T1 (de) 2004-07-15
ES2347878T3 (es) 2010-11-22
FR2761990B1 (fr) 1999-06-25
CA2286560A1 (fr) 1998-10-15

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