CU23885B1 - Estratrienos 8-beta sustituidos como estrógenos de acción selectiva - Google Patents

Estratrienos 8-beta sustituidos como estrógenos de acción selectiva

Info

Publication number
CU23885B1
CU23885B1 CU20100008A CU20100008A CU23885B1 CU 23885 B1 CU23885 B1 CU 23885B1 CU 20100008 A CU20100008 A CU 20100008A CU 20100008 A CU20100008 A CU 20100008A CU 23885 B1 CU23885 B1 CU 23885B1
Authority
CU
Cuba
Prior art keywords
stratriens
strateges
selective action
beta substituted
beta
Prior art date
Application number
CU20100008A
Other languages
English (en)
Other versions
CU20100008A7 (es
Inventor
Ina Thieme
Nico Braeuer
Katja Prelle
Olaf Peters
Hans-Peter Muhn
Karl-Heinrich Fritzemeier
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of CU20100008A7 publication Critical patent/CU20100008A7/es
Publication of CU23885B1 publication Critical patent/CU23885B1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CU20100008A 2007-07-12 2010-01-12 Estratrienos 8-beta sustituidos como estrógenos de acción selectiva CU23885B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07075600A EP2014672A1 (en) 2007-07-12 2007-07-12 8-beta-substituted estratrienes as selectively active estrogens
PCT/EP2008/059115 WO2009007454A2 (en) 2007-07-12 2008-07-11 8-beta-substituted estratrienes as selectively active estrogens

Publications (2)

Publication Number Publication Date
CU20100008A7 CU20100008A7 (es) 2011-05-27
CU23885B1 true CU23885B1 (es) 2013-04-19

Family

ID=38657613

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20100008A CU23885B1 (es) 2007-07-12 2010-01-12 Estratrienos 8-beta sustituidos como estrógenos de acción selectiva

Country Status (34)

Country Link
US (1) US20090029957A1 (es)
EP (2) EP2014672A1 (es)
JP (1) JP2010533152A (es)
KR (1) KR20100037593A (es)
CN (1) CN101687902B (es)
AR (1) AR067507A1 (es)
AU (1) AU2008274198A1 (es)
BR (1) BRPI0814207A2 (es)
CA (1) CA2692727A1 (es)
CL (1) CL2008002027A1 (es)
CO (1) CO6270230A2 (es)
CR (1) CR11211A (es)
CU (1) CU23885B1 (es)
CY (1) CY1113351T1 (es)
DK (1) DK2176282T3 (es)
DO (1) DOP2010000017A (es)
EA (1) EA017124B1 (es)
EC (1) ECSP109872A (es)
ES (1) ES2393942T3 (es)
HN (1) HN2010000081A (es)
HR (1) HRP20120952T1 (es)
MA (1) MA31565B1 (es)
NZ (1) NZ582490A (es)
PA (1) PA8789401A1 (es)
PE (1) PE20090825A1 (es)
PL (1) PL2176282T3 (es)
PT (1) PT2176282E (es)
RS (1) RS52541B (es)
SI (1) SI2176282T1 (es)
TN (1) TN2010000007A1 (es)
TW (1) TW200911824A (es)
UA (1) UA99918C2 (es)
UY (1) UY31220A1 (es)
WO (1) WO2009007454A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012129673A1 (en) * 2011-03-25 2012-10-04 Universite Laval INHIBITORS OF 17ß-HSD1, 17ß-HSD3 AND 17ß-HSD10
EP3474965A4 (en) * 2016-06-24 2020-02-05 K & N Engineering, Inc. COMPOSED AIR FILTER AND METHOD THEREFOR
USD905747S1 (en) 2018-04-09 2020-12-22 Mitsubishi Electric Corporation Display screen with animated graphical user interface

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10019167A1 (de) * 2000-04-12 2001-10-18 Schering Ag Substituierte Estratriene als selektiv wirksame Estrogene
CN100453549C (zh) * 2000-04-12 2009-01-21 舍林股份公司 作为具选择活性的雌激素的8β-烃基取代的雌三烯

Also Published As

Publication number Publication date
PT2176282E (pt) 2012-11-30
PE20090825A1 (es) 2009-07-25
CO6270230A2 (es) 2011-04-20
EP2176282B1 (en) 2012-08-22
US20090029957A1 (en) 2009-01-29
DK2176282T3 (da) 2012-12-03
WO2009007454A2 (en) 2009-01-15
EA017124B1 (ru) 2012-10-30
EA201000097A1 (ru) 2010-08-30
NZ582490A (en) 2012-03-30
UY31220A1 (es) 2009-03-02
PL2176282T3 (pl) 2013-06-28
HRP20120952T1 (hr) 2012-12-31
ECSP109872A (es) 2010-02-26
CY1113351T1 (el) 2016-06-22
KR20100037593A (ko) 2010-04-09
TN2010000007A1 (en) 2011-09-26
BRPI0814207A2 (pt) 2015-01-27
TW200911824A (en) 2009-03-16
AU2008274198A1 (en) 2009-01-15
WO2009007454A3 (en) 2009-03-05
ES2393942T3 (es) 2013-01-02
CN101687902A (zh) 2010-03-31
CR11211A (es) 2010-04-27
CA2692727A1 (en) 2009-01-15
CU20100008A7 (es) 2011-05-27
EP2014672A1 (en) 2009-01-14
JP2010533152A (ja) 2010-10-21
CN101687902B (zh) 2013-07-24
DOP2010000017A (es) 2010-01-31
UA99918C2 (ru) 2012-10-25
SI2176282T1 (sl) 2013-02-28
AR067507A1 (es) 2009-10-14
CL2008002027A1 (es) 2009-01-16
PA8789401A1 (es) 2009-04-23
HN2010000081A (es) 2013-07-01
RS52541B (en) 2013-04-30
MA31565B1 (fr) 2010-08-02
EP2176282A2 (en) 2010-04-21

Similar Documents

Publication Publication Date Title
NO2021006I1 (no) Quofenix, delafloksacin
BRPI0922845A2 (pt) pirazol-4-n-alcoxicarboxamidas como microbiocidas
BRPI0921327A2 (pt) Combinação de herbicida-protetor
BRPI0919295A2 (pt) 1h-benzimidazol-5-carboxamidas como agentes anti-inflamatórios.
BRPI0810462A2 (pt) Derivados de quinolina-carboxamida como antagonistas de p2y12
CR10926A (es) Nuevas 2-aminooxazolinas como ligandos taar1
BRPI0818380A2 (pt) Combinação de herbicida-protetor
DK2340021T3 (da) Substituerede pyrrolidin-2-carboxamider
DK2268893T3 (da) Selektivt skråtstillet perforering
BRPI1009415A2 (pt) escova de dentes.
BRPI0918562A2 (pt) estrutura de tecido
BRPI0918603A2 (pt) pirrolidin-2-onas como ligantes de hdm2
BRPI1008939A2 (pt) 2-mercaptoquinolina-3-carboxamidas substituídas como moduladores de kncq2/3.
BRPI0922939A2 (pt) n-oxiamidas espiro-heterocíclicas como pesticidas
BRPI0912808A2 (pt) aperfeiçoamentos em poços de alimentação
BRPI1014077A2 (pt) Derivados de tiazolilperidina como fungicidas
DK2344471T3 (da) 7-piperidinalkyl-3,4-dihydroquinolon-derivat
BRPI0812387A2 (pt) Macadores de polinucleotídeo
DE112009000578A5 (de) Reibahle
ATE527260T1 (de) (dihydro)pyrroloä2,1-aüisoquinoline
BRPI0915562A2 (pt) tamis melhorado
BRPI0915442A2 (pt) tamis melhorado
BRPI0917673A2 (pt) Combinação de herbicida-protetor compreendendo difluorometanossulfonilanilidas substituidas por dimetoxitriazinila
FR2947857B1 (fr) Agencement de deshuileur
BRPI0822525A2 (pt) gerar mapas de sites

Legal Events

Date Code Title Description
FG Grant of patent
FD Lapse (for not paying fees)