CS44091A3 - 1-phenylimidazole derivative, process of its preparation and use - Google Patents
1-phenylimidazole derivative, process of its preparation and useInfo
- Publication number
- CS44091A3 CS44091A3 CS91440A CS44091A CS44091A3 CS 44091 A3 CS44091 A3 CS 44091A3 CS 91440 A CS91440 A CS 91440A CS 44091 A CS44091 A CS 44091A CS 44091 A3 CS44091 A3 CS 44091A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- preparation
- phenylimidazole derivative
- phenylimidazole
- derivative
- Prior art date
Links
- 150000004842 1-phenylimidazoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17313590 | 1990-06-29 | ||
| JP23543990 | 1990-09-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS44091A3 true CS44091A3 (en) | 1992-02-19 |
| CZ279536B6 CZ279536B6 (cs) | 1995-05-17 |
Family
ID=26495230
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5153215A (cs) |
| EP (2) | EP0464980B1 (cs) |
| KR (2) | KR920000745A (cs) |
| AU (2) | AU633184B2 (cs) |
| BR (2) | BR9100663A (cs) |
| CA (2) | CA2036148A1 (cs) |
| CZ (2) | CZ279536B6 (cs) |
| DE (2) | DE69103230T2 (cs) |
| ES (2) | ES2057754T3 (cs) |
| HU (2) | HUT58058A (cs) |
| IL (2) | IL97279A (cs) |
| MY (2) | MY104627A (cs) |
| SK (1) | SK278039B6 (cs) |
| YU (2) | YU30391A (cs) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY106533A (en) * | 1990-02-20 | 1995-06-30 | Sumitomo Chemical Co | A 4-tert.-butyl imidazole derivative and its production and use. |
| CA2036148A1 (en) * | 1990-06-29 | 1991-12-30 | Hiroki Tomioka | A 1-phenylimidazole derivative and its production and use |
| US5252590A (en) * | 1991-06-28 | 1993-10-12 | Sumitomo Chemical Company, Limited | 1-pyridylimidazole derivative |
| EP0599183A1 (en) * | 1992-11-25 | 1994-06-01 | Rhone-Poulenc Agrochimie | Manufacturing of pesticides and intermediates |
| JP3715994B2 (ja) * | 1993-12-21 | 2005-11-16 | 住友化学株式会社 | 害虫防除剤 |
| US6413542B1 (en) | 1996-03-29 | 2002-07-02 | Merial | Direct pour-on antiparasitic skin solution and methods for treating, preventing and controlling myasis |
| US6733767B2 (en) * | 1998-03-19 | 2004-05-11 | Merck & Co., Inc. | Liquid polymeric compositions for controlled release of bioactive substances |
| US6787342B2 (en) | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
| US20040077703A1 (en) * | 2002-10-02 | 2004-04-22 | Soll Mark D. | Nodulisporic acid derivative spot-on formulations for combating parasites |
| US7262214B2 (en) | 2003-02-26 | 2007-08-28 | Merial Limited | 1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases |
| US7531186B2 (en) * | 2003-12-17 | 2009-05-12 | Merial Limited | Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz |
| US20050234119A1 (en) * | 2004-04-16 | 2005-10-20 | Soll Mark D | Antiparasitical agents and methods for treating, preventing and controlling external parasites in animals |
| US8362086B2 (en) | 2005-08-19 | 2013-01-29 | Merial Limited | Long acting injectable formulations |
| BRPI0714194A2 (pt) * | 2006-07-05 | 2012-12-25 | Aventis Agriculture | compostos derivados de 1-aril-5-alquilpirazol, processos para fazÊ-los e mÉtodos para seus usos |
| ES2614931T3 (es) * | 2006-08-04 | 2017-06-02 | Beth Israel Deaconess Medical Center | Inhibidores de la piruvato cinasa y métodos de tratamiento de enfermedad |
| US9173728B2 (en) | 2008-11-19 | 2015-11-03 | Merial Inc. | Multi-cavity container having offset indentures for dispensing fluids |
| ES2781828T3 (es) | 2008-11-19 | 2020-09-08 | Boehringer Ingelheim Animal Health Usa Inc | Composiciones que comprenden un aril pirazol y/o una formamidina, procedimientos y usos de las mismas |
| CA2758071C (en) * | 2009-04-06 | 2018-01-09 | Agios Pharmaceuticals, Inc. | Pyruvate kinase m2 modulators, therapeutic compositions and related methods of use |
| EP2427441B1 (en) | 2009-05-04 | 2016-12-14 | Agios Pharmaceuticals, Inc. | Pkm2 activators for use in the treatment of cancer |
| TWI691493B (zh) | 2009-06-29 | 2020-04-21 | 美商阿吉歐斯製藥公司 | 治療化合物及組成物 |
| JP5764555B2 (ja) | 2009-06-29 | 2015-08-19 | アジオス ファーマシューティカルズ, インコーポレイテッド | 治療組成物および関連する使用方法 |
| US8980896B2 (en) | 2009-12-17 | 2015-03-17 | Merial, Inc. | Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles |
| UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
| US9221792B2 (en) | 2010-12-17 | 2015-12-29 | Agios Pharmaceuticals, Inc | N-(4-(azetidine-1-carbonyl) phenyl)-(hetero-) arylsulfonamide derivatives as pyruvate kinase M2 (PMK2) modulators |
| ES2569712T3 (es) | 2010-12-21 | 2016-05-12 | Agios Pharmaceuticals, Inc. | Activadores de PKM2 bicíclicos |
| TWI549947B (zh) | 2010-12-29 | 2016-09-21 | 阿吉歐斯製藥公司 | 治療化合物及組成物 |
| KR102024027B1 (ko) | 2011-05-03 | 2019-09-23 | 아지오스 파마슈티컬스 아이엔씨. | 치료에 사용하기 위한 피루베이트 키나아제 활성제 |
| US9181231B2 (en) | 2011-05-03 | 2015-11-10 | Agios Pharmaceuticals, Inc | Pyruvate kinase activators for use for increasing lifetime of the red blood cells and treating anemia |
| CA2855954C (en) | 2011-11-17 | 2020-09-01 | Merial Limited | Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof. |
| JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| TWI579274B (zh) | 2012-04-20 | 2017-04-21 | 龍馬躍公司 | 製備1-芳基-5-烷基吡唑化合物的改良方法 |
| WO2014139144A1 (en) | 2013-03-15 | 2014-09-18 | Agios Pharmaceuticals, Inc. | Therapeutic compounds and compositions |
| NZ731446A (en) | 2014-10-31 | 2018-09-28 | Boehringer Ingelheim Animal Health Usa Inc | Parasiticidal composition comprising fipronil |
| MA44392B1 (fr) | 2015-06-11 | 2023-10-31 | Agios Pharmaceuticals Inc | Procédés d'utilisation d'activateurs de la pyruvate kinase |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4048188A (en) * | 1971-12-07 | 1977-09-13 | The Boots Company Limited | 1-Carbonamido imidazoles |
| US3996366A (en) * | 1973-11-19 | 1976-12-07 | The Boots Company Limited | Thio derivatives of imidazol-1-yl carboxamides |
| GB1408877A (en) * | 1971-12-07 | 1975-10-08 | Boots Co Ltd | Substituted imidazoles and their use as pesticides |
| US3940484A (en) * | 1971-12-07 | 1976-02-24 | The Boots Company Limited | Insecticidal compositions and methods of combatting insects using substituted imidazoles |
| GB2044754B (en) * | 1978-11-14 | 1983-05-05 | Eisai Co Ltd | Imidazoles |
| US4600430A (en) * | 1985-02-22 | 1986-07-15 | Eli Lilly And Company | Pyridinylimidazolidinone compounds |
| US4634711A (en) * | 1985-08-02 | 1987-01-06 | Smithkline Beckman Corporation | Pyridylalkyl imidazole-2-thiols |
| DE3614364A1 (de) * | 1986-04-28 | 1987-10-29 | Hoechst Ag | 1-phenyl-imidazolverbindungen, verfahren zu ihrer herstellung und ihre verwendung als wachstumsregulatoren |
| CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
| FI91754C (fi) * | 1986-12-02 | 1994-08-10 | Tanabe Seiyaku Co | Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi |
| DE3811574A1 (de) * | 1988-03-31 | 1989-10-19 | Schering Ag | N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| CZ284824B6 (cs) * | 1989-05-05 | 1999-03-17 | Rhone-Poulenc Agrochimie | 1-Arylimidazoly, způsob jejich výroby a meziprodukty v tomto způsobu, prostředky, které je obsahují a jejich použití |
| MY106533A (en) * | 1990-02-20 | 1995-06-30 | Sumitomo Chemical Co | A 4-tert.-butyl imidazole derivative and its production and use. |
| CA2036148A1 (en) * | 1990-06-29 | 1991-12-30 | Hiroki Tomioka | A 1-phenylimidazole derivative and its production and use |
-
1991
- 1991-02-12 CA CA002036148A patent/CA2036148A1/en not_active Abandoned
- 1991-02-12 CA CA002036147A patent/CA2036147A1/en not_active Abandoned
- 1991-02-18 KR KR1019910002563A patent/KR920000745A/ko not_active Withdrawn
- 1991-02-18 KR KR1019910002564A patent/KR920000729A/ko not_active Withdrawn
- 1991-02-18 MY MYPI91000254A patent/MY104627A/en unknown
- 1991-02-18 MY MYPI91000253A patent/MY104626A/en unknown
- 1991-02-19 EP EP91301291A patent/EP0464980B1/en not_active Expired - Lifetime
- 1991-02-19 DE DE69103230T patent/DE69103230T2/de not_active Expired - Fee Related
- 1991-02-19 BR BR919100663A patent/BR9100663A/pt unknown
- 1991-02-19 HU HU91548A patent/HUT58058A/hu unknown
- 1991-02-19 ES ES91301290T patent/ES2057754T3/es not_active Expired - Lifetime
- 1991-02-19 EP EP91301290A patent/EP0464979B1/en not_active Expired - Lifetime
- 1991-02-19 BR BR919100662A patent/BR9100662A/pt unknown
- 1991-02-19 IL IL9727991A patent/IL97279A/en not_active IP Right Cessation
- 1991-02-19 IL IL97278A patent/IL97278A0/xx unknown
- 1991-02-19 DE DE69103231T patent/DE69103231T2/de not_active Expired - Fee Related
- 1991-02-19 ES ES91301291T patent/ES2057755T3/es not_active Expired - Lifetime
- 1991-02-19 HU HU91549A patent/HU206951B/hu not_active IP Right Cessation
- 1991-02-20 US US07/658,326 patent/US5153215A/en not_active Expired - Fee Related
- 1991-02-20 CZ CS91440A patent/CZ279536B6/cs unknown
- 1991-02-20 AU AU71188/91A patent/AU633184B2/en not_active Ceased
- 1991-02-20 AU AU71186/91A patent/AU633183B2/en not_active Ceased
- 1991-02-20 US US07/658,324 patent/US5122530A/en not_active Expired - Fee Related
- 1991-02-20 YU YU30391A patent/YU30391A/sh unknown
- 1991-02-20 YU YU30491A patent/YU30491A/sh unknown
- 1991-02-20 CZ CS91441A patent/CZ279634B6/cs unknown
- 1991-02-20 SK SK440-91A patent/SK278039B6/sk unknown
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