CS391391A3 - Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof - Google Patents

Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof Download PDF

Info

Publication number
CS391391A3
CS391391A3 CS913913A CS391391A CS391391A3 CS 391391 A3 CS391391 A3 CS 391391A3 CS 913913 A CS913913 A CS 913913A CS 391391 A CS391391 A CS 391391A CS 391391 A3 CS391391 A3 CS 391391A3
Authority
CS
Czechoslovakia
Prior art keywords
isomer
compound
formula
weight
optionally
Prior art date
Application number
CS913913A
Other languages
Czech (cs)
English (en)
Inventor
Erol Faruk
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of CS391391A3 publication Critical patent/CS391391A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
CS913913A 1983-03-24 1991-12-19 Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof CS391391A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838308062A GB8308062D0 (en) 1983-03-24 1983-03-24 Active compounds

Publications (1)

Publication Number Publication Date
CS391391A3 true CS391391A3 (en) 1992-09-16

Family

ID=10540102

Family Applications (1)

Application Number Title Priority Date Filing Date
CS913913A CS391391A3 (en) 1983-03-24 1991-12-19 Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof

Country Status (12)

Country Link
EP (1) EP0120428B1 (de)
JP (1) JPH0791188B2 (de)
AU (1) AU571498B2 (de)
CA (1) CA1284150C (de)
CS (1) CS391391A3 (de)
DE (1) DE3482323D1 (de)
ES (1) ES8607964A1 (de)
GB (1) GB8308062D0 (de)
GR (1) GR81923B (de)
IE (1) IE57119B1 (de)
NZ (1) NZ207594A (de)
ZA (1) ZA842123B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT84806B (pt) * 1986-05-03 1989-12-29 Beecham Group Plc Processo para a preparacao de benzopiranos
GB8625185D0 (en) * 1986-10-21 1986-11-26 Beecham Group Plc Active compounds
ES2058148T3 (es) * 1987-02-04 1994-11-01 Hoechst Ag N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.
DE3703227A1 (de) * 1987-02-04 1988-08-18 Hoechst Ag Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
CH674984A5 (de) * 1987-05-16 1990-08-15 Sandoz Ag
DE3811017A1 (de) * 1988-03-31 1989-10-19 Hoechst Ag Ungesaettigte n-benzopyranyllactame
DE3818245A1 (de) * 1988-05-28 1989-12-07 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
US4988723A (en) * 1988-06-02 1991-01-29 Fujisawa Pharmaceutical Co., Ltd. Benzopyran derivatives and their use as anti-hypertensives
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
DE3901720A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Substituierte benzo(b)pyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
GB8902118D0 (en) * 1989-02-01 1989-03-22 Beecham Group Plc Chemical process
US5239090A (en) * 1989-02-01 1993-08-24 Beecham Group P.L.C. Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates
US5066816A (en) * 1989-03-03 1991-11-19 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2h-1-benzopyran compounds and intermediates therefor
US5162553A (en) * 1989-03-03 1992-11-10 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor
IE63935B1 (en) * 1989-06-27 1995-06-28 Chem Pharm Forsch Gmbh Novel thienopyran derivatives a process for their preparation and their use
DE3922392A1 (de) 1989-07-07 1991-01-17 Merck Patent Gmbh Chromanderivate
HU207861B (en) * 1989-07-21 1993-06-28 Alkaloida Vegyeszeti Gyar Process for producing benzopirane derivative of blood pressure lowering activity
HUT72741A (en) * 1992-12-19 1996-05-28 Alkaloida Vegyeszeti Gyar Method for producing benzopyrane derivatives and pharmaceutical compositions containing them
AU4841700A (en) 1999-05-12 2000-11-21 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
EP3099304A4 (de) 2014-01-31 2018-01-10 Mayo Foundation for Medical Education and Research Neuartige therapeutika zur behandlung von glaukom

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1548222A (en) * 1976-12-17 1979-07-04 Beecham Group Ltd Trans-4-heterocyclyl-3,4-dihydro-2h-benzo pyarn-3-ol derivatives
DE2965739D1 (en) * 1978-10-04 1983-07-28 Beecham Group Plc Chromanol derivatives, a process for their preparation and pharmaceutical compositions comprising them
GB2064514B (en) * 1979-10-29 1984-01-18 Maruko Pharmaceutical Co Flavan compounds and acid addition salts thereof and pharmaceutical compositions thereof
DE3163018D1 (en) * 1980-02-02 1984-05-17 Beecham Group Plc Pyrano derivatives, a process for their preparation and antihypertensive compositions containing them
EP0076075B1 (de) * 1981-09-25 1986-11-20 Beecham Group Plc Benzopyran-Verbindungen mit pharmazeutischer Wirkung
JPH0471072A (ja) * 1990-07-11 1992-03-05 Fujitsu Ltd アナログ／ディジタル混載集積回路のシミュレーション方法

Also Published As

Publication number Publication date
DE3482323D1 (de) 1990-06-28
AU2600784A (en) 1984-09-27
ZA842123B (en) 1985-04-24
ES530958A0 (es) 1986-06-01
ES8607964A1 (es) 1986-06-01
JPH0791188B2 (ja) 1995-10-04
NZ207594A (en) 1987-07-31
EP0120428A1 (de) 1984-10-03
JPS59176282A (ja) 1984-10-05
IE57119B1 (en) 1992-05-06
AU571498B2 (en) 1988-04-21
EP0120428B1 (de) 1990-05-23
GR81923B (de) 1984-12-12
IE840707L (en) 1984-09-24
GB8308062D0 (en) 1983-05-05
CA1284150C (en) 1991-05-14

Similar Documents

Publication Publication Date Title
CS391391A3 (en) Benzopyran isomers, process of their preparation and pharmaceuticalscomprising thereof
US6017892A (en) Method for accelerating marrow cell proliferation
EP0370901B1 (de) Zentralnervensystem wirksame Chromanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen
EP0258755A1 (de) Alpha-alkyl-4-amino-3-chinolin-methanole und 1-(4-Aralkylamino-3-chinolyl)alkanone, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CA2083714A1 (en) Substituted benzimidazoles, process for their preparation and their pharmaceutical use
US5158970A (en) Proline derivatives
US4409146A (en) Substituted caprolactam derivatives as antihypertensives
EP0316279A2 (de) Veresterte azacyclische Hydroxyverbindungen
EP0546177B1 (de) Benzopyran derivat, seine darstellung und pharmazeutische zusammensetzung, welche dieses enthält
FR2621587A1 (fr) Derives du dimethyl-2,2 chromene, procede pour leur preparation et composition pharmaceutiques les contenant
EP0350878A2 (de) Konjugierte Oxybutenolide zur Behandlung von Ulcera
FR2467845A1 (fr) Nouveaux derives mercapto-acyles de prolines 4,4-disubstituees et de dehydroprolines 4-substituees, utiles notamment comme medicaments hypotenseurs, compositions therapeutiques et formes pharmaceutiques les contenant, et intermediaires utiles pour leur synthese
AU628995B2 (en) Novel thienopyran derivatives, a process for their preparation and their use
FR2549058A1 (fr) Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
EP1309557B9 (de) Amlodipin-hemimaleat
EP0405342B1 (de) (1,2,3,4-Tetrahydro-9-acridinimino)cyclohexan-Carbonsäure und verwandte Verbindungen, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Medikamente
EP0370902B1 (de) Verwendung von Chromanderivaten zur Herstellung eines Medikamentes zur Behandlung von depressiven Zuständen
EP0260605B1 (de) Dihydropyridin-5-phosphonsaure zyklische Ester
EP0124777B1 (de) Derivate des 1,4-Dihydropyridins
US4378369A (en) Esters of 2,5-anhydro-D-mannitol
KR950003499B1 (ko) 1,3,5-트리티안 유도체
EP0623608B1 (de) Benzopyran-derivate, deren herstellung sowie diese als aktive bestandteile enthaltende arzneimittel
AU595522B2 (en) Hydroquinolines and cerebral use thereof
WO1983003097A1 (en) 1,4-dihydropyridine derivatives, preparation thereof and pharmac eutical preparations containing them
KR850000844B1 (ko) 피롤리딘 유도체의 제조방법