CS325584A2 - Zpusob vyroby novych derivatu pyrimidonu - Google Patents
Zpusob vyroby novych derivatu pyrimidonuInfo
- Publication number
- CS325584A2 CS325584A2 CS843255A CS325584A CS325584A2 CS 325584 A2 CS325584 A2 CS 325584A2 CS 843255 A CS843255 A CS 843255A CS 325584 A CS325584 A CS 325584A CS 325584 A2 CS325584 A2 CS 325584A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- pyrimidonu
- derivatu
- zpusob vyroby
- novych
- vyroby novych
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH244283 | 1983-05-05 | ||
| CH139284 | 1984-03-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS325584A2 true CS325584A2 (en) | 1985-08-15 |
| CS243486B2 CS243486B2 (en) | 1986-06-12 |
Family
ID=25687524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS843255A CS243486B2 (en) | 1983-05-05 | 1984-05-02 | Method of new pyrimidine derivatives production |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4581172A (cs) |
| EP (1) | EP0124893A3 (cs) |
| AU (1) | AU2751084A (cs) |
| CA (1) | CA1237429A (cs) |
| CS (1) | CS243486B2 (cs) |
| DK (1) | DK198784A (cs) |
| ES (1) | ES532172A0 (cs) |
| FI (1) | FI841619A (cs) |
| HU (1) | HUT34025A (cs) |
| IL (1) | IL71711A (cs) |
| MC (1) | MC1600A1 (cs) |
| NO (1) | NO841780L (cs) |
| NZ (1) | NZ207981A (cs) |
| PH (1) | PH19219A (cs) |
| PT (1) | PT78549B (cs) |
| ZW (1) | ZW6284A1 (cs) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3472678D1 (de) * | 1983-07-18 | 1988-08-18 | Beecham Group Plc | Benzazepine and benzoxazepine derivatives |
| GB9707251D0 (en) * | 1997-04-10 | 1997-05-28 | Smithkline Beecham Plc | Novel method and compounds |
| CA2368413C (en) * | 1999-03-31 | 2008-07-29 | Vernalis Limited | Derivatives of pyrimido[6,1-a]isoquinolin-4-one |
| US7169907B2 (en) * | 2002-03-01 | 2007-01-30 | Roche Diagnostics Operations, Inc. | Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs |
| US7501512B2 (en) * | 2003-07-08 | 2009-03-10 | Smithkline Beecham Corporation | Chemical compounds |
| GB201502260D0 (en) | 2015-02-11 | 2015-04-01 | Verona Pharma Plc | Salt of Pyrimido[6,1-A]Isoquinolin-4-one compound |
| WO2017016960A1 (en) * | 2015-07-24 | 2017-02-02 | F. Hoffmann-La Roche Ag | Process for the preparation of (6s)-6-alkyl-10-alkoxy-9-(substituted alkoxy)-2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid analogues |
| GB201613054D0 (en) | 2016-07-28 | 2016-09-14 | Verona Pharma Plc | New compound and process |
| EP3822272A4 (en) * | 2018-07-13 | 2022-04-06 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | CONDENSED TRICYCLIC COMPOUND AS PDE3/PDE4 DOUBLE INHIBITOR |
| WO2021143841A1 (zh) * | 2020-01-15 | 2021-07-22 | 正大天晴药业集团股份有限公司 | 三并环类pde3/pde4双重抑制剂化合物的药物组合物 |
| WO2021143843A1 (zh) * | 2020-01-15 | 2021-07-22 | 正大天晴药业集团股份有限公司 | 一种pde3/pde4双重抑制剂的结晶及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2720085A1 (de) * | 1977-05-05 | 1978-11-16 | Hoechst Ag | Pyrimido(6,1-a)isochinolin-2-on- derivate |
| NZ185900A (en) * | 1976-12-10 | 1981-04-24 | Hoechst Ag | Pyrimido (6,1-a) isoquinolin-4-ones medicaments intermediate isoquinolines |
| FI64370C (fi) * | 1977-05-05 | 1983-11-10 | Hoechst Ag | Foerfarande foer framstaellning av terapeutiskt anvaendbara pyimido-(6,1-a)isokinolin-2-imino-4-onderivat |
| DE2847693A1 (de) * | 1978-11-03 | 1980-05-22 | Hoechst Ag | Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen |
| DE3135831A1 (de) * | 1981-09-10 | 1983-04-28 | Hoechst Ag, 6230 Frankfurt | 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1984
- 1984-04-13 CA CA000451949A patent/CA1237429A/en not_active Expired
- 1984-04-13 ZW ZW62/84A patent/ZW6284A1/xx unknown
- 1984-04-17 DK DK198784A patent/DK198784A/da not_active Application Discontinuation
- 1984-04-25 US US06/603,793 patent/US4581172A/en not_active Expired - Fee Related
- 1984-04-25 FI FI841619A patent/FI841619A/fi not_active Application Discontinuation
- 1984-04-27 NZ NZ207981A patent/NZ207981A/en unknown
- 1984-04-30 AU AU27510/84A patent/AU2751084A/en not_active Abandoned
- 1984-05-01 IL IL71711A patent/IL71711A/xx not_active IP Right Cessation
- 1984-05-02 CS CS843255A patent/CS243486B2/cs unknown
- 1984-05-02 HU HU841693A patent/HUT34025A/hu unknown
- 1984-05-02 MC MC841703A patent/MC1600A1/xx unknown
- 1984-05-04 PH PH30644A patent/PH19219A/en unknown
- 1984-05-04 PT PT78549A patent/PT78549B/pt unknown
- 1984-05-04 NO NO841780A patent/NO841780L/no unknown
- 1984-05-04 ES ES532172A patent/ES532172A0/es active Granted
- 1984-05-04 EP EP84105052A patent/EP0124893A3/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| MC1600A1 (fr) | 1985-05-09 |
| CS243486B2 (en) | 1986-06-12 |
| CA1237429A (en) | 1988-05-31 |
| PT78549B (en) | 1986-09-15 |
| DK198784D0 (da) | 1984-04-17 |
| US4581172A (en) | 1986-04-08 |
| NZ207981A (en) | 1987-05-29 |
| DK198784A (da) | 1984-11-06 |
| AU2751084A (en) | 1984-11-08 |
| ES8505369A1 (es) | 1985-06-01 |
| PH19219A (en) | 1986-02-12 |
| FI841619A (fi) | 1984-11-06 |
| IL71711A0 (en) | 1984-09-30 |
| ZW6284A1 (en) | 1985-10-30 |
| EP0124893A2 (de) | 1984-11-14 |
| FI841619A0 (fi) | 1984-04-25 |
| EP0124893A3 (de) | 1987-11-11 |
| NO841780L (no) | 1984-11-06 |
| PT78549A (en) | 1984-06-01 |
| ES532172A0 (es) | 1985-06-01 |
| HUT34025A (en) | 1985-01-28 |
| IL71711A (en) | 1987-08-31 |
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