CS274703B2 - Method of bu-3608 antibiotics' complex desxylosylderivatives production - Google Patents

Method of bu-3608 antibiotics' complex desxylosylderivatives production

Info

Publication number
CS274703B2
CS274703B2 CS71690A CS71690A CS274703B2 CS 274703 B2 CS274703 B2 CS 274703B2 CS 71690 A CS71690 A CS 71690A CS 71690 A CS71690 A CS 71690A CS 274703 B2 CS274703 B2 CS 274703B2
Authority
CS
Czechoslovakia
Prior art keywords
production
hydrogen
antibiotics
desxylosylderivatives
complex
Prior art date
Application number
CS71690A
Other languages
Czech (cs)
Other versions
CS71690A2 (en
Inventor
Maki Nishio
Masatoshi Kakushima
Masataka Konishi
Toshikazu Oki
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/221,144 external-priority patent/US4960755A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CS71690A2 publication Critical patent/CS71690A2/en
Publication of CS274703B2 publication Critical patent/CS274703B2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The solution concerns a method of production of compounds of general formula III, where R<1> is hydrogen and R<3> is hydrogen or methyl, or R<1> is methyl and R<3> is hydrogen and their pharmaceutically applicable salts. It is characteristic by the fact that from the compound of general formula II or its salt the β -D-xylosyl residuum is split out by heating in presence of mineral acid. The xylosyl residuum and the resulting product are eventually transformed to salt. The compounds produced in this way are used mainly as source substances for production of water-soluble antibiotics, while they show antifungal efficiency as well.<IMAGE>
CS71690A 1988-07-19 1989-07-19 Method of bu-3608 antibiotics' complex desxylosylderivatives production CS274703B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/221,144 US4960755A (en) 1988-07-19 1988-07-19 BU-3608 derivatives
CS440889A CS274700B2 (en) 1988-07-19 1989-07-19 Method of bu-3608 antibiotics' complex n-alkyl derivatives production

Publications (2)

Publication Number Publication Date
CS71690A2 CS71690A2 (en) 1990-11-14
CS274703B2 true CS274703B2 (en) 1991-09-15

Family

ID=25745992

Family Applications (1)

Application Number Title Priority Date Filing Date
CS71690A CS274703B2 (en) 1988-07-19 1989-07-19 Method of bu-3608 antibiotics' complex desxylosylderivatives production

Country Status (1)

Country Link
CS (1) CS274703B2 (en)

Also Published As

Publication number Publication date
CS71690A2 (en) 1990-11-14

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