CS270249B2 - Method of purine's new derivatives production - Google Patents
Method of purine's new derivatives production Download PDFInfo
- Publication number
- CS270249B2 CS270249B2 CS887057A CS705788A CS270249B2 CS 270249 B2 CS270249 B2 CS 270249B2 CS 887057 A CS887057 A CS 887057A CS 705788 A CS705788 A CS 705788A CS 270249 B2 CS270249 B2 CS 270249B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- purine
- formula
- fluoro
- amino
- threopentofuranosyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878725466A GB8725466D0 (en) | 1987-10-30 | 1987-10-30 | Purine derivatives |
| GB888816612A GB8816612D0 (en) | 1987-10-30 | 1988-06-13 | Purine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS705788A2 CS705788A2 (en) | 1989-10-13 |
| CS270249B2 true CS270249B2 (en) | 1990-06-13 |
Family
ID=26292971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS887057A CS270249B2 (en) | 1987-10-30 | 1988-10-25 | Method of purine's new derivatives production |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0314011A3 (zh) |
| JP (1) | JPH01149797A (zh) |
| CN (1) | CN1038102A (zh) |
| AU (1) | AU2416088A (zh) |
| CS (1) | CS270249B2 (zh) |
| DK (1) | DK603788A (zh) |
| FI (1) | FI884954A (zh) |
| HU (1) | HU199502B (zh) |
| IL (1) | IL88138A0 (zh) |
| MC (1) | MC1984A1 (zh) |
| NO (1) | NO168037C (zh) |
| NZ (1) | NZ226672A (zh) |
| PH (1) | PH25577A (zh) |
| PT (1) | PT88891B (zh) |
| YU (1) | YU199688A (zh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310732A (en) * | 1986-02-03 | 1994-05-10 | The Scripps Research Institute | 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis |
| US5106837A (en) * | 1988-03-16 | 1992-04-21 | The Scripps Research Institute | Adenosine derivatives with therapeutic activity |
| US4908440A (en) * | 1987-11-12 | 1990-03-13 | Bristol Myers Company | 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides |
| US4997926A (en) * | 1987-11-18 | 1991-03-05 | Scripps Clinic And Research Foundation | Deaminase-stable anti-retroviral 2-halo-2',3'-dideoxy |
| CA1339964C (en) * | 1988-03-16 | 1998-07-21 | Dennis A. Carson | Substituted adenine derivatives useful as therapeutic agents |
| NZ232912A (en) * | 1989-03-17 | 1992-06-25 | Oncogen Ltd Lp | Synergistic composition of nucleoside derivatives for inhibiting hiv |
| US5034518A (en) * | 1989-05-23 | 1991-07-23 | Southern Research Institute | 2-fluoro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl) adenine nucleosides |
| US5384310A (en) * | 1989-05-23 | 1995-01-24 | Southern Research Institute | 2'-fluoro-2-haloarabinoadinosines and their pharmaceutical compositions |
| HU906976D0 (en) * | 1989-11-13 | 1991-05-28 | Bristol Myers Squibb Co | Process for producing 2', 3'-didesoxy-2'-fluoarabinonucleoside analogues |
| DK1261350T3 (da) * | 2000-02-18 | 2006-11-13 | Southern Res Inst | Fremgangsmåder til syntetisering af 2-chlor-9-(2-deoxy-2-fluor-beta-d-arabinofuranosyl)-9H-purin-6-amin |
| US6753322B2 (en) | 2000-06-06 | 2004-06-22 | Pfizer Inc | 2-aminocarbonyl-9H-purine derivatives |
| US7528247B2 (en) | 2001-08-02 | 2009-05-05 | Genzyme Corporation | Process for preparing purine nucleosides |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340645C (en) * | 1987-04-17 | 1999-07-13 | Victor E. Marquez | Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus |
-
1988
- 1988-10-21 NZ NZ226672A patent/NZ226672A/en unknown
- 1988-10-21 EP EP88117572A patent/EP0314011A3/de not_active Withdrawn
- 1988-10-24 AU AU24160/88A patent/AU2416088A/en not_active Abandoned
- 1988-10-24 IL IL8888138A patent/IL88138A0/xx unknown
- 1988-10-25 CS CS887057A patent/CS270249B2/cs unknown
- 1988-10-26 YU YU01996/88A patent/YU199688A/xx unknown
- 1988-10-26 HU HU885588A patent/HU199502B/hu unknown
- 1988-10-27 FI FI884954A patent/FI884954A/fi not_active Application Discontinuation
- 1988-10-27 MC MC882013A patent/MC1984A1/xx unknown
- 1988-10-27 PH PH37735A patent/PH25577A/en unknown
- 1988-10-28 PT PT88891A patent/PT88891B/pt not_active IP Right Cessation
- 1988-10-28 NO NO88884830A patent/NO168037C/no unknown
- 1988-10-28 JP JP63271119A patent/JPH01149797A/ja active Pending
- 1988-10-28 DK DK603788A patent/DK603788A/da not_active Application Discontinuation
- 1988-10-28 CN CN88107516A patent/CN1038102A/zh active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU2416088A (en) | 1989-05-04 |
| NO168037B (no) | 1991-09-30 |
| EP0314011A2 (de) | 1989-05-03 |
| NO168037C (no) | 1992-01-08 |
| PH25577A (en) | 1991-08-08 |
| PT88891B (pt) | 1993-01-29 |
| FI884954A0 (fi) | 1988-10-27 |
| FI884954A (fi) | 1989-05-01 |
| DK603788A (da) | 1989-05-01 |
| JPH01149797A (ja) | 1989-06-12 |
| DK603788D0 (da) | 1988-10-28 |
| NO884830D0 (no) | 1988-10-28 |
| CN1038102A (zh) | 1989-12-20 |
| HUT48270A (en) | 1989-05-29 |
| IL88138A0 (en) | 1989-06-30 |
| NO884830L (no) | 1989-05-02 |
| EP0314011A3 (de) | 1990-04-11 |
| NZ226672A (en) | 1991-07-26 |
| CS705788A2 (en) | 1989-10-13 |
| YU199688A (en) | 1990-04-30 |
| HU199502B (en) | 1990-02-28 |
| MC1984A1 (fr) | 1989-11-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3587500T2 (de) | Tumorbehandlung bei Säugetieren. | |
| US5583239A (en) | Antimicrobial sterol conjugates | |
| FI63946B (fi) | Foerfarande foer framstaellning av terapeutiskt anvaendbara 5'deoxi-5-fluorcytidin och 5'-deoxi-5-fluor-uridin | |
| FR2709754A1 (fr) | Composés 2' ou 3'-déoxy- et 2', 3'-didéoxy-beta-L-pentofuranonucléosides, procédé de préparation et application thérapeutique, notamment anti-virale. | |
| CS270249B2 (en) | Method of purine's new derivatives production | |
| AU602083B2 (en) | Pyrimidine derivatives | |
| US4882316A (en) | Pyrimidine derivatives | |
| GB2073752A (en) | 2,6-diaminobularines | |
| US5441932A (en) | Sugar compounds for inhibition of the biosynthesis of sugar chains containing sialic acid | |
| US4258033A (en) | 2,6-Diaminonebularines | |
| US3948885A (en) | 5-Hydroxyl-1,2,3-triazole-4-carboxamide nucleoside | |
| FR2499577A1 (fr) | Nouvelles 1-(2-chloroethyl)-1-nitrosourees-3-substituees par un reste de sucre, utiles notamment comme agents antitumoraux et leur procede de preparation | |
| WO1995018817A1 (fr) | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant | |
| US4794115A (en) | Method of treating hyperlipemia | |
| US4554349A (en) | Aralkyl and aralkenyl glycosides as inhibitors of antigen-specific T-cell proliferation | |
| JPH0267295A (ja) | プリン誘導体 | |
| JPS632279B2 (zh) | ||
| US4423073A (en) | Fluorinated diaminopentene derivatives | |
| CS203946B2 (en) | Method of producing n1-glucofuranosid-6-yl-n 3-nitrosoureas | |
| WO2008007027A1 (fr) | Nouveaux derives de 5-thioxylopyranose | |
| EP0060099A1 (en) | Antiviral agents, their preparation and use | |
| KR820001541B1 (ko) | 치환 몰라노린 유도체의 제조방법 | |
| JPH05148292A (ja) | ６−ｏ−アルキルエルサマイシンａ誘導体の製造法 | |
| FR2487359A1 (fr) | 11a-amino-androstanes, leur preparation et compositions en contenant | |
| JPH05163292A (ja) | ３’及び／又は４’位の水酸基を化学修飾したエルサマイシンａ誘導体の製造法 |