CS221974B2 - Method of preparation of / / enanciomere,mixture // and/-/ enanciomere or/-/ racemate derivative of the hexahydro-trans-4a, 9b-1 /h/ pyridoindole - Google Patents

Method of preparation of / / enanciomere,mixture // and/-/ enanciomere or/-/ racemate derivative of the hexahydro-trans-4a, 9b-1 /h/ pyridoindole

Info

Publication number
CS221974B2
CS221974B2 CS805260A CS526080A CS221974B2 CS 221974 B2 CS221974 B2 CS 221974B2 CS 805260 A CS805260 A CS 805260A CS 526080 A CS526080 A CS 526080A CS 221974 B2 CS221974 B2 CS 221974B2
Authority
CS
Czechoslovakia
Prior art keywords
enanciomere
pyridoindole
racemate
hexahydro
trans
Prior art date
Application number
CS805260A
Other languages
Czech (cs)
English (en)
Inventor
Willard Welch
Charles A Harbert
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CS221974B2 publication Critical patent/CS221974B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CS805260A 1979-07-30 1980-07-25 Method of preparation of / / enanciomere,mixture // and/-/ enanciomere or/-/ racemate derivative of the hexahydro-trans-4a, 9b-1 /h/ pyridoindole CS221974B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/061,573 US4252811A (en) 1979-07-30 1979-07-30 Hexahydro-trans-pyridoindole neuroleptic agents

Publications (1)

Publication Number Publication Date
CS221974B2 true CS221974B2 (en) 1983-04-29

Family

ID=22036658

Family Applications (1)

Application Number Title Priority Date Filing Date
CS805260A CS221974B2 (en) 1979-07-30 1980-07-25 Method of preparation of / / enanciomere,mixture // and/-/ enanciomere or/-/ racemate derivative of the hexahydro-trans-4a, 9b-1 /h/ pyridoindole

Country Status (33)

Country Link
US (1) US4252811A (xx)
JP (1) JPS5626891A (xx)
KR (1) KR840000914B1 (xx)
AR (1) AR226314A1 (xx)
AT (1) AT375659B (xx)
AU (1) AU513948B2 (xx)
BE (1) BE884530A (xx)
CA (1) CA1133483A (xx)
CH (1) CH644379A5 (xx)
CS (1) CS221974B2 (xx)
DD (1) DD153691A5 (xx)
DE (1) DE3028555A1 (xx)
DK (1) DK148140C (xx)
EG (1) EG14903A (xx)
ES (1) ES493818A0 (xx)
FI (1) FI68828C (xx)
FR (1) FR2463140A1 (xx)
GB (1) GB2055372B (xx)
GR (1) GR69664B (xx)
IE (1) IE50035B1 (xx)
IL (1) IL60695A (xx)
IT (1) IT1194815B (xx)
LU (1) LU82662A1 (xx)
NL (1) NL180216C (xx)
NO (1) NO153729C (xx)
NZ (1) NZ194467A (xx)
PH (1) PH22657A (xx)
PL (1) PL133456B1 (xx)
PT (1) PT71623B (xx)
SE (1) SE438505B (xx)
SU (1) SU1172450A3 (xx)
YU (1) YU42223B (xx)
ZA (1) ZA804604B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4748247A (en) * 1986-10-21 1988-05-31 American Home Products Corporation 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]alkyl]alkyl]pyrido- and pyrazino-indole-1,3-dione derivatives as histamine H1 antagonists
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
JPH05101365A (ja) * 1991-03-22 1993-04-23 Tdk Corp 垂直磁気記録媒体およびその製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687961A (en) * 1971-05-03 1972-08-29 Abbott Lab 8-fluoro-2-{8 3-(4-fluorophenylanilinopropyl{9 -gamma-carboline
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (xx) * 1974-03-20 1975-10-04
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
SE7702301L (sv) * 1976-04-08 1977-10-09 Endo Lab Trans-hexahydro-pyrido-indoler

Also Published As

Publication number Publication date
DK148140B (da) 1985-03-18
FR2463140A1 (fr) 1981-02-20
CH644379A5 (fr) 1984-07-31
NL180216C (nl) 1987-01-16
AT375659B (de) 1984-08-27
IL60695A0 (en) 1980-09-16
ATA393280A (de) 1984-01-15
BE884530A (fr) 1981-01-29
JPS6357433B2 (xx) 1988-11-11
AU513948B2 (en) 1981-01-15
IE801576L (en) 1981-01-30
NO153729C (no) 1986-05-14
EG14903A (en) 1985-12-31
SU1172450A3 (ru) 1985-08-07
NL8004332A (nl) 1981-02-03
NO802274L (no) 1981-02-02
YU191780A (en) 1983-12-31
FR2463140B1 (xx) 1983-07-22
IE50035B1 (en) 1986-02-05
SE8005453L (sv) 1981-01-31
KR840000914B1 (ko) 1984-06-28
NO153729B (no) 1986-02-03
FI68828C (fi) 1985-11-11
PL225940A1 (xx) 1982-11-08
ES8105732A1 (es) 1981-05-16
LU82662A1 (fr) 1981-03-24
PH22657A (en) 1988-10-28
FI802371A (fi) 1981-01-31
US4252811A (en) 1981-02-24
CA1133483A (en) 1982-10-12
DK260080A (da) 1981-01-31
GB2055372B (en) 1983-05-05
NZ194467A (en) 1984-05-31
PT71623A (en) 1980-08-01
FI68828B (fi) 1985-07-31
IT8023785A0 (it) 1980-07-29
PT71623B (en) 1982-06-09
DK148140C (da) 1985-09-16
PL133456B1 (en) 1985-06-29
AR226314A1 (es) 1982-06-30
NL180216B (nl) 1986-08-18
KR830003480A (ko) 1983-06-20
JPS5626891A (en) 1981-03-16
ZA804604B (en) 1981-07-29
ES493818A0 (es) 1981-05-16
IL60695A (en) 1983-11-30
GR69664B (xx) 1982-07-07
YU42223B (en) 1988-06-30
SE438505B (sv) 1985-04-22
IT1194815B (it) 1988-09-28
DE3028555A1 (de) 1981-02-12
GB2055372A (en) 1981-03-04
DD153691A5 (de) 1982-01-27

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