CS192506B2 - Method for the separation of cephalosporins c - Google Patents

Method for the separation of cephalosporins c

Info

Publication number
CS192506B2
CS192506B2 CS737751A CS775173A CS192506B2 CS 192506 B2 CS192506 B2 CS 192506B2 CS 737751 A CS737751 A CS 737751A CS 775173 A CS775173 A CS 775173A CS 192506 B2 CS192506 B2 CS 192506B2
Authority
CS
Czechoslovakia
Prior art keywords
cephalosporins
separation
Prior art date
Application number
CS737751A
Other languages
English (en)
Inventor
Billy G Jackson
Martha C Stamper
Edmond M Bottorff
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00306130A external-priority patent/US3843642A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS192506B2 publication Critical patent/CS192506B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/12Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CS737751A 1972-11-13 1973-11-12 Method for the separation of cephalosporins c CS192506B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US00306130A US3843642A (en) 1972-11-13 1972-11-13 Cephalosporin c derivatives
US00398725A US3853863A (en) 1972-11-13 1973-09-19 Cephalosporin c isolation process

Publications (1)

Publication Number Publication Date
CS192506B2 true CS192506B2 (en) 1979-08-31

Family

ID=26974991

Family Applications (1)

Application Number Title Priority Date Filing Date
CS737751A CS192506B2 (en) 1972-11-13 1973-11-12 Method for the separation of cephalosporins c

Country Status (24)

Country Link
US (1) US3853863A (cs)
JP (1) JPS5721318B2 (cs)
KR (1) KR780000012B1 (cs)
AR (1) AR202466A1 (cs)
AT (1) AT327386B (cs)
AU (1) AU471843B2 (cs)
CA (1) CA1016163A (cs)
CH (1) CH599224A5 (cs)
CS (1) CS192506B2 (cs)
DD (1) DD112653A5 (cs)
DE (1) DE2356122C2 (cs)
ES (1) ES420336A1 (cs)
FR (1) FR2207140B1 (cs)
GB (1) GB1444575A (cs)
HU (1) HU167596B (cs)
IE (1) IE38382B1 (cs)
IL (1) IL43560A (cs)
NL (1) NL180106C (cs)
PH (1) PH9509A (cs)
PL (1) PL91577B1 (cs)
RO (1) RO63260A (cs)
SE (1) SE409713B (cs)
SU (1) SU603343A3 (cs)
YU (1) YU283173A (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2458554A1 (de) * 1974-01-03 1975-07-10 Lepetit Spa Neues verfahren fuer die gewinnung von cephalosporin c aus einer fermentationsbruehe
GB1489231A (en) * 1974-02-20 1977-10-19 Alfa Farmaceutici Spa Process for the recovery of cephalosporin c and derivatives thereof
JPS557438B2 (cs) * 1974-02-22 1980-02-25
US4168268A (en) * 1977-03-01 1979-09-18 Merck & Co., Inc. Process for isolating thienamycin
US4137405A (en) * 1977-07-28 1979-01-30 Merck & Co., Inc. Isolation of antibiotic Cephamycin C
FR2404642A1 (fr) * 1977-09-29 1979-04-27 Roussel Uclaf Nouveau derive de la cephalosporine c, procede de preparation et application du nouveau produit a la preparation de l'acide 7-amino cephalosporanique
AT367060B (de) * 1979-01-25 1982-05-25 Biochemie Gmbh Verfahren zur herstellung neuer cephalosporinderivate
JPS58143751A (ja) * 1982-02-19 1983-08-26 日本電熱株式会社 排便装置付ベツト
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3227709A (en) * 1961-11-28 1966-01-04 Merck & Co Inc Derivatives of cephalosporin c and process
US3234222A (en) * 1962-02-16 1966-02-08 Ciba Geigy Corp Preparation of 7-acylaminocephalosporanic acids
CH481142A (de) * 1966-12-05 1969-11-15 Ciba Geigy Verfahren zur Isolierung von Cephalosporin C
GB1311268A (en) * 1971-01-26 1973-03-28 Pfizer Process for the isolation of n-benzoyl cephalosporin c

Also Published As

Publication number Publication date
FR2207140B1 (cs) 1977-06-03
CH599224A5 (cs) 1978-05-12
YU283173A (en) 1982-02-28
DD112653A5 (cs) 1975-04-20
NL7315480A (cs) 1974-05-15
NL180106B (nl) 1986-08-01
CA1016163A (en) 1977-08-23
IL43560A (en) 1976-09-30
IE38382L (en) 1974-05-13
RO63260A (fr) 1978-06-15
IL43560A0 (en) 1974-03-14
US3853863A (en) 1974-12-10
DE2356122A1 (de) 1974-05-22
AU6155573A (en) 1975-04-24
AT327386B (de) 1976-01-26
SE409713B (sv) 1979-09-03
AR202466A1 (es) 1975-06-13
ES420336A1 (es) 1976-06-16
GB1444575A (en) 1976-08-04
HU167596B (cs) 1975-11-28
NL180106C (nl) 1987-01-02
PL91577B1 (cs) 1977-03-31
JPS5721318B2 (cs) 1982-05-06
FR2207140A1 (cs) 1974-06-14
IE38382B1 (en) 1978-03-01
PH9509A (en) 1976-01-09
JPS49133595A (cs) 1974-12-21
AU471843B2 (en) 1976-05-06
SU603343A3 (ru) 1978-04-15
ATA954273A (de) 1975-04-15
KR780000012B1 (en) 1978-03-04
DE2356122C2 (de) 1983-12-22

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