CS190723B1 - 2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same - Google Patents

2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same

Info

Publication number
CS190723B1
CS190723B1 CS764324A CS432476A CS190723B1 CS 190723 B1 CS190723 B1 CS 190723B1 CS 764324 A CS764324 A CS 764324A CS 432476 A CS432476 A CS 432476A CS 190723 B1 CS190723 B1 CS 190723B1
Authority
CS
Czechoslovakia
Prior art keywords
carboxyethylester
chlorbenzoyl
methoxy
phenyl
methyl
Prior art date
Application number
CS764324A
Other languages
Czech (cs)
English (en)
Inventor
Ludmila Fisnerova
Jaroslava Grimova
Zdenek Roubal
Oldrich Nemecek
Original Assignee
Ludmila Fisnerova
Jaroslava Grimova
Zdenek Roubal
Oldrich Nemecek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludmila Fisnerova, Jaroslava Grimova, Zdenek Roubal, Oldrich Nemecek filed Critical Ludmila Fisnerova
Priority to CS764324A priority Critical patent/CS190723B1/cs
Priority to GB22716/77A priority patent/GB1523088A/en
Priority to BE178406A priority patent/BE855644A/xx
Priority to DE2727629A priority patent/DE2727629C2/de
Priority to JP7621377A priority patent/JPS5318564A/ja
Priority to CH800277A priority patent/CH638494A5/de
Priority to FR7720144A priority patent/FR2356637A1/fr
Priority to US05/811,881 priority patent/US4136194A/en
Publication of CS190723B1 publication Critical patent/CS190723B1/cs
Priority to CS766687A priority patent/CS264470B3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS764324A 1976-06-30 1976-06-30 2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same CS190723B1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CS764324A CS190723B1 (en) 1976-06-30 1976-06-30 2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same
GB22716/77A GB1523088A (en) 1976-06-30 1977-05-30 2 - phenyl - 2 - carboxyethyl 1 - (p - chlorobenzoyl) - 5-methoxy - 2 - methyl - 3 - indolylacetate and process for the preparation thereof
BE178406A BE855644A (fr) 1976-06-30 1977-06-13 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetate de 2-phenyl-2-carboxyethyle et son procede de preparation
DE2727629A DE2727629C2 (de) 1976-06-30 1977-06-20 1-p-Chlorbenzoyl-5-methoxy-2-methyl- 3-indolyl-essigsäure-2'-phenyl-2'-carbonsäureäthylester, Verfahren zu seiner Herstellung und pharmazeutische Mittel
JP7621377A JPS5318564A (en) 1976-06-30 1977-06-28 22phenyll22carboxyethyl 11*ppchlorobenzoyl** 55methoxyy22mthyll33indolylacetate* its preparation and antiinflammatory agent
CH800277A CH638494A5 (de) 1976-06-30 1977-06-29 Verfahren zur herstellung von 1-(p-chlorbenzoyl)-5-methoxy-2-methyl-3-indolylessigsaeure-2'-phenyl-2'-carboxyaethylester.
FR7720144A FR2356637A1 (fr) 1976-06-30 1977-06-30 2-phenyl-2-carboxyethyl 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetate, et procede de preparation de ce produit presentant une activite anti-inflammatoire
US05/811,881 US4136194A (en) 1976-06-30 1977-06-30 2-phenyl-2-carboxyethyl 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetate and process for preparation thereof
CS766687A CS264470B3 (en) 1976-06-30 1987-10-26 Process for preparing esters of indomethacine with tropic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS764324A CS190723B1 (en) 1976-06-30 1976-06-30 2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same

Publications (1)

Publication Number Publication Date
CS190723B1 true CS190723B1 (en) 1979-06-29

Family

ID=5385718

Family Applications (1)

Application Number Title Priority Date Filing Date
CS764324A CS190723B1 (en) 1976-06-30 1976-06-30 2-phenyl-2-carboxyethylester of 1-/p-chlorbenzoyl/-5-methoxy-2-methyl-3-indolyl acetic acid and method of producing the same

Country Status (8)

Country Link
US (1) US4136194A (ja)
JP (1) JPS5318564A (ja)
BE (1) BE855644A (ja)
CH (1) CH638494A5 (ja)
CS (1) CS190723B1 (ja)
DE (1) DE2727629C2 (ja)
FR (1) FR2356637A1 (ja)
GB (1) GB1523088A (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5872560A (ja) * 1981-10-27 1983-04-30 Teikoku Chem Ind Corp Ltd インドメタシンフエニルエステル誘導体
DE3206887A1 (de) * 1982-02-26 1983-09-15 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure
DE3206889A1 (de) * 1982-02-26 1983-09-15 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure
JPS63111965U (ja) * 1987-01-12 1988-07-19
DE20205419U1 (de) 2002-04-08 2002-06-27 Burgmann Dichtungswerke Gmbh Gleitring-Dichtungsanordnung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2234651C3 (de) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen
DE2413125C2 (de) * 1974-03-15 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Indolylacetylaminosäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneipräparate

Also Published As

Publication number Publication date
FR2356637A1 (fr) 1978-01-27
FR2356637B1 (ja) 1980-02-08
JPS6137264B2 (ja) 1986-08-22
DE2727629A1 (de) 1978-01-12
US4136194A (en) 1979-01-23
BE855644A (fr) 1977-10-03
JPS5318564A (en) 1978-02-20
GB1523088A (en) 1978-08-31
CH638494A5 (de) 1983-09-30
DE2727629C2 (de) 1986-09-25

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