CS190478B2 - Method of producing novel biphenylyl derivatives - Google Patents

Method of producing novel biphenylyl derivatives

Info

Publication number
CS190478B2
CS190478B2 CS753282A CS328275A CS190478B2 CS 190478 B2 CS190478 B2 CS 190478B2 CS 753282 A CS753282 A CS 753282A CS 328275 A CS328275 A CS 328275A CS 190478 B2 CS190478 B2 CS 190478B2
Authority
CS
Czechoslovakia
Prior art keywords
producing novel
biphenylyl
derivatives
biphenylyl derivatives
novel
Prior art date
Application number
CS753282A
Other languages
Czech (cs)
English (en)
Inventor
Josef Nickl
Erich Mueller
Berthold Narr
Walter Haarmann
Wolfgang Schroeter
Rudolf Kadatz
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2424475A external-priority patent/DE2424475C3/de
Priority claimed from DE19752500944 external-priority patent/DE2500944A1/de
Priority claimed from DE19752503770 external-priority patent/DE2503770A1/de
Priority claimed from DE19752508244 external-priority patent/DE2508244A1/de
Priority claimed from DE19752508243 external-priority patent/DE2508243A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CS190478B2 publication Critical patent/CS190478B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/02Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
    • C07C317/10Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/16Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/24Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/16Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/45Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms doubly-bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/65Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfone or sulfoxide groups bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
CS753282A 1974-05-20 1975-05-12 Method of producing novel biphenylyl derivatives CS190478B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE2424475A DE2424475C3 (de) 1974-05-20 1974-05-20 Neue Biphenylsulfoxide, deren Diastereomere und optisch aktive Antipoden
DE19752500944 DE2500944A1 (de) 1974-05-20 1975-01-11 Neue sulfoxide
DE19752503770 DE2503770A1 (de) 1974-05-20 1975-01-30 Neue sulfoxide
DE19752508244 DE2508244A1 (de) 1974-05-20 1975-02-26 Neue sulfone
DE19752508243 DE2508243A1 (de) 1974-05-20 1975-02-26 Neue sulfoxide

Publications (1)

Publication Number Publication Date
CS190478B2 true CS190478B2 (en) 1979-05-31

Family

ID=27510355

Family Applications (1)

Application Number Title Priority Date Filing Date
CS753282A CS190478B2 (en) 1974-05-20 1975-05-12 Method of producing novel biphenylyl derivatives

Country Status (20)

Country Link
US (2) US3993683A (US06811534-20041102-M00003.png)
JP (1) JPS50160243A (US06811534-20041102-M00003.png)
AT (4) AT336589B (US06811534-20041102-M00003.png)
BE (1) BE829256A (US06811534-20041102-M00003.png)
CA (1) CA1064032A (US06811534-20041102-M00003.png)
CS (1) CS190478B2 (US06811534-20041102-M00003.png)
DD (1) DD119783A5 (US06811534-20041102-M00003.png)
DK (1) DK217375A (US06811534-20041102-M00003.png)
FI (1) FI751334A (US06811534-20041102-M00003.png)
FR (1) FR2271810B1 (US06811534-20041102-M00003.png)
GB (1) GB1469083A (US06811534-20041102-M00003.png)
HU (1) HU170754B (US06811534-20041102-M00003.png)
IE (1) IE41149B1 (US06811534-20041102-M00003.png)
IL (1) IL47314A (US06811534-20041102-M00003.png)
LU (1) LU72534A1 (US06811534-20041102-M00003.png)
NL (1) NL7505878A (US06811534-20041102-M00003.png)
NO (1) NO141013C (US06811534-20041102-M00003.png)
PL (1) PL100910B1 (US06811534-20041102-M00003.png)
RO (1) RO73127A (US06811534-20041102-M00003.png)
SE (1) SE7505749L (US06811534-20041102-M00003.png)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2546319C2 (de) * 1975-10-16 1986-02-27 Dr. Karl Thomae Gmbh, 7950 Biberach Cyclohexylphenyl-Derivate, Verfahren zu deren Herstellung und diese enthaltende Mittel
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
JPS54129687U (US06811534-20041102-M00003.png) * 1978-02-15 1979-09-08
FR2528041A1 (fr) * 1982-06-04 1983-12-09 Lafon Labor Acides halogenobenzhydrylsulfinylacetohydroxamiques, procede de preparation et utilisation en therapeutique
GB8311678D0 (en) * 1983-04-28 1983-06-02 Ici Plc Phenol derivatives
DE3332692A1 (de) * 1983-09-10 1985-03-28 Merck Patent Gmbh, 6100 Darmstadt Anisotrope verbindungen und fluessigkristallmischungen
US5252252A (en) * 1983-09-10 1993-10-12 Merck Patent Gesellschaft Mit Beschraenkter Haftung Anisotropic compounds and liquid crystal mixtures
IE58417B1 (en) * 1984-04-27 1993-09-22 Ici Plc Chemical derivatives
DE3724735A1 (de) * 1987-07-25 1989-02-02 Hoechst Ag Leukotrienantagonisten, verfahren zu ihrer herstellung, ihre anwendung zur behandlung von krankheiten, sowie vorprodukte
DE3724669A1 (de) * 1987-07-25 1989-02-02 Hoechst Ag Leukotrienantagonisten, verfahren zu ihrer herstellung und ihre anwendung zur behandlung von krankheiten
US5256692A (en) * 1992-01-07 1993-10-26 E. R. Squibb & Sons, Inc. Sulfur-containing HMG-COA reductase inhibitors
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
AR002945A1 (es) * 1994-11-15 1998-05-27 Bayer Corp Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos
US5856340A (en) * 1995-02-28 1999-01-05 Eli Lilly And Company Method of treating estrogen dependent cancers
US5856339A (en) * 1995-02-28 1999-01-05 Eli Lilly And Company Benzothiophene compounds, intermediates, compositions, and methods
KR100809489B1 (ko) * 2001-10-10 2008-03-03 씨제이제일제당 (주) 사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난4'-메탄설포닐-비페닐 유도체
US20060276539A1 (en) * 2002-10-16 2006-12-07 Dalton James T Treating Androgen Decline in Aging Male (ADAM)- associated conditions with SARMS
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
EP1586559A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Biaryl-methanethio-, -sulphinyl- and sulphonyl derivatives
CA2587566A1 (en) * 2004-11-18 2006-05-26 The Institutes For Pharmaceutical Discovery, Llc Heterocyclylbiphenyl derivates as protein tyrosine phosphatase inhibitors
EP1893570A4 (en) * 2005-06-22 2009-12-23 Reddy Manne Satynarayana IMPROVED PROCESS FOR THE PREPARATION OF EZETIMIBE
US8818322B2 (en) * 2006-06-09 2014-08-26 Trapeze Networks, Inc. Untethered access point mesh system and method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
GB1121027A (en) * 1966-06-23 1968-07-24 Ici Ltd New carboxylic acid derivatives, processes for the preparation thereof and compositions containing the same
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives

Also Published As

Publication number Publication date
US3993683A (en) 1976-11-23
NO751358L (US06811534-20041102-M00003.png) 1975-11-21
SE7505749L (sv) 1975-11-21
ATA515877A (de) 1978-04-15
GB1469083A (en) 1977-03-30
IL47314A0 (en) 1975-07-28
FI751334A (US06811534-20041102-M00003.png) 1975-11-21
FR2271810B1 (US06811534-20041102-M00003.png) 1979-08-10
ATA267375A (de) 1976-09-15
NL7505878A (nl) 1975-11-24
JPS50160243A (US06811534-20041102-M00003.png) 1975-12-25
ATA515777A (de) 1978-04-15
ATA434976A (de) 1977-11-15
AT344149B (de) 1978-07-10
IL47314A (en) 1979-05-31
FR2271810A1 (US06811534-20041102-M00003.png) 1975-12-19
LU72534A1 (US06811534-20041102-M00003.png) 1977-02-10
US4191776A (en) 1980-03-04
AT346833B (de) 1978-11-27
AT336589B (de) 1977-05-10
RO73127A (ro) 1981-11-04
IE41149B1 (en) 1979-10-24
DK217375A (da) 1975-11-21
DD119783A5 (US06811534-20041102-M00003.png) 1976-05-12
HU170754B (US06811534-20041102-M00003.png) 1977-08-28
NO141013B (no) 1979-09-17
BE829256A (fr) 1975-11-20
CA1064032A (en) 1979-10-09
IE41149L (en) 1975-11-20
NO141013C (no) 1979-12-27
AT346834B (de) 1978-11-27
PL100910B1 (pl) 1978-11-30

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