CS161826B2 - - Google Patents

Info

Publication number
CS161826B2
CS161826B2 CS1762A CS176259A CS161826B2 CS 161826 B2 CS161826 B2 CS 161826B2 CS 1762 A CS1762 A CS 1762A CS 176259 A CS176259 A CS 176259A CS 161826 B2 CS161826 B2 CS 161826B2
Authority
CS
Czechoslovakia
Application number
CS1762A
Other languages
Czech (cs)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of CS161826B2 publication Critical patent/CS161826B2/cs

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J15/00Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Conveying And Assembling Of Building Elements In Situ (AREA)
CS1762A 1958-04-12 1959-04-10 CS161826B2 (US08197722-20120612-C00042.png)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL226774 1958-04-12
NL232312 1958-10-15
NL236884 1959-03-07

Publications (1)

Publication Number Publication Date
CS161826B2 true CS161826B2 (US08197722-20120612-C00042.png) 1975-06-10

Family

ID=27351008

Family Applications (2)

Application Number Title Priority Date Filing Date
CS2095A CS149567B2 (US08197722-20120612-C00042.png) 1958-04-12 1959-04-10
CS1762A CS161826B2 (US08197722-20120612-C00042.png) 1958-04-12 1959-04-10

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS2095A CS149567B2 (US08197722-20120612-C00042.png) 1958-04-12 1959-04-10

Country Status (13)

Country Link
US (4) US3192201A (US08197722-20120612-C00042.png)
AT (2) AT281307B (US08197722-20120612-C00042.png)
CH (14) CH430710A (US08197722-20120612-C00042.png)
CS (2) CS149567B2 (US08197722-20120612-C00042.png)
DE (1) DE1253707B (US08197722-20120612-C00042.png)
DK (7) DK103510C (US08197722-20120612-C00042.png)
ES (1) ES248593A1 (US08197722-20120612-C00042.png)
FI (2) FI42083B (US08197722-20120612-C00042.png)
FR (1) FR953M (US08197722-20120612-C00042.png)
GB (5) GB929276A (US08197722-20120612-C00042.png)
NO (1) NO122835B (US08197722-20120612-C00042.png)
OA (1) OA02640A (US08197722-20120612-C00042.png)
SE (9) SE342814B (US08197722-20120612-C00042.png)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH430710A (de) * 1958-04-12 1967-02-28 Philips Nv Verfahren zur Herstellung neuer Steroide
DE1217374B (de) * 1962-07-10 1966-05-26 Ciba Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung von Zl4,zl5-, oder z)'.4-3-Oxo-10asteroiden
US3235573A (en) * 1962-12-20 1966-02-15 Syntex Corp 19-lower alkylidene and 19-oxo-delta4-androsten-17beta-ol-3-one derivatives
NL123937C (US08197722-20120612-C00042.png) * 1963-11-06
US3463852A (en) * 1966-01-14 1969-08-26 Schering Corp Treating allergies with steroids of the pregnane series
CH476711A (de) * 1966-06-10 1969-08-15 Hoffmann La Roche Verfahren zur Herstellung von neuen 9B,10a-Steroiden
GB1266361A (US08197722-20120612-C00042.png) * 1969-07-16 1972-03-08
US5922699A (en) * 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
CN113880904B (zh) * 2020-07-01 2024-04-12 苏州朗科生物技术股份有限公司 合成地屈孕酮的新方法及化合物
CN114057820B (zh) * 2021-11-15 2023-06-27 湖南科瑞生物制药股份有限公司 一种地屈孕酮的精制方法
CN114957370B (zh) * 2021-12-06 2023-09-19 湖南醇康医药科技有限公司 一种地屈孕酮的制备和纯化方法
CN114957369B (zh) * 2021-12-07 2023-10-31 湖南醇康医药科技有限公司 一种地屈孕酮的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE882399C (de) * 1937-11-28 1953-07-09 Schering Ag Verfahren zur Darstellung von 17-AEthinyl-?-androstenol-17-on-3 und dessen Derivaten
US2752337A (en) * 1951-06-28 1956-06-26 Upjohn Co Steroid enamines
US2739974A (en) * 1953-04-06 1956-03-27 Searle & Co Process of preparing delta4,6-3-ketosteroids
US2871245A (en) * 1956-06-19 1959-01-27 Ciba Pharm Prod Inc New 1-dehydro-testosterones and esters thereof
US2867630A (en) * 1958-06-09 1959-01-06 Upjohn Co 6-fluoro androstenes
CH430710A (de) * 1958-04-12 1967-02-28 Philips Nv Verfahren zur Herstellung neuer Steroide
GB956691A (en) * 1961-10-05 1964-04-29 British Drug Houses Ltd 3-unsubstituted-í¸-androstene compounds

Also Published As

Publication number Publication date
DK103510C (da) 1966-01-17
FI42212B (US08197722-20120612-C00042.png) 1970-03-02
CH415613A (de) 1966-06-30
CH415615A (de) 1966-06-30
SE341399B (US08197722-20120612-C00042.png) 1971-12-27
GB929279A (en) 1963-06-19
CH415614A (de) 1966-06-30
CH432505A (de) 1967-03-31
DE1253707B (de) 1967-11-09
CH432506A (de) 1967-03-31
SE342445B (US08197722-20120612-C00042.png) 1972-02-07
CH420130A (de) 1966-09-15
FR953M (US08197722-20120612-C00042.png) 1961-11-27
DK110201C (da) 1970-11-30
SE341394B (US08197722-20120612-C00042.png) 1971-12-27
GB929271A (en) 1963-06-19
DK124079B (da) 1972-09-11
SE341397B (US08197722-20120612-C00042.png) 1971-12-27
CH428720A (de) 1967-01-31
DK118503B (da) 1970-08-31
DK115038B (da) 1969-09-01
CH455765A (de) 1968-05-15
NO122835B (US08197722-20120612-C00042.png) 1971-08-23
AT281307B (de) 1970-05-25
CH434244A (de) 1967-04-30
US3445489A (en) 1969-05-20
FI42083B (US08197722-20120612-C00042.png) 1970-02-02
CH430710A (de) 1967-02-28
CH420131A (de) 1966-09-15
US3192201A (en) 1965-06-29
CH416612A (de) 1966-07-15
DK107871C (da) 1967-07-17
SE341401B (US08197722-20120612-C00042.png) 1971-12-27
CS149567B2 (US08197722-20120612-C00042.png) 1973-07-25
GB929277A (en) 1963-06-19
US3362968A (en) 1968-01-09
SE342814B (US08197722-20120612-C00042.png) 1972-02-21
CH441299A (de) 1967-08-15
SE341400B (US08197722-20120612-C00042.png) 1971-12-27
SE341398B (US08197722-20120612-C00042.png) 1971-12-27
GB929276A (en) 1963-06-19
AT287213B (de) 1971-01-11
CH464183A (de) 1968-10-31
OA02640A (fr) 1970-12-15
US3373172A (en) 1968-03-12
DK108571C (da) 1968-01-08
SE341848B (US08197722-20120612-C00042.png) 1972-01-17
GB929278A (en) 1963-06-19
ES248593A1 (es) 1959-11-16

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