CO6361907A2 - Suministro transdermico de farmaco empleando un osmolito y un agente vasoactivo - Google Patents
Suministro transdermico de farmaco empleando un osmolito y un agente vasoactivoInfo
- Publication number
- CO6361907A2 CO6361907A2 CO11045145A CO11045145A CO6361907A2 CO 6361907 A2 CO6361907 A2 CO 6361907A2 CO 11045145 A CO11045145 A CO 11045145A CO 11045145 A CO11045145 A CO 11045145A CO 6361907 A2 CO6361907 A2 CO 6361907A2
- Authority
- CO
- Colombia
- Prior art keywords
- vasoactive agent
- osmolit
- transdermic
- farmaco
- supply
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00902—Plasters containing means
- A61F2013/00906—Plasters containing means for transcutaneous or transdermal drugs application
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Una formulación y método para el suministro de sustancias bioactivas cuando se a aplican a, o dentro, de la piel u otra región exterior de un mamífero, por ejemplo un paciente, incluye un agente vasoactivo; un osmolito; y un ingrediente activo; La formulación es lo suficientemente higroscópica para crear una condición de hipertonicidad cuando es absorbida por la piel; Cuando la formulación se aplica a la piel, el agente vasoactivo puede administrarse a la dermis para hacer contacto con la vasculatura de un paciente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9912908P | 2008-09-22 | 2008-09-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6361907A2 true CO6361907A2 (es) | 2012-01-20 |
Family
ID=41449932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO11045145A CO6361907A2 (es) | 2008-09-22 | 2011-04-12 | Suministro transdermico de farmaco empleando un osmolito y un agente vasoactivo |
Country Status (7)
Country | Link |
---|---|
US (3) | US9566256B2 (es) |
EP (1) | EP2207536A1 (es) |
BR (1) | BRPI0914192A2 (es) |
CA (1) | CA2702604C (es) |
CO (1) | CO6361907A2 (es) |
MX (1) | MX349176B (es) |
WO (1) | WO2010034019A1 (es) |
Families Citing this family (19)
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US9566256B2 (en) * | 2008-09-22 | 2017-02-14 | Biochemics, Inc. | Transdermal drug delivery using an osmolyte and vasoactive agent |
BRPI0921959A2 (pt) | 2008-12-04 | 2017-05-30 | Biochemics Inc | métodos e composições para remoção de tatuagem |
WO2012046149A1 (en) | 2010-04-28 | 2012-04-12 | Kimberly-Clark Worldwide, Inc. | Method for increasing permeability of an epithelial barrier |
CA2797205C (en) | 2010-04-28 | 2019-04-16 | Kimberly-Clark Worldwide, Inc. | Medical devices for delivery of sirna |
PT2563450T (pt) | 2010-04-28 | 2017-08-28 | Kimberly Clark Co | Dispositivo para entrega de medicação para a artrite reumatóide |
AU2011288209C1 (en) | 2010-04-28 | 2016-03-24 | Kimberly-Clark Worldwide, Inc. | Injection molded microneedle array and method for forming the microneedle array |
US8512770B2 (en) | 2010-08-04 | 2013-08-20 | Dominion Resources Unlimited, Llc | Skin penetration composition |
WO2013061209A1 (en) | 2011-10-27 | 2013-05-02 | Kimberly-Clark Worldwide, Inc. | Implantable devices for delivery of bioactive agents |
KR20220051429A (ko) | 2011-10-27 | 2022-04-26 | 소렌토 쎄라퓨틱스, 인코포레이티드 | 고점도 생체활성 제제의 경피 전달 방법 |
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WO2013083431A1 (en) | 2011-12-06 | 2013-06-13 | Unilever Plc | Skin anti-ageing composition |
US9587169B2 (en) * | 2012-01-12 | 2017-03-07 | Courtney Gene Rogers | Low-toxicity, low-flammability, environmentally-safe, friction reducer fluid for hydraulic fracturing |
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WO2015066699A1 (en) * | 2013-11-04 | 2015-05-07 | ROGERS, Courtney, Gene | Low-toxicity, low-flammability, environmentally-safe, friction reducer fluid for hydraulic fracturing |
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IT201800003902A1 (it) * | 2018-03-23 | 2019-09-23 | Sebastiano Turrini | Unguento a base di ibuprofene racemico transedermico |
MX2021002833A (es) * | 2018-09-27 | 2021-05-27 | Biophysics Pharma Inc | Sistema de suministro de farmaco transdermico. |
AU2021224149A1 (en) * | 2020-02-20 | 2022-09-15 | John J. Masiz | Transmucosal drug delivery system |
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CA2680823A1 (en) * | 2007-03-19 | 2008-09-25 | Sirtris Pharmaceuticals, Inc. | Biomarkers of sirtuin activity and methods of use thereof |
US8354116B2 (en) | 2007-06-18 | 2013-01-15 | Biochemics, Inc. | Bifunctional synthetic molecules |
US20090123570A1 (en) * | 2007-11-09 | 2009-05-14 | Warner W Randolph | Composition and method for treating sore throat |
WO2009094473A1 (en) * | 2008-01-22 | 2009-07-30 | Biochemics, Inc. | Methods and compositions for topical treatment of medical conditions including wounds and inflammation |
WO2009111075A2 (en) | 2008-03-07 | 2009-09-11 | Frank Pellegrini | Ultra bright led induced tattoo removal |
CA2727710C (en) | 2008-06-11 | 2016-11-01 | Biochemics, Inc. | Control of blood vessel physiology to treat skin disorders |
AU2009291755B2 (en) | 2008-09-10 | 2016-04-21 | Biochemics, Inc. | Ibuprofen for topical administration |
US9566256B2 (en) | 2008-09-22 | 2017-02-14 | Biochemics, Inc. | Transdermal drug delivery using an osmolyte and vasoactive agent |
BRPI0921959A2 (pt) | 2008-12-04 | 2017-05-30 | Biochemics Inc | métodos e composições para remoção de tatuagem |
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2009
- 2009-09-22 US US12/564,841 patent/US9566256B2/en active Active
- 2009-09-22 WO PCT/US2009/057916 patent/WO2010034019A1/en active Application Filing
- 2009-09-22 EP EP09740777A patent/EP2207536A1/en not_active Withdrawn
- 2009-09-22 MX MX2010004169A patent/MX349176B/es active IP Right Grant
- 2009-09-22 BR BRPI0914192A patent/BRPI0914192A2/pt not_active IP Right Cessation
- 2009-09-22 CA CA2702604A patent/CA2702604C/en not_active Expired - Fee Related
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2011
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2015
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2016
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US20160128957A1 (en) | 2016-05-12 |
US20100076035A1 (en) | 2010-03-25 |
BRPI0914192A2 (pt) | 2015-11-03 |
US9566256B2 (en) | 2017-02-14 |
MX2010004169A (es) | 2010-10-05 |
EP2207536A1 (en) | 2010-07-21 |
CA2702604A1 (en) | 2010-03-25 |
WO2010034019A4 (en) | 2010-05-20 |
CA2702604C (en) | 2013-12-03 |
MX349176B (es) | 2017-07-14 |
WO2010034019A1 (en) | 2010-03-25 |
US10751309B2 (en) | 2020-08-25 |
US20160129116A1 (en) | 2016-05-12 |
US10537536B2 (en) | 2020-01-21 |
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