CO6290669A2 - Usos terapeuticos de compuestos que tiene afinidad con el transportador de serotonina los receptores de serotonina y transportador de noraadrenalina - Google Patents
Usos terapeuticos de compuestos que tiene afinidad con el transportador de serotonina los receptores de serotonina y transportador de noraadrenalinaInfo
- Publication number
- CO6290669A2 CO6290669A2 CO10070917A CO10070917A CO6290669A2 CO 6290669 A2 CO6290669 A2 CO 6290669A2 CO 10070917 A CO10070917 A CO 10070917A CO 10070917 A CO10070917 A CO 10070917A CO 6290669 A2 CO6290669 A2 CO 6290669A2
- Authority
- CO
- Colombia
- Prior art keywords
- disorder
- depression
- dementia
- disease
- anxiety
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Pulmonology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Se proporcionan usos terapéuticos de la 4-[2-(4-metilfenilsulfanil)fenil]piperidina y sus sales terapéuticamente aceptables.1.- Un método para tratar una enfermedad seleccionada entre retardo psicomotriz; depresión severa; trastorno distímico; ciclotimia; trastorno de ánimo debido a una condición médica generalizada; depresión inducida por sustancias; depresión recurrente; depresión de episodio único; depresión pediátrica; depresión atípica; depresión post-accidente cerebrovascular; depresión por extenuación; depresión asociada con dolor gastrointestinal, lBS, abuso, hostilidad, irritabilidad, fatiga, ansiedad (depresión ansiosa), enfermedad del Cuerpo de Lewy, enfermedad de Huntington, o esclerosis múltiple; trastorno de ansiedad generalizada asociado con dolor; trastorno afectivo estacional (SAD); depresión o ansiedad en pacientes con riesgo incrementado de hipertensión; depresión o ansiedad en pacientes con problemas de sueño; trastorno relacionado con el estrés; estrés agudo; demencia; deterioro cognitivo leve (MCI); demencia vascular; leucariosis; enfermedad de los vasos menores; deterioro cognitivo asociado con trastornos afectivos, depresión, depresión generalizada, trastorno depresivo grave, trastornos por ansiedad, trastorno por ansiedad generalizada, trastorno por pánico, trastorno obsesivo-compulsivo, esquizofrenia, enfermedad de Parkinson, demencia, demencia por SIDA, ADHD, deterioro de la memoria asociado con la edad, síndrome de Down, epilepsia, lesión cerebral traumática, síndrome de Asperger, y mutaciones del gen de la triptófano hidrolasa; trastorno disfórico pre-, peri- o post-menstrual; llanto patológico; autismo; obesidad; anorexia; bulimia; comilonas; trastorno del control de impulsos; trastorno explosivo intermitente; cleptomanía; piromanía; juego patológico; tricotilomanía; trastorno de la conducta; agotamiento; estrés; síndrome de fatiga crónica; trastorno del ritmo circadiano; trastorno del sueño; apnea del sueño; síndrome de hipopnea; alteraciones de la conducta; alteraciones de la conducta en la tercera edad; alteraciones de la conducta asociadas con la demencia; trastorno compulsivo y del espectro de atención asociado con ADHD, síndrome de Asperger y autismo; agresión y agitación en la demencia y la enfermedad de Alzheimer; resistencia a la insulina asociada con hiperactividad del eje HPA; síndrome del latigazo (whiplash); miedo a volar, a los ascensores o a los espacios restringidos; y ambliopía; comprendiendo el método la administración de una cantidad terapéuticamente efectiva de 4-[2-(4-metilfenilsulfanil)fenil]piperidina y sales de ésta terapéuticamenta aceptables (compuesto I) a un paciente que lo necesita.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200701791 | 2007-12-14 | ||
DKPA200701798 | 2007-12-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6290669A2 true CO6290669A2 (es) | 2011-06-20 |
Family
ID=40285887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO10070917A CO6290669A2 (es) | 2007-12-14 | 2010-06-11 | Usos terapeuticos de compuestos que tiene afinidad con el transportador de serotonina los receptores de serotonina y transportador de noraadrenalina |
Country Status (18)
Country | Link |
---|---|
US (3) | US20110053978A1 (es) |
EP (1) | EP2231154A1 (es) |
JP (1) | JP2011506353A (es) |
KR (1) | KR20100092956A (es) |
CN (1) | CN102202666A (es) |
AR (1) | AR069904A1 (es) |
AU (1) | AU2008338059A1 (es) |
BR (1) | BRPI0819914A2 (es) |
CA (1) | CA2708786A1 (es) |
CL (1) | CL2008003709A1 (es) |
CO (1) | CO6290669A2 (es) |
EA (1) | EA201070737A1 (es) |
IL (1) | IL205965A0 (es) |
MX (1) | MX2010005795A (es) |
NZ (1) | NZ586010A (es) |
SG (1) | SG185984A1 (es) |
TW (1) | TW200938194A (es) |
WO (1) | WO2009076962A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS52205B2 (sr) | 2006-06-16 | 2021-05-31 | H Lundbeck A/S | 1-[2-(2,4-dimetilfenilsulfanil)-fenil]piperazin kao jedinjenje sa kombinovanom aktivnošću ponovnog uzimanja serotonina, 5-ht3 i 5-ht1a, za tretman kognitivnih oštećenja |
TWI432194B (zh) * | 2007-03-20 | 2014-04-01 | Lundbeck & Co As H | 4-〔2-(4-甲基苯硫基)苯基〕哌啶之新穎治療用途 |
KR20130060220A (ko) * | 2010-04-30 | 2013-06-07 | 다케다 야쿠힌 고교 가부시키가이샤 | 장용성 정제 |
CN104710345B (zh) * | 2013-12-17 | 2017-09-05 | 江苏恩华药业股份有限公司 | 用于制备4‑(2‑(4‑甲基苯基硫基))苯基哌啶的化合物、其制备方法及应用 |
CN104120177A (zh) * | 2014-06-11 | 2014-10-29 | 杭州艾迪康医学检验中心有限公司 | 检测5-httlpr片段多态性的方法和引物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
US7732463B2 (en) * | 2003-04-04 | 2010-06-08 | H. Lundbeck A/S | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors |
PL2044020T3 (pl) * | 2006-06-16 | 2011-09-30 | H Lundbeck As | Krystaliczne postaci 4-[2-(4-metylofenylosulfanylo)-fenylo]piperydyny z równoczesnym hamowaniem wychwytu zwrotnego serotoniny i norepinefryny do leczenia bólu neuropatycznego |
TWI432194B (zh) * | 2007-03-20 | 2014-04-01 | Lundbeck & Co As H | 4-〔2-(4-甲基苯硫基)苯基〕哌啶之新穎治療用途 |
JP5764327B2 (ja) * | 2007-06-15 | 2015-08-19 | ハー・ルンドベック・アクチエゼルスカベット | 過敏性腸症候群(ibs)を処置するための4−[2−(4−メチルフェニルスルファニル)フェニル]ピペリジン |
-
2008
- 2008-12-02 TW TW097146699A patent/TW200938194A/zh unknown
- 2008-12-11 WO PCT/DK2008/050302 patent/WO2009076962A1/en active Application Filing
- 2008-12-11 CA CA2708786A patent/CA2708786A1/en not_active Abandoned
- 2008-12-11 US US12/747,403 patent/US20110053978A1/en not_active Abandoned
- 2008-12-11 EA EA201070737A patent/EA201070737A1/ru unknown
- 2008-12-11 BR BRPI0819914A patent/BRPI0819914A2/pt not_active IP Right Cessation
- 2008-12-11 MX MX2010005795A patent/MX2010005795A/es not_active Application Discontinuation
- 2008-12-11 AU AU2008338059A patent/AU2008338059A1/en not_active Abandoned
- 2008-12-11 KR KR1020107013095A patent/KR20100092956A/ko not_active Application Discontinuation
- 2008-12-11 CN CN2008801203913A patent/CN102202666A/zh active Pending
- 2008-12-11 SG SG2012083010A patent/SG185984A1/en unknown
- 2008-12-11 JP JP2010537257A patent/JP2011506353A/ja active Pending
- 2008-12-11 NZ NZ586010A patent/NZ586010A/xx not_active IP Right Cessation
- 2008-12-11 EP EP08862439A patent/EP2231154A1/en not_active Withdrawn
- 2008-12-12 CL CL2008003709A patent/CL2008003709A1/es unknown
- 2008-12-12 AR ARP080105414A patent/AR069904A1/es not_active Application Discontinuation
-
2010
- 2010-05-25 IL IL205965A patent/IL205965A0/en unknown
- 2010-06-11 CO CO10070917A patent/CO6290669A2/es not_active Application Discontinuation
-
2014
- 2014-05-16 US US14/279,504 patent/US20140296290A1/en not_active Abandoned
-
2016
- 2016-05-03 US US15/145,102 patent/US20170087138A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2008338059A1 (en) | 2009-06-25 |
IL205965A0 (en) | 2010-11-30 |
MX2010005795A (es) | 2010-08-31 |
TW200938194A (en) | 2009-09-16 |
CN102202666A (zh) | 2011-09-28 |
US20140296290A1 (en) | 2014-10-02 |
EA201070737A1 (ru) | 2010-12-30 |
SG185984A1 (en) | 2012-12-28 |
JP2011506353A (ja) | 2011-03-03 |
WO2009076962A1 (en) | 2009-06-25 |
CL2008003709A1 (es) | 2010-01-15 |
CA2708786A1 (en) | 2009-06-25 |
KR20100092956A (ko) | 2010-08-23 |
US20170087138A1 (en) | 2017-03-30 |
EP2231154A1 (en) | 2010-09-29 |
AR069904A1 (es) | 2010-03-03 |
BRPI0819914A2 (pt) | 2016-05-17 |
NZ586010A (en) | 2012-08-31 |
US20110053978A1 (en) | 2011-03-03 |
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