CO5700832A2 - Suspensiones acuosas de ciclesonide para nebulizacion - Google Patents

Suspensiones acuosas de ciclesonide para nebulizacion

Info

Publication number
CO5700832A2
CO5700832A2 CO06054801A CO06054801A CO5700832A2 CO 5700832 A2 CO5700832 A2 CO 5700832A2 CO 06054801 A CO06054801 A CO 06054801A CO 06054801 A CO06054801 A CO 06054801A CO 5700832 A2 CO5700832 A2 CO 5700832A2
Authority
CO
Colombia
Prior art keywords
ciclesonide
nebulization
suspensions
waterproof
aqueous suspension
Prior art date
Application number
CO06054801A
Other languages
English (en)
Spanish (es)
Inventor
Scheffler Antje Brueck
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34684543&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO5700832(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of CO5700832A2 publication Critical patent/CO5700832A2/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CO06054801A 2003-12-16 2006-06-07 Suspensiones acuosas de ciclesonide para nebulizacion CO5700832A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03028848 2003-12-16

Publications (1)

Publication Number Publication Date
CO5700832A2 true CO5700832A2 (es) 2006-11-30

Family

ID=34684543

Family Applications (1)

Application Number Title Priority Date Filing Date
CO06054801A CO5700832A2 (es) 2003-12-16 2006-06-07 Suspensiones acuosas de ciclesonide para nebulizacion

Country Status (21)

Country Link
US (2) US20070117783A1 (enExample)
EP (2) EP2319858B1 (enExample)
JP (1) JP5001657B2 (enExample)
KR (1) KR101086095B1 (enExample)
CN (1) CN100513417C (enExample)
AR (1) AR046892A1 (enExample)
AU (1) AU2004298447B2 (enExample)
BR (1) BRPI0416854B8 (enExample)
CA (1) CA2549038C (enExample)
CO (1) CO5700832A2 (enExample)
EA (1) EA012388B1 (enExample)
EC (1) ECSP066608A (enExample)
IL (1) IL175461A (enExample)
MY (1) MY159377A (enExample)
NO (1) NO337225B1 (enExample)
NZ (1) NZ547217A (enExample)
PE (1) PE20050941A1 (enExample)
TW (1) TWI350757B (enExample)
UA (1) UA87123C2 (enExample)
WO (1) WO2005058935A2 (enExample)
ZA (1) ZA200603768B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022796A1 (en) * 2007-08-07 2009-02-11 Nycomed GmbH Amorphous ciclesonide
US7984792B2 (en) * 2008-03-03 2011-07-26 Rolls-Royce Corporation Lubrication system
US20110262420A1 (en) * 2008-12-03 2011-10-27 Ltt Bio-Pharma Co., Ltd. Inhalant comprising modified superoxide dismutase
CA2806559C (en) 2009-09-02 2018-06-26 Synedgen Inc. Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
ES2913095T3 (es) * 2011-01-31 2022-05-31 Avalyn Pharma Inc Compuestos de pirfenidona y análogos de piridona en aerosol y usos de los mismos
EP2741736B1 (en) 2011-08-12 2017-11-22 Boehringer Ingelheim Vetmedica GmbH Taste masked pharmaceutical composition
CA2844944A1 (en) 2011-08-18 2013-02-21 Takeda Gmbh Pharmaceutical aerosol product for administration by oral or nasal inhalation
KR102045723B1 (ko) 2011-09-14 2019-11-18 시오노기 앤드 컴파니, 리미티드 흡입용 의약 조성물
ES2909039T3 (es) 2012-12-21 2022-05-05 Boehringer Ingelheim Vetmedica Gmbh Formulación farmacéutica que comprende ciclesonida
AU2013360691B2 (en) 2012-12-21 2018-03-08 Boehringer Ingelheim Vetmedica Gmbh Ciclesonide for the treatment of airway disease in horses
AU2015204558B2 (en) 2014-01-10 2020-04-30 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
LT3157522T (lt) 2014-06-18 2019-11-25 Boehringer Ingelheim Vetmedica Gmbh Muskarininiai antagonistai ir jų deriniai, skirti arklių kvėpavimo takų ligos gydymui
JP2017526714A (ja) * 2014-09-11 2017-09-14 シネジェン, インコーポレイテッド 組成物およびその使用方法
CN107847482A (zh) * 2015-08-05 2018-03-27 第三共株式会社 喷雾器用组合物
CN106692163A (zh) * 2015-11-13 2017-05-24 天津金耀集团有限公司 一种吸入用环索奈德混悬液组合物
WO2019090405A1 (pt) * 2017-11-11 2019-05-16 Carvalho Junior Mario Virgilio De Medicamento de ciclesonida para cura e prevenção da gripe causada pelo vírus influenza
US20220023282A1 (en) * 2018-12-13 2022-01-27 Mannkind Corporation Compositions of Bedaquiline, Combinations Comprising Them, Processes for Their Preparation, Uses and Methods of Treatment Comprising Them
US20210346613A1 (en) * 2020-05-05 2021-11-11 Mahesh Kumar KHAITAN Controlled delivery device for treating coronavirus infections and methods thereof
WO2021262648A1 (en) * 2020-06-23 2021-12-30 Anovent Pharmaceutical (U.S.), Llc Preparation of a pharmaceutical composition of olodaterol and budesonide
WO2022213101A1 (en) * 2021-04-01 2022-10-06 Vitrean Inc. Methods for manufacturing of highly concentrated hydrogels
WO2022231533A1 (en) * 2021-04-29 2022-11-03 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Process for the preparation of sterilized suspensions for the inhalation by nebulization

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE458986B (sv) * 1985-03-29 1989-05-29 Draco Ab Dosfoerpackning
SE8600632D0 (sv) 1986-02-13 1986-02-13 Kabivitrum Ab Novel pharmaceutical composition
GR1001529B (el) * 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
US5346702A (en) * 1992-12-04 1994-09-13 Sterling Winthrop Inc. Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
SK281226B6 (sk) * 1993-04-02 2001-01-18 Byk Gulden Lomberg Chemische Fabrik Gmbh Prednizolónové deriváty, liečivá s ich obsahom a ich použitie
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
GB9410222D0 (en) 1994-05-21 1994-07-06 Glaxo Wellcome Australia Ltd Medicaments
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
DE19541689A1 (de) 1994-11-14 1996-05-15 Byk Gulden Lomberg Chem Fab Kombinationsarzneimittel
DE19635498A1 (de) 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung
US6120752A (en) 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
SE9704186D0 (sv) 1997-11-14 1997-11-14 Astra Ab New composition of matter
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
TWI243687B (en) * 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
US6264923B1 (en) * 1998-05-13 2001-07-24 3M Innovative Properties Company Medicinal aerosol formulation of ciclesonide and related compounds
US8415329B1 (en) 1998-05-29 2013-04-09 Jagotec Ag Thermoprotected compositions and process for terminal steam sterilization of microparticle preparations
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
IT1313553B1 (it) * 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
AR026072A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa
EP1142565A4 (en) 1999-10-20 2004-03-17 Teijin Ltd AQUEOUS THERAPEUTIC COMPOSITIONS
AR026073A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
US20020183292A1 (en) * 2000-10-31 2002-12-05 Michel Pairet Pharmaceutical compositions based on anticholinergics and corticosteroids
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
DK1337279T3 (da) * 2000-11-24 2006-09-25 Breath Ltd Sterilisation af glucocorticosteroidsuspensioner
US6667344B2 (en) * 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
DE10145361A1 (de) * 2001-09-14 2003-04-03 Pari Gmbh Verfahren zur Herstellung von flüssigen, sterilen Zubereitungen zur Inhalation
RU2279292C2 (ru) * 2001-10-24 2006-07-10 Пари Гмбх Набор для приготовления фармацевтической композиции
AU2003246829A1 (en) 2002-02-19 2003-09-09 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
ATE352564T1 (de) 2002-03-04 2007-02-15 Nymox Corp Spheron-komponenten für die bestimmung von verbindungen, die symptome der alzheimer krankheit behandeln können, ihre behandlungen und tiermodelle
CN100475229C (zh) 2002-04-12 2009-04-08 味之素株式会社 预防动脉硬化的组合物
ITMI20020808A1 (it) * 2002-04-17 2003-10-17 Chiesi Farma Spa Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione
JP4364486B2 (ja) 2002-07-02 2009-11-18 帝人株式会社 無菌水性懸濁製剤
CN100366256C (zh) * 2002-07-02 2008-02-06 奥坦纳医药公司 含有环索奈德的无菌水性混悬剂
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
KR101067795B1 (ko) * 2002-08-30 2011-09-27 니코메드 게엠베하 알레르기성 비염을 치료하기 위한 사이클레소나이드 및 항히스타민제의 조합물의 용도
JP3857708B2 (ja) 2002-09-24 2006-12-13 富士通株式会社 歪み波形制御装置、歪み規制部材、歪み波形制御装置の歪み波形制御方法、及び歪み波形制御プログラム
AU2003268380A1 (en) 2002-10-04 2004-05-04 Elan Pharma International Limited Gamma irradiation of solid nanoparticulate active agents
ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
EP1454636A1 (en) 2003-03-04 2004-09-08 Dompé S.P.A. Sterilization of glucocorticoid drug particles for pulmonary delivery
MY143936A (en) 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
ES2452691T5 (es) * 2003-09-16 2022-09-14 Covis Pharma Gmbh Uso de ciclesonida para el tratamiento de enfermedades respiratorias
DE10347994A1 (de) 2003-10-15 2005-06-16 Pari GmbH Spezialisten für effektive Inhalation Wässrige Aerosol-Zubereitung
ATE497787T1 (de) 2004-03-12 2011-02-15 Cipla Ltd Sterilisationsprozess für steroide
GB0410995D0 (en) 2004-05-17 2004-06-23 Norton Healthcare Ltd Heat sterilization of glucocorticosteroids
ITSA20040012A1 (it) 2004-09-07 2004-12-07 Genetec S P A Processo di sterilizzazione di un glucocorticosteroide.
GB0425266D0 (en) 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process

Also Published As

Publication number Publication date
US20160015634A1 (en) 2016-01-21
TW200524615A (en) 2005-08-01
US11052042B2 (en) 2021-07-06
PE20050941A1 (es) 2005-11-08
EP2319858B1 (en) 2017-08-09
HK1098486A1 (zh) 2007-07-20
UA87123C2 (uk) 2009-06-25
CA2549038C (en) 2014-08-05
NO20063047L (no) 2006-09-05
EP1697398A2 (en) 2006-09-06
US20070117783A1 (en) 2007-05-24
ECSP066608A (es) 2006-10-25
CA2549038A1 (en) 2005-06-30
BRPI0416854B1 (pt) 2018-05-02
IL175461A (en) 2013-12-31
BRPI0416854A (pt) 2007-02-13
JP2007513993A (ja) 2007-05-31
EP1697398B1 (en) 2012-07-04
CN100513417C (zh) 2009-07-15
AR046892A1 (es) 2005-12-28
CN1890256A (zh) 2007-01-03
EA200601091A1 (ru) 2006-12-29
TWI350757B (en) 2011-10-21
EP2319858A1 (en) 2011-05-11
BRPI0416854B8 (pt) 2021-05-25
IL175461A0 (en) 2006-09-05
EA012388B1 (ru) 2009-10-30
WO2005058935A2 (en) 2005-06-30
JP5001657B2 (ja) 2012-08-15
NZ547217A (en) 2009-05-31
KR20060122890A (ko) 2006-11-30
KR101086095B1 (ko) 2011-11-25
AU2004298447A1 (en) 2005-06-30
MY159377A (en) 2016-12-30
ZA200603768B (en) 2007-10-31
AU2004298447B2 (en) 2011-04-21
WO2005058935A3 (en) 2006-05-18
NO337225B1 (no) 2016-02-15

Similar Documents

Publication Publication Date Title
CO5700832A2 (es) Suspensiones acuosas de ciclesonide para nebulizacion
ECSP045491A (es) Nueva sal formiato de o-desmetil venlafaxina
ECSP088332A (es) Compuesto, composiciones y usos de isoindole-imide
ATE520007T1 (de) Bildgebungsgeometrie
ITPD20000208A0 (it) Polisaccaridi percarbossilati, processo per la loro preparazione e loro impiego in campo farmaceutico e biomedico-sanitario.
CY1110878T1 (el) Διαδικασιες για την μετρηση της ισχυος του glatiramer acetate
CO4560552A1 (es) Antagonistas de receptores de taquicininas no peptidicos
UY27455A1 (es) Derivados n-(1,4,5,6-tetrahidro-ciclopentapirazol -3-il)- sustituidos. su obtención y uso como fármacos.
BRPI0519298A2 (pt) mÉtodo de preparaÇço de um tecido biolàgico fixado
BRPI0212137A2 (pt) diidropteridinonas, processos para prepará-las e seu uso como composições farmacêuticas
NO20034149D0 (no) Legemidler inneholdende triazaspiro[5.5]undekanderivater som den aktive bestanddel
ATE352395T1 (de) Vertikales stentschneidsystem
DE502004008588D1 (de) Agrochemische formulierungen
AR034213A1 (es) Composiciones de medicamentos sobre la base de agentes anticolinergicos e inhibidores de pde-iv
AR034517A1 (es) Formulacion farmaceutica
CY1107451T1 (el) Υδροβρωμικον escitalopram και μεθοδος δια την παρασκευη αυτου
ITMI20011762A0 (it) Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione
ES2134197T3 (es) Vacunas contra el virus del herpes simplex vp16.
BRPI0510778B8 (pt) composição farmacêutica, processo para preparação da :mesma, e, uso de uma composição
ITRM20030363A0 (it) Composizioni comprendenti la 3, 5diiodotironina e uso farmaceutico diesse.
DOP2002000457A (es) Tetrahidroquinolinas
NO20054535L (no) Bifunksjonelle heterocykliske forbindelser og fremgangsmater for fremstilling og anvendelse av samme
DE50213507D1 (de) Verfahren und mittel zur beeinflussung von interzellulärer kommunikation und interzellulärem organellentransport
IT1284873B1 (it) Derivati stabili di ubichinolo procedimenti per la loro produzione e loro impiego farmaceutico
BRPI0516464B8 (pt) método para a preparação de um produto farmacêutico

Legal Events

Date Code Title Description
FG Application granted