CO5031290A1 - Formulacion lo - Google Patents

Formulacion lo

Info

Publication number
CO5031290A1
CO5031290A1 CO97042583A CO97042583A CO5031290A1 CO 5031290 A1 CO5031290 A1 CO 5031290A1 CO 97042583 A CO97042583 A CO 97042583A CO 97042583 A CO97042583 A CO 97042583A CO 5031290 A1 CO5031290 A1 CO 5031290A1
Authority
CO
Colombia
Prior art keywords
pharmaceutically acceptable
methoxyimino
azabicyclo
acetonitrile
oct
Prior art date
Application number
CO97042583A
Other languages
English (en)
Inventor
Dirk Marinus Johannes Van-Schie
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of CO5031290A1 publication Critical patent/CO5031290A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Un medicamento que contiene [R-(Z)]-a-(metoxiimino)-a-(1-azabiciclo[2.2.2]oct-3-il) acetonitrilo, o una sal farmacéuticamente aceptable del mismo, para el tratamiento, y/o la profilaxis de la demencia en seres humanos, que está adaptado para ser aplicado a la piel.Un método para el tratamiento y/o la profilaxis de la demencia de seres humanos mediante la administración a la piel de [R-(Z)]-a-(metoxiimino)-a-(1-azabiciclo[2.2.2]oct-3-il)acetonitrilo, o una sal farmacèuticamente aceptable del mismo.Una composición farmacéutica para la administración a la piel, que comprende [R-(Z)]-a-(metoxiimino)-a-(1-azabiciclo[2.2.2]oct-3-il)acetonitrilo, o una sal farmacéuticamente aceptable del mismo, junto con vehículo adecuado farmacéuticamente aceptable.
CO97042583A 1996-07-25 1997-07-25 Formulacion lo CO5031290A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9615628.6A GB9615628D0 (en) 1996-07-25 1996-07-25 Formulation

Publications (1)

Publication Number Publication Date
CO5031290A1 true CO5031290A1 (es) 2001-04-27

Family

ID=10797487

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97042583A CO5031290A1 (es) 1996-07-25 1997-07-25 Formulacion lo

Country Status (24)

Country Link
EP (1) EP0918521B1 (es)
JP (1) JP2000515868A (es)
KR (1) KR20000029523A (es)
CN (1) CN1226163A (es)
AR (1) AR007983A1 (es)
AT (1) ATE224711T1 (es)
BR (1) BR9710546A (es)
CA (1) CA2261233A1 (es)
CO (1) CO5031290A1 (es)
CZ (1) CZ22799A3 (es)
DE (1) DE69715878T2 (es)
DK (1) DK0918521T3 (es)
ES (1) ES2184121T3 (es)
GB (1) GB9615628D0 (es)
HK (1) HK1021314A1 (es)
IL (1) IL128095A (es)
NO (1) NO990283L (es)
NZ (1) NZ333704A (es)
PL (1) PL331283A1 (es)
PT (1) PT918521E (es)
TR (1) TR199900141T2 (es)
TW (1) TW426514B (es)
WO (1) WO1998004258A1 (es)
ZA (1) ZA976592B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9815383D0 (en) * 1998-07-15 1998-09-16 Smithkline Beecham Plc Novel method of treatment
US6835850B2 (en) * 2000-09-27 2004-12-28 Dsw Ip Assets B.V. Process for the carbonylation of a conjugated diene
GB0428170D0 (en) * 2004-12-23 2005-01-26 Biopartners Ltd Mono and Combination Therapy
SG11202005962YA (en) 2017-12-29 2020-07-29 Guangzhou Maxinovel Pharmaceuticals Co Ltd Aromatic vinyl or aromatic ethyl derivative, preparation method therefor, intermediate, pharmaceutical composition, and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0392803B1 (en) * 1989-04-13 2004-06-16 Beecham Group p.l.c. Novel compounds
MX9300875A (es) * 1992-02-20 1993-08-31 Smithkline Beecham Plc Procedimiento para la preparacion de compuestos azabiciclicos.
GB9409705D0 (en) * 1994-05-14 1994-07-06 Smithkline Beecham Plc Novel compounds
DE19501022C1 (de) * 1995-01-14 1996-06-05 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Verabreichung von (s)-3-Methyl-5-(1-methyl-2-pyrrolidenyl)-isoxazol oder einem seiner pharmazeutisch akzeptablen Salze und Verfahren zu seiner Herstellung

Also Published As

Publication number Publication date
TR199900141T2 (xx) 1999-03-22
GB9615628D0 (en) 1996-09-04
TW426514B (en) 2001-03-21
DE69715878T2 (de) 2003-05-22
CA2261233A1 (en) 1998-02-05
PT918521E (pt) 2003-02-28
ZA976592B (en) 1999-03-04
WO1998004258A1 (en) 1998-02-05
BR9710546A (pt) 1999-08-17
NZ333704A (en) 2000-06-23
ATE224711T1 (de) 2002-10-15
HK1021314A1 (en) 2000-06-09
AU721101B2 (en) 2000-06-22
IL128095A0 (en) 1999-11-30
KR20000029523A (ko) 2000-05-25
NO990283L (no) 1999-03-19
CZ22799A3 (cs) 1999-06-16
DE69715878D1 (de) 2002-10-31
DK0918521T3 (da) 2003-02-03
CN1226163A (zh) 1999-08-18
NO990283D0 (no) 1999-01-22
EP0918521B1 (en) 2002-09-25
PL331283A1 (en) 1999-07-05
EP0918521A1 (en) 1999-06-02
JP2000515868A (ja) 2000-11-28
AU3768497A (en) 1998-02-20
IL128095A (en) 2002-07-25
AR007983A1 (es) 1999-11-24
ES2184121T3 (es) 2003-04-01

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