CO4910160A1 - FORMULATIONS AND POLYMORPHIC FORMS OF DESPHERRIOXAMINE AND ITS PREPARATION - Google Patents

FORMULATIONS AND POLYMORPHIC FORMS OF DESPHERRIOXAMINE AND ITS PREPARATION

Info

Publication number
CO4910160A1
CO4910160A1 CO97072069A CO97072069A CO4910160A1 CO 4910160 A1 CO4910160 A1 CO 4910160A1 CO 97072069 A CO97072069 A CO 97072069A CO 97072069 A CO97072069 A CO 97072069A CO 4910160 A1 CO4910160 A1 CO 4910160A1
Authority
CO
Colombia
Prior art keywords
preparation
despherrioxamine
formulations
polymorphic forms
desferrioxamine
Prior art date
Application number
CO97072069A
Other languages
Spanish (es)
Inventor
Ian Francis-Hass
Nicholas Lowther
Joanne Nicklin
Alan Steward
Peter Van Hoogevest
Erwim Marti
Andre Joseph Geoffroy
Hans Hirt
Andreas Burkhard
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625878.5A external-priority patent/GB9625878D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO4910160A1 publication Critical patent/CO4910160A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una composición parenteralmente inyectable quecomprende partículas de una sal de desferrioxamina-B de un ácido sulfónico alifático que tiene cuando menos 8 átomos de carbono, suspendida en un aceite parenteralmente administrable.8- Un método para la preparación de una composición de acuerdo con cualquiera de las reivindicaciones 1 a 7, el cual comprende mezclar partículas de la sal de desferrioxamina-B con el aceite parenteralmente administrable, y en donde esté presente, el tensoactivo.A parenterally injectable composition comprising particles of a desferrioxamine-B salt of an aliphatic sulfonic acid having at least 8 carbon atoms, suspended in a parenterally administrable oil.8- A method for the preparation of a composition according to any of the Claims 1 to 7, which comprises mixing particles of the desferrioxamine-B salt with the parenterally administrable oil, and where present, the surfactant.

CO97072069A 1996-12-10 1997-12-10 FORMULATIONS AND POLYMORPHIC FORMS OF DESPHERRIOXAMINE AND ITS PREPARATION CO4910160A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH302496 1996-12-10
GBGB9625878.5A GB9625878D0 (en) 1996-12-12 1996-12-12 Compositions

Publications (1)

Publication Number Publication Date
CO4910160A1 true CO4910160A1 (en) 2000-04-24

Family

ID=25691970

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97072069A CO4910160A1 (en) 1996-12-10 1997-12-10 FORMULATIONS AND POLYMORPHIC FORMS OF DESPHERRIOXAMINE AND ITS PREPARATION

Country Status (15)

Country Link
EP (1) EP0944586A2 (en)
KR (1) KR20000069376A (en)
CN (1) CN1239946A (en)
AR (1) AR009655A1 (en)
AU (1) AU5983998A (en)
BR (1) BR9713570A (en)
CA (1) CA2274761A1 (en)
CO (1) CO4910160A1 (en)
CZ (1) CZ204499A3 (en)
ID (1) ID22388A (en)
IL (1) IL130203A0 (en)
PE (1) PE27799A1 (en)
PL (1) PL334316A1 (en)
TR (1) TR199901260T2 (en)
WO (1) WO1998025887A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2395314A1 (en) * 1999-12-23 2001-11-15 Neurochem, Inc. Compounds and methods for modulating cerebral amyloid angiopathy
GB0117645D0 (en) 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
DE10223913A1 (en) * 2002-05-29 2003-12-11 Bayer Cropscience Ag Process for the production of specific crystal modifications of polymorphic substances
CN108290878B (en) 2015-10-23 2022-04-26 威佛（国际）股份公司 Novel ferroportin inhibitors
JOP20180036A1 (en) 2017-04-18 2019-01-30 Vifor Int Ag Novel ferroportin-inhibitor salts
TW202102478A (en) 2019-04-01 2021-01-16 瑞士商威佛（國際）股份有限公司 Novel iron chelators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH438351A (en) * 1959-09-25 1967-06-30 Ciba Geigy Process for the production of new growth substances
FR1898M (en) * 1961-04-07 1963-07-08 Ciba Geigy New substance usable in therapy.
GB9211779D0 (en) * 1992-06-03 1992-07-15 Ciba Geigy Ag Amine salts

Also Published As

Publication number Publication date
CN1239946A (en) 1999-12-29
AR009655A1 (en) 2000-04-26
TR199901260T2 (en) 1999-10-21
KR20000069376A (en) 2000-11-25
IL130203A0 (en) 2000-06-01
WO1998025887A3 (en) 1998-08-13
EP0944586A2 (en) 1999-09-29
CZ204499A3 (en) 1999-09-15
AU5983998A (en) 1998-07-03
WO1998025887A2 (en) 1998-06-18
PE27799A1 (en) 1999-03-18
ID22388A (en) 1999-10-07
PL334316A1 (en) 2000-02-14
CA2274761A1 (en) 1998-06-18
BR9713570A (en) 2000-03-14

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