BR9713570A - Polymorphic formulations and forms of desferrioxamine and their preparation. - Google Patents

Polymorphic formulations and forms of desferrioxamine and their preparation.

Info

Publication number
BR9713570A
BR9713570A BR9713570-4A BR9713570A BR9713570A BR 9713570 A BR9713570 A BR 9713570A BR 9713570 A BR9713570 A BR 9713570A BR 9713570 A BR9713570 A BR 9713570A
Authority
BR
Brazil
Prior art keywords
desferrioxamine
preparation
forms
formulations
salt
Prior art date
Application number
BR9713570-4A
Other languages
Portuguese (pt)
Inventor
Erwin Marti
Andre Joseph Geoffroy
Hans Hirt
Andreas Burkhard
Ian Francis Hassan
Nicholas Lowther
Joanne Nicklin
Alan Steward
Peter Van Hoogevest
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9625878.5A external-priority patent/GB9625878D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9713570A publication Critical patent/BR9713570A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção:<B>"FORMULAçõES E FORMAS POLIMóRFICAS DE DESFERRIOXAMINA E A SUA PREPARAçãO"<D>. Uma composição parenteralmente injetável que compreende partículas de um sal de desferrioxamina-B de um ácido sulfónico alifático tendo pelo menos 8 átomos de carbono em um óleo parenteralmente administrável. Novas modificações cristalinas de sal decano sulfónico de desferrioxamina são proporcionadas, e é mostrada uma forma de cristal com notável estabilidade.Invention Patent: <B> "FORMULATIONS AND POLYMORPHIC FORMS OF DESFERRIOXAMINE AND THEIR PREPARATION" <D>. A parenterally injectable composition comprising particles of a desferrioxamine-B salt of an aliphatic sulfonic acid having at least 8 carbon atoms in a parenterally administrable oil. New crystalline modifications of the desferrioxamine sulfonic decane salt are provided, and a crystal form with remarkable stability is shown.

BR9713570-4A 1996-12-10 1997-12-08 Polymorphic formulations and forms of desferrioxamine and their preparation. BR9713570A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH302496 1996-12-10
GBGB9625878.5A GB9625878D0 (en) 1996-12-12 1996-12-12 Compositions
PCT/EP1997/006849 WO1998025887A2 (en) 1996-12-10 1997-12-08 Formulations and polymorphic forms of desferrioxamine and the preparation thereof

Publications (1)

Publication Number Publication Date
BR9713570A true BR9713570A (en) 2000-03-14

Family

ID=25691970

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9713570-4A BR9713570A (en) 1996-12-10 1997-12-08 Polymorphic formulations and forms of desferrioxamine and their preparation.

Country Status (15)

Country Link
EP (1) EP0944586A2 (en)
KR (1) KR20000069376A (en)
CN (1) CN1239946A (en)
AR (1) AR009655A1 (en)
AU (1) AU5983998A (en)
BR (1) BR9713570A (en)
CA (1) CA2274761A1 (en)
CO (1) CO4910160A1 (en)
CZ (1) CZ204499A3 (en)
ID (1) ID22388A (en)
IL (1) IL130203A0 (en)
PE (1) PE27799A1 (en)
PL (1) PL334316A1 (en)
TR (1) TR199901260T2 (en)
WO (1) WO1998025887A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1251837A2 (en) * 1999-12-23 2002-10-30 Neurochem, Inc. Compounds and methods for modulating cerebral amyloid angiopathy
GB0117645D0 (en) * 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
DE10223913A1 (en) * 2002-05-29 2003-12-11 Bayer Cropscience Ag Process for the production of specific crystal modifications of polymorphic substances
WO2017068090A1 (en) 2015-10-23 2017-04-27 Vifor (International) Ag Novel ferroportin inhibitors
JOP20180036A1 (en) 2017-04-18 2019-01-30 Vifor Int Ag Novel ferroportin-inhibitor salts
TW202102478A (en) 2019-04-01 2021-01-16 瑞士商威佛（國際）股份有限公司 Novel iron chelators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH438351A (en) * 1959-09-25 1967-06-30 Ciba Geigy Process for the production of new growth substances
FR1898M (en) * 1961-04-07 1963-07-08 Ciba Geigy New substance usable in therapy.
GB9211779D0 (en) * 1992-06-03 1992-07-15 Ciba Geigy Ag Amine salts

Also Published As

Publication number Publication date
EP0944586A2 (en) 1999-09-29
TR199901260T2 (en) 1999-10-21
CZ204499A3 (en) 1999-09-15
ID22388A (en) 1999-10-07
CO4910160A1 (en) 2000-04-24
IL130203A0 (en) 2000-06-01
PE27799A1 (en) 1999-03-18
AR009655A1 (en) 2000-04-26
CA2274761A1 (en) 1998-06-18
WO1998025887A3 (en) 1998-08-13
CN1239946A (en) 1999-12-29
KR20000069376A (en) 2000-11-25
PL334316A1 (en) 2000-02-14
AU5983998A (en) 1998-07-03
WO1998025887A2 (en) 1998-06-18

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]