CO4750820A1 - COMPOSITIONS CONTAINING AN ANALGESIC PHARMACEUTICAL ASSET AND AN ANTIHISTAMINE AGENT OF PIRROLIDINE OR PIPERIDINE ETHER AND, OPTIONALLY, AN ALPHA-AGONIST AND / OR CAFFEINE COMPOUND - Google Patents

COMPOSITIONS CONTAINING AN ANALGESIC PHARMACEUTICAL ASSET AND AN ANTIHISTAMINE AGENT OF PIRROLIDINE OR PIPERIDINE ETHER AND, OPTIONALLY, AN ALPHA-AGONIST AND / OR CAFFEINE COMPOUND

Info

Publication number
CO4750820A1
CO4750820A1 CO96039940A CO96039940A CO4750820A1 CO 4750820 A1 CO4750820 A1 CO 4750820A1 CO 96039940 A CO96039940 A CO 96039940A CO 96039940 A CO96039940 A CO 96039940A CO 4750820 A1 CO4750820 A1 CO 4750820A1
Authority
CO
Colombia
Prior art keywords
pirrolidine
agonist
alpha
optionally
compositions containing
Prior art date
Application number
CO96039940A
Other languages
Spanish (es)
Inventor
Ronald Dean Cramer
Sekhar Mitra
Donald Kay Riker
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of CO4750820A1 publication Critical patent/CO4750820A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

.- la presente invención se refiere a composiciones para proveer untratamiento mejorado, manejo o mitigación de los síntomas del resfriado, similares al resfriado, alergia, sinusitis y/o de la gripe, mediante la administración de una cantidad segura y eficaz de una composición que consiste esencialmente de: (a) un activo farmacéutico analgésico; y (b) un agente antihistamínico de éter de pirrolidina o piperidina de la fórmula: en donde R1 es un radical que se selecciona del grupo que consiste de hidrógeno, halógeno, alquilo inferior que contiene de 1 a 4 átomos de carbono, R2 es un radical que se selecciona del grupo que consiste de alquilo inferior que contiene de 1 a 4 átomos de carbono, m es un número entero de 0, 1, 2 y 3 y n es un número entero de 1 a 2, con la condición de que m + n debe ser por lo menos 2.The present invention relates to compositions to provide improved treatment, management, or mitigation of cold, allergy, sinus, and / or flu-like symptoms of the cold by administering a safe and effective amount of a composition that It consists essentially of: (a) a pharmaceutical pain reliever; and (b) a pyrrolidine or piperidine ether antihistamine agent of the formula: wherein R1 is a radical selected from the group consisting of hydrogen, halogen, lower alkyl containing 1 to 4 carbon atoms, R2 is a radical selected from the group consisting of lower alkyl containing from 1 to 4 carbon atoms, m is an integer from 0, 1, 2 and 3 and n is an integer from 1 to 2, with the proviso that m + n must be at least 2.

CO96039940A 1995-07-28 1996-07-29 COMPOSITIONS CONTAINING AN ANALGESIC PHARMACEUTICAL ASSET AND AN ANTIHISTAMINE AGENT OF PIRROLIDINE OR PIPERIDINE ETHER AND, OPTIONALLY, AN ALPHA-AGONIST AND / OR CAFFEINE COMPOUND CO4750820A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50877595A 1995-07-28 1995-07-28
US61152896A 1996-03-05 1996-03-05

Publications (1)

Publication Number Publication Date
CO4750820A1 true CO4750820A1 (en) 1999-03-31

Family

ID=27056302

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96039940A CO4750820A1 (en) 1995-07-28 1996-07-29 COMPOSITIONS CONTAINING AN ANALGESIC PHARMACEUTICAL ASSET AND AN ANTIHISTAMINE AGENT OF PIRROLIDINE OR PIPERIDINE ETHER AND, OPTIONALLY, AN ALPHA-AGONIST AND / OR CAFFEINE COMPOUND

Country Status (8)

Country Link
EP (1) EP0841947A1 (en)
JP (1) JPH11510168A (en)
AR (1) AR003470A1 (en)
AU (1) AU6599196A (en)
CA (1) CA2227958A1 (en)
CO (1) CO4750820A1 (en)
PE (1) PE12098A1 (en)
WO (1) WO1997004808A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
US5770618A (en) * 1996-11-13 1998-06-23 Nastech Pharmaceutical Company, Inc. Method for increasing the solubility of clemastine and pharmaceutical compositions prepared therefrom
HUP9700654A2 (en) * 1997-03-26 1999-09-28 Dezső Korbonits Antitussive compositions containing theobromine
AU8744398A (en) * 1997-09-19 1999-04-12 Procter & Gamble Company, The Compositions and methods for treating respiratory disorders
DE60232445D1 (en) 2001-06-28 2009-07-09 Ucb Farchim Sa CETIRIC AND PSEUDOEPHEDRINE-CONTAINING TABLET
KR20040045429A (en) * 2001-09-04 2004-06-01 베링거 인겔하임 인터내셔날 게엠베하 Anti-influenza drugs
US7863287B2 (en) * 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
FR2865648B1 (en) 2004-02-03 2006-06-30 Philippe Perovitch METHOD FOR DIFFUSION OF INSOLUBLE MOLECULES IN AQUEOUS MEDIUM AND COMPOSITION IMPLEMENTING SAID METHOD
RU2286770C2 (en) * 2004-11-22 2006-11-10 Закрытое акционерное общество "Научно-производственное объединение "Антивирал" (ЗАО "НПО "Антивирал") Anti-influenza agent
JP5598108B2 (en) * 2009-07-09 2014-10-01 ライオン株式会社 Solid composition for internal use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59222406A (en) * 1983-06-01 1984-12-14 Teijin Ltd Pharmaceutical preparation for remedying periodontosis and its preparation
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
EP0550668A4 (en) * 1990-09-28 1993-10-13 Merck & Co. Inc. Ibuprofen-antihistamine combinations
EP0661967B1 (en) * 1991-11-19 1999-08-25 University Of Virginia Patent Foundation Combined virustatic antimediator (covam) treatment of common colds
GB9222849D0 (en) * 1992-10-31 1992-12-16 Smithkline Beecham Plc Novel use of pharmaceutical compositions
AU672279B2 (en) * 1992-12-21 1996-09-26 Procter & Gamble Company, The Compositions containing caffeine and S(+)-ibuprofen or S(+)-flurbiprofen or S(+)-ketoprofen

Also Published As

Publication number Publication date
CA2227958A1 (en) 1997-02-13
JPH11510168A (en) 1999-09-07
PE12098A1 (en) 1998-04-19
WO1997004808A1 (en) 1997-02-13
AR003470A1 (en) 1998-08-05
AU6599196A (en) 1997-02-26
EP0841947A1 (en) 1998-05-20

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