PE12098A1 - COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERS - Google Patents

COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERS

Info

Publication number
PE12098A1
PE12098A1 PE1996000570A PE00057096A PE12098A1 PE 12098 A1 PE12098 A1 PE 12098A1 PE 1996000570 A PE1996000570 A PE 1996000570A PE 00057096 A PE00057096 A PE 00057096A PE 12098 A1 PE12098 A1 PE 12098A1
Authority
PE
Peru
Prior art keywords
compositions
methods
alkyl
formula
respiratory disorders
Prior art date
Application number
PE1996000570A
Other languages
Spanish (es)
Inventor
Donald Kay Riker
Ronald Dean Cramer
Sekhar Mitra
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of PE12098A1 publication Critical patent/PE12098A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

CARACTERIZADO PORQUE COMPRENDE: 1) UN ANALGESICO, S(+) ENANTIOMERO, TAL COMO: IBUPROFENO O NAPROXENO, ENTRE OTROS, COMO SAL DE LISINA; 2) UN ANTIHISTAMINICOS DE ETER DE PIRROLIDINA Y PIPERIDINA, DE FORMULA (I), EN DONDE: R1 ES H, HALO, ALQUILO C1-C4 O ALCOXI C1-C4; R2 ES ALQUILO C1-C4; m ES 0; 1; 2 o 3; n ES 1 o 2; SE REFIERE PREFERENTEMENTE AL FUMARATO DE CLEMASTINA; 3) EXCIPIENTES; ADEMAS AL MENOS UNO DE LOS SIGUIENTES PRINCIPIOS ACTIVOS: 4) UN DESCONGESTIONANTE TAL COMO PSEUDOEFEDRINA; 5) UN EXPECTORANTE; 6) UN ANTIHISTAMINICO ADICIONAL; 7) ANTITUSIVO TAL COMO DEXTROMETORFANO HBr; 8) UN COMPUESTO ALFA AGONISTA; Y OPCIONALMENTE, 9) UNA CANTIDAD EFICAZ DE CAFEINA, PARA DISMINUIR LOS EFECTOS SEDANTES DEL ANTIHISTAMINICO DE FORMULA (I). UTIL PARA ALIVIAR LOS SINTOMAS DEL RESFRIADO, SINUSITIS, ENTRE OTROSCHARACTERIZED BECAUSE IT INCLUDES: 1) AN ANALGESIC, S (+) ENANTIOMERO, SUCH AS: IBUPROFEN OR NAPROXENO, AMONG OTHERS, AS LYSINE SALT; 2) AN ANTIHISTAMINES OF PIRROLIDINE AND PIPERIDINE ETHER, OF FORMULA (I), WHERE: R1 IS H, HALO, C1-C4 ALKYL OR C1-C4 ALCOXY; R2 IS C1-C4 ALKYL; m IS 0; one; 2 or 3; n IS 1 or 2; IT PREFERABLY REFERS TO CLUMASTINE FUMARATE; 3) EXCIPIENTS; IN ADDITION TO AT LEAST ONE OF THE FOLLOWING ACTIVE PRINCIPLES: 4) A DISCONNECTING SUCH AS PSEUDOEFEDRINE; 5) AN EXPECTORANT; 6) AN ADDITIONAL ANTIHISTAMINIC; 7) ANTITUSIVE SUCH AS DEXTROMETHORPHAN HBr; 8) AN ALPHA AGONIST COMPOUND; AND OPTIONALLY, 9) AN EFFECTIVE AMOUNT OF CAFFEINE, TO REDUCE THE SEDANING EFFECTS OF THE FORMULA ANTIHISTAMINE (I). USEFUL TO RELIEF THE SYMPTOMS OF COLD, SINUSITIS, AMONG OTHERS

PE1996000570A 1995-07-28 1996-07-26 COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERS PE12098A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50877595A 1995-07-28 1995-07-28
US61152896A 1996-03-05 1996-03-05

Publications (1)

Publication Number Publication Date
PE12098A1 true PE12098A1 (en) 1998-04-19

Family

ID=27056302

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1996000570A PE12098A1 (en) 1995-07-28 1996-07-26 COMPOSITIONS AND METHODS FOR TREATING RESPIRATORY DISORDERS

Country Status (8)

Country Link
EP (1) EP0841947A1 (en)
JP (1) JPH11510168A (en)
AR (1) AR003470A1 (en)
AU (1) AU6599196A (en)
CA (1) CA2227958A1 (en)
CO (1) CO4750820A1 (en)
PE (1) PE12098A1 (en)
WO (1) WO1997004808A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
US5770618A (en) * 1996-11-13 1998-06-23 Nastech Pharmaceutical Company, Inc. Method for increasing the solubility of clemastine and pharmaceutical compositions prepared therefrom
HUP9700654A2 (en) * 1997-03-26 1999-09-28 Dezső Korbonits Antitussive compositions containing theobromine
AU8744398A (en) * 1997-09-19 1999-04-12 Procter & Gamble Company, The Compositions and methods for treating respiratory disorders
DE60232445D1 (en) 2001-06-28 2009-07-09 Ucb Farchim Sa CETIRIC AND PSEUDOEPHEDRINE-CONTAINING TABLET
KR20040045429A (en) * 2001-09-04 2004-06-01 베링거 인겔하임 인터내셔날 게엠베하 Anti-influenza drugs
US7863287B2 (en) * 2002-12-18 2011-01-04 Wyeth Llc Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
FR2865648B1 (en) 2004-02-03 2006-06-30 Philippe Perovitch METHOD FOR DIFFUSION OF INSOLUBLE MOLECULES IN AQUEOUS MEDIUM AND COMPOSITION IMPLEMENTING SAID METHOD
RU2286770C2 (en) * 2004-11-22 2006-11-10 Закрытое акционерное общество "Научно-производственное объединение "Антивирал" (ЗАО "НПО "Антивирал") Anti-influenza agent
JP5598108B2 (en) * 2009-07-09 2014-10-01 ライオン株式会社 Solid composition for internal use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59222406A (en) * 1983-06-01 1984-12-14 Teijin Ltd Pharmaceutical preparation for remedying periodontosis and its preparation
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
EP0550668A4 (en) * 1990-09-28 1993-10-13 Merck & Co. Inc. Ibuprofen-antihistamine combinations
EP0661967B1 (en) * 1991-11-19 1999-08-25 University Of Virginia Patent Foundation Combined virustatic antimediator (covam) treatment of common colds
GB9222849D0 (en) * 1992-10-31 1992-12-16 Smithkline Beecham Plc Novel use of pharmaceutical compositions
AU672279B2 (en) * 1992-12-21 1996-09-26 Procter & Gamble Company, The Compositions containing caffeine and S(+)-ibuprofen or S(+)-flurbiprofen or S(+)-ketoprofen

Also Published As

Publication number Publication date
CA2227958A1 (en) 1997-02-13
JPH11510168A (en) 1999-09-07
CO4750820A1 (en) 1999-03-31
WO1997004808A1 (en) 1997-02-13
AR003470A1 (en) 1998-08-05
AU6599196A (en) 1997-02-26
EP0841947A1 (en) 1998-05-20

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Legal Events

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