AR003470A1 - COMPOSITION TO PROVIDE IMPROVED TREATMENT OR ATTENUATION OF SYMPTOMS OF COLD, ALLERGY, SINUSITIS OR INFLUENZA COMPOSED BY AN ANALYSIS ACTIVE AND ANTIHISTAMINE AGENT OF PIRRILIDONE OR PIPERIDINE - Google Patents

COMPOSITION TO PROVIDE IMPROVED TREATMENT OR ATTENUATION OF SYMPTOMS OF COLD, ALLERGY, SINUSITIS OR INFLUENZA COMPOSED BY AN ANALYSIS ACTIVE AND ANTIHISTAMINE AGENT OF PIRRILIDONE OR PIPERIDINE

Info

Publication number
AR003470A1
AR003470A1 ARP960103779A AR10377996A AR003470A1 AR 003470 A1 AR003470 A1 AR 003470A1 AR P960103779 A ARP960103779 A AR P960103779A AR 10377996 A AR10377996 A AR 10377996A AR 003470 A1 AR003470 A1 AR 003470A1
Authority
AR
Argentina
Prior art keywords
salts
pharmaceutically acceptable
compositions
sinusitis
allergy
Prior art date
Application number
ARP960103779A
Other languages
Spanish (es)
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of AR003470A1 publication Critical patent/AR003470A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

Esta invención se refiere a composiciones y métodos para proporcionar tratamiento o atenuación mejorada de síntomas de resfríos, alergia, sinusitisy/o gripe, mediante la administración de una cantidad segura y eficaz de una composición que contiene un agente analgésico y agentes antihistamínicos deéter de pirrolidina y piperidina. Los activos farmacéuticos analgésicos útiles en las composiciones de esta invención incluyen aspirina y acetaminofeno asícomo drogas antiinflamatorias sin esteroides (NSAIDS) seleccionadas de las siguientes categorías: derivados de ácido propiónico; derivados de ácidoacético; derivados de ácido fenámico; derivados de ácido bifenilcarboxílico; y oxicamas. Ejemplos de activos farmacéuticos analgésicos útiles en estainvención incluyen, entre otros, acetaminofeno, ácido acetilsalicílico, ibuprofeno, fenbuprofeno, flurbiprofeno, indometacina, quetoprofeno, naproxeno,sus sales farmacéuticamente aceptables, sus enantiómeros y mezclas.Elacetaminofeno, ibuprofeno y naproxeno son especialmente preferidos para su usoen composiciones de esta invención. La expresión sales farmacéuticamente aceptables se refiere a sales preparadas a partir de bases no tóxicasfarmacéuticamente aceptables, incluyendo bases orgánicas e inorgánicas. Las sales derivadas de bases no orgánicas incluyen sales de sodio, potasio, litio,amonio, calcio, magnesio, ferrosa, de zinc, manganosa, de aluminio, férrica, mangánica, etc. Las sales derivadas de bases no tóxicas farmacéuticamenteaceptables incluyen sales de aminas primarias, secundarias, terciarias y cuaternarias, aminas sustituidas, incluyendo aminas sustituidas de origennatural,aminas cíclicas y resinas de cambio de ion básico,por ej. trietilamina, tripropilamina, 2-dimetilaminoetanol, 2-dietilaminoetanol, lisina, arginina,This invention relates to compositions and methods for providing treatment or improved alleviation of symptoms of colds, allergy, sinusitis and / or flu, by administering a safe and effective amount of a composition containing an analgesic agent and pyrrolidine ether antihistamine agents and piperidine. Analgesic pharmaceutical actives useful in the compositions of this invention include aspirin and acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDS) selected from the following categories: propionic acid derivatives; acetic acid derivatives; derivatives of fenamic acid; biphenylcarboxylic acid derivatives; and oxicams. Examples of analgesic pharmaceutical actives useful in this invention include, but are not limited to, acetaminophen, acetylsalicylic acid, ibuprofen, fenbuprofen, flurbiprofen, indomethacin, ketoprofen, naproxen, their pharmaceutically acceptable salts, their enantiomers, and mixtures. use in compositions of this invention. The term "pharmaceutically acceptable salts" refers to salts prepared from non-toxic pharmaceutically acceptable bases, including organic and inorganic bases. Salts derived from non-organic bases include salts of sodium, potassium, lithium, ammonium, calcium, magnesium, ferrous, zinc, manganose, aluminum, ferric, manganic, etc. Salts derived from pharmaceutically acceptable non-toxic bases include salts of primary, secondary, tertiary and quaternary amines, substituted amines, including substituted amines of natural origin, cyclic amines and basic ion exchange resins, eg. triethylamine, tripropylamine, 2-dimethylaminoethanol, 2-diethylaminoethanol, lysine, arginine,

ARP960103779A 1995-07-28 1996-07-26 COMPOSITION TO PROVIDE IMPROVED TREATMENT OR ATTENUATION OF SYMPTOMS OF COLD, ALLERGY, SINUSITIS OR INFLUENZA COMPOSED BY AN ANALYSIS ACTIVE AND ANTIHISTAMINE AGENT OF PIRRILIDONE OR PIPERIDINE AR003470A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50877595A 1995-07-28 1995-07-28
US61152896A 1996-03-05 1996-03-05

Publications (1)

Publication Number Publication Date
AR003470A1 true AR003470A1 (en) 1998-08-05

Family

ID=27056302

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103779A AR003470A1 (en) 1995-07-28 1996-07-26 COMPOSITION TO PROVIDE IMPROVED TREATMENT OR ATTENUATION OF SYMPTOMS OF COLD, ALLERGY, SINUSITIS OR INFLUENZA COMPOSED BY AN ANALYSIS ACTIVE AND ANTIHISTAMINE AGENT OF PIRRILIDONE OR PIPERIDINE

Country Status (8)

Country Link
EP (1) EP0841947A1 (en)
JP (1) JPH11510168A (en)
AR (1) AR003470A1 (en)
AU (1) AU6599196A (en)
CA (1) CA2227958A1 (en)
CO (1) CO4750820A1 (en)
PE (1) PE12098A1 (en)
WO (1) WO1997004808A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
US5770618A (en) * 1996-11-13 1998-06-23 Nastech Pharmaceutical Company, Inc. Method for increasing the solubility of clemastine and pharmaceutical compositions prepared therefrom
HUP9700654A2 (en) * 1997-03-26 1999-09-28 Dezső Korbonits Antitussive compositions containing theobromine
EP1014983A1 (en) * 1997-09-19 2000-07-05 The Procter & Gamble Company Naproxen/cetirizine compositions and methods for treating respiratory disorders
IL159287A0 (en) 2001-06-28 2004-06-01 Ucb Farchim Sa Tablet comprising cetirizine and pseudoephedrine
WO2003020258A1 (en) * 2001-09-04 2003-03-13 Boehringer Ingelheim International Gmbh Anti-influenza drugs
CL2003002653A1 (en) * 2002-12-18 2005-04-22 Wyeth Corp PHARMACEUTICAL COMPOSITION THAT INCLUDES (A) AN NON-STEROID ANTI-INFLAMMATORY (NSAID), PREFERREDLY IBUPROFEN, (B) A DECONGESTIONANT, PREFERENTIALLY PSEUDOEFEDRINE AND (C) AN ANTIHISTAMINIC, PREFERENTLY CHLORINE; METHOD FOR YOUR PREPARATION
FR2865648B1 (en) 2004-02-03 2006-06-30 Philippe Perovitch METHOD FOR DIFFUSION OF INSOLUBLE MOLECULES IN AQUEOUS MEDIUM AND COMPOSITION IMPLEMENTING SAID METHOD
RU2286770C2 (en) * 2004-11-22 2006-11-10 Закрытое акционерное общество "Научно-производственное объединение "Антивирал" (ЗАО "НПО "Антивирал") Anti-influenza agent
JP5598108B2 (en) * 2009-07-09 2014-10-01 ライオン株式会社 Solid composition for internal use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59222406A (en) * 1983-06-01 1984-12-14 Teijin Ltd Pharmaceutical preparation for remedying periodontosis and its preparation
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
AU8764191A (en) * 1990-09-28 1992-04-28 Mcneill-Ppc Inc. Ibuprofen-antihistamine combinations
ES2137981T3 (en) * 1991-11-19 2000-01-01 Univ Virginia COMBINED TREATMENT BY ANTIMEDIATIC AND ANTIVIRIC AGENTS OF COMMON COLDS.
GB9222849D0 (en) * 1992-10-31 1992-12-16 Smithkline Beecham Plc Novel use of pharmaceutical compositions
BR9307697A (en) * 1992-12-21 1999-05-25 Procter & Gamble Compositions containing caffeine and s (+) - ibuprofen or s (+) - flubiprofen or s (+) - quetoprofen

Also Published As

Publication number Publication date
CO4750820A1 (en) 1999-03-31
WO1997004808A1 (en) 1997-02-13
AU6599196A (en) 1997-02-26
EP0841947A1 (en) 1998-05-20
PE12098A1 (en) 1998-04-19
JPH11510168A (en) 1999-09-07
CA2227958A1 (en) 1997-02-13

Similar Documents

Publication Publication Date Title
Mauleón et al. Preclinical and clinical development of dexketoprofen
EP0311677B1 (en) Cough/cold mixtures comprising non-sedating antihistamine drugs
AR064895A2 (en) PHARMACEUTICAL COMPOSITION ANHIDRA FOR THE TREATMENT OF HISTAMINE INDUCED DISORDERS
AR003470A1 (en) COMPOSITION TO PROVIDE IMPROVED TREATMENT OR ATTENUATION OF SYMPTOMS OF COLD, ALLERGY, SINUSITIS OR INFLUENZA COMPOSED BY AN ANALYSIS ACTIVE AND ANTIHISTAMINE AGENT OF PIRRILIDONE OR PIPERIDINE
JP6397100B2 (en) Pharmaceutical composition 3 containing loxoprofen
JP2763634B2 (en) Onset enhanced / augmented analgesia
JP4043046B2 (en) Nitro compounds having anti-inflammatory, analgesic and antithrombotic activity and compositions thereof
ES2397262T3 (en) Fast absorbing liquid compositions containing an amine and an NSAID
SE7910371L (en) ORAL ADMINISTRATIVE MEDICINE WITH INFLAMMATION DISABILITY EFFECT
US4871733A (en) Cough/cold mixtures comprising non-sedating antihistamine drugs
KR920016086A (en) Nonsteroidal anti-inflammatory drugs with reactivity inhibitory asthma treatment for inhalation
AR012376A1 (en) GEL FORMULATION FOR TOPIC APPLICATION
NO20001290D0 (en) Multiple-unit compositions of non-steroidal anti-inflammatory drug (NSAID) with modified release
US5968974A (en) Method of treating colonic adenomas
CO5280050A1 (en) Denaturing for the sympathomimetic amine salts
CO6180502A2 (en) Chewable tablet containing phenylephrine
UY24816A1 (en) PROSTAGLANDIN AGONIST SULFONAMIDES FOR THE PREVENTION AND RESTORATION OF THE BONE MASS
UY25441A1 (en) PROCEDURE FOR THE PREPARATION OF GALENIC FORMS OF MELOXICAM FOR ORAL APPLICATION.
ES2148175T3 (en) PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF IBUPROFEN.
CO5011084A1 (en) COMPOSITIONS AND METHODS TO TREAT RESPIRATORY DISORDERS
KR930009605A (en) Anti-inflammatory or analgesic
KR970705390A (en) (COMPOSITION ALLEVIATING PAIN, CONTAINING NON-NARCOTIC ANALGESIC AND AN ANALGESIA ENHANCER) COMPOSITION CONTAINING A NON-NARCOTIC ANALGESIC AND ANALGESIA ENHANCER,
PT805157E (en) INDOLE DERIVATIVES AND THEIR MEDICINAL USE
CA2411960A1 (en) Analgesic and anti-inflammatory compositions containing cox-2 inhibitors
RU2015112586A (en) PHARMACEUTICAL COMPOSITIONS CONTAINING FLURBIPROFEN