CO2024004211A2 - Formulaciones de proteínas quiméricas de factor viii y usos de las mismas - Google Patents
Formulaciones de proteínas quiméricas de factor viii y usos de las mismasInfo
- Publication number
- CO2024004211A2 CO2024004211A2 CONC2024/0004211A CO2024004211A CO2024004211A2 CO 2024004211 A2 CO2024004211 A2 CO 2024004211A2 CO 2024004211 A CO2024004211 A CO 2024004211A CO 2024004211 A2 CO2024004211 A2 CO 2024004211A2
- Authority
- CO
- Colombia
- Prior art keywords
- factor viii
- formulations
- chimeric factor
- viii proteins
- polypeptide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163256432P | 2021-10-15 | 2021-10-15 | |
| PCT/US2022/078097 WO2023064886A1 (en) | 2021-10-15 | 2022-10-14 | Formulations of factor viii chimeric proteins and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2024004211A2 true CO2024004211A2 (es) | 2024-04-18 |
Family
ID=84362012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2024/0004211A CO2024004211A2 (es) | 2021-10-15 | 2024-04-04 | Formulaciones de proteínas quiméricas de factor viii y usos de las mismas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20240358800A1 (https=) |
| EP (1) | EP4415693B1 (https=) |
| JP (1) | JP2024538091A (https=) |
| KR (1) | KR20240082408A (https=) |
| CN (1) | CN118103034A (https=) |
| AU (1) | AU2022366974A1 (https=) |
| CA (1) | CA3229979A1 (https=) |
| CO (1) | CO2024004211A2 (https=) |
| IL (1) | IL311969A (https=) |
| MX (1) | MX2024004494A (https=) |
| TW (1) | TW202334244A (https=) |
| WO (1) | WO2023064886A1 (https=) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2124690C (en) * | 1992-10-02 | 2007-09-11 | Thomas Osterberg | Composition comprising coagulation factor viii formulation, process for its preparation and use of a surfactant as stabilizer |
| PL3793588T3 (pl) * | 2018-05-18 | 2025-09-01 | Bioverativ Therapeutics Inc. | Sposoby leczenia hemofilii a |
-
2022
- 2022-10-14 CN CN202280069172.7A patent/CN118103034A/zh active Pending
- 2022-10-14 JP JP2024522237A patent/JP2024538091A/ja active Pending
- 2022-10-14 TW TW111139016A patent/TW202334244A/zh unknown
- 2022-10-14 KR KR1020247015817A patent/KR20240082408A/ko active Pending
- 2022-10-14 EP EP22813008.4A patent/EP4415693B1/en active Active
- 2022-10-14 WO PCT/US2022/078097 patent/WO2023064886A1/en not_active Ceased
- 2022-10-14 CA CA3229979A patent/CA3229979A1/en active Pending
- 2022-10-14 AU AU2022366974A patent/AU2022366974A1/en active Pending
- 2022-10-14 MX MX2024004494A patent/MX2024004494A/es unknown
- 2022-10-14 IL IL311969A patent/IL311969A/en unknown
-
2024
- 2024-04-04 CO CONC2024/0004211A patent/CO2024004211A2/es unknown
- 2024-04-10 US US18/632,038 patent/US20240358800A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4415693A1 (en) | 2024-08-21 |
| JP2024538091A (ja) | 2024-10-18 |
| MX2024004494A (es) | 2024-07-15 |
| CA3229979A1 (en) | 2023-04-20 |
| CN118103034A (zh) | 2024-05-28 |
| KR20240082408A (ko) | 2024-06-10 |
| EP4415693C0 (en) | 2026-02-18 |
| EP4415693B1 (en) | 2026-02-18 |
| US20240358800A1 (en) | 2024-10-31 |
| TW202334244A (zh) | 2023-09-01 |
| WO2023064886A1 (en) | 2023-04-20 |
| AU2022366974A1 (en) | 2024-05-30 |
| IL311969A (en) | 2024-06-01 |
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