BR112023003010A2 - Método de fracionamento de plasma humano, composição, e, preparações de um fator de coagulação, de igg, de um membro selecionado de a1pi, at-iii e uma combinação dos mesmos e de albumina - Google Patents
Método de fracionamento de plasma humano, composição, e, preparações de um fator de coagulação, de igg, de um membro selecionado de a1pi, at-iii e uma combinação dos mesmos e de albuminaInfo
- Publication number
- BR112023003010A2 BR112023003010A2 BR112023003010A BR112023003010A BR112023003010A2 BR 112023003010 A2 BR112023003010 A2 BR 112023003010A2 BR 112023003010 A BR112023003010 A BR 112023003010A BR 112023003010 A BR112023003010 A BR 112023003010A BR 112023003010 A2 BR112023003010 A2 BR 112023003010A2
- Authority
- BR
- Brazil
- Prior art keywords
- human plasma
- a1pi
- igg
- albumin
- preparations
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000005194 fractionation Methods 0.000 title abstract 4
- 102000009027 Albumins Human genes 0.000 title abstract 2
- 108010088751 Albumins Proteins 0.000 title abstract 2
- 102000015081 Blood Coagulation Factors Human genes 0.000 title abstract 2
- 108010039209 Blood Coagulation Factors Proteins 0.000 title abstract 2
- 102000015395 alpha 1-Antitrypsin Human genes 0.000 title abstract 2
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 title abstract 2
- 239000003114 blood coagulation factor Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/14—Evaporating with heated gases or vapours or liquids in contact with the liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/16—Evaporating by spraying
- B01D1/18—Evaporating by spraying to obtain dry solids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8128—Antithrombin III
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
MÉTODO DE FRACIONAMENTO DE PLASMA HUMANO, COMPOSIÇÃO, E, PREPARAÇÕES DE UM FATOR DE COAGULAÇÃO, DE IGG, DE UM MEMBRO SELECIONADO DE A1PI, AT-III E UMA COMBINAÇÃO DOS MESMOS E DE ALBUMINA. A presente invenção fornece um método de fracionamento de plasma humano, em algumas modalidades, usando o procedimento de fracionamento de Cohn. A melhoria compreende o uso de plasma humano seco por pulverização reconstituído fisiologicamente ativo como material de partida para o procedimento de fracionamento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063086335P | 2020-10-01 | 2020-10-01 | |
PCT/IB2021/000680 WO2022069945A1 (en) | 2020-10-01 | 2021-10-01 | Plasma fractionation process utilizing spray-dried human plasma |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112023003010A2 true BR112023003010A2 (pt) | 2023-04-04 |
Family
ID=79170928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112023003010A BR112023003010A2 (pt) | 2020-10-01 | 2021-10-01 | Método de fracionamento de plasma humano, composição, e, preparações de um fator de coagulação, de igg, de um membro selecionado de a1pi, at-iii e uma combinação dos mesmos e de albumina |
Country Status (12)
Country | Link |
---|---|
US (1) | US20220106357A1 (pt) |
EP (1) | EP4222161A1 (pt) |
JP (1) | JP2023545948A (pt) |
KR (1) | KR20230078629A (pt) |
CN (1) | CN116096385A (pt) |
AU (1) | AU2021354979A1 (pt) |
BR (1) | BR112023003010A2 (pt) |
CA (1) | CA3189976A1 (pt) |
CO (1) | CO2023001489A2 (pt) |
IL (1) | IL300384A (pt) |
MX (1) | MX2023003483A (pt) |
WO (1) | WO2022069945A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9561184B2 (en) | 2014-09-19 | 2017-02-07 | Velico Medical, Inc. | Methods and systems for multi-stage drying of plasma |
US11841189B1 (en) * | 2022-09-15 | 2023-12-12 | Velico Medical, Inc. | Disposable for a spray drying system |
US11975274B2 (en) | 2022-09-15 | 2024-05-07 | Velico Medical, Inc. | Blood plasma product |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8407912B2 (en) * | 2010-09-16 | 2013-04-02 | Velico Medical, Inc. | Spray dried human plasma |
AU2010202125B1 (en) * | 2010-05-26 | 2010-09-02 | Takeda Pharmaceutical Company Limited | A method to produce an immunoglobulin preparation with improved yield |
US20140083627A1 (en) * | 2012-09-27 | 2014-03-27 | Velico Medical, Inc. | Automated spray drier |
-
2021
- 2021-10-01 MX MX2023003483A patent/MX2023003483A/es unknown
- 2021-10-01 KR KR1020237005656A patent/KR20230078629A/ko unknown
- 2021-10-01 JP JP2023519301A patent/JP2023545948A/ja active Pending
- 2021-10-01 EP EP21835362.1A patent/EP4222161A1/en active Pending
- 2021-10-01 WO PCT/IB2021/000680 patent/WO2022069945A1/en active Application Filing
- 2021-10-01 AU AU2021354979A patent/AU2021354979A1/en active Pending
- 2021-10-01 CN CN202180054365.0A patent/CN116096385A/zh active Pending
- 2021-10-01 BR BR112023003010A patent/BR112023003010A2/pt unknown
- 2021-10-01 IL IL300384A patent/IL300384A/en unknown
- 2021-10-01 CA CA3189976A patent/CA3189976A1/en active Pending
- 2021-10-01 US US17/492,256 patent/US20220106357A1/en active Pending
-
2023
- 2023-02-10 CO CONC2023/0001489A patent/CO2023001489A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CA3189976A1 (en) | 2022-04-07 |
US20220106357A1 (en) | 2022-04-07 |
EP4222161A1 (en) | 2023-08-09 |
CO2023001489A2 (es) | 2023-02-16 |
IL300384A (en) | 2023-04-01 |
MX2023003483A (es) | 2023-04-14 |
AU2021354979A1 (en) | 2023-02-23 |
WO2022069945A1 (en) | 2022-04-07 |
CN116096385A (zh) | 2023-05-09 |
KR20230078629A (ko) | 2023-06-02 |
JP2023545948A (ja) | 2023-11-01 |
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